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The map label for this gene is maeB [H]

Identifier: 238024826

GI number: 238024826

Start: 1863566

End: 1865851

Strand: Reverse

Name: maeB [H]

Synonym: bglu_2g14660

Alternate gene names: 238024826

Gene position: 1865851-1863566 (Counterclockwise)

Preceding gene: 238024828

Following gene: 238024823

Centisome position: 65.99

GC content: 67.41

Gene sequence:

>2286_bases
ATGAACAAGACCGACCGCCAGGCCGCCCTGGAATACCACCAGTACCCCACGCCGGGGAAGATTTCCGTGACCGCCAGCAA
GCCGCTCGTCACGCAGCGCGACCTCGCGCTCGCCTATACGCCGGGCGTGGCGGTGGCCTGCGAGGAAATCGTCGAGAACC
CGGCCAACGCGTTCAACTACACGAGCCGCGGCAACCTGGTGGGCGTGATCACCAACGGCAGCGCGGTGCTCGGCCTCGGC
AATATCGGCGCGCTGGCCTCCAAGCCGGTGATGGAGGGCAAGGCGGTGCTGTTCAAGAAGTTCGCCGGCATCGACGTGTT
CGACATCGAGATCACCGAGTCCGACCCGGACAAGCTGGTCGACATCATCGCGAGCCTGGAGGCTACCTTCGGCGGCATCA
ACCTCGAGGACATCAAGGCGCCCGAGTGCTTCACGGTCGAGCGCAAGCTGCGCGAGCGCATGAAGATCCCGGTCTTCCAC
GACGACCAGCACGGCACCGCGATCACCGTCAGTGCCGCCTTCATCAACGGCCTGAAGGTGGTCGGCAAGGACATCAAGCA
GGTGAAGGTGGTGACCTCCGGCGCGGGCGCGGCCGCGCTCGCCTGCCTCGACCTGATGGTCGATCTCGGCCTGCCGATCG
AGAACATCTGGGCCACCGACATCGACGGCGTGGTCTACCGGGGCCGTACCACGCTGATGGACCCGGACAAGGCGCGCTTC
GCGCAGGACACCGCGGCGCGCACGCTTGACGAGGTGATCGAGGGGGCCGACGTGTTCCTCGGCCTGTCGGCGGGCGGCGT
GCTGAAGGCGCCGATGCTCGCGAAGATGGCGAAGAACCCGCTGATCCTCGCGCTCGCGAATCCGACGCCGGAAATCTTCC
CCGAACTCGCGCATGCCACGCGCGACGACGTGGTGATCGCCACCGGCCGCTCGGACTTCCCGAACCAGGTCAACAACGTG
CTGTGCTTCCCGTACATCTTCCGCGGCGCGCTCGACGTGGGCGCCACCACCATCACGCGGCGCATGGAGATCGCGGCGGT
CCACGCGATCGCGGGGCTGGCCGAGGAGGAGCCGAACGACTCGGTGGCCGCCGCCTACGGCGCCTACGATCTGTCGTTCG
GGCCGAAGTACCTGATCCCGAAGCCGTTCGACTCGCGGCTGCTGCTGCGCATCGCGCCGGCGGTGGCCAAGGCCGCCATC
GAGGAAGGCGTGGCCACGCGTCCGATCGACGATTTCGCCGCCTATGCCGACCAGCTGCAGCAGTTCGTCTACCACTCGGG
CGCGTTCATGAAGCCGTTGTTCTCGGCGGCCAAGCAGTTCGTGCGCGACGGCGCGAAGACGCGCATCGTGTTCGCCGAGG
GCGAGGAGGAGCGCGTGCTGCGCGCGGTGCAGGTGATCGTCGACGAGAAGCTGGCGCGGCCGATCCTGATCGGCCGCCCC
GAGGTGCTGCTCGCGCGGATCGAGAAGTTCGGGCTGCGCCTGAAGCTCGGCGAGGACGTGGAGGTGACCAACCCCGAGTA
CGACGAGCGCTTCCATCAGTACTGGACGACCTACTGGGAGCTGCGCTGCCGTGACGGCATCACCAAGGAGATGGCGCGCG
TGGAAATGCGCCGGCGCCTGACGCTGATCGGCGCGATGATGGTGAGGCTCGGCGATGCGGACGGCATGATCTGCGGCACG
GTGGGCGCCTATCACGACCATCTGCGCTTCGTCGACGAGGTTATCGGCAAGGCGCGCGGCGCGCGCACCTACGGCGCGAT
GAACATCCTGCTGCTGGACAAGCGCACCGTCGCGCTGGTGGACACGCACATCAACGACAATCCGAACGCGGACCAGATCG
CCGAGTTCACGATTGCGGCGGCCTCGCAGATGGCGTGGCTGAACCTCTCGCCGAAGGTCGCGCTGCTGTCGCGCTCGAAC
TTCGGCTCGGGCAGCTCGGCCTCGGGCGCGAAGATGCGCGAGGTGCTGGAGCTCGTGAAGGAGCGCGCGCCGGACCTCGA
GATCGAGGGCGAAATGCACGGCGACTGCGCGCTCGACGAGACGCTGCGCCAGCGCTTCCTGCCGCATTCGCGGCTCAAGG
GCGCGGCCAACCTGCTGGTCTGCCCGAACGTCGATGCTGGCAACATCGCCTACAACCTGCTGAAGACGAGCGCGGGCAGC
AACGTCGCGGTGGGCCCGTTCCTGCTCGGCGTGAACGCGCCCGTCAACATCATGACGGCCAGCTCGACGGTGCGCCGCAT
CGTCAACATGACTGCGCTGACCGTGCTGCAGGCCAATCGCGACTGA

Upstream 100 bases:

>100_bases
CCCATACTAATTCAAAATGGCGCACCCTTAGCGGCTGCCTAGAATCGCTTCCTCAGATCGCCGCCGGGACGGGCCCGGCG
CGGCCAACCCGAGTGAGACG

Downstream 100 bases:

>100_bases
GCGGCATCGATTCGCAGGCCCTTGCCCCCGGCGCTTGCATGGCCGCAGATCGAGCGCGGCGCCGCCGCGCTGCCGGATCT
GCCGGGCATCGGTTTCGAGG

Product: malic enzyme

Products: NA

Alternate protein names: NADP-ME [H]

Number of amino acids: Translated: 761; Mature: 761

Protein sequence:

>761_residues
MNKTDRQAALEYHQYPTPGKISVTASKPLVTQRDLALAYTPGVAVACEEIVENPANAFNYTSRGNLVGVITNGSAVLGLG
NIGALASKPVMEGKAVLFKKFAGIDVFDIEITESDPDKLVDIIASLEATFGGINLEDIKAPECFTVERKLRERMKIPVFH
DDQHGTAITVSAAFINGLKVVGKDIKQVKVVTSGAGAAALACLDLMVDLGLPIENIWATDIDGVVYRGRTTLMDPDKARF
AQDTAARTLDEVIEGADVFLGLSAGGVLKAPMLAKMAKNPLILALANPTPEIFPELAHATRDDVVIATGRSDFPNQVNNV
LCFPYIFRGALDVGATTITRRMEIAAVHAIAGLAEEEPNDSVAAAYGAYDLSFGPKYLIPKPFDSRLLLRIAPAVAKAAI
EEGVATRPIDDFAAYADQLQQFVYHSGAFMKPLFSAAKQFVRDGAKTRIVFAEGEEERVLRAVQVIVDEKLARPILIGRP
EVLLARIEKFGLRLKLGEDVEVTNPEYDERFHQYWTTYWELRCRDGITKEMARVEMRRRLTLIGAMMVRLGDADGMICGT
VGAYHDHLRFVDEVIGKARGARTYGAMNILLLDKRTVALVDTHINDNPNADQIAEFTIAAASQMAWLNLSPKVALLSRSN
FGSGSSASGAKMREVLELVKERAPDLEIEGEMHGDCALDETLRQRFLPHSRLKGAANLLVCPNVDAGNIAYNLLKTSAGS
NVAVGPFLLGVNAPVNIMTASSTVRRIVNMTALTVLQANRD

Sequences:

>Translated_761_residues
MNKTDRQAALEYHQYPTPGKISVTASKPLVTQRDLALAYTPGVAVACEEIVENPANAFNYTSRGNLVGVITNGSAVLGLG
NIGALASKPVMEGKAVLFKKFAGIDVFDIEITESDPDKLVDIIASLEATFGGINLEDIKAPECFTVERKLRERMKIPVFH
DDQHGTAITVSAAFINGLKVVGKDIKQVKVVTSGAGAAALACLDLMVDLGLPIENIWATDIDGVVYRGRTTLMDPDKARF
AQDTAARTLDEVIEGADVFLGLSAGGVLKAPMLAKMAKNPLILALANPTPEIFPELAHATRDDVVIATGRSDFPNQVNNV
LCFPYIFRGALDVGATTITRRMEIAAVHAIAGLAEEEPNDSVAAAYGAYDLSFGPKYLIPKPFDSRLLLRIAPAVAKAAI
EEGVATRPIDDFAAYADQLQQFVYHSGAFMKPLFSAAKQFVRDGAKTRIVFAEGEEERVLRAVQVIVDEKLARPILIGRP
EVLLARIEKFGLRLKLGEDVEVTNPEYDERFHQYWTTYWELRCRDGITKEMARVEMRRRLTLIGAMMVRLGDADGMICGT
VGAYHDHLRFVDEVIGKARGARTYGAMNILLLDKRTVALVDTHINDNPNADQIAEFTIAAASQMAWLNLSPKVALLSRSN
FGSGSSASGAKMREVLELVKERAPDLEIEGEMHGDCALDETLRQRFLPHSRLKGAANLLVCPNVDAGNIAYNLLKTSAGS
NVAVGPFLLGVNAPVNIMTASSTVRRIVNMTALTVLQANRD
>Mature_761_residues
MNKTDRQAALEYHQYPTPGKISVTASKPLVTQRDLALAYTPGVAVACEEIVENPANAFNYTSRGNLVGVITNGSAVLGLG
NIGALASKPVMEGKAVLFKKFAGIDVFDIEITESDPDKLVDIIASLEATFGGINLEDIKAPECFTVERKLRERMKIPVFH
DDQHGTAITVSAAFINGLKVVGKDIKQVKVVTSGAGAAALACLDLMVDLGLPIENIWATDIDGVVYRGRTTLMDPDKARF
AQDTAARTLDEVIEGADVFLGLSAGGVLKAPMLAKMAKNPLILALANPTPEIFPELAHATRDDVVIATGRSDFPNQVNNV
LCFPYIFRGALDVGATTITRRMEIAAVHAIAGLAEEEPNDSVAAAYGAYDLSFGPKYLIPKPFDSRLLLRIAPAVAKAAI
EEGVATRPIDDFAAYADQLQQFVYHSGAFMKPLFSAAKQFVRDGAKTRIVFAEGEEERVLRAVQVIVDEKLARPILIGRP
EVLLARIEKFGLRLKLGEDVEVTNPEYDERFHQYWTTYWELRCRDGITKEMARVEMRRRLTLIGAMMVRLGDADGMICGT
VGAYHDHLRFVDEVIGKARGARTYGAMNILLLDKRTVALVDTHINDNPNADQIAEFTIAAASQMAWLNLSPKVALLSRSN
FGSGSSASGAKMREVLELVKERAPDLEIEGEMHGDCALDETLRQRFLPHSRLKGAANLLVCPNVDAGNIAYNLLKTSAGS
NVAVGPFLLGVNAPVNIMTASSTVRRIVNMTALTVLQANRD

Specific function: Unknown

COG id: COG0281

COG function: function code C; Malic enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4505143, Length=397, Percent_Identity=24.9370277078086, Blast_Score=90, Evalue=9e-18,
Organism=Homo sapiens, GI4505145, Length=404, Percent_Identity=26.2376237623762, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI270265879, Length=370, Percent_Identity=27.027027027027, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI62420882, Length=403, Percent_Identity=25.0620347394541, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI62420880, Length=403, Percent_Identity=25.0620347394541, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI239049447, Length=403, Percent_Identity=25.0620347394541, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI1788806, Length=760, Percent_Identity=58.9473684210526, Blast_Score=914, Evalue=0.0,
Organism=Escherichia coli, GI1788635, Length=316, Percent_Identity=30.379746835443, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1788800, Length=312, Percent_Identity=29.8076923076923, Blast_Score=129, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17537199, Length=455, Percent_Identity=24.6153846153846, Blast_Score=79, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322823, Length=290, Percent_Identity=30.6896551724138, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281362674, Length=508, Percent_Identity=27.3622047244095, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI21356279, Length=474, Percent_Identity=27.8481012658228, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281362672, Length=474, Percent_Identity=27.8481012658228, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646388, Length=474, Percent_Identity=27.6371308016878, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646386, Length=474, Percent_Identity=27.6371308016878, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281363505, Length=356, Percent_Identity=26.685393258427, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI78707236, Length=356, Percent_Identity=26.685393258427, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI78707232, Length=356, Percent_Identity=26.685393258427, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281363503, Length=356, Percent_Identity=26.685393258427, Blast_Score=73, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015884
- InterPro:   IPR012301
- InterPro:   IPR012302
- InterPro:   IPR012188
- InterPro:   IPR016040
- InterPro:   IPR002505 [H]

Pfam domain/function: PF00390 malic; PF03949 Malic_M; PF01515 PTA_PTB [H]

EC number: =1.1.1.40 [H]

Molecular weight: Translated: 82559; Mature: 82559

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTDRQAALEYHQYPTPGKISVTASKPLVTQRDLALAYTPGVAVACEEIVENPANAFNY
CCCCHHHHHHHHHCCCCCCEEEEEECCCCCEECCEEEEECCCHHHHHHHHHCCCHHHCCC
TSRGNLVGVITNGSAVLGLGNIGALASKPVMEGKAVLFKKFAGIDVFDIEITESDPDKLV
CCCCCEEEEEECCCEEEEECCCCHHHCCCCCCCHHHHHHHHCCCEEEEEEECCCCHHHHH
DIIASLEATFGGINLEDIKAPECFTVERKLRERMKIPVFHDDQHGTAITVSAAFINGLKV
HHHHHHHHHCCCCCHHHCCCCCEEHHHHHHHHHCCCCEEECCCCCCEEEEEHHHHHHHHH
VGKDIKQVKVVTSGAGAAALACLDLMVDLGLPIENIWATDIDGVVYRGRTTLMDPDKARF
HCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCEEECCCEECCCCHHHHH
AQDTAARTLDEVIEGADVFLGLSAGGVLKAPMLAKMAKNPLILALANPTPEIFPELAHAT
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCC
RDDVVIATGRSDFPNQVNNVLCFPYIFRGALDVGATTITRRMEIAAVHAIAGLAEEEPND
CCCEEEEECCCCCCHHHHCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC
SVAAAYGAYDLSFGPKYLIPKPFDSRLLLRIAPAVAKAAIEEGVATRPIDDFAAYADQLQ
CEEEEECCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
QFVYHSGAFMKPLFSAAKQFVRDGAKTRIVFAEGEEERVLRAVQVIVDEKLARPILIGRP
HHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEECCCH
EVLLARIEKFGLRLKLGEDVEVTNPEYDERFHQYWTTYWELRCRDGITKEMARVEMRRRL
HHHHHHHHHHCEEEEECCCCCCCCCHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHH
TLIGAMMVRLGDADGMICGTVGAYHDHLRFVDEVIGKARGARTYGAMNILLLDKRTVALV
HHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEE
DTHINDNPNADQIAEFTIAAASQMAWLNLSPKVALLSRSNFGSGSSASGAKMREVLELVK
EECCCCCCCHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
ERAPDLEIEGEMHGDCALDETLRQRFLPHSRLKGAANLLVCPNVDAGNIAYNLLKTSAGS
HCCCCCEECCCCCCCCHHHHHHHHHCCCHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCC
NVAVGPFLLGVNAPVNIMTASSTVRRIVNMTALTVLQANRD
CEEECEEEEECCCCEEEEECHHHHHHHHHHHHHEEEECCCC
>Mature Secondary Structure
MNKTDRQAALEYHQYPTPGKISVTASKPLVTQRDLALAYTPGVAVACEEIVENPANAFNY
CCCCHHHHHHHHHCCCCCCEEEEEECCCCCEECCEEEEECCCHHHHHHHHHCCCHHHCCC
TSRGNLVGVITNGSAVLGLGNIGALASKPVMEGKAVLFKKFAGIDVFDIEITESDPDKLV
CCCCCEEEEEECCCEEEEECCCCHHHCCCCCCCHHHHHHHHCCCEEEEEEECCCCHHHHH
DIIASLEATFGGINLEDIKAPECFTVERKLRERMKIPVFHDDQHGTAITVSAAFINGLKV
HHHHHHHHHCCCCCHHHCCCCCEEHHHHHHHHHCCCCEEECCCCCCEEEEEHHHHHHHHH
VGKDIKQVKVVTSGAGAAALACLDLMVDLGLPIENIWATDIDGVVYRGRTTLMDPDKARF
HCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCEEECCCEECCCCHHHHH
AQDTAARTLDEVIEGADVFLGLSAGGVLKAPMLAKMAKNPLILALANPTPEIFPELAHAT
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCC
RDDVVIATGRSDFPNQVNNVLCFPYIFRGALDVGATTITRRMEIAAVHAIAGLAEEEPND
CCCEEEEECCCCCCHHHHCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC
SVAAAYGAYDLSFGPKYLIPKPFDSRLLLRIAPAVAKAAIEEGVATRPIDDFAAYADQLQ
CEEEEECCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
QFVYHSGAFMKPLFSAAKQFVRDGAKTRIVFAEGEEERVLRAVQVIVDEKLARPILIGRP
HHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEECCCH
EVLLARIEKFGLRLKLGEDVEVTNPEYDERFHQYWTTYWELRCRDGITKEMARVEMRRRL
HHHHHHHHHHCEEEEECCCCCCCCCHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHH
TLIGAMMVRLGDADGMICGTVGAYHDHLRFVDEVIGKARGARTYGAMNILLLDKRTVALV
HHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEE
DTHINDNPNADQIAEFTIAAASQMAWLNLSPKVALLSRSNFGSGSSASGAKMREVLELVK
EECCCCCCCHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
ERAPDLEIEGEMHGDCALDETLRQRFLPHSRLKGAANLLVCPNVDAGNIAYNLLKTSAGS
HCCCCCEECCCCCCCCHHHHHHHHHCCCHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCC
NVAVGPFLLGVNAPVNIMTASSTVRRIVNMTALTVLQANRD
CEEECEEEEECCCCEEEEECHHHHHHHHHHHHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 36376 [H]