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The map label for this gene is prmA [H]

Identifier: 227080507

GI number: 227080507

Start: 286043

End: 286930

Strand: Reverse

Name: prmA [H]

Synonym: VCM66_0278

Alternate gene names: 227080507

Gene position: 286930-286043 (Counterclockwise)

Preceding gene: 227080508

Following gene: 227080506

Centisome position: 9.92

GC content: 53.38

Gene sequence:

>888_bases
ATGCCTTGGATTCAAATTAAACTCAATGCGACCAACGACAATGCAGAAGCAATTGGCGATATGCTGATGGAAGAAACTGG
TGCTGTGTCAGTCACTTTCCTCGATGCCAAAGATACCCCTGTATTTGAACCTCTACCGGGCGAAACCCGCCTATGGGGTG
ATACCGATGTCGTCGCACTGTACGAAGCGGATATGGATACCTCGCTGATCCTTCAGCAAATCAAAGCCAGCAACATGCTG
GCTGAAGGTTTTGCTCACAAAGTGGAGCAAGTGGAAGATAAGGACTGGGAACGCGAATGGATGGATAACTTCCACCCAAT
GCAATTTGGCCGTCGCCTCTGGATTTGCCCAAGCTGGCGTGAAGTGCCAGACCCACAAGCGGTGAACGTGATGCTCGACC
CGGGCTTGGCTTTTGGTACCGGCACGCACCCAACCACCGCACTGTGCCTAGAGTGGCTGGATAACCTCGACCTGACTGGC
AAAACCGTGATCGATTTTGGTTGTGGCTCGGGCATTCTGGCGATTGCCGCCATCAAGCTTGGTGCCGCAAAAGTGATCGG
GATTGATATCGATCCACAAGCTCTACTCGCGTCCAAAGACAACGCTGCGCGTAACGGCGTGGAAGATCAAATCGAAGTTT
ATCTGCCAAAAGATCAACCCGAAGGCTTGGTGGCTGACGTGGTGGTCGCGAACATTTTGGCTGGCCCACTGCGTGAGCTT
TCGCCCATCATCAAAGGACTCCTGAAGCCCGGTGGCCAACTGGCCATGTCTGGCATTCTGGATACGCAAGCCGAAAGCGT
GGCGGAATTTTACCGTGACGATCTGGAACTTGACCCAATCGCAGAGAAGAGCGAATGGTGCCGCATTTCTGGCCGCAAGC
TAGGCTAG

Upstream 100 bases:

>100_bases
GTTTTGCTTTTTGTTTTAAATCCGCCCACTTTCTGGCCTGAACATCAGTGGCAAATCTGCTACACTCTGCGCCAATCTAA
ACCCGATGAGATCTTAAGCC

Downstream 100 bases:

>100_bases
ATAAGACTTTGCGGCCTAATTGACTGATAAATCGACTATTTGGCAAAACAATTTGCCAATGCTCAAATATTAGTCTTTTC
AGGCATCAAAAAAATGCGTA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MPWIQIKLNATNDNAEAIGDMLMEETGAVSVTFLDAKDTPVFEPLPGETRLWGDTDVVALYEADMDTSLILQQIKASNML
AEGFAHKVEQVEDKDWEREWMDNFHPMQFGRRLWICPSWREVPDPQAVNVMLDPGLAFGTGTHPTTALCLEWLDNLDLTG
KTVIDFGCGSGILAIAAIKLGAAKVIGIDIDPQALLASKDNAARNGVEDQIEVYLPKDQPEGLVADVVVANILAGPLREL
SPIIKGLLKPGGQLAMSGILDTQAESVAEFYRDDLELDPIAEKSEWCRISGRKLG

Sequences:

>Translated_295_residues
MPWIQIKLNATNDNAEAIGDMLMEETGAVSVTFLDAKDTPVFEPLPGETRLWGDTDVVALYEADMDTSLILQQIKASNML
AEGFAHKVEQVEDKDWEREWMDNFHPMQFGRRLWICPSWREVPDPQAVNVMLDPGLAFGTGTHPTTALCLEWLDNLDLTG
KTVIDFGCGSGILAIAAIKLGAAKVIGIDIDPQALLASKDNAARNGVEDQIEVYLPKDQPEGLVADVVVANILAGPLREL
SPIIKGLLKPGGQLAMSGILDTQAESVAEFYRDDLELDPIAEKSEWCRISGRKLG
>Mature_294_residues
PWIQIKLNATNDNAEAIGDMLMEETGAVSVTFLDAKDTPVFEPLPGETRLWGDTDVVALYEADMDTSLILQQIKASNMLA
EGFAHKVEQVEDKDWEREWMDNFHPMQFGRRLWICPSWREVPDPQAVNVMLDPGLAFGTGTHPTTALCLEWLDNLDLTGK
TVIDFGCGSGILAIAAIKLGAAKVIGIDIDPQALLASKDNAARNGVEDQIEVYLPKDQPEGLVADVVVANILAGPLRELS
PIIKGLLKPGGQLAMSGILDTQAESVAEFYRDDLELDPIAEKSEWCRISGRKLG

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=293, Percent_Identity=72.6962457337884, Blast_Score=411, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32255; Mature: 32124

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWIQIKLNATNDNAEAIGDMLMEETGAVSVTFLDAKDTPVFEPLPGETRLWGDTDVVAL
CCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEE
YEADMDTSLILQQIKASNMLAEGFAHKVEQVEDKDWEREWMDNFHPMQFGRRLWICPSWR
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHCCEEEECCCCC
EVPDPQAVNVMLDPGLAFGTGTHPTTALCLEWLDNLDLTGKTVIDFGCGSGILAIAAIKL
CCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
GAAKVIGIDIDPQALLASKDNAARNGVEDQIEVYLPKDQPEGLVADVVVANILAGPLREL
CCEEEEEECCCCHHHHCCCCCHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
SPIIKGLLKPGGQLAMSGILDTQAESVAEFYRDDLELDPIAEKSEWCRISGRKLG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCC
>Mature Secondary Structure 
PWIQIKLNATNDNAEAIGDMLMEETGAVSVTFLDAKDTPVFEPLPGETRLWGDTDVVAL
CEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEE
YEADMDTSLILQQIKASNMLAEGFAHKVEQVEDKDWEREWMDNFHPMQFGRRLWICPSWR
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHCCEEEECCCCC
EVPDPQAVNVMLDPGLAFGTGTHPTTALCLEWLDNLDLTGKTVIDFGCGSGILAIAAIKL
CCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
GAAKVIGIDIDPQALLASKDNAARNGVEDQIEVYLPKDQPEGLVADVVVANILAGPLREL
CCEEEEEECCCCHHHHCCCCCHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
SPIIKGLLKPGGQLAMSGILDTQAESVAEFYRDDLELDPIAEKSEWCRISGRKLG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA