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The map label for this gene is ribA [H]

Identifier: 238024820

GI number: 238024820

Start: 1856750

End: 1857409

Strand: Reverse

Name: ribA [H]

Synonym: bglu_2g14580

Alternate gene names: 238024820

Gene position: 1857409-1856750 (Counterclockwise)

Preceding gene: 238024822

Following gene: 238024819

Centisome position: 65.69

GC content: 64.24

Gene sequence:

>660_bases
CTGATGTTTTCCATGCCTTCGCATCCCGTATTGCCCCCGGCCAACGAGCATCCGGCCGACGAGCCCGTGACGCTCGTCGC
GTCGGCATCTTTGCCGACGCGCTATGGCGTATTCACGTCTCATGCATTTCGCGTCGACGGTAGCCAGGCCGAACATCTGG
CACTCGTGGTGGGCGACGTCGCCGGGCGGCAACCGGTGCTGACGCGGCTGCATTCGGAGTGCCTGACGGGCGACGTGTTC
GGCTCGTATCGCTGCGATTGCGGCGAGCAACTCGATCTTGCACTGCGCAATATCGTCGCCGAAGGTCGCGGCGTCCTGCT
GTACCTGCGCGGCCACGAAGGTCGCGGCATTGGCCTGAGCAACAAGATTCGCGCATACGCGCTGCAGGAGCAGGGGCGCG
ATACGGTCGAGGCGAATCGCGACCTCGGGCTGCCCGACGACGCGCGCGAGTACGACTCGGCCGCGGCGATCCTGCGGATT
CTCGGCGTCACCTCGGTGCGGCTGATGAGCAACAACCCTAAGAAGTTCGACACGCTGGTGGCGCACGGCATTCCCGTTTG
CGAACGCGTGGCGCTGCCGGTGCCGATGCGCGACGAGAACGAGCGGTATATCCGGACCAAACAGGCCAAGTTCGGGCATT
ACTTCGACGAGAACGAATAA

Upstream 100 bases:

>100_bases
GAGACGTTCGCGCCCCATGGACGGGGTGCAGAACGCATAACGTAGATTAGCGGTAAACTCCGCCTGCGCGCTACTCCAAA
CATCCCTTAACTCCGAATTC

Downstream 100 bases:

>100_bases
CCGTTTCCGGGCCCCCAGCGGGGCCCTTGTCGTATCTGGGCAGAGGCGCCGGCGTGCCTGACTGGCAAGGCATCGATGTA
TCGTCCGATGAAGACCTGCT

Product: GTP cyclohydrolase II

Products: NA

Alternate protein names: GTP cyclohydrolase II [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MMFSMPSHPVLPPANEHPADEPVTLVASASLPTRYGVFTSHAFRVDGSQAEHLALVVGDVAGRQPVLTRLHSECLTGDVF
GSYRCDCGEQLDLALRNIVAEGRGVLLYLRGHEGRGIGLSNKIRAYALQEQGRDTVEANRDLGLPDDAREYDSAAAILRI
LGVTSVRLMSNNPKKFDTLVAHGIPVCERVALPVPMRDENERYIRTKQAKFGHYFDENE

Sequences:

>Translated_219_residues
MMFSMPSHPVLPPANEHPADEPVTLVASASLPTRYGVFTSHAFRVDGSQAEHLALVVGDVAGRQPVLTRLHSECLTGDVF
GSYRCDCGEQLDLALRNIVAEGRGVLLYLRGHEGRGIGLSNKIRAYALQEQGRDTVEANRDLGLPDDAREYDSAAAILRI
LGVTSVRLMSNNPKKFDTLVAHGIPVCERVALPVPMRDENERYIRTKQAKFGHYFDENE
>Mature_219_residues
MMFSMPSHPVLPPANEHPADEPVTLVASASLPTRYGVFTSHAFRVDGSQAEHLALVVGDVAGRQPVLTRLHSECLTGDVF
GSYRCDCGEQLDLALRNIVAEGRGVLLYLRGHEGRGIGLSNKIRAYALQEQGRDTVEANRDLGLPDDAREYDSAAAILRI
LGVTSVRLMSNNPKKFDTLVAHGIPVCERVALPVPMRDENERYIRTKQAKFGHYFDENE

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0807

COG function: function code H; GTP cyclohydrolase II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1787533, Length=192, Percent_Identity=53.125, Blast_Score=197, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6319438, Length=199, Percent_Identity=41.7085427135678, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000926 [H]

Pfam domain/function: PF00925 GTP_cyclohydro2 [H]

EC number: =3.5.4.25 [H]

Molecular weight: Translated: 24139; Mature: 24139

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFSMPSHPVLPPANEHPADEPVTLVASASLPTRYGVFTSHAFRVDGSQAEHLALVVGDV
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEECEEEEECCCCCCEEEEEEECC
AGRQPVLTRLHSECLTGDVFGSYRCDCGEQLDLALRNIVAEGRGVLLYLRGHEGRGIGLS
CCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
NKIRAYALQEQGRDTVEANRDLGLPDDAREYDSAAAILRILGVTSVRLMSNNPKKFDTLV
CCHHEEEEHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHH
AHGIPVCERVALPVPMRDENERYIRTKQAKFGHYFDENE
HCCCCHHHHHCCCCCCCCCCCCEEEEHHHHCCCCCCCCC
>Mature Secondary Structure
MMFSMPSHPVLPPANEHPADEPVTLVASASLPTRYGVFTSHAFRVDGSQAEHLALVVGDV
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEECEEEEECCCCCCEEEEEEECC
AGRQPVLTRLHSECLTGDVFGSYRCDCGEQLDLALRNIVAEGRGVLLYLRGHEGRGIGLS
CCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
NKIRAYALQEQGRDTVEANRDLGLPDDAREYDSAAAILRILGVTSVRLMSNNPKKFDTLV
CCHHEEEEHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHH
AHGIPVCERVALPVPMRDENERYIRTKQAKFGHYFDENE
HCCCCHHHHHCCCCCCCCCCCCEEEEHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA