| Definition | Bacillus anthracis str. CDC 684, complete genome. |
|---|---|
| Accession | NC_012581 |
| Length | 5,230,115 |
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The map label for this gene is fabG [H]
Identifier: 227815332
GI number: 227815332
Start: 2508982
End: 2509740
Strand: Direct
Name: fabG [H]
Synonym: BAMEG_2744
Alternate gene names: 227815332
Gene position: 2508982-2509740 (Clockwise)
Preceding gene: 227815325
Following gene: 227815333
Centisome position: 47.97
GC content: 38.08
Gene sequence:
>759_bases ATGTTAAAAGGAAAAGTAGCATTAGTTACAGGAGCAAGCCGAGGAATTGGACGTGCTATTGCAAAACGTTTAGCAAACGA CGGTGCATTAGTTGCTATTCATTATGGTAATCGAAAAGAAGAGGCTGAAGAAACCGTTTATGAAATCCAGTCAAATGGCG GATCAGCTTTTTCCATCGGTGCAAACCTTGAATCTTTACATGGTGTAGAAGCTCTTTATAGTTCTTTAGATAACGAATTA CAAAACAGAACTGGTAGTACTAAATTTGATATTTTAATAAACAACGCTGGAATTGGTCCTGGTGCTTTTATTGAAGAAAC GACTGAACAATTTTTTGATAGAATGGTTTCAGTAAATGCAAAAGCACCATTCTTTATCATCCAACAAGCTCTATCTCGTT TACGTGACAATAGCCGAATTATTAATATTTCATCCGCTGCCACACGAATTTCTTTACCTGATTTCATTGCATATAGTATG ACGAAAGGCGCTATTAATACAATGACTTTCACACTAGCAAAACAGCTCGGAGCAAGAGGAATAACAGTGAATGCAATACT TCCAGGATTTGTTAAAACAGATATGAATGCAGAACTCTTGAGTGACCCAATGATGAAACAATACGCCACTACTATTTCCG CTTTCAATCGCTTAGGTGAAGTAGAAGACATTGCCGACACTGCTGCATTTCTCGCTTCTCCAGACAGCCGCTGGGTTACT GGACAATTAATTGATGTTAGCGGAGGATCTTGTTTATAA
Upstream 100 bases:
>100_bases CTTCTTACACATACTCATATATTACTTAAGTATGTCCGCATTACTACATAAAGAAAAATAACTTAAAAACATTTAAAATT TATGAGGAGATGAGAAAACT
Downstream 100 bases:
>100_bases AAAAGCATATATTTTCAAATCTTTTTTATTGCGCAATAAAACAATTTATATAATACTATATAAAACATATATATTTAGGA GGATTACAGCAATGTCCGAA
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 252; Mature: 252
Protein sequence:
>252_residues MLKGKVALVTGASRGIGRAIAKRLANDGALVAIHYGNRKEEAEETVYEIQSNGGSAFSIGANLESLHGVEALYSSLDNEL QNRTGSTKFDILINNAGIGPGAFIEETTEQFFDRMVSVNAKAPFFIIQQALSRLRDNSRIINISSAATRISLPDFIAYSM TKGAINTMTFTLAKQLGARGITVNAILPGFVKTDMNAELLSDPMMKQYATTISAFNRLGEVEDIADTAAFLASPDSRWVT GQLIDVSGGSCL
Sequences:
>Translated_252_residues MLKGKVALVTGASRGIGRAIAKRLANDGALVAIHYGNRKEEAEETVYEIQSNGGSAFSIGANLESLHGVEALYSSLDNEL QNRTGSTKFDILINNAGIGPGAFIEETTEQFFDRMVSVNAKAPFFIIQQALSRLRDNSRIINISSAATRISLPDFIAYSM TKGAINTMTFTLAKQLGARGITVNAILPGFVKTDMNAELLSDPMMKQYATTISAFNRLGEVEDIADTAAFLASPDSRWVT GQLIDVSGGSCL >Mature_252_residues MLKGKVALVTGASRGIGRAIAKRLANDGALVAIHYGNRKEEAEETVYEIQSNGGSAFSIGANLESLHGVEALYSSLDNEL QNRTGSTKFDILINNAGIGPGAFIEETTEQFFDRMVSVNAKAPFFIIQQALSRLRDNSRIINISSAATRISLPDFIAYSM TKGAINTMTFTLAKQLGARGITVNAILPGFVKTDMNAELLSDPMMKQYATTISAFNRLGEVEDIADTAAFLASPDSRWVT GQLIDVSGGSCL
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=32.1428571428571, Blast_Score=120, Evalue=1e-27, Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=33.0708661417323, Blast_Score=120, Evalue=1e-27, Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=33.9920948616601, Blast_Score=119, Evalue=4e-27, Organism=Homo sapiens, GI126723750, Length=265, Percent_Identity=30.188679245283, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI33667109, Length=200, Percent_Identity=33.5, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=29.9212598425197, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI209862901, Length=227, Percent_Identity=27.3127753303965, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI19923983, Length=227, Percent_Identity=27.3127753303965, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=26.7206477732794, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI19923817, Length=270, Percent_Identity=25.5555555555556, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI126723191, Length=193, Percent_Identity=30.0518134715026, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI59889578, Length=171, Percent_Identity=32.1637426900585, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI109715829, Length=242, Percent_Identity=29.3388429752066, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI10190746, Length=272, Percent_Identity=28.3088235294118, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=33.4661354581673, Blast_Score=135, Evalue=3e-33, Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=30.4878048780488, Blast_Score=110, Evalue=8e-26, Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=34.251968503937, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=29.8804780876494, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=34.2629482071713, Blast_Score=103, Evalue=9e-24, Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=32.824427480916, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=31.1787072243346, Blast_Score=97, Evalue=7e-22, Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=30.952380952381, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=30.8300395256917, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=30.3149606299213, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI1789057, Length=264, Percent_Identity=30.3030303030303, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1787545, Length=255, Percent_Identity=22.7450980392157, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=26.0536398467433, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1787820, Length=189, Percent_Identity=27.5132275132275, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI17561402, Length=262, Percent_Identity=34.7328244274809, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=31.6205533596838, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=30.7086614173228, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17555706, Length=253, Percent_Identity=31.2252964426877, Blast_Score=104, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=33.7121212121212, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=32, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=32.9588014981273, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=32.8301886792453, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17531453, Length=275, Percent_Identity=32.7272727272727, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=29.3172690763052, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=32.5842696629214, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=32.7067669172932, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17536025, Length=258, Percent_Identity=29.0697674418605, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=27.3092369477912, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=30.188679245283, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17555612, Length=220, Percent_Identity=30.9090909090909, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=28.6792452830189, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=27.5193798449612, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=29.4339622641509, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=31.5985130111524, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI71982365, Length=210, Percent_Identity=31.4285714285714, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=32.2097378277154, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17508895, Length=199, Percent_Identity=31.6582914572864, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17561272, Length=258, Percent_Identity=30.6201550387597, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17564282, Length=200, Percent_Identity=28, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=29.277566539924, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=30.5660377358491, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI72001658, Length=213, Percent_Identity=28.6384976525822, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17558628, Length=253, Percent_Identity=29.6442687747036, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=28.1954887218045, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=29.811320754717, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI86565303, Length=214, Percent_Identity=28.9719626168224, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17538480, Length=272, Percent_Identity=28.3088235294118, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=29.9242424242424, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=27.5590551181102, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71997099, Length=213, Percent_Identity=29.1079812206573, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=25, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI24643142, Length=251, Percent_Identity=37.8486055776892, Blast_Score=133, Evalue=9e-32, Organism=Drosophila melanogaster, GI24639444, Length=254, Percent_Identity=35.4330708661417, Blast_Score=125, Evalue=4e-29, Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=34.765625, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI28571526, Length=261, Percent_Identity=31.4176245210728, Blast_Score=114, Evalue=8e-26, Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=31.496062992126, Blast_Score=110, Evalue=6e-25, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=32.6771653543307, Blast_Score=108, Evalue=5e-24, Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=29.8850574712644, Blast_Score=98, Evalue=6e-21, Organism=Drosophila melanogaster, GI24644337, Length=258, Percent_Identity=29.8449612403101, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI21357673, Length=253, Percent_Identity=26.4822134387352, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24640492, Length=200, Percent_Identity=27.5, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI22024069, Length=208, Percent_Identity=31.7307692307692, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI28573296, Length=208, Percent_Identity=32.2115384615385, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI45554248, Length=222, Percent_Identity=32.4324324324324, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24640117, Length=222, Percent_Identity=32.4324324324324, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI19921754, Length=221, Percent_Identity=30.316742081448, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27006; Mature: 27006
Theoretical pI: Translated: 5.36; Mature: 5.36
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLKGKVALVTGASRGIGRAIAKRLANDGALVAIHYGNRKEEAEETVYEIQSNGGSAFSIG CCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEC ANLESLHGVEALYSSLDNELQNRTGSTKFDILINNAGIGPGAFIEETTEQFFDRMVSVNA CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCC KAPFFIIQQALSRLRDNSRIINISSAATRISLPDFIAYSMTKGAINTMTFTLAKQLGARG CCCHHHHHHHHHHHCCCCEEEEEECCHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCC ITVNAILPGFVKTDMNAELLSDPMMKQYATTISAFNRLGEVEDIADTAAFLASPDSRWVT EEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEE GQLIDVSGGSCL EEEEECCCCCCC >Mature Secondary Structure MLKGKVALVTGASRGIGRAIAKRLANDGALVAIHYGNRKEEAEETVYEIQSNGGSAFSIG CCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEC ANLESLHGVEALYSSLDNELQNRTGSTKFDILINNAGIGPGAFIEETTEQFFDRMVSVNA CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCC KAPFFIIQQALSRLRDNSRIINISSAATRISLPDFIAYSMTKGAINTMTFTLAKQLGARG CCCHHHHHHHHHHHCCCCEEEEEECCHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCC ITVNAILPGFVKTDMNAELLSDPMMKQYATTISAFNRLGEVEDIADTAAFLASPDSRWVT EEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEE GQLIDVSGGSCL EEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA