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The map label for this gene is ycbL [H]

Identifier: 229918248

GI number: 229918248

Start: 2490838

End: 2492238

Strand: Reverse

Name: ycbL [H]

Synonym: EAT1b_2529

Alternate gene names: 229918248

Gene position: 2492238-2490838 (Counterclockwise)

Preceding gene: 229918249

Following gene: 229918247

Centisome position: 83.08

GC content: 51.18

Gene sequence:

>1401_bases
ATGCTATTACGTTATTTTTATGATGAAAAATTAGCACAAGCTTCATATATAGTCGGTTGCCAAATGACGGGAGAAGCCAT
CGTCATCGACCCGGCCCGTAACATCGAACCTTATCTTCAAGAAGCGAAAAAAGAAGGCATGAACATCGTCGCAACGGCAG
AGACGCATATCCATGCAGACTTTGTGTCCGGTTCACTCGAACTTGCGAAGCGCACAGGTTCGAAAGCCTATCTATCAGAC
GAAGGTGATGCTTCTTGGAAGTATACATTCGCGAAAGAAATCGACGCACAACTCGTCAAAGAAGGCGACACGTTCAAAAT
CGGAAACGTGACACTTGAAGTCATGCACACACCGGGTCACACACCGGAACATATCTCGTTCCTCCTGTATGACCGGAACC
AGACACAACCGATGGGGATCTTCACAGGCGATTTCGTCTTCGTCGGGGATATCGGTCGCCCCGACCTTCTCGAAGAAGCA
GCCGGTGTGAAAGGAACGACGGCAATCGGCGCGGAACAAATGTTTGATTCACTCAAAAAGTTCATGGCGCTTCCTGACTT
CGTTCAAGTTTGGCCAGGACACGGTGCCGGCAGCGCTTGTGGGAAAGCGCTCGGCGCGATCCCAACATCGACGGTCGGTT
ACGAGAAAGCGACGAACTGGGCGCTTCAAATGACGGATAAAGATGCCTTCATCAAAGAGTTGACGACGGATCAACCCGAA
CCACCGAACTACTTTGCCATGATGAAAAAAGTAAACAAAGAAGGTATCCAAGTGACGACGGAAGTCGCTCGTCCTGAAGT
CGTCGGGTCGGACCGTCTCGATACACTCGTCGAAGAGACGCAAGTCATCGACACGCGTAAAGGAGAAGACTTTGCGAACG
GACACGTACCAGGGACAATCAACATCCCGTACAACAACAAGTTCGTCTCGTGGGCTGGCTGGCTCGTCAACTTCGACAAA
GACATCACACTTATCGCAAGTGCGGATGACGTCGATCAAGTGCAGACCGACCTTCAATCCATCGGTCTCGATCGCCTTCG
CTTCATCGTCCCAGTCGAAGAGCTCGACGCATCACTTTTGACGGAAACGTATACGGACGTGACGGCAGAAGAAGCAATCG
AAGCTGCTGAAAAAGGTGACGTCTTCGTCCTCGACGTTCGAAACGCGACAGAATGGAACGCGAGCCATTACGAAAAGGCA
GAGCGCATCTTGCTCGGTAAGCTCGCACGTGATCACGAAGGTCTACCGACAGATCAAACGATTGCGGTTCATTGTGCATC
AGGCGTCCGCTCACGCATGGCGGCAAGTGTCCTTCAATCGCTCGGCTACAAAGATATCCACAATATCCTCGGTGGCTACG
GCGCGATGAAGACTGTCTTGAACGCTCAACAGATCAAGTAA

Upstream 100 bases:

>100_bases
CTCGATTCACTCGGATTCGATGTCACGAACGTCGACGGTGGAATGATGAGCTGGCAAGGCGAAGTCGAATAAACGATTAC
ATCCATAGGGGGAAATTGAT

Downstream 100 bases:

>100_bases
TGCTATACTGACCATAAATATGGCGCCCGCTTCGAGAGGGGCGCCTTTTGTTTAGGAGGGAAAGACGTGGTCGCCATCGG
TCCACTCAACATTCGTTTCG

Product: beta-lactamase domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MLLRYFYDEKLAQASYIVGCQMTGEAIVIDPARNIEPYLQEAKKEGMNIVATAETHIHADFVSGSLELAKRTGSKAYLSD
EGDASWKYTFAKEIDAQLVKEGDTFKIGNVTLEVMHTPGHTPEHISFLLYDRNQTQPMGIFTGDFVFVGDIGRPDLLEEA
AGVKGTTAIGAEQMFDSLKKFMALPDFVQVWPGHGAGSACGKALGAIPTSTVGYEKATNWALQMTDKDAFIKELTTDQPE
PPNYFAMMKKVNKEGIQVTTEVARPEVVGSDRLDTLVEETQVIDTRKGEDFANGHVPGTINIPYNNKFVSWAGWLVNFDK
DITLIASADDVDQVQTDLQSIGLDRLRFIVPVEELDASLLTETYTDVTAEEAIEAAEKGDVFVLDVRNATEWNASHYEKA
ERILLGKLARDHEGLPTDQTIAVHCASGVRSRMAASVLQSLGYKDIHNILGGYGAMKTVLNAQQIK

Sequences:

