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The map label for this gene is dppC [H]

Identifier: 227080406

GI number: 227080406

Start: 173282

End: 174220

Strand: Direct

Name: dppC [H]

Synonym: VCM66_0172

Alternate gene names: 227080406

Gene position: 173282-174220 (Clockwise)

Preceding gene: 227080405

Following gene: 227080407

Centisome position: 5.99

GC content: 50.27

Gene sequence:

>939_bases
ATGAGTGCAGTATCGATCGCTCCTTCACGTTGGGAGCGCTTTAAGCAGTCCGATTTTCTCTATTATTTCCTