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The map label for this gene is typA [H]

Identifier: 227816730

GI number: 227816730

Start: 3819582

End: 3821426

Strand: Reverse

Name: typA [H]

Synonym: BAMEG_4209

Alternate gene names: 227816730

Gene position: 3821426-3819582 (Counterclockwise)

Preceding gene: 227816732

Following gene: 227816729

Centisome position: 73.07

GC content: 38.37

Gene sequence:

>1845_bases
ATGTTGAAAAAACGACAAGATTTACGTAATATAGCAATTATTGCCCACGTTGACCATGGTAAAACAACACTTGTTGACCA
GTTATTACGTCAAGCGGGGACTTTCCGTGCGAACGAACACGTTGAAGAACGCGCAATGGATTCAAATGATCTAGAAAGAG
AACGCGGTATTACAATTTTAGCGAAAAATACTGCGATTCACTATGAAGATAAAAGAATTAACATTTTAGATACACCAGGT
CACGCTGACTTCGGTGGAGAAGTAGAACGTATTATGAAAATGGTTGATGGTGTATTACTTGTTGTTGATGCATATGAAGG
TTGTATGCCACAAACACGATTTGTTTTAAGGAAAGCTCTTGAGCAAAACTTAACTCCAATCGTAGTTGTAAATAAAATTG
ACCGTGACTTCGCTCGTCCTGATGAAGTAGTTGATGAAGTAATCGACTTATTCATCGAACTTGGTGCAAACGAAGATCAA
TTAGAGTTCCCAGTTGTATTTGCATCAGCAATGAACGGAACAGCAAGCTTAGATTCAAACCCAGCAAATCAAGAAGAGAA
TATGAAATCATTATTTGATACAATTATTGAACATATTCCTGCACCAATTGATAACAGCGAAGAGCCACTTCAATTCCAAG
TAGCACTTCTTGATTACAACGACTATGTTGGACGTATCGGGGTTGGACGCGTATTCCGCGGTACAATGAAGGTTGGACAA
CAAGTTGCTTTAATGAAAGTAGACGGAAGTGTAAAACAATTCCGCGTAACGAAACTATTTGGTTATATGGGATTAAAACG
TCAAGAAATTGAAGAAGCAAAAGCTGGAGACTTAGTAGCTGTTTCTGGTATGGAAGACATTAACGTAGGTGAAACAGTAT
GTCCAGTTGAACATCAAGATGCGTTACCATTATTACGTATTGATGAGCCAACACTACAAATGACATTCCTTGTAAATAAC
AGCCCATTTGCAGGTCGTGAAGGTAAATACATTACATCTCGTAAAATTGAAGAGCGTCTTCGTTCACAATTAGAAACAGA
TGTAAGTTTACGCGTAGATAATACAGAATCTCCTGATGCGTGGATCGTATCTGGACGTGGGGAACTACATTTATCTATCT
TAATCGAAAACATGCGTCGTGAAGGTTATGAACTACAAGTATCTAAACCAGAAGTAATCATTAAAGAAGTTGATGGCGTA
AGATGTGAGCCTGTAGAGCGTGTGCAAATTGATGTACCTGAAGAATACACTGGTTCTATTATGGAATCTATGGGTGCACG
TAAAGGTGAAATGTTAGATATGGTGAATAACGGAAACGGTCAAGTTCGCCTTACTTTCATGGTTCCAGCACGTGGTTTAA
TTGGTTACACAACAGAATTCTTAACATTAACTCGTGGTTACGGTATGTTAAACCATACATTCGATTGCTACCAACCAGTA
CACGCTGGACAAGTTGGTGGACGTCGTCAAGGTGTTCTAGTTTCACTTGAAACAGGAAAAGCATCACAATACGGTATTAT
GCAAGTTGAAGACCGTGGTGTAATCTTCGTTGAACCAGGTACAGAAGTATATGCTGGTATGATTGTTGGAGAACACACTC
GTGAGAATGACTTAACAGTTAACGTTGTGAAAATGAAACAACAAACTAACATTCGTTCTGCGACAAAAGATCAAACTTCA
ACAATGAAAAAACCACGCTTAATGACTTTAGAAGAGTCATTAGAGTACTTAAACGATGACGAGTTCTGTGAAGTAACTCC
AGAATCAATTCGTTTACGTAAAAAGATTCTTGATAAGAGCGAACGTGAAAGAGCTGCTAAGAAAAAGAAATCTGTAGAAG
CGTAA

