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The map label for this gene is ctaB [H]

Identifier: 227816719

GI number: 227816719

Start: 3807939

End: 3808862

Strand: Reverse

Name: ctaB [H]

Synonym: BAMEG_4198

Alternate gene names: 227816719

Gene position: 3808862-3807939 (Counterclockwise)

Preceding gene: 227816721

Following gene: 227816718

Centisome position: 72.83

GC content: 34.96

Gene sequence:

>924_bases
ATGAACCATGCAACAAGTGAGCTGCATGATGAGTCTGCTGTTACAAGTATACCGGAAACAACTCGGTTACAAGATTTAAA
AGCACTCGTTAAAATGGGGATTGTAAACTCAAATACACTTACTGTATTTACAGGATTTTGGTTGGCATTACACTTTAATG
GATTAAGTGTGATGGACAATCTGGATAAGTTATTCTTTACAATCGTTGGTTCTGGATTAGTTATGGCAGGGGTATGTTGT
TTAAACAACTACATTGATCGAGACATCGATCCATTAATGGAAAGAACAAAGACCCGTCCAACGGTTACTGGAAAGTATAA
ACCAGGATTTGCACTTACATTTGGATTAGTTATATTACTTCTTGGGTTTGTATTTTTATTATTAACAACACCAATGGCAG
TTTTAATGGGGTTTATTGGTGCTTTCACATATGTTGTTCTATATAGTTTATGGACAAAGAGAAAGTATACACTAAATACT
GTTGTAGGTAGTATCTCTGGTGCAGTTCCACCTTTAATTGGATGGGCAGCAATCGATCCATCTTTAGGTCATCCAATTGC
TTGGATGCTATTTTTGATTATGTTTATTTGGCAAATCCCACATTTCCTTGCATTAGCAATGAAACGTGTTGATGAATATC
GAAATGCAGGAATTCCAATGCTTCCTGTAGTTCATGGATTTGAAATTACGAAACGCCAAATTATGATTTGGACAGTATGT
TTATTACCACTACCATTTTATATGAGTGGACTAGGGATAACATTTATGGTAATTGCAACACTGCTTAACATCGGATGGAT
CGTTTTAGGATTTTATGGCTTCCGTAAGAAAGATGACATCAAATGGTCCGTACAGATGTTTGTTTATTCCCTAAATTATT
TAACAATCTTATTTGTATCAATGATTGTAGTTACATTCTTCTAA

Upstream 100 bases:

>100_bases
AATGTTTCTACTGTAATAATATTGCTATATAGAGGCGAAATATTTCACTTTGAAATAGGCGCAAAAAGAAAGATGAAAGT
TTTAAGAGGGGGTTAAAGTG

Downstream 100 bases:

>100_bases
GACAACGACATAATTGGATTTCTTTACGTTGAGATTTACTTTACTTAACTATAAAGTACAATCTAATTCACAAGGAAAGT
GGGGGTTGTTTGTATGAAGA

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNHATSELHDESAVTSIPETTRLQDLKALVKMGIVNSNTLTVFTGFWLALHFNGLSVMDNLDKLFFTIVGSGLVMAGVCC
LNNYIDRDIDPLMERTKTRPTVTGKYKPGFALTFGLVILLLGFVFLLLTTPMAVLMGFIGAFTYVVLYSLWTKRKYTLNT
VVGSISGAVPPLIGWAAIDPSLGHPIAWMLFLIMFIWQIPHFLALAMKRVDEYRNAGIPMLPVVHGFEITKRQIMIWTVC
LLPLPFYMSGLGITFMVIATLLNIGWIVLGFYGFRKKDDIKWSVQMFVYSLNYLTILFVSMIVVTFF

Sequences:

>Translated_307_residues
MNHATSELHDESAVTSIPETTRLQDLKALVKMGIVNSNTLTVFTGFWLALHFNGLSVMDNLDKLFFTIVGSGLVMAGVCC
LNNYIDRDIDPLMERTKTRPTVTGKYKPGFALTFGLVILLLGFVFLLLTTPMAVLMGFIGAFTYVVLYSLWTKRKYTLNT
VVGSISGAVPPLIGWAAIDPSLGHPIAWMLFLIMFIWQIPHFLALAMKRVDEYRNAGIPMLPVVHGFEITKRQIMIWTVC
LLPLPFYMSGLGITFMVIATLLNIGWIVLGFYGFRKKDDIKWSVQMFVYSLNYLTILFVSMIVVTFF
>Mature_307_residues
MNHATSELHDESAVTSIPETTRLQDLKALVKMGIVNSNTLTVFTGFWLALHFNGLSVMDNLDKLFFTIVGSGLVMAGVCC
LNNYIDRDIDPLMERTKTRPTVTGKYKPGFALTFGLVILLLGFVFLLLTTPMAVLMGFIGAFTYVVLYSLWTKRKYTLNT
VVGSISGAVPPLIGWAAIDPSLGHPIAWMLFLIMFIWQIPHFLALAMKRVDEYRNAGIPMLPVVHGFEITKRQIMIWTVC
LLPLPFYMSGLGITFMVIATLLNIGWIVLGFYGFRKKDDIKWSVQMFVYSLNYLTILFVSMIVVTFF

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group [H]

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921982, Length=215, Percent_Identity=32.093023255814, Blast_Score=92, Evalue=9e-19,
Organism=Escherichia coli, GI1786631, Length=282, Percent_Identity=35.8156028368794, Blast_Score=161, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71998235, Length=234, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6325085, Length=247, Percent_Identity=29.9595141700405, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI19921064, Length=232, Percent_Identity=32.3275862068966, Blast_Score=98, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006369
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34550; Mature: 34550

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHATSELHDESAVTSIPETTRLQDLKALVKMGIVNSNTLTVFTGFWLALHFNGLSVMDN
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHH
LDKLFFTIVGSGLVMAGVCCLNNYIDRDIDPLMERTKTRPTVTGKYKPGFALTFGLVILL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHH
LGFVFLLLTTPMAVLMGFIGAFTYVVLYSLWTKRKYTLNTVVGSISGAVPPLIGWAAIDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHCCC
SLGHPIAWMLFLIMFIWQIPHFLALAMKRVDEYRNAGIPMLPVVHGFEITKRQIMIWTVC
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHH
LLPLPFYMSGLGITFMVIATLLNIGWIVLGFYGFRKKDDIKWSVQMFVYSLNYLTILFVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MIVVTFF
HHHHHCC
>Mature Secondary Structure
MNHATSELHDESAVTSIPETTRLQDLKALVKMGIVNSNTLTVFTGFWLALHFNGLSVMDN
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHH
LDKLFFTIVGSGLVMAGVCCLNNYIDRDIDPLMERTKTRPTVTGKYKPGFALTFGLVILL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHH
LGFVFLLLTTPMAVLMGFIGAFTYVVLYSLWTKRKYTLNTVVGSISGAVPPLIGWAAIDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHCCC
SLGHPIAWMLFLIMFIWQIPHFLALAMKRVDEYRNAGIPMLPVVHGFEITKRQIMIWTVC
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHH
LLPLPFYMSGLGITFMVIATLLNIGWIVLGFYGFRKKDDIKWSVQMFVYSLNYLTILFVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MIVVTFF
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA