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The map label for this gene is nhaC [H]

Identifier: 229917755

GI number: 229917755

Start: 1985013

End: 1986296

Strand: Reverse

Name: nhaC [H]

Synonym: EAT1b_2033

Alternate gene names: 229917755

Gene position: 1986296-1985013 (Counterclockwise)

Preceding gene: 229917756

Following gene: 229917753

Centisome position: 66.21

GC content: 53.12

Gene sequence:

>1284_bases
TTGGAACAACCAACAGCAAACAAATGGGCACTCTTGCCGTTACTCGTCTTCTTACTCTTCTTCATCGGAGCGGGTGTCTA
TTACGGAGACTTCTATAAGTTTCCGGTACTCGTTGCGGCCATCATCGCCTTGATGGTTGCGGCATTCATGACAAAAGGAA
GTGCCACCCAAACCGTCGAGCGCATCGCGCAAGGAGCCGGGAACCCGGGCATCATCATCATGATTTTCATTTTCTTACTG
GCTGGCGCCTTTTCAACGGTAGCGGAAGCCATCGGGGCAATCGATGCAACGGTCAACGCCGCCTTGACTCTATTACCACC
ATCGCTTCTCTTGAGCGGACTCTTCGTCATCGCCGCTTTCATTTCAATGGCGATGGGCACATCGACCGGGACGATTGCGG
CACTTGCACCAATCGCCCTCGGTATCCATGAAGAGAGCGGCGTCAATGTCGCCATCGCTGCCGCAGCCGTTGTCGGAGGA
GCAATGTTCGGGGACAATCTCTCGTTCATCTCGGACACGACGATCGCTGCCGTCCGGACGCAACGAACGAACATGCGTGA
TAAATTCCGCACGAACTTCTGGATCGTGCTACCGGCCGCCATCATCACGACGATTTTACTCGCCGTCTTGTCAAATGGGG
AGTCCACGGTCGATGTCGCCGCATTCGAATGGTACAAACTGATTCCGTATCTTGCCGTCATCGGACTCGCATTGACAGGA
TTGAACGTCATCTTGGTTCTGTTAGGTGGTATCACGCTCACCGGTATCATCGGTCTCCTGGATGGAAGCCTATCCGTCAC
AGCGTTTGTGACAGCCATTGCGGACGGGATGATTGGCATGGCCGAAATTTCATTCCTGACGTTACTCATGGGTGGACTCG
TCGGTCTCATCTCACACAACGGCGGACTCACGTATTTACGTGACGCGTTGACATCTCGTATTCAAAAACGTGCCGGTGCC
GAGTGGAGTATCGCTGGTCTCGTCAGTGCGACGAACGTAGCGACGGCGAACAATACGATTTCCATTCTCGTAGCCGGACC
GCTTGCAGCGAACATCGCGGACGAGTATGACATCGAACGGAAGAAATCAGCGAGCGTACTCGATATCTTCTCATGTGGCG
TACAAGGAATTCTCCCATATGGAGCACAACTTCTCATCGCCGCAGAGTTGACGAAGACCGCTTCGCCGGACCTCGTCCCG
TTCATGTTCTATCCGTTCCTCCTCTTTATTTGTGGAGGAATCGCCATCGCATTCAATTTCCCGCGTTTCAAAAAACAGTC
ATAA

Upstream 100 bases:

>100_bases
AATCCAGCGGGCGTATTGCTCGAAAGATGAAAAGGGTATTTCGCACGAAGGACCTTTTTCTTAAGAAAGGGTCCTTTTTA
TTTTTAGTGAGGTGATTATT

Downstream 100 bases:

>100_bases
CCAAAAACACCCCTTGTTCAAAGGGGTGTTTGTCGTTTGGTTATCATTTCTTGTTTCAACTGCTCGTTGCGTTTCTTGAA
CGCCCGTCGTTTGAGCACTT

Product: Na+/H+ antiporter NhaC

Products: NA

Alternate protein names: Sodium/hydrogen antiporter; Sodium/proton antiporter [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MEQPTANKWALLPLLVFLLFFIGAGVYYGDFYKFPVLVAAIIALMVAAFMTKGSATQTVERIAQGAGNPGIIIMIFIFLL
AGAFSTVAEAIGAIDATVNAALTLLPPSLLLSGLFVIAAFISMAMGTSTGTIAALAPIALGIHEESGVNVAIAAAAVVGG
AMFGDNLSFISDTTIAAVRTQRTNMRDKFRTNFWIVLPAAIITTILLAVLSNGESTVDVAAFEWYKLIPYLAVIGLALTG
LNVILVLLGGITLTGIIGLLDGSLSVTAFVTAIADGMIGMAEISFLTLLMGGLVGLISHNGGLTYLRDALTSRIQKRAGA
EWSIAGLVSATNVATANNTISILVAGPLAANIADEYDIERKKSASVLDIFSCGVQGILPYGAQLLIAAELTKTASPDLVP
FMFYPFLLFICGGIAIAFNFPRFKKQS

Sequences:

>Translated_427_residues
MEQPTANKWALLPLLVFLLFFIGAGVYYGDFYKFPVLVAAIIALMVAAFMTKGSATQTVERIAQGAGNPGIIIMIFIFLL
AGAFSTVAEAIGAIDATVNAALTLLPPSLLLSGLFVIAAFISMAMGTSTGTIAALAPIALGIHEESGVNVAIAAAAVVGG
AMFGDNLSFISDTTIAAVRTQRTNMRDKFRTNFWIVLPAAIITTILLAVLSNGESTVDVAAFEWYKLIPYLAVIGLALTG
LNVILVLLGGITLTGIIGLLDGSLSVTAFVTAIADGMIGMAEISFLTLLMGGLVGLISHNGGLTYLRDALTSRIQKRAGA
EWSIAGLVSATNVATANNTISILVAGPLAANIADEYDIERKKSASVLDIFSCGVQGILPYGAQLLIAAELTKTASPDLVP
FMFYPFLLFICGGIAIAFNFPRFKKQS
>Mature_427_residues
MEQPTANKWALLPLLVFLLFFIGAGVYYGDFYKFPVLVAAIIALMVAAFMTKGSATQTVERIAQGAGNPGIIIMIFIFLL
AGAFSTVAEAIGAIDATVNAALTLLPPSLLLSGLFVIAAFISMAMGTSTGTIAALAPIALGIHEESGVNVAIAAAAVVGG
AMFGDNLSFISDTTIAAVRTQRTNMRDKFRTNFWIVLPAAIITTILLAVLSNGESTVDVAAFEWYKLIPYLAVIGLALTG
LNVILVLLGGITLTGIIGLLDGSLSVTAFVTAIADGMIGMAEISFLTLLMGGLVGLISHNGGLTYLRDALTSRIQKRAGA
EWSIAGLVSATNVATANNTISILVAGPLAANIADEYDIERKKSASVLDIFSCGVQGILPYGAQLLIAAELTKTASPDLVP
FMFYPFLLFICGGIAIAFNFPRFKKQS

Specific function: Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion [H]

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004770
- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 44598; Mature: 44598

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQPTANKWALLPLLVFLLFFIGAGVYYGDFYKFPVLVAAIIALMVAAFMTKGSATQTVE
CCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RIAQGAGNPGIIIMIFIFLLAGAFSTVAEAIGAIDATVNAALTLLPPSLLLSGLFVIAAF
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ISMAMGTSTGTIAALAPIALGIHEESGVNVAIAAAAVVGGAMFGDNLSFISDTTIAAVRT
HHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCHHHHHHH
QRTNMRDKFRTNFWIVLPAAIITTILLAVLSNGESTVDVAAFEWYKLIPYLAVIGLALTG
HHCCCHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
LNVILVLLGGITLTGIIGLLDGSLSVTAFVTAIADGMIGMAEISFLTLLMGGLVGLISHN
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
GGLTYLRDALTSRIQKRAGAEWSIAGLVSATNVATANNTISILVAGPLAANIADEYDIER
CCHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCEEECCCEEEEEEECCHHHHCCHHHCCCH
KKSASVLDIFSCGVQGILPYGAQLLIAAELTKTASPDLVPFMFYPFLLFICGGIAIAFNF
HCCCCHHHHHHCCHHHHCCCCHHEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEECC
PRFKKQS
CCCCCCC
>Mature Secondary Structure
MEQPTANKWALLPLLVFLLFFIGAGVYYGDFYKFPVLVAAIIALMVAAFMTKGSATQTVE
CCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RIAQGAGNPGIIIMIFIFLLAGAFSTVAEAIGAIDATVNAALTLLPPSLLLSGLFVIAAF
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ISMAMGTSTGTIAALAPIALGIHEESGVNVAIAAAAVVGGAMFGDNLSFISDTTIAAVRT
HHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCHHHHHHH
QRTNMRDKFRTNFWIVLPAAIITTILLAVLSNGESTVDVAAFEWYKLIPYLAVIGLALTG
HHCCCHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
LNVILVLLGGITLTGIIGLLDGSLSVTAFVTAIADGMIGMAEISFLTLLMGGLVGLISHN
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
GGLTYLRDALTSRIQKRAGAEWSIAGLVSATNVATANNTISILVAGPLAANIADEYDIER
CCHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCEEECCCEEEEEEECCHHHHCCHHHCCCH
KKSASVLDIFSCGVQGILPYGAQLLIAAELTKTASPDLVPFMFYPFLLFICGGIAIAFNF
HCCCCHHHHHHCCHHHHCCCCHHEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEECC
PRFKKQS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1660475; 9190799 [H]