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The map label for this gene is ribD [C]

Identifier: 227826855

GI number: 227826855

Start: 424920

End: 425555

Strand: Direct

Name: ribD [C]

Synonym: M1425_0481

Alternate gene names: 227826855

Gene position: 424920-425555 (Clockwise)

Preceding gene: 227826853

Following gene: 227826856

Centisome position: 16.29

GC content: 35.38

Gene sequence:

>636_bases
ATGAGACCTTATGTAATAATATTTAGCACGTTATCAATAGATGGTAGACTCGCAACGAAAACTGGTTATAGCGAATTAAG
TTGCCCTTATGATAAGCAAAGACAACATGAGATAAGAAGTGAGGTTGATGCAGTAATGGTAGGAGCTAATACGGTAAGAG
TAGACAACCCATCATTAACTGTAAAGTATAGTAAAAATAGGAGAAACCCCATTAGAGTAGTGGTGACTAGAAGTTTCAAT
CTAGACCCTTCATATAAGATATTCACCACACCACCCTCAACAATAGTCTATACTTCTAATTACGAAAGTGAAAAAGTTGA
GGAATTTAATAGGAAAGGAGTAATTGTTAGGAAATTTCTTCATTTAGATGACCTTTTAGAGGACTTATACAACAGCTTCA
ACGTTAAAAGACTAATGGTTGAAGGAGGTGGACATTTAATATGGTGGTTTATAAGAGACAATCTTTATGACGAAATTAGA
ATAACAATTTCTCCTAGAATTTTTGGAAATGGAGTCAGTTTTGCACAAGGAGATGGGTTTATTGGTGAGGATTCGCCTAG
GCTCACGTTAATTGATGCCAAAATTTGCGAATGTAGGAACGAAGTTCATCTTACGTACCAGAAATACATGGCATAA

Upstream 100 bases:

>100_bases
TTGTATTAAAGGTAAGTTTAACATATCTAGATAAAAATTGAATCTATCCATAAAGCAGTTTTCCACAAAACTCTTTTACT
CCAATTAGATCCTTTAGATT

Downstream 100 bases:

>100_bases
AAATATTTAGATCATATTATTAGCGATTATTCGAAAGTTTTCTCCTAATCTATTGTATGTTGAATACTCAATAGAACATA
AATATTTTGGTGAAAAATAT

Product: 5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: HTP reductase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MRPYVIIFSTLSIDGRLATKTGYSELSCPYDKQRQHEIRSEVDAVMVGANTVRVDNPSLTVKYSKNRRNPIRVVVTRSFN
LDPSYKIFTTPPSTIVYTSNYESEKVEEFNRKGVIVRKFLHLDDLLEDLYNSFNVKRLMVEGGGHLIWWFIRDNLYDEIR
ITISPRIFGNGVSFAQGDGFIGEDSPRLTLIDAKICECRNEVHLTYQKYMA

Sequences:

>Translated_211_residues
MRPYVIIFSTLSIDGRLATKTGYSELSCPYDKQRQHEIRSEVDAVMVGANTVRVDNPSLTVKYSKNRRNPIRVVVTRSFN
LDPSYKIFTTPPSTIVYTSNYESEKVEEFNRKGVIVRKFLHLDDLLEDLYNSFNVKRLMVEGGGHLIWWFIRDNLYDEIR
ITISPRIFGNGVSFAQGDGFIGEDSPRLTLIDAKICECRNEVHLTYQKYMA
>Mature_211_residues
MRPYVIIFSTLSIDGRLATKTGYSELSCPYDKQRQHEIRSEVDAVMVGANTVRVDNPSLTVKYSKNRRNPIRVVVTRSFN
LDPSYKIFTTPPSTIVYTSNYESEKVEEFNRKGVIVRKFLHLDDLLEDLYNSFNVKRLMVEGGGHLIWWFIRDNLYDEIR
ITISPRIFGNGVSFAQGDGFIGEDSPRLTLIDAKICECRNEVHLTYQKYMA

Specific function: Converts 2,5-Diamino-6-(Ribosylamino)-4(3h)-Pyrimidinone 5'-Phosphate Into 5-Amino-6-(Ribosylamino)-2,4(1h,3h)- Pyrimidinedione 5'-Phosphate. [C]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=182, Percent_Identity=26.3736263736264, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004794
- InterPro:   IPR006401
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF01872 RibD_C [H]

EC number: =1.1.1.193 [H]

Molecular weight: Translated: 24373; Mature: 24373

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPYVIIFSTLSIDGRLATKTGYSELSCPYDKQRQHEIRSEVDAVMVGANTVRVDNPSLT
CCCEEEEEEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHCEEEECCEEEEECCCEEE
VKYSKNRRNPIRVVVTRSFNLDPSYKIFTTPPSTIVYTSNYESEKVEEFNRKGVIVRKFL
EEECCCCCCCEEEEEEEECCCCCCEEEEECCCCEEEEECCCCHHHHHHHCCCCEEHHHHH
HLDDLLEDLYNSFNVKRLMVEGGGHLIWWFIRDNLYDEIRITISPRIFGNGVSFAQGDGF
HHHHHHHHHHCCCCEEEEEEECCCEEEEEEEECCCCEEEEEEECCEEECCCCCCCCCCCC
IGEDSPRLTLIDAKICECRNEVHLTYQKYMA
CCCCCCCEEEEECHHHHCCCCEEEEEHHHCC
>Mature Secondary Structure
MRPYVIIFSTLSIDGRLATKTGYSELSCPYDKQRQHEIRSEVDAVMVGANTVRVDNPSLT
CCCEEEEEEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHCEEEECCEEEEECCCEEE
VKYSKNRRNPIRVVVTRSFNLDPSYKIFTTPPSTIVYTSNYESEKVEEFNRKGVIVRKFL
EEECCCCCCCEEEEEEEECCCCCCEEEEECCCCEEEEECCCCHHHHHHHCCCCEEHHHHH
HLDDLLEDLYNSFNVKRLMVEGGGHLIWWFIRDNLYDEIRITISPRIFGNGVSFAQGDGF
HHHHHHHHHHCCCCEEEEEEECCCEEEEEEEECCCCEEEEEEECCEEECCCCCCCCCCCC
IGEDSPRLTLIDAKICECRNEVHLTYQKYMA
CCCCCCCEEEEECHHHHCCCCEEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726 [H]