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The map label for this gene is ampC [C]

Identifier: 227814914

GI number: 227814914

Start: 2122565

End: 2123206

Strand: Reverse

Name: ampC [C]

Synonym: BAMEG_2325

Alternate gene names: 227814914

Gene position: 2123206-2122565 (Counterclockwise)

Preceding gene: 227814917

Following gene: 227814913

Centisome position: 40.6

GC content: 38.63

Gene sequence:

>642_bases
ATGAAAACATGCAGTAAAATTACATGTGCAAGTCTATCACTTTTAATAGCTGGAAGTTCCCTGTTATACATAACACCAGC
CTCAATTGTAAAAGCAGAACCTACGCAAAATGTATCTAGTTCGTTACAAACAAGTATGCAAAGCGATCGTACTTCCGTTA
AGAAAGCAATACGGGATGCACTACAACTTGGATACCCGGGAATACTCGCTAACATTTCTAAGGGTGGTAAAACCTGGAGT
TATACCGCTGGGTTAGCAGATGTGAGAACCAAGAAACCAATGAAAGCAGATTTTCGCTTTCGTATTGGCAGTGTGACGAA
AACGTTCATTGCAACAGTTCTACTTCAATTATCTGGAGAGAACCGTTTGAATCTAGATGACTCCATTGAAAAATGGTTGC
CTGGTGTCATTCAAGGAAACGGATATGATGGTAACCAAATTACGATCCGGCAAATATTGAATCATACAAGTGGTATTGCT
GACTATATAAATTCAAAAGACTTTGATATTACGGATATAAAAAAATCGTATACGGCTGAAGAATTTGTAAAGATGGGGAT
TTCTCTTCCCCCCAGACTTTGCTCCAGGGAAGGGTTGGTCTTATTCAAATACAGGATACGTAATACTAGGAATCCTTATT
GA

Upstream 100 bases:

>100_bases
AGTGTTGACTTTTATCATTGGGAGAGTTGATAGCTGTGTGGTTAGTATATGACATACCTATCAACCATCAATACAATTTA
AATAGAGAAGAGGATGCTTT

Downstream 100 bases:

>100_bases
AAAAGTAACAGGAAACAGCTATGCGGAAGAGGTTGAAAATCGGATTATTGAACCGCTTGATTTATCAAATACATTCCTAC
CTGGCAATTCAAGCGTGATT

Product: putative D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSMQSDRTSVKKAIRDALQLGYPGILANISKGGKTWS
YTAGLADVRTKKPMKADFRFRIGSVTKTFIATVLLQLSGENRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIA
DYINSKDFDITDIKKSYTAEEFVKMGISLPPRLCSREGLVLFKYRIRNTRNPY

Sequences:

>Translated_213_residues
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSMQSDRTSVKKAIRDALQLGYPGILANISKGGKTWS
YTAGLADVRTKKPMKADFRFRIGSVTKTFIATVLLQLSGENRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIA
DYINSKDFDITDIKKSYTAEEFVKMGISLPPRLCSREGLVLFKYRIRNTRNPY
>Mature_213_residues
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSMQSDRTSVKKAIRDALQLGYPGILANISKGGKTWS
YTAGLADVRTKKPMKADFRFRIGSVTKTFIATVLLQLSGENRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIA
DYINSKDFDITDIKKSYTAEEFVKMGISLPPRLCSREGLVLFKYRIRNTRNPY

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Homo sapiens, GI26051233, Length=159, Percent_Identity=28.3018867924528, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI26051231, Length=159, Percent_Identity=28.3018867924528, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 23533; Mature: 23533

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSMQSDRTSVKKAIRDA
CCCCHHHHHHHHHHHHCCCCEEEECCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LQLGYPGILANISKGGKTWSYTAGLADVRTKKPMKADFRFRIGSVTKTFIATVLLQLSGE
HHCCCCHHEEECCCCCCEEEEECCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCC
NRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIADYINSKDFDITDIKKSYTAE
CCCCCCHHHHHHCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EFVKMGISLPPRLCSREGLVLFKYRIRNTRNPY
HHHHHCCCCCHHHHCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSMQSDRTSVKKAIRDA
CCCCHHHHHHHHHHHHCCCCEEEECCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LQLGYPGILANISKGGKTWSYTAGLADVRTKKPMKADFRFRIGSVTKTFIATVLLQLSGE
HHCCCCHHEEECCCCCCEEEEECCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCC
NRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIADYINSKDFDITDIKKSYTAE
CCCCCCHHHHHHCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EFVKMGISLPPRLCSREGLVLFKYRIRNTRNPY
HHHHHCCCCCHHHHCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]