Upstream 100 bases:

>100_bases
GAATACAACTATATTTTCATTCTTGATTTTATTTTAATTGCTATTGTATCCCCTTCGCTCTTATAATAGAGAAGGATTAA
AAAGACATTAGGAGTTGGAC

Downstream 100 bases:

>100_bases
AAAATAGAACAGCTATCTTAATTTAAGGTAGCTGTTTTTTATGTTTATTTTTTAGAATATTTACTCTTTTTAGTGGACAG
TATTTTTTTTGCGGGTTACT

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MLKKRQDLRNIAIIAHVDHGKTTLVDQLLRQAGTFRANEHVEERAMDSNDLERERGITILAKNTAIHYEDKRINILDTPG
HADFGGEVERIMKMVDGVLLVVDAYEGCMPQTRFVLRKALEQNLTPIVVVNKIDRDFARPDEVVDEVIDLFIELGANEDQ
LEFPVVFASAMNGTASLDSNPANQEENMKSLFDTIIEHIPAPIDNSEEPLQFQVALLDYNDYVGRIGVGRVFRGTMKVGQ
QVALMKVDGSVKQFRVTKLFGYMGLKRQEIEEAKAGDLVAVSGMEDINVGETVCPVEHQDALPLLRIDEPTLQMTFLVNN
SPFAGREGKYITSRKIEERLRSQLETDVSLRVDNTESPDAWIVSGRGELHLSILIENMRREGYELQVSKPEVIIKEVDGV
RCEPVERVQIDVPEEYTGSIMESMGARKGEMLDMVNNGNGQVRLTFMVPARGLIGYTTEFLTLTRGYGMLNHTFDCYQPV
HAGQVGGRRQGVLVSLETGKASQYGIMQVEDRGVIFVEPGTEVYAGMIVGEHTRENDLTVNVVKMKQQTNIRSATKDQTS
TMKKPRLMTLEESLEYLNDDEFCEVTPESIRLRKKILDKSERERAAKKKKSVEA

Sequences:

>Translated_614_residues
MLKKRQDLRNIAIIAHVDHGKTTLVDQLLRQAGTFRANEHVEERAMDSNDLERERGITILAKNTAIHYEDKRINILDTPG
HADFGGEVERIMKMVDGVLLVVDAYEGCMPQTRFVLRKALEQNLTPIVVVNKIDRDFARPDEVVDEVIDLFIELGANEDQ
LEFPVVFASAMNGTASLDSNPANQEENMKSLFDTIIEHIPAPIDNSEEPLQFQVALLDYNDYVGRIGVGRVFRGTMKVGQ
QVALMKVDGSVKQFRVTKLFGYMGLKRQEIEEAKAGDLVAVSGMEDINVGETVCPVEHQDALPLLRIDEPTLQMTFLVNN
SPFAGREGKYITSRKIEERLRSQLETDVSLRVDNTESPDAWIVSGRGELHLSILIENMRREGYELQVSKPEVIIKEVDGV
RCEPVERVQIDVPEEYTGSIMESMGARKGEMLDMVNNGNGQVRLTFMVPARGLIGYTTEFLTLTRGYGMLNHTFDCYQPV
HAGQVGGRRQGVLVSLETGKASQYGIMQVEDRGVIFVEPGTEVYAGMIVGEHTRENDLTVNVVKMKQQTNIRSATKDQTS
TMKKPRLMTLEESLEYLNDDEFCEVTPESIRLRKKILDKSERERAAKKKKSVEA
>Mature_614_residues
MLKKRQDLRNIAIIAHVDHGKTTLVDQLLRQAGTFRANEHVEERAMDSNDLERERGITILAKNTAIHYEDKRINILDTPG
HADFGGEVERIMKMVDGVLLVVDAYEGCMPQTRFVLRKALEQNLTPIVVVNKIDRDFARPDEVVDEVIDLFIELGANEDQ
LEFPVVFASAMNGTASLDSNPANQEENMKSLFDTIIEHIPAPIDNSEEPLQFQVALLDYNDYVGRIGVGRVFRGTMKVGQ
QVALMKVDGSVKQFRVTKLFGYMGLKRQEIEEAKAGDLVAVSGMEDINVGETVCPVEHQDALPLLRIDEPTLQMTFLVNN
SPFAGREGKYITSRKIEERLRSQLETDVSLRVDNTESPDAWIVSGRGELHLSILIENMRREGYELQVSKPEVIIKEVDGV
RCEPVERVQIDVPEEYTGSIMESMGARKGEMLDMVNNGNGQVRLTFMVPARGLIGYTTEFLTLTRGYGMLNHTFDCYQPV
HAGQVGGRRQGVLVSLETGKASQYGIMQVEDRGVIFVEPGTEVYAGMIVGEHTRENDLTVNVVKMKQQTNIRSATKDQTS
TMKKPRLMTLEESLEYLNDDEFCEVTPESIRLRKKILDKSERERAAKKKKSVEA