>Translated_466_residues
MLLRYFYDEKLAQASYIVGCQMTGEAIVIDPARNIEPYLQEAKKEGMNIVATAETHIHADFVSGSLELAKRTGSKAYLSD
EGDASWKYTFAKEIDAQLVKEGDTFKIGNVTLEVMHTPGHTPEHISFLLYDRNQTQPMGIFTGDFVFVGDIGRPDLLEEA
AGVKGTTAIGAEQMFDSLKKFMALPDFVQVWPGHGAGSACGKALGAIPTSTVGYEKATNWALQMTDKDAFIKELTTDQPE
PPNYFAMMKKVNKEGIQVTTEVARPEVVGSDRLDTLVEETQVIDTRKGEDFANGHVPGTINIPYNNKFVSWAGWLVNFDK
DITLIASADDVDQVQTDLQSIGLDRLRFIVPVEELDASLLTETYTDVTAEEAIEAAEKGDVFVLDVRNATEWNASHYEKA
ERILLGKLARDHEGLPTDQTIAVHCASGVRSRMAASVLQSLGYKDIHNILGGYGAMKTVLNAQQIK
>Mature_466_residues
MLLRYFYDEKLAQASYIVGCQMTGEAIVIDPARNIEPYLQEAKKEGMNIVATAETHIHADFVSGSLELAKRTGSKAYLSD
EGDASWKYTFAKEIDAQLVKEGDTFKIGNVTLEVMHTPGHTPEHISFLLYDRNQTQPMGIFTGDFVFVGDIGRPDLLEEA
AGVKGTTAIGAEQMFDSLKKFMALPDFVQVWPGHGAGSACGKALGAIPTSTVGYEKATNWALQMTDKDAFIKELTTDQPE
PPNYFAMMKKVNKEGIQVTTEVARPEVVGSDRLDTLVEETQVIDTRKGEDFANGHVPGTINIPYNNKFVSWAGWLVNFDK
DITLIASADDVDQVQTDLQSIGLDRLRFIVPVEELDASLLTETYTDVTAEEAIEAAEKGDVFVLDVRNATEWNASHYEKA
ERILLGKLARDHEGLPTDQTIAVHCASGVRSRMAASVLQSLGYKDIHNILGGYGAMKTVLNAQQIK

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=264, Percent_Identity=24.6212121212121, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI14150041, Length=183, Percent_Identity=28.9617486338798, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI46361987, Length=183, Percent_Identity=29.5081967213115, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI116642887, Length=209, Percent_Identity=25.8373205741627, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI21703352, Length=209, Percent_Identity=25.8373205741627, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787158, Length=226, Percent_Identity=32.3008849557522, Blast_Score=98, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17538952, Length=246, Percent_Identity=27.6422764227642, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221330176, Length=202, Percent_Identity=24.7524752475248, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 51222; Mature: 51222

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLRYFYDEKLAQASYIVGCQMTGEAIVIDPARNIEPYLQEAKKEGMNIVATAETHIHAD
CEEEEHHHHHHHHHHEEEEEEECCCEEEECCCCCCCHHHHHHHHCCCEEEEEECCEEEEH
FVSGSLELAKRTGSKAYLSDEGDASWKYTFAKEIDAQLVKEGDTFKIGNVTLEVMHTPGH
HHCCHHHHHHHCCCCEEECCCCCCCEEEEHHHHHHHHHHCCCCCEEECCEEEEEEECCCC
TPEHISFLLYDRNQTQPMGIFTGDFVFVGDIGRPDLLEEAAGVKGTTAIGAEQMFDSLKK
CCCCEEEEEEECCCCCCCEEEECCEEEEECCCCCHHHHHHCCCCCCHHCCHHHHHHHHHH
FMALPDFVQVWPGHGAGSACGKALGAIPTSTVGYEKATNWALQMTDKDAFIKELTTDQPE
HHCCCCHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCC
PPNYFAMMKKVNKEGIQVTTEVARPEVVGSDRLDTLVEETQVIDTRKGEDFANGHVPGTI
CCHHHHHHHHHCCCCCEEEEHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
NIPYNNKFVSWAGWLVNFDKDITLIASADDVDQVQTDLQSIGLDRLRFIVPVEELDASLL
ECCCCCCEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHH
TETYTDVTAEEAIEAAEKGDVFVLDVRNATEWNASHYEKAERILLGKLARDHEGLPTDQT
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCE
IAVHCASGVRSRMAASVLQSLGYKDIHNILGGYGAMKTVLNAQQIK
EEEEEHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLRYFYDEKLAQASYIVGCQMTGEAIVIDPARNIEPYLQEAKKEGMNIVATAETHIHAD
CEEEEHHHHHHHHHHEEEEEEECCCEEEECCCCCCCHHHHHHHHCCCEEEEEECCEEEEH
FVSGSLELAKRTGSKAYLSDEGDASWKYTFAKEIDAQLVKEGDTFKIGNVTLEVMHTPGH
HHCCHHHHHHHCCCCEEECCCCCCCEEEEHHHHHHHHHHCCCCCEEECCEEEEEEECCCC
TPEHISFLLYDRNQTQPMGIFTGDFVFVGDIGRPDLLEEAAGVKGTTAIGAEQMFDSLKK
CCCCEEEEEEECCCCCCCEEEECCEEEEECCCCCHHHHHHCCCCCCHHCCHHHHHHHHHH
FMALPDFVQVWPGHGAGSACGKALGAIPTSTVGYEKATNWALQMTDKDAFIKELTTDQPE
HHCCCCHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCC
PPNYFAMMKKVNKEGIQVTTEVARPEVVGSDRLDTLVEETQVIDTRKGEDFANGHVPGTI
CCHHHHHHHHHCCCCCEEEEHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
NIPYNNKFVSWAGWLVNFDKDITLIASADDVDQVQTDLQSIGLDRLRFIVPVEELDASLL
ECCCCCCEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHH
TETYTDVTAEEAIEAAEKGDVFVLDVRNATEWNASHYEKAERILLGKLARDHEGLPTDQT
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCE
IAVHCASGVRSRMAASVLQSLGYKDIHNILGGYGAMKTVLNAQQIK
EEEEEHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]