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The map label for this gene is aidB [H]

Identifier: 227826884

GI number: 227826884

Start: 456793

End: 458433

Strand: Direct

Name: aidB [H]

Synonym: M1425_0516

Alternate gene names: 227826884

Gene position: 456793-458433 (Clockwise)

Preceding gene: 227826881

Following gene: 227826885

Centisome position: 17.51

GC content: 37.29

Gene sequence:

>1641_bases
ATGAGTAAGGGTAATAGTCCTTTCTCATATATATCTAGTGCGTATGGGAAAAATCATTTTAATATTGATAAACCATTACA
AAAGATTTTGGAATATTTTGATGTGAAAGCAGACTTCTCAAAATTAGGTGAGTTTGCAGGGGGAGAATTATATGAAATTG
CGGAACATGTAGATAAGAGAGCTAGACCCATACACGTAATGTGGAGCGTAAATGGGGAGAGAGTAGATGAAGTATGGATT
GATCCTTCTCTAAGGGCAGCTATTAAAAGGCTAATCAAAGATTTCGATATTAATAAATTTCCATATAAAGAGGAAAATTG
GCATAAGCACTACGCTTCAATATATCTAGTTTCTGATCCAGGTATAGCATGCATACTTACAATTACCAATCAGACCGCAT
ACGCTCTCTATAAATACGGTAGCGAGGAACTAAAGAAATACGTTCCCTATCTAATAGGAGATTCAGATGAGTTGCTTTTC
GGAGCTACGTGGTTCACTGAGATTCAAGGTGGAAGTGACTTAGGATCTAATTTAGTGGAGGCTGAATTTAACGGTAAGTA
TTGGCTATTAAAAGGAAATACTAAATATTTCGCTAGCGGTGTCGGGTTGGCTGATTTAGCGTTAGTAAGTGCTAGACCTA
TGGGAAGTAAGAGTGGGGCTAAAGGCCTTTCCCTATTCCTAGTTCCTAAAAAGAACAATAAAGGTGAAAAGAATTTTTTG
ATAAGAAGACTTAAGAGAAAAAGTGGAACAAATAGTGTGCCAACTGGAGAGGTGGAGTTTAACAGTTCAGAGGCTTATCT
TATAGGAGAAAAGGAATATGGGATATATTACATAACTGAGGATCTTATGGTATCAAGATTATCCAATGCTGTAGGGGCTT
TAGGTATAGCGAGGAAGTCTTTTCTCGAATCCTATTATTATTCGCAATCCAGAAAAGCTTTTGGTAAGGCATTAATTGAA
CATCCCCTAATTCAGAAAGATTTACTTGAAATGGAGCTCATGATTGAAGGAGGTATGGTAGTAACTTTTAAGGCAATAGA
TCAGTTCCAAAAATCTTGGAAAGCTATGCCACCTTTCTACAATGAGCAGTACCATTATGCGCGTCTATTGACTCATATTT
CTAAGCATATTACAGCTGAAATAGCATCTCAAGTATCAAGAATGGCAATGGAGATTCATGGAGGAATTGGATTTCTCGAA
GAGTTTCCTATAGAAAGACTTCACAGAGAAGCGCTTATAACTCCAATTTGGGAAGGGACTGGAAACATTCAGGCTTTAGA
GATGCTCGAAGCCATGGTGAAGAAGGAAGCACATAGACAACTAATAAGGGACTTGGAAGGGATTGTAAATGAAGCAAAGG
ATGAGATAGCTTCCAAAACGCTTGATTTCATCAAAGATAAGGCCACCACGCTCCTAACTTACAGAGAATATGAGATGCAG
TTTTACTCAAAAGATTTACTATTAACTTTAGGGCATGGTATTTCCGTGATATTACTATCCCATATGGGCCGTAAGTTGGG
TATTGAGCGATTCACAATGTTGTCGAAGATCTACTATGAGAGATTTCTAATGGGTAGAAGCATTCTACGAGATTATATAT
CTGAAATACGTGAGCTTATAAATATAGAAGAGATGAAATAG

Upstream 100 bases:

>100_bases
TATTTTTAAGAAGTAATTTTTGGGTCTACCATGAGGGTGAGGTAATCCACATTCCTAAAGTACTATACGCTTATAAGTTG
TATAAGAATAAATATAGACT

Downstream 100 bases:

>100_bases
AGGTTTTAGAAATGCAAGAGGGTTTTACCGTATTCTCGCTTCTTAAAAGGGCAGTAACTATAGCGCCAGATAAGGAAATA
GTAGATCCTTTTCGCAATGT

Product: acyl-CoA dehydrogenase domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MSKGNSPFSYISSAYGKNHFNIDKPLQKILEYFDVKADFSKLGEFAGGELYEIAEHVDKRARPIHVMWSVNGERVDEVWI
DPSLRAAIKRLIKDFDINKFPYKEENWHKHYASIYLVSDPGIACILTITNQTAYALYKYGSEELKKYVPYLIGDSDELLF
GATWFTEIQGGSDLGSNLVEAEFNGKYWLLKGNTKYFASGVGLADLALVSARPMGSKSGAKGLSLFLVPKKNNKGEKNFL
IRRLKRKSGTNSVPTGEVEFNSSEAYLIGEKEYGIYYITEDLMVSRLSNAVGALGIARKSFLESYYYSQSRKAFGKALIE
HPLIQKDLLEMELMIEGGMVVTFKAIDQFQKSWKAMPPFYNEQYHYARLLTHISKHITAEIASQVSRMAMEIHGGIGFLE
EFPIERLHREALITPIWEGTGNIQALEMLEAMVKKEAHRQLIRDLEGIVNEAKDEIASKTLDFIKDKATTLLTYREYEMQ
FYSKDLLLTLGHGISVILLSHMGRKLGIERFTMLSKIYYERFLMGRSILRDYISEIRELINIEEMK

Sequences:

>Translated_546_residues
MSKGNSPFSYISSAYGKNHFNIDKPLQKILEYFDVKADFSKLGEFAGGELYEIAEHVDKRARPIHVMWSVNGERVDEVWI
DPSLRAAIKRLIKDFDINKFPYKEENWHKHYASIYLVSDPGIACILTITNQTAYALYKYGSEELKKYVPYLIGDSDELLF
GATWFTEIQGGSDLGSNLVEAEFNGKYWLLKGNTKYFASGVGLADLALVSARPMGSKSGAKGLSLFLVPKKNNKGEKNFL
IRRLKRKSGTNSVPTGEVEFNSSEAYLIGEKEYGIYYITEDLMVSRLSNAVGALGIARKSFLESYYYSQSRKAFGKALIE
HPLIQKDLLEMELMIEGGMVVTFKAIDQFQKSWKAMPPFYNEQYHYARLLTHISKHITAEIASQVSRMAMEIHGGIGFLE
EFPIERLHREALITPIWEGTGNIQALEMLEAMVKKEAHRQLIRDLEGIVNEAKDEIASKTLDFIKDKATTLLTYREYEMQ
FYSKDLLLTLGHGISVILLSHMGRKLGIERFTMLSKIYYERFLMGRSILRDYISEIRELINIEEMK
>Mature_545_residues
SKGNSPFSYISSAYGKNHFNIDKPLQKILEYFDVKADFSKLGEFAGGELYEIAEHVDKRARPIHVMWSVNGERVDEVWID
PSLRAAIKRLIKDFDINKFPYKEENWHKHYASIYLVSDPGIACILTITNQTAYALYKYGSEELKKYVPYLIGDSDELLFG
ATWFTEIQGGSDLGSNLVEAEFNGKYWLLKGNTKYFASGVGLADLALVSARPMGSKSGAKGLSLFLVPKKNNKGEKNFLI
RRLKRKSGTNSVPTGEVEFNSSEAYLIGEKEYGIYYITEDLMVSRLSNAVGALGIARKSFLESYYYSQSRKAFGKALIEH
PLIQKDLLEMELMIEGGMVVTFKAIDQFQKSWKAMPPFYNEQYHYARLLTHISKHITAEIASQVSRMAMEIHGGIGFLEE
FPIERLHREALITPIWEGTGNIQALEMLEAMVKKEAHRQLIRDLEGIVNEAKDEIASKTLDFIKDKATTLLTYREYEMQF
YSKDLLLTLGHGISVILLSHMGRKLGIERFTMLSKIYYERFLMGRSILRDYISEIRELINIEEMK