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=522, Percent_Identity=28.1609195402299, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI94966754, Length=137, Percent_Identity=45.2554744525547, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI4503483, Length=151, Percent_Identity=37.0860927152318, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI18390331, Length=197, Percent_Identity=34.5177664974619, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI19923640, Length=168, Percent_Identity=35.7142857142857, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI25306287, Length=168, Percent_Identity=35.7142857142857, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI25306283, Length=168, Percent_Identity=35.7142857142857, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI310132016, Length=115, Percent_Identity=41.7391304347826, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI310110807, Length=115, Percent_Identity=41.7391304347826, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI310123363, Length=115, Percent_Identity=41.7391304347826, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI34147630, Length=274, Percent_Identity=31.7518248175182, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI217272894, Length=198, Percent_Identity=30.3030303030303, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI217272892, Length=198, Percent_Identity=30.3030303030303, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI94966752, Length=133, Percent_Identity=33.0827067669173, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI53729339, Length=138, Percent_Identity=32.6086956521739, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI53729337, Length=138, Percent_Identity=32.6086956521739, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI48994988, Length=603, Percent_Identity=54.3946932006633, Blast_Score=689, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=512, Percent_Identity=28.515625, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1789738, Length=178, Percent_Identity=39.3258426966292, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790835, Length=145, Percent_Identity=35.1724137931034, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1789737, Length=282, Percent_Identity=28.3687943262411, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790412, Length=282, Percent_Identity=28.3687943262411, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789559, Length=166, Percent_Identity=34.3373493975904, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17557151, Length=513, Percent_Identity=25.5360623781676, Blast_Score=125, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17556745, Length=442, Percent_Identity=26.6968325791855, Blast_Score=119, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17533571, Length=175, Percent_Identity=38.8571428571429, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17506493, Length=163, Percent_Identity=33.1288343558282, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71988811, Length=133, Percent_Identity=37.593984962406, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71988819, Length=133, Percent_Identity=37.593984962406, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=37.3134328358209, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17556456, Length=316, Percent_Identity=28.4810126582279, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25141371, Length=278, Percent_Identity=27.3381294964029, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994658, Length=235, Percent_Identity=28.0851063829787, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323320, Length=515, Percent_Identity=28.1553398058252, Blast_Score=156, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6324707, Length=211, Percent_Identity=36.9668246445498, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320593, Length=211, Percent_Identity=36.9668246445498, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323098, Length=206, Percent_Identity=34.9514563106796, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6324761, Length=275, Percent_Identity=31.2727272727273, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324166, Length=180, Percent_Identity=33.8888888888889, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6322359, Length=148, Percent_Identity=35.8108108108108, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324550, Length=144, Percent_Identity=34.7222222222222, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI78706572, Length=518, Percent_Identity=25.8687258687259, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28574573, Length=142, Percent_Identity=42.2535211267606, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24585709, Length=155, Percent_Identity=37.4193548387097, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24585711, Length=154, Percent_Identity=37.6623376623377, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24585713, Length=154, Percent_Identity=37.6623376623377, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24582462, Length=195, Percent_Identity=35.3846153846154, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI281363316, Length=294, Percent_Identity=31.2925170068027, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI17864358, Length=294, Percent_Identity=31.2925170068027, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI21357743, Length=188, Percent_Identity=35.6382978723404, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI221458488, Length=161, Percent_Identity=40.9937888198758, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI19921738, Length=300, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28572034, Length=165, Percent_Identity=33.9393939393939, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 69081; Mature: 69081

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKRQDLRNIAIIAHVDHGKTTLVDQLLRQAGTFRANEHVEERAMDSNDLERERGITIL
CCCCHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHCCEEEE
AKNTAIHYEDKRINILDTPGHADFGGEVERIMKMVDGVLLVVDAYEGCMPQTRFVLRKAL
EECCEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EQNLTPIVVVNKIDRDFARPDEVVDEVIDLFIELGANEDQLEFPVVFASAMNGTASLDSN
HCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCC
PANQEENMKSLFDTIIEHIPAPIDNSEEPLQFQVALLDYNDYVGRIGVGRVFRGTMKVGQ
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCC
QVALMKVDGSVKQFRVTKLFGYMGLKRQEIEEAKAGDLVAVSGMEDINVGETVCPVEHQD
EEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEECCCCCCCCCCEECCCCCCC
ALPLLRIDEPTLQMTFLVNNSPFAGREGKYITSRKIEERLRSQLETDVSLRVDNTESPDA
CCCEEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEECCCCCCCE
WIVSGRGELHLSILIENMRREGYELQVSKPEVIIKEVDGVRCEPVERVQIDVPEEYTGSI
EEEECCCCEEEEEEEHHHHCCCCEEEECCCCEEEEECCCCCCCCCCEEEEECCHHHHHHH
MESMGARKGEMLDMVNNGNGQVRLTFMVPARGLIGYTTEFLTLTRGYGMLNHTFDCYQPV
HHHHCCCCCCEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCC
HAGQVGGRRQGVLVSLETGKASQYGIMQVEDRGVIFVEPGTEVYAGMIVGEHTRENDLTV
CCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCEEEECCCCCEEEEEEEECCCCCCCCEE
NVVKMKQQTNIRSATKDQTSTMKKPRLMTLEESLEYLNDDEFCEVTPESIRLRKKILDKS
EEEEEEHHCCCHHCCCHHHHHHCCCCEEEHHHHHHHCCCCCCEEECHHHHHHHHHHHCHH
ERERAAKKKKSVEA
HHHHHHHHHHCCCC
>Mature Secondary Structure
MLKKRQDLRNIAIIAHVDHGKTTLVDQLLRQAGTFRANEHVEERAMDSNDLERERGITIL
CCCCHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHCCEEEE
AKNTAIHYEDKRINILDTPGHADFGGEVERIMKMVDGVLLVVDAYEGCMPQTRFVLRKAL
EECCEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EQNLTPIVVVNKIDRDFARPDEVVDEVIDLFIELGANEDQLEFPVVFASAMNGTASLDSN
HCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCC
PANQEENMKSLFDTIIEHIPAPIDNSEEPLQFQVALLDYNDYVGRIGVGRVFRGTMKVGQ
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCC
QVALMKVDGSVKQFRVTKLFGYMGLKRQEIEEAKAGDLVAVSGMEDINVGETVCPVEHQD
EEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEECCCCCCCCCCEECCCCCCC
ALPLLRIDEPTLQMTFLVNNSPFAGREGKYITSRKIEERLRSQLETDVSLRVDNTESPDA
CCCEEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEECCCCCCCE
WIVSGRGELHLSILIENMRREGYELQVSKPEVIIKEVDGVRCEPVERVQIDVPEEYTGSI
EEEECCCCEEEEEEEHHHHCCCCEEEECCCCEEEEECCCCCCCCCCEEEEECCHHHHHHH
MESMGARKGEMLDMVNNGNGQVRLTFMVPARGLIGYTTEFLTLTRGYGMLNHTFDCYQPV
HHHHCCCCCCEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCC
HAGQVGGRRQGVLVSLETGKASQYGIMQVEDRGVIFVEPGTEVYAGMIVGEHTRENDLTV
CCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCEEEECCCCCEEEEEEEECCCCCCCCEE
NVVKMKQQTNIRSATKDQTSTMKKPRLMTLEESLEYLNDDEFCEVTPESIRLRKKILDKS
EEEEEEHHCCCHHCCCHHHHHHCCCCEEEHHHHHHHCCCCCCEEECHHHHHHHHHHHCHH
ERERAAKKKKSVEA
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]