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The map label for this gene is estB [H]

Identifier: 238024600

GI number: 238024600

Start: 1549949

End: 1551115

Strand: Reverse

Name: estB [H]

Synonym: bglu_2g12150

Alternate gene names: 238024600

Gene position: 1551115-1549949 (Counterclockwise)

Preceding gene: 238024603

Following gene: 238024599

Centisome position: 54.86

GC content: 73.18

Gene sequence:

>1167_bases
ATGACGCAGACTTCGCCCGCCTCGATCGATCCCGTTGCCCTGTCGGCCCGCCTCGACGCCGTAGTCGAGCGCGCGCTGCG
CGAGCGCCGCGTGGTGGGCGCGGTGGGCATCGTCGCGCAGCACGGCAAGCTGCTGTACCGGCGCGCGCACGGCCTGGCCG
ACCGCGAGGCGCACCGGCCGATGCGCGAGGACACGCTGTTCCGCCTGGCCTCGGTGACCAAGCCGATCGTCGCGCTCGCG
GCGCTGCGGCTCGTGGCGAGCAAGGCGCTGGCGCTCGACGCGCCCGTCACGCGCTGGCTGCCCGGGTTCCGGCCGAAGCT
CGAGAACGGCGAGGCGCCCGAGATGACGATCCACCATCTGCTCACGCATACGGCCGGCCTCGGCTACTGGCTGCTCGACG
GGCCGGGCTCGCTATACGACCGGCTCGGTATTTCCGACGGGCTCGATCTTTGCGACTTCGGCCTCGACGAGAATCTGCGG
CGGCTGGCCGAGGCGCCGCTGGCGTTCGCGCCGGGCACCGGCTGGCAGTATTCGCTCGCGCTCGACGTGCTCGGCGCGGT
GATCGAGCGTGCTACCGGAACGACGCTGGCGCAGGCGGTGGCGACGCTGGTGGGCGAGCCGCTCGGGCTGCGTGACAGCG
GGTTCGTGTCGAACCAGCCCGAGCGGTTCGCGACGCCGTACTACGGCGGCAGCCCGGAGCCGGTGCGGATGGCCGACGGC
GTGGACGTGCCGATGCCCGAAGGGCAGGGCGCGGCGGTGCGCTTCGCGCCGTCGCGCGTGTTCGAGCCGGGCGCGTATCC
GTCCGGCGGCGCGGGGATGTACGGCTGCGCCGACGACGTGCTGCGGGTGCTGGAGGCGATTCGCGACGGCGGGCGCTTTC
TGCCCGACGCGCTTGCCGAGGCGGCGCGGCGCGATCAGGTGGGCGCCGCGGCCGAGACGCGCGGGCCGGGCTGGGGCTTT
GGCTATCTCGGGGCGGTGCTGAGCGATCCCGCGCTGGCGCAGACGCGGATGGCGGCCGGCACGCTGGCCTGGGGCGGGGT
GTACGGCCACTCGTGGTTCGTCGATCCGGCGTGGGGGCTGAGCGTGCTGCTGCTGACCAATACCGCCTATGAGGGGATGT
CGGGGGCATTGAAGATCGAGTTCGGCGAGGCCGTTTATGCGGGGTGA

Upstream 100 bases:

>100_bases
GGCAGGCGCGCGGGCGCGAGCGATCCATCAAAATCGGACCGTGGCGGGCATGGGGCTGATCTGTTTAGAATCGAGACTTT
CCCGTTGCGAGACCCTTGCC

Downstream 100 bases:

>100_bases
GCGGGGCAGGGCGCTGTCGCGTTGGCGGAGTATGTCCGCAAGCGGTGCGAGCGCAACCTGCATGTTTCATGCCGCAGACG
GATTCTGGGTGGCCTCGGGC

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTQTSPASIDPVALSARLDAVVERALRERRVVGAVGIVAQHGKLLYRRAHGLADREAHRPMREDTLFRLASVTKPIVALA
ALRLVASKALALDAPVTRWLPGFRPKLENGEAPEMTIHHLLTHTAGLGYWLLDGPGSLYDRLGISDGLDLCDFGLDENLR
RLAEAPLAFAPGTGWQYSLALDVLGAVIERATGTTLAQAVATLVGEPLGLRDSGFVSNQPERFATPYYGGSPEPVRMADG
VDVPMPEGQGAAVRFAPSRVFEPGAYPSGGAGMYGCADDVLRVLEAIRDGGRFLPDALAEAARRDQVGAAAETRGPGWGF
GYLGAVLSDPALAQTRMAAGTLAWGGVYGHSWFVDPAWGLSVLLLTNTAYEGMSGALKIEFGEAVYAG

Sequences:

>Translated_388_residues
MTQTSPASIDPVALSARLDAVVERALRERRVVGAVGIVAQHGKLLYRRAHGLADREAHRPMREDTLFRLASVTKPIVALA
ALRLVASKALALDAPVTRWLPGFRPKLENGEAPEMTIHHLLTHTAGLGYWLLDGPGSLYDRLGISDGLDLCDFGLDENLR
RLAEAPLAFAPGTGWQYSLALDVLGAVIERATGTTLAQAVATLVGEPLGLRDSGFVSNQPERFATPYYGGSPEPVRMADG
VDVPMPEGQGAAVRFAPSRVFEPGAYPSGGAGMYGCADDVLRVLEAIRDGGRFLPDALAEAARRDQVGAAAETRGPGWGF
GYLGAVLSDPALAQTRMAAGTLAWGGVYGHSWFVDPAWGLSVLLLTNTAYEGMSGALKIEFGEAVYAG
>Mature_387_residues
TQTSPASIDPVALSARLDAVVERALRERRVVGAVGIVAQHGKLLYRRAHGLADREAHRPMREDTLFRLASVTKPIVALAA
LRLVASKALALDAPVTRWLPGFRPKLENGEAPEMTIHHLLTHTAGLGYWLLDGPGSLYDRLGISDGLDLCDFGLDENLRR
LAEAPLAFAPGTGWQYSLALDVLGAVIERATGTTLAQAVATLVGEPLGLRDSGFVSNQPERFATPYYGGSPEPVRMADGV
DVPMPEGQGAAVRFAPSRVFEPGAYPSGGAGMYGCADDVLRVLEAIRDGGRFLPDALAEAARRDQVGAAAETRGPGWGFG
YLGAVLSDPALAQTRMAAGTLAWGGVYGHSWFVDPAWGLSVLLLTNTAYEGMSGALKIEFGEAVYAG

Specific function: Acts on short-chain (C4-C6) fatty acid esters and triglycerides, including tertiary alcohol esters. Activity on p- nitrophenyl esters is generally higher than on o-nitrophenyl esters. Lacks beta-lactamase activity; it hydrolyzes the ester bond of cephalos

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-A beta-lactamase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI115533026, Length=202, Percent_Identity=26.7326732673267, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR000871 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 41087; Mature: 40956

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTSPASIDPVALSARLDAVVERALRERRVVGAVGIVAQHGKLLYRRAHGLADREAHRP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
MREDTLFRLASVTKPIVALAALRLVASKALALDAPVTRWLPGFRPKLENGEAPEMTIHHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHHHHHHH
LTHTAGLGYWLLDGPGSLYDRLGISDGLDLCDFGLDENLRRLAEAPLAFAPGTGWQYSLA
HHHHCCCCEEEECCCHHHHHHCCCCCCCHHHHCCCCHHHHHHHHCCCEECCCCCCCHHHH
LDVLGAVIERATGTTLAQAVATLVGEPLGLRDSGFVSNQPERFATPYYGGSPEPVRMADG
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCEEECCC
VDVPMPEGQGAAVRFAPSRVFEPGAYPSGGAGMYGCADDVLRVLEAIRDGGRFLPDALAE
CCCCCCCCCCCEEEECHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
AARRDQVGAAAETRGPGWGFGYLGAVLSDPALAQTRMAAGTLAWGGVYGHSWFVDPAWGL
HHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHEECCCCCCCEECCCCCCC
SVLLLTNTAYEGMSGALKIEFGEAVYAG
EEEEEECCHHCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
TQTSPASIDPVALSARLDAVVERALRERRVVGAVGIVAQHGKLLYRRAHGLADREAHRP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
MREDTLFRLASVTKPIVALAALRLVASKALALDAPVTRWLPGFRPKLENGEAPEMTIHHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHHHHHHH
LTHTAGLGYWLLDGPGSLYDRLGISDGLDLCDFGLDENLRRLAEAPLAFAPGTGWQYSLA
HHHHCCCCEEEECCCHHHHHHCCCCCCCHHHHCCCCHHHHHHHHCCCEECCCCCCCHHHH
LDVLGAVIERATGTTLAQAVATLVGEPLGLRDSGFVSNQPERFATPYYGGSPEPVRMADG
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCEEECCC
VDVPMPEGQGAAVRFAPSRVFEPGAYPSGGAGMYGCADDVLRVLEAIRDGGRFLPDALAE
CCCCCCCCCCCEEEECHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
AARRDQVGAAAETRGPGWGFGYLGAVLSDPALAQTRMAAGTLAWGGVYGHSWFVDPAWGL
HHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHEECCCCCCCEECCCCCCC
SVLLLTNTAYEGMSGALKIEFGEAVYAG
EEEEEECCHHCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11472796; 11847270 [H]