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=297, Percent_Identity=30.6397306397306, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI4557233, Length=296, Percent_Identity=30.0675675675676, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI4501859, Length=311, Percent_Identity=27.9742765273312, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI7656849, Length=302, Percent_Identity=26.4900662251656, Blast_Score=93, Evalue=8e-19,
Organism=Homo sapiens, GI187960098, Length=293, Percent_Identity=29.3515358361775, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4557231, Length=293, Percent_Identity=29.3515358361775, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI226958412, Length=306, Percent_Identity=27.7777777777778, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI226958414, Length=303, Percent_Identity=26.7326732673267, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI87082384, Length=392, Percent_Identity=28.3163265306122, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081958, Length=312, Percent_Identity=26.2820512820513, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI86563381, Length=441, Percent_Identity=29.0249433106576, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI86563383, Length=441, Percent_Identity=29.0249433106576, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17508101, Length=311, Percent_Identity=26.6881028938907, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=324, Percent_Identity=26.2345679012346, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=296, Percent_Identity=29.0540540540541, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17533517, Length=321, Percent_Identity=26.4797507788162, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538396, Length=314, Percent_Identity=28.9808917197452, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17534899, Length=299, Percent_Identity=26.4214046822742, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17570075, Length=324, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=210, Percent_Identity=31.4285714285714, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17505929, Length=321, Percent_Identity=24.9221183800623, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356377, Length=310, Percent_Identity=28.0645161290323, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24666513, Length=324, Percent_Identity=25.3086419753086, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24660351, Length=293, Percent_Identity=29.3515358361775, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24646207, Length=325, Percent_Identity=26.4615384615385, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 62382; Mature: 62250

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKGNSPFSYISSAYGKNHFNIDKPLQKILEYFDVKADFSKLGEFAGGELYEIAEHVDKR
CCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHC
ARPIHVMWSVNGERVDEVWIDPSLRAAIKRLIKDFDINKFPYKEENWHKHYASIYLVSDP
CCCEEEEEECCCCEEHHEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECC
GIACILTITNQTAYALYKYGSEELKKYVPYLIGDSDELLFGATWFTEIQGGSDLGSNLVE
CEEEEEEECCCCCHHHHHCCHHHHHHHCCEEECCCCCEEEEEEEHEEECCCCCCCCCCEE
AEFNGKYWLLKGNTKYFASGVGLADLALVSARPMGSKSGAKGLSLFLVPKKNNKGEKNFL
EEECCEEEEEECCCEEEECCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHH
IRRLKRKSGTNSVPTGEVEFNSSEAYLIGEKEYGIYYITEDLMVSRLSNAVGALGIARKS
HHHHHHHCCCCCCCCCEEEECCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
FLESYYYSQSRKAFGKALIEHPLIQKDLLEMELMIEGGMVVTFKAIDQFQKSWKAMPPFY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCEEEEHHHHHHHHHHHCCCCCCC
NEQYHYARLLTHISKHITAEIASQVSRMAMEIHGGIGFLEEFPIERLHREALITPIWEGT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCEECCC
GNIQALEMLEAMVKKEAHRQLIRDLEGIVNEAKDEIASKTLDFIKDKATTLLTYREYEMQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHH
FYSKDLLLTLGHGISVILLSHMGRKLGIERFTMLSKIYYERFLMGRSILRDYISEIRELI
HHHCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIEEMK
HHHCCC
>Mature Secondary Structure 
SKGNSPFSYISSAYGKNHFNIDKPLQKILEYFDVKADFSKLGEFAGGELYEIAEHVDKR
CCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHC
ARPIHVMWSVNGERVDEVWIDPSLRAAIKRLIKDFDINKFPYKEENWHKHYASIYLVSDP
CCCEEEEEECCCCEEHHEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECC
GIACILTITNQTAYALYKYGSEELKKYVPYLIGDSDELLFGATWFTEIQGGSDLGSNLVE
CEEEEEEECCCCCHHHHHCCHHHHHHHCCEEECCCCCEEEEEEEHEEECCCCCCCCCCEE
AEFNGKYWLLKGNTKYFASGVGLADLALVSARPMGSKSGAKGLSLFLVPKKNNKGEKNFL
EEECCEEEEEECCCEEEECCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHH
IRRLKRKSGTNSVPTGEVEFNSSEAYLIGEKEYGIYYITEDLMVSRLSNAVGALGIARKS
HHHHHHHCCCCCCCCCEEEECCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
FLESYYYSQSRKAFGKALIEHPLIQKDLLEMELMIEGGMVVTFKAIDQFQKSWKAMPPFY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCEEEEHHHHHHHHHHHCCCCCCC
NEQYHYARLLTHISKHITAEIASQVSRMAMEIHGGIGFLEEFPIERLHREALITPIWEGT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCEECCC
GNIQALEMLEAMVKKEAHRQLIRDLEGIVNEAKDEIASKTLDFIKDKATTLLTYREYEMQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHH
FYSKDLLLTLGHGISVILLSHMGRKLGIERFTMLSKIYYERFLMGRSILRDYISEIRELI
HHHCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIEEMK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]