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The map label for this gene is cysH [H]

Identifier: 227815731

GI number: 227815731

Start: 2875324

End: 2876004

Strand: Reverse

Name: cysH [H]

Synonym: BAMEG_3152

Alternate gene names: 227815731

Gene position: 2876004-2875324 (Counterclockwise)

Preceding gene: 227815732

Following gene: 227815730

Centisome position: 54.99

GC content: 37.0

Gene sequence:

>681_bases
ATGTTGACGTATGAAACGTGGGAAGAAAATGAAACGAAAGGCGCGCTATCAGTATTAAGTTGGGCGTATAAAGAATATAA
AAGTGAAATTGTATACGCATGTAGCTTCGGAGTGGAAGGGATGGTACTACTGGATCTTATTAACCAAGTAAATCCATCTG
CTAAAGTTGTATTTTTGGATACAAACGTACATTTTCAAGAAACGTATGAATTAATTCAAAAAGTGCGGGAACGATTTCCT
TCATTGAATATTATAGAAAAACAGCCAAAACTTACACTTGATGAACAAGACAAATTGCATGGTGACAAGCTATGGGAAAG
CAATCCTAATCTCTGTTGTAAGATTAGAAAAATTTTACCGTTAGAAGAATCATTAGCGAATGAAAAAGCGTGGATATCAG
GGTTGAGGAGAGAACAATCAGAAACGCGTAAGCATACAAAGTTTATAAATCAAGATCATCGTTTTCAATCTATTAAAGTT
TGTCCGCTCATTCATTGGACGTGGAAAGAAGTATGGCGATATGTATACAAGCATAGCTTGCCGTATAACTCATTACATGA
TATTGGATATCCAAGTATTGGGTGTGAGAAGTGTACGTTGCCTGTAGGAGAGGGTGGCGATTCGAGAGATGGTAGATGGG
CTGGGAAAGTGAAAACTGAATGTGGTCTTCATTATCAATAA

Upstream 100 bases:

>100_bases
TACGTTTAAAGTAAAAAGCGCTGACTAGAAAAACTAGAGGCGGTTTTAACCTATTTCATTAGGTTAAAACCGTCTTTTTG
CTTTTACAGGGGGAAAAAAC

Downstream 100 bases:

>100_bases
GATGAATCTTGAAATAAAACAAAGAGGAGATATAGAAAATGAGTACAGTAAACGAATTGGTAAACCTTGTAGACGAGACA
TATGACATATCACAAATTGA

Product: phosphoadenylyl-sulfate reductase (thioredoxin)

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MLTYETWEENETKGALSVLSWAYKEYKSEIVYACSFGVEGMVLLDLINQVNPSAKVVFLDTNVHFQETYELIQKVRERFP
SLNIIEKQPKLTLDEQDKLHGDKLWESNPNLCCKIRKILPLEESLANEKAWISGLRREQSETRKHTKFINQDHRFQSIKV
CPLIHWTWKEVWRYVYKHSLPYNSLHDIGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ

Sequences:

>Translated_226_residues
MLTYETWEENETKGALSVLSWAYKEYKSEIVYACSFGVEGMVLLDLINQVNPSAKVVFLDTNVHFQETYELIQKVRERFP
SLNIIEKQPKLTLDEQDKLHGDKLWESNPNLCCKIRKILPLEESLANEKAWISGLRREQSETRKHTKFINQDHRFQSIKV
CPLIHWTWKEVWRYVYKHSLPYNSLHDIGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ
>Mature_226_residues
MLTYETWEENETKGALSVLSWAYKEYKSEIVYACSFGVEGMVLLDLINQVNPSAKVVFLDTNVHFQETYELIQKVRERFP
SLNIIEKQPKLTLDEQDKLHGDKLWESNPNLCCKIRKILPLEESLANEKAWISGLRREQSETRKHTKFINQDHRFQSIKV
CPLIHWTWKEVWRYVYKHSLPYNSLHDIGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=225, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6325425, Length=217, Percent_Identity=31.3364055299539, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 26393; Mature: 26393

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTYETWEENETKGALSVLSWAYKEYKSEIVYACSFGVEGMVLLDLINQVNPSAKVVFLD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCCEEEEEE
TNVHFQETYELIQKVRERFPSLNIIEKQPKLTLDEQDKLHGDKLWESNPNLCCKIRKILP
CCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHCCCCHHHCCCCCCEEHHHHHCC
LEESLANEKAWISGLRREQSETRKHTKFINQDHRFQSIKVCPLIHWTWKEVWRYVYKHSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECEEEEHHHHHHHHHHHHHCC
PYNSLHDIGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCEECCCCCCCC
>Mature Secondary Structure
MLTYETWEENETKGALSVLSWAYKEYKSEIVYACSFGVEGMVLLDLINQVNPSAKVVFLD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCCEEEEEE
TNVHFQETYELIQKVRERFPSLNIIEKQPKLTLDEQDKLHGDKLWESNPNLCCKIRKILP
CCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHCCCCHHHCCCCCCEEHHHHHCC
LEESLANEKAWISGLRREQSETRKHTKFINQDHRFQSIKVCPLIHWTWKEVWRYVYKHSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECEEEEHHHHHHHHHHHHHCC
PYNSLHDIGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA