Click here to switch to the map view.

The map label for this gene is ykoH [H]

Identifier: 227814972

GI number: 227814972

Start: 2171711

End: 2173069

Strand: Reverse

Name: ykoH [H]

Synonym: BAMEG_2383

Alternate gene names: 227814972

Gene position: 2173069-2171711 (Counterclockwise)

Preceding gene: 227814973

Following gene: 227814971

Centisome position: 41.55

GC content: 30.61

Gene sequence:

>1359_bases
ATGAAAATTAAAAATAAAATATATTTATTCTCTACAGTATGGTTACTACTTATTTTATTAATTATTAATAGTTCAATATA
TTTTTTGTTTTATAAAGTGACTACGAACGGAGAGTTAGAACGATTGAAACGTGAGGCAATACATATCATTGATGGAATGA
ACGCGGATTCAGCAAAGAAAGTAGATGCAATAAGTCTATTGCAACCATACTTACCTTCAAATGGTATGATTAGAATTATT
AATGAAAATTCAAAGGTAATGATTAGGCAAGAAGTGGATAGTACAAAACCAATTCCAGCATTAAATACGAAATTTGAAAG
AAAAGAGTCAGCTGGAATTTATGAGAAGAACGAGGGTAAATTTGCCTATATAAAAATACCAATCATTTGGAATGATGGGA
AAATCGTTTCGTTAGAAATGACAGAACGTTTAGATAGTTTGCAAGAGAATTTAAATATGTTAAAAAATGTATTAGTTATT
GCATCACTTCTCGTTTTAATTCCGTCTTTTTTTGCAGGAAGAATGTTAAGTAAGTTTATTTTAAAACCTGTAAATTCTTT
AATACAAACTATGGAGCATATACAAGTTAGAGGGATATTCAAAAAAATACCGCTTGAGAACAAGTCAAAAGATGAACTGC
ACAAAATGGGATCGACATTTAATAAAATGATTGATTTATTACATCAGAACTTTGAAAAGCAGCAACAGTTCGTTTCAGAT
GCTTCGCATGAATTAAGAACACCGTTAACAGTTATTGAAAGTTATGCGAAATTATTAAAAAGATGGGGAATGAAAAAACA
AGATGTTTTGGAAGAATCTGTAGAAGCGATTTATTCAGAGGCAGTAAGAATGAAAGGTATGACGAATCAAATGTTGCTTC
TTGCAAATAGTAGTGCTGATTGGAGTTTGGAGACTAACGAATCAGATTTAGTCCGATTATGTCAGGTGACTGCTGAGCAG
TTAGAAAAAACATATGCTCGGAATTTTCGTGTTATAACAGATGAAGAAAAAATTGTTGTAAATATTGACGAACAAAAAAT
AAAACAAGTATTAGTAGTTTTATTAGATAATGCAATGAAATACAGTAAAGATTCTATAGATATTATAGTAGGAATACAAA
AAGAAAAAGTCTTTTTTTCTATTCAAGATTACGGTATGGGAATTCCTAAAGAAGATATACAGAAAGTATTTGACCGTTTC
TTTCGAGTTGATAAAGCGAGGAGTAGGGAAACAGGGGGGACTGGTTTAGGTTTATCGATTGCCAAACAAATTATTGATGC
TCATGAAGGAGATATACAACTTGAAAGTGAAGAAGGAAAATGGACGAAAGTTACAGTAAATTTACCTCATTTTTCATAA

Upstream 100 bases:

>100_bases
CGTATATATTCGATATTTGCGCAAAAAAGTAGATTGTAATGTGGACGTACCACTTATTCACACTGTTAGAGGTGTTGGGT
ATGTCTTAAAGGTGTAACAT

Downstream 100 bases:

>100_bases
AGAGATAGGAGCTTTAAACATGAAAAAGAAATGGAAAATTGCATTGTTAGTTTGCTTCACGGTTGTAAGTGTAGCGTTTG
TATCACAACGTATTGTTTCT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKIKNKIYLFSTVWLLLILLIINSSIYFLFYKVTTNGELERLKREAIHIIDGMNADSAKKVDAISLLQPYLPSNGMIRII
NENSKVMIRQEVDSTKPIPALNTKFERKESAGIYEKNEGKFAYIKIPIIWNDGKIVSLEMTERLDSLQENLNMLKNVLVI
ASLLVLIPSFFAGRMLSKFILKPVNSLIQTMEHIQVRGIFKKIPLENKSKDELHKMGSTFNKMIDLLHQNFEKQQQFVSD
ASHELRTPLTVIESYAKLLKRWGMKKQDVLEESVEAIYSEAVRMKGMTNQMLLLANSSADWSLETNESDLVRLCQVTAEQ
LEKTYARNFRVITDEEKIVVNIDEQKIKQVLVVLLDNAMKYSKDSIDIIVGIQKEKVFFSIQDYGMGIPKEDIQKVFDRF
FRVDKARSRETGGTGLGLSIAKQIIDAHEGDIQLESEEGKWTKVTVNLPHFS

Sequences:

>Translated_452_residues
MKIKNKIYLFSTVWLLLILLIINSSIYFLFYKVTTNGELERLKREAIHIIDGMNADSAKKVDAISLLQPYLPSNGMIRII
NENSKVMIRQEVDSTKPIPALNTKFERKESAGIYEKNEGKFAYIKIPIIWNDGKIVSLEMTERLDSLQENLNMLKNVLVI
ASLLVLIPSFFAGRMLSKFILKPVNSLIQTMEHIQVRGIFKKIPLENKSKDELHKMGSTFNKMIDLLHQNFEKQQQFVSD
ASHELRTPLTVIESYAKLLKRWGMKKQDVLEESVEAIYSEAVRMKGMTNQMLLLANSSADWSLETNESDLVRLCQVTAEQ
LEKTYARNFRVITDEEKIVVNIDEQKIKQVLVVLLDNAMKYSKDSIDIIVGIQKEKVFFSIQDYGMGIPKEDIQKVFDRF
FRVDKARSRETGGTGLGLSIAKQIIDAHEGDIQLESEEGKWTKVTVNLPHFS
>Mature_452_residues
MKIKNKIYLFSTVWLLLILLIINSSIYFLFYKVTTNGELERLKREAIHIIDGMNADSAKKVDAISLLQPYLPSNGMIRII
NENSKVMIRQEVDSTKPIPALNTKFERKESAGIYEKNEGKFAYIKIPIIWNDGKIVSLEMTERLDSLQENLNMLKNVLVI
ASLLVLIPSFFAGRMLSKFILKPVNSLIQTMEHIQVRGIFKKIPLENKSKDELHKMGSTFNKMIDLLHQNFEKQQQFVSD
ASHELRTPLTVIESYAKLLKRWGMKKQDVLEESVEAIYSEAVRMKGMTNQMLLLANSSADWSLETNESDLVRLCQVTAEQ
LEKTYARNFRVITDEEKIVVNIDEQKIKQVLVVLLDNAMKYSKDSIDIIVGIQKEKVFFSIQDYGMGIPKEDIQKVFDRF
FRVDKARSRETGGTGLGLSIAKQIIDAHEGDIQLESEEGKWTKVTVNLPHFS

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=329, Percent_Identity=28.5714285714286, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790346, Length=277, Percent_Identity=28.158844765343, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788393, Length=277, Percent_Identity=27.4368231046931, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1786783, Length=335, Percent_Identity=28.3582089552239, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788713, Length=230, Percent_Identity=30.4347826086957, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789808, Length=269, Percent_Identity=27.8810408921933, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1787894, Length=242, Percent_Identity=25.2066115702479, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=26.4462809917355, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=26.1802575107296, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790861, Length=252, Percent_Identity=24.6031746031746, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787374, Length=274, Percent_Identity=25.1824817518248, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=210, Percent_Identity=27.6190476190476, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788549, Length=221, Percent_Identity=27.6018099547511, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87082128, Length=294, Percent_Identity=23.8095238095238, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788279, Length=231, Percent_Identity=26.4069264069264, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789403, Length=459, Percent_Identity=22.6579520697168, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790551, Length=301, Percent_Identity=23.2558139534884, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=23.1481481481481, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51858; Mature: 51858

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKNKIYLFSTVWLLLILLIINSSIYFLFYKVTTNGELERLKREAIHIIDGMNADSAKK
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHH
VDAISLLQPYLPSNGMIRIINENSKVMIRQEVDSTKPIPALNTKFERKESAGIYEKNEGK
HHHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHCCCCEECCCCC
FAYIKIPIIWNDGKIVSLEMTERLDSLQENLNMLKNVLVIASLLVLIPSFFAGRMLSKFI
EEEEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKPVNSLIQTMEHIQVRGIFKKIPLENKSKDELHKMGSTFNKMIDLLHQNFEKQQQFVSD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASHELRTPLTVIESYAKLLKRWGMKKQDVLEESVEAIYSEAVRMKGMTNQMLLLANSSAD
HHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
WSLETNESDLVRLCQVTAEQLEKTYARNFRVITDEEKIVVNIDEQKIKQVLVVLLDNAMK
CEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCHHHHHHHHHHHHHHHHH
YSKDSIDIIVGIQKEKVFFSIQDYGMGIPKEDIQKVFDRFFRVDKARSRETGGTGLGLSI
CCCCCEEEEEEEECCEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AKQIIDAHEGDIQLESEEGKWTKVTVNLPHFS
HHHHHHCCCCCEEEECCCCCEEEEEEECCCCC
>Mature Secondary Structure
MKIKNKIYLFSTVWLLLILLIINSSIYFLFYKVTTNGELERLKREAIHIIDGMNADSAKK
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHH
VDAISLLQPYLPSNGMIRIINENSKVMIRQEVDSTKPIPALNTKFERKESAGIYEKNEGK
HHHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHCCCCEECCCCC
FAYIKIPIIWNDGKIVSLEMTERLDSLQENLNMLKNVLVIASLLVLIPSFFAGRMLSKFI
EEEEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKPVNSLIQTMEHIQVRGIFKKIPLENKSKDELHKMGSTFNKMIDLLHQNFEKQQQFVSD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASHELRTPLTVIESYAKLLKRWGMKKQDVLEESVEAIYSEAVRMKGMTNQMLLLANSSAD
HHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
WSLETNESDLVRLCQVTAEQLEKTYARNFRVITDEEKIVVNIDEQKIKQVLVVLLDNAMK
CEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCHHHHHHHHHHHHHHHHH
YSKDSIDIIVGIQKEKVFFSIQDYGMGIPKEDIQKVFDRFFRVDKARSRETGGTGLGLSI
CCCCCEEEEEEEECCEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AKQIIDAHEGDIQLESEEGKWTKVTVNLPHFS
HHHHHHCCCCCEEEECCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]