| Definition | Burkholderia glumae BGR1 chromosome chromosome 2, complete sequence. |
|---|---|
| Accession | NC_012721 |
| Length | 2,827,333 |
Click here to switch to the map view.
The map label for this gene is pbpC [H]
Identifier: 238024626
GI number: 238024626
Start: 1586491
End: 1588878
Strand: Direct
Name: pbpC [H]
Synonym: bglu_2g12410
Alternate gene names: 238024626
Gene position: 1586491-1588878 (Clockwise)
Preceding gene: 238024625
Following gene: 238024630
Centisome position: 56.11
GC content: 75.67
Gene sequence:
>2388_bases GTGAGCGGGGCGCGTTCGCGCGCCTGGGGGCGGCGCGCCGCGAAGCCGCCCGGCGGCCTGCCCGGGCGGCCGCTTGGCGG GGCGCCCCGCCTGCGCCTGCTGCGCGTGCTGGCGGGCGCGCTGTGCCTCGGCACGGCCACGCTCGCCTGCGCCGTGCCGA GCTACGACGCGGTGCGCCGCGACTGGCGCAGCTCCGACTGGATCCTGCTCGCGCGCGACGGCACGCCGTTGCAGCGCACG CGGATCGACAACGGCGAGCGGCGCGGCGACTGGGTCGCGCTGGCCGACGTCTCGCCCGCGCTGCGCGAGGCCATCGTGGT ATCCGAGGACAAGCGCTTCTACGCGCACAGCGGCGTGGACTGGCGCGGCATCGCCGGCGCCGCCTGGGCGAACCTCTGGA ACGCGCGCACCCGCGGCGCCTCCACCGTCACCATGCAACTGGCCGGCCTGCTCGGCGACGACGCGCGCCGCTCGGGCCAG CGCTCGCTGCCGCAGAAGGCCGGCCAGGCGCTCGACGCGCTGTGGCTGGAACGCACCTGGCGCAAGGATCAGATCCTCGA GGCCTACCTGAACCTGGTGCCGTTCCGCGGCGAGGCCGTGGGCCTGTCGGCGCTGTCGTACACGCTGTTCGGCAAGGCGC CGTCCGGCCTCGACGAGCGCGAATCGGCGGTGGCCGCCGCGCTGATCCGCGCGCCGAACGCACCGTACCCCAAAGTGGCC GAGCGCGCCTGCCGGATCCTGCGCGACATGCAGGCCGCGCCGCGCTGCGCCGGCCTCGACGGCTTCGTGCAGCTCGCGTT CGCGCGGCCGGCCACGCCGTCGTCGGCGTTCCTCGATGGCGAGGCGCTCGCGCCGCATTTCGCGCGGCGCGTGGCGGCGC AGGTGCGGCCGCAGGCCGGCGCGCGCGTGCGCTCGACGCTCGATGCCGGCCTGCAGCGCTTCACGCGCGACACCCTCACG CGCACGCTGATCGAGCTGAACGCCCCGCCGCAGTCGCGCGACGTGCAGGACGGCGCGGCGGTGGTGATCGACAACCGCAG CGGCGAGATCCTCGCCTGGGTCGGCTCGTCGGGCGCGCTGTCGGCCGCGCGCGAGGTGGACGCCGTGCTGGCGCTGCGCC AGGCCGGCTCCACGCTCAAGCCGTTCCTCTACGCGCAGGCGATCGACGAACGGCGCGTGACGGGTGCCACGCTGCTCGAC GATTCGCCCGTCGATCTCGCCGCCGGCGGCGGCCTCTACGTGCCGCAGAACTACGATCACGATTTCAAGGGCTGGGTCAG CGTGCGCAGCGCGCTCGGCTCCTCGCTGAACGTGCCGGCCGTGCGCACGCTGGTGCTGGTCACGCCGCACCGCTTCTCGA AGACGCTGACCGCGCTCGGCCTGCCGCTGACCGAACAGGGCGACTACTACGGCTACAGCCTCGCGCTCGGCAGCGCCGAC GTCTCGCTGCTCACGCTCGCCAACGCCTACCGCGCGCTCGCCAACGGCGGCGTCGCGCGGCCCACCTTCGACCTGCCGCG CAGCACCGCGCCGGGCGCCGCGCCAAGGCCGGCGCCGGCGGGCCGGCGCGTGTTCAGCGCCGACGCGAGCTTCATCGTCA CCGACATGCTCGCCGACAACAACGCGCGCACGCGCACCTTCGGCTTCGACAGCCCGCTCGCCACGCACGCGTTCTCGGCC GTCAAGACCGGCACCAGCAAGGACATGCGCGACAACTGGGCGGTCGGCTTCACGTCGCGCTATACGGTGGGCGTGTGGGT GGGCAACGCCGACGGCGCGCCGATGCGCAACGTATCGGGCGTGACGGGCGCCGCACCGGTATGGGCCGCGATCGTCGCGC GGCTGCATCGCGACGGCGGCAGCGTCGCGCCCACCGCGCCGCCCGGCGTGGTGCGCGAGCGCGTGAGCTTCGAGCGCGCG ATCGAGCCCACCCGCGACGAGTGGTTCCTGCGCGGCACCGAGACCACCGAGGTGCGGCTCGCGGCCGGCGCGGGCGGCGA GCCGGCTGCGCCGGCCGCGAGCCGCGCGAGGCCGGCCGGACACGTGCGCACCGTGTCCGCCGGCACGGCCGGCCTGGCGC CGCGCGCGCCGCTGGCGATCGCCGCCCCCACCGACGGCACGATCTTCGCCGTCGATCCGGACATCCCGCCGCGCAACCAG CGCGTCTGGTTCGAGCGCGTGGCCGGCAACAGCGGGCGCGGCAGCTGGCGGCTGGACGGCCGCGTGATCGGACACGGCGA ACGCGTGGCATGGCTGCCGTGGCCGGGACGTCACACGCTGGAACTGCTCGATGCCGACGGCAAGGTGGCCGACCATGTGG CATTCGAGGTGCGTGGCGCCGTGGCCAAGCCCGGCGCTGCGGCGGGGGCGGCGGCGCGGGCTCGCTGA
Upstream 100 bases:
>100_bases GCCTGCCGCCGACGCGCGTGGAGGCGCTCTACGCGCCGTCGGCATACGGCCTGACGCCGAACGCGCCGGTGGTGGTGCGG CCGGCCGCGGACGCCCGGCC
Downstream 100 bases:
>100_bases GCGGGCCGCGGGCGGGCACGCCGGCGCGCCGCAGACGCCCCTCGATGCGGCGGGCAAGCCTCGTCGCCGGCTGCATCGAC GGATCGACTGATCGACTGAT
Product: Penicillin-binding protein 1C
Products: NA
Alternate protein names: PBP-1c; PBP1c; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Transpeptidase-like module [H]
Number of amino acids: Translated: 795; Mature: 794
Protein sequence:
>795_residues MSGARSRAWGRRAAKPPGGLPGRPLGGAPRLRLLRVLAGALCLGTATLACAVPSYDAVRRDWRSSDWILLARDGTPLQRT RIDNGERRGDWVALADVSPALREAIVVSEDKRFYAHSGVDWRGIAGAAWANLWNARTRGASTVTMQLAGLLGDDARRSGQ RSLPQKAGQALDALWLERTWRKDQILEAYLNLVPFRGEAVGLSALSYTLFGKAPSGLDERESAVAAALIRAPNAPYPKVA ERACRILRDMQAAPRCAGLDGFVQLAFARPATPSSAFLDGEALAPHFARRVAAQVRPQAGARVRSTLDAGLQRFTRDTLT RTLIELNAPPQSRDVQDGAAVVIDNRSGEILAWVGSSGALSAAREVDAVLALRQAGSTLKPFLYAQAIDERRVTGATLLD DSPVDLAAGGGLYVPQNYDHDFKGWVSVRSALGSSLNVPAVRTLVLVTPHRFSKTLTALGLPLTEQGDYYGYSLALGSAD VSLLTLANAYRALANGGVARPTFDLPRSTAPGAAPRPAPAGRRVFSADASFIVTDMLADNNARTRTFGFDSPLATHAFSA VKTGTSKDMRDNWAVGFTSRYTVGVWVGNADGAPMRNVSGVTGAAPVWAAIVARLHRDGGSVAPTAPPGVVRERVSFERA IEPTRDEWFLRGTETTEVRLAAGAGGEPAAPAASRARPAGHVRTVSAGTAGLAPRAPLAIAAPTDGTIFAVDPDIPPRNQ RVWFERVAGNSGRGSWRLDGRVIGHGERVAWLPWPGRHTLELLDADGKVADHVAFEVRGAVAKPGAAAGAAARAR
Sequences:
>Translated_795_residues MSGARSRAWGRRAAKPPGGLPGRPLGGAPRLRLLRVLAGALCLGTATLACAVPSYDAVRRDWRSSDWILLARDGTPLQRT RIDNGERRGDWVALADVSPALREAIVVSEDKRFYAHSGVDWRGIAGAAWANLWNARTRGASTVTMQLAGLLGDDARRSGQ RSLPQKAGQALDALWLERTWRKDQILEAYLNLVPFRGEAVGLSALSYTLFGKAPSGLDERESAVAAALIRAPNAPYPKVA ERACRILRDMQAAPRCAGLDGFVQLAFARPATPSSAFLDGEALAPHFARRVAAQVRPQAGARVRSTLDAGLQRFTRDTLT RTLIELNAPPQSRDVQDGAAVVIDNRSGEILAWVGSSGALSAAREVDAVLALRQAGSTLKPFLYAQAIDERRVTGATLLD DSPVDLAAGGGLYVPQNYDHDFKGWVSVRSALGSSLNVPAVRTLVLVTPHRFSKTLTALGLPLTEQGDYYGYSLALGSAD VSLLTLANAYRALANGGVARPTFDLPRSTAPGAAPRPAPAGRRVFSADASFIVTDMLADNNARTRTFGFDSPLATHAFSA VKTGTSKDMRDNWAVGFTSRYTVGVWVGNADGAPMRNVSGVTGAAPVWAAIVARLHRDGGSVAPTAPPGVVRERVSFERA IEPTRDEWFLRGTETTEVRLAAGAGGEPAAPAASRARPAGHVRTVSAGTAGLAPRAPLAIAAPTDGTIFAVDPDIPPRNQ RVWFERVAGNSGRGSWRLDGRVIGHGERVAWLPWPGRHTLELLDADGKVADHVAFEVRGAVAKPGAAAGAAARAR >Mature_794_residues SGARSRAWGRRAAKPPGGLPGRPLGGAPRLRLLRVLAGALCLGTATLACAVPSYDAVRRDWRSSDWILLARDGTPLQRTR IDNGERRGDWVALADVSPALREAIVVSEDKRFYAHSGVDWRGIAGAAWANLWNARTRGASTVTMQLAGLLGDDARRSGQR SLPQKAGQALDALWLERTWRKDQILEAYLNLVPFRGEAVGLSALSYTLFGKAPSGLDERESAVAAALIRAPNAPYPKVAE RACRILRDMQAAPRCAGLDGFVQLAFARPATPSSAFLDGEALAPHFARRVAAQVRPQAGARVRSTLDAGLQRFTRDTLTR TLIELNAPPQSRDVQDGAAVVIDNRSGEILAWVGSSGALSAAREVDAVLALRQAGSTLKPFLYAQAIDERRVTGATLLDD SPVDLAAGGGLYVPQNYDHDFKGWVSVRSALGSSLNVPAVRTLVLVTPHRFSKTLTALGLPLTEQGDYYGYSLALGSADV SLLTLANAYRALANGGVARPTFDLPRSTAPGAAPRPAPAGRRVFSADASFIVTDMLADNNARTRTFGFDSPLATHAFSAV KTGTSKDMRDNWAVGFTSRYTVGVWVGNADGAPMRNVSGVTGAAPVWAAIVARLHRDGGSVAPTAPPGVVRERVSFERAI EPTRDEWFLRGTETTEVRLAAGAGGEPAAPAASRARPAGHVRTVSAGTAGLAPRAPLAIAAPTDGTIFAVDPDIPPRNQR VWFERVAGNSGRGSWRLDGRVIGHGERVAWLPWPGRHTLELLDADGKVADHVAFEVRGAVAKPGAAAGAAARAR
Specific function: Cell wall formation. The enzyme has a penicillin- insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a transpeptidase C-terminal domain which may not be functional [H]
COG id: COG4953
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein PbpC
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1788867, Length=552, Percent_Identity=35.1449275362319, Blast_Score=221, Evalue=2e-58, Organism=Escherichia coli, GI1786343, Length=554, Percent_Identity=26.173285198556, Blast_Score=117, Evalue=2e-27, Organism=Escherichia coli, GI87082258, Length=154, Percent_Identity=37.6623376623377, Blast_Score=87, Evalue=5e-18, Organism=Escherichia coli, GI1789601, Length=231, Percent_Identity=31.6017316017316, Blast_Score=74, Evalue=5e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011815 - InterPro: IPR009647 - InterPro: IPR001460 [H]
Pfam domain/function: PF06832 BiPBP_C; PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-
Molecular weight: Translated: 84282; Mature: 84151
Theoretical pI: Translated: 10.80; Mature: 10.80
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 1.3 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 0.6 %Met (Mature Protein) 1.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSGARSRAWGRRAAKPPGGLPGRPLGGAPRLRLLRVLAGALCLGTATLACAVPSYDAVRR CCCCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHH DWRSSDWILLARDGTPLQRTRIDNGERRGDWVALADVSPALREAIVVSEDKRFYAHSGVD HCCCCCEEEEECCCCCHHHHCCCCCCCCCCEEEEECCCHHHHHHEEEECCCCEEECCCCC WRGIAGAAWANLWNARTRGASTVTMQLAGLLGDDARRSGQRSLPQKAGQALDALWLERTW CCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHCCHHHHCCHHCCHHHHHHHHHHHHHHHHC RKDQILEAYLNLVPFRGEAVGLSALSYTLFGKAPSGLDERESAVAAALIRAPNAPYPKVA CHHHHHHHHHHHCCCCCCEECHHHHEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHH ERACRILRDMQAAPRCAGLDGFVQLAFARPATPSSAFLDGEALAPHFARRVAAQVRPQAG HHHHHHHHHHHCCCCCCCCHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC ARVRSTLDAGLQRFTRDTLTRTLIELNAPPQSRDVQDGAAVVIDNRSGEILAWVGSSGAL HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCH SAAREVDAVLALRQAGSTLKPFLYAQAIDERRVTGATLLDDSPVDLAAGGGLYVPQNYDH HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCEECCCCEECCCCCCC DFKGWVSVRSALGSSLNVPAVRTLVLVTPHRFSKTLTALGLPLTEQGDYYGYSLALGSAD CHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCC VSLLTLANAYRALANGGVARPTFDLPRSTAPGAAPRPAPAGRRVFSADASFIVTDMLADN CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEHHHCCC NARTRTFGFDSPLATHAFSAVKTGTSKDMRDNWAVGFTSRYTVGVWVGNADGAPMRNVSG CCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEEEECCCCCCCCCCCC VTGAAPVWAAIVARLHRDGGSVAPTAPPGVVRERVSFERAIEPTRDEWFLRGTETTEVRL CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEE AAGAGGEPAAPAASRARPAGHVRTVSAGTAGLAPRAPLAIAAPTDGTIFAVDPDIPPRNQ EECCCCCCCCCCHHCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCC RVWFERVAGNSGRGSWRLDGRVIGHGERVAWLPWPGRHTLELLDADGKVADHVAFEVRGA EEEEEECCCCCCCCCEEECCEEEECCCEEEEECCCCCCEEEEECCCCCHHHHHHEEECCC VAKPGAAAGAAARAR CCCCCCCCCCHHCCC >Mature Secondary Structure SGARSRAWGRRAAKPPGGLPGRPLGGAPRLRLLRVLAGALCLGTATLACAVPSYDAVRR CCCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHH DWRSSDWILLARDGTPLQRTRIDNGERRGDWVALADVSPALREAIVVSEDKRFYAHSGVD HCCCCCEEEEECCCCCHHHHCCCCCCCCCCEEEEECCCHHHHHHEEEECCCCEEECCCCC WRGIAGAAWANLWNARTRGASTVTMQLAGLLGDDARRSGQRSLPQKAGQALDALWLERTW CCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHCCHHHHCCHHCCHHHHHHHHHHHHHHHHC RKDQILEAYLNLVPFRGEAVGLSALSYTLFGKAPSGLDERESAVAAALIRAPNAPYPKVA CHHHHHHHHHHHCCCCCCEECHHHHEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHH ERACRILRDMQAAPRCAGLDGFVQLAFARPATPSSAFLDGEALAPHFARRVAAQVRPQAG HHHHHHHHHHHCCCCCCCCHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC ARVRSTLDAGLQRFTRDTLTRTLIELNAPPQSRDVQDGAAVVIDNRSGEILAWVGSSGAL HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCH SAAREVDAVLALRQAGSTLKPFLYAQAIDERRVTGATLLDDSPVDLAAGGGLYVPQNYDH HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCEECCCCEECCCCCCC DFKGWVSVRSALGSSLNVPAVRTLVLVTPHRFSKTLTALGLPLTEQGDYYGYSLALGSAD CHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCC VSLLTLANAYRALANGGVARPTFDLPRSTAPGAAPRPAPAGRRVFSADASFIVTDMLADN CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEHHHCCC NARTRTFGFDSPLATHAFSAVKTGTSKDMRDNWAVGFTSRYTVGVWVGNADGAPMRNVSG CCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEEEECCCCCCCCCCCC VTGAAPVWAAIVARLHRDGGSVAPTAPPGVVRERVSFERAIEPTRDEWFLRGTETTEVRL CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEE AAGAGGEPAAPAASRARPAGHVRTVSAGTAGLAPRAPLAIAAPTDGTIFAVDPDIPPRNQ EECCCCCCCCCCHHCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCC RVWFERVAGNSGRGSWRLDGRVIGHGERVAWLPWPGRHTLELLDADGKVADHVAFEVRGA EEEEEECCCCCCCCCEEECCEEEECCCEEEEECCCCCCEEEEECCCCCHHHHHHEEECCC VAKPGAAAGAAARAR CCCCCCCCCCHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10542235; 9205837; 9278503; 9841666 [H]