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The map label for this gene is glcR [H]

Identifier: 227814423

GI number: 227814423

Start: 1663827

End: 1664597

Strand: Direct

Name: glcR [H]

Synonym: BAMEG_1831

Alternate gene names: 227814423

Gene position: 1663827-1664597 (Clockwise)

Preceding gene: 227814421

Following gene: 227814424

Centisome position: 31.81

GC content: 32.56

Gene sequence:

>771_bases
ATGTTTACTGAAGAGCGTAGAGAGAAAATTTTAGAGTTACTTAAGAAAAATGGAAGGGTAATTGCAAAGGATCTTGCGGA
AAGTTTCGATATGTCTATCGATTCTATAAGAAGAGATTTGTCTATTATGGAGAAGGATGGCTTGTTAAAAAGAACACATG
GAGGAGCAATTGAACTTGCTAGAGTAAGGAATTTAGCTACCAAGCCATTGAAACGTTATAGTAATGGTTCTGTATATGAA
GACGCAATTGCAAAAATCGCAGCTTCTTATATACAAGAAGGAGATTCCGTTTTTATTGGTGGAGCTTCTATTCATTATGC
CATGTTAAAATATTTACCTGAAACATCATTTACAGTTATTACGAATGCTTTAGAAATTGCTAGTACGTTACAGGAATATA
AGAACATCGATATGTACTTAATTGGTGGCATGGTGAAACCATCAGGAAATATGACAGATACACTTGCTTCAGAGTTAATA
AGTAGATTTTCTATTGATCTTAATTTTTCTACAGGTGATGGTATTTCATTAAACGGTATAAGTACTGCAACGCCGGAAGT
TGCTTTTTTTAGTAAAACAGTAAGTAAGATTGCTAGAAGAAATATTTGTTTAGCTCCTCATAATAAACTTGGAATAGACT
ACTTTATAAAAGGAGAGTCACTGATTGAAATTGATCTTATAATAACAGATTCGGAGGCTAGTAAAGAAACAATTCAAGAA
TTTGAGAAACAAGGTAAAGAAATTGTAATAGCATCAATAGACTACGTTTAA

Upstream 100 bases:

>100_bases
CGGAGTGAATAAGAATTGAAAATATTGTAAAGCGGAAGAGACATGCATATAATTAAAATAAGGATAAGATTTCAGAATCT
TCAATAACGGCGGTGGACAC

Downstream 100 bases:

>100_bases
AAGGAGTTTGAAATGATTATAAAAAGACAAGAATTTCATATAAATGGACTAACTTATACAATTCGTTCTGCAGCTGAAAC
AGATGCGGAACAGTTATCGG

Product: transcriptional regulator, DeoR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MFTEERREKILELLKKNGRVIAKDLAESFDMSIDSIRRDLSIMEKDGLLKRTHGGAIELARVRNLATKPLKRYSNGSVYE
DAIAKIAASYIQEGDSVFIGGASIHYAMLKYLPETSFTVITNALEIASTLQEYKNIDMYLIGGMVKPSGNMTDTLASELI
SRFSIDLNFSTGDGISLNGISTATPEVAFFSKTVSKIARRNICLAPHNKLGIDYFIKGESLIEIDLIITDSEASKETIQE
FEKQGKEIVIASIDYV

Sequences:

>Translated_256_residues
MFTEERREKILELLKKNGRVIAKDLAESFDMSIDSIRRDLSIMEKDGLLKRTHGGAIELARVRNLATKPLKRYSNGSVYE
DAIAKIAASYIQEGDSVFIGGASIHYAMLKYLPETSFTVITNALEIASTLQEYKNIDMYLIGGMVKPSGNMTDTLASELI
SRFSIDLNFSTGDGISLNGISTATPEVAFFSKTVSKIARRNICLAPHNKLGIDYFIKGESLIEIDLIITDSEASKETIQE
FEKQGKEIVIASIDYV
>Mature_256_residues
MFTEERREKILELLKKNGRVIAKDLAESFDMSIDSIRRDLSIMEKDGLLKRTHGGAIELARVRNLATKPLKRYSNGSVYE
DAIAKIAASYIQEGDSVFIGGASIHYAMLKYLPETSFTVITNALEIASTLQEYKNIDMYLIGGMVKPSGNMTDTLASELI
SRFSIDLNFSTGDGISLNGISTATPEVAFFSKTVSKIARRNICLAPHNKLGIDYFIKGESLIEIDLIITDSEASKETIQE
FEKQGKEIVIASIDYV

Specific function: Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=254, Percent_Identity=31.1023622047244, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1789519, Length=253, Percent_Identity=24.901185770751, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI226510968, Length=253, Percent_Identity=26.4822134387352, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790635, Length=250, Percent_Identity=24.8, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790753, Length=177, Percent_Identity=29.3785310734463, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1789829, Length=243, Percent_Identity=25.9259259259259, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082344, Length=229, Percent_Identity=25.764192139738, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788069, Length=243, Percent_Identity=26.7489711934156, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787540, Length=191, Percent_Identity=29.8429319371728, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789170, Length=177, Percent_Identity=27.1186440677966, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28378; Mature: 28378

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTEERREKILELLKKNGRVIAKDLAESFDMSIDSIRRDLSIMEKDGLLKRTHGGAIELA
CCCHHHHHHHHHHHHHCCCEEHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCEEHHH
RVRNLATKPLKRYSNGSVYEDAIAKIAASYIQEGDSVFIGGASIHYAMLKYLPETSFTVI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCCCCCHHHH
TNALEIASTLQEYKNIDMYLIGGMVKPSGNMTDTLASELISRFSIDLNFSTGDGISLNGI
HHHHHHHHHHHHHHCCCEEEECCEECCCCCCHHHHHHHHHHHHEEEEEECCCCCEEECCC
STATPEVAFFSKTVSKIARRNICLAPHNKLGIDYFIKGESLIEIDLIITDSEASKETIQE
CCCCCHHHHHHHHHHHHHHCCCEECCCCCCCEEEEECCCCEEEEEEEEECCCCCHHHHHH
FEKQGKEIVIASIDYV
HHHCCCEEEEEEECCC
>Mature Secondary Structure
MFTEERREKILELLKKNGRVIAKDLAESFDMSIDSIRRDLSIMEKDGLLKRTHGGAIELA
CCCHHHHHHHHHHHHHCCCEEHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCEEHHH
RVRNLATKPLKRYSNGSVYEDAIAKIAASYIQEGDSVFIGGASIHYAMLKYLPETSFTVI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCCCCCHHHH
TNALEIASTLQEYKNIDMYLIGGMVKPSGNMTDTLASELISRFSIDLNFSTGDGISLNGI
HHHHHHHHHHHHHHCCCEEEECCEECCCCCCHHHHHHHHHHHHEEEEEECCCCCEEECCC
STATPEVAFFSKTVSKIARRNICLAPHNKLGIDYFIKGESLIEIDLIITDSEASKETIQE
CCCCCHHHHHHHHHHHHHHCCCEECCCCCCCEEEEECCCCEEEEEEEEECCCCCHHHHHH
FEKQGKEIVIASIDYV
HHHCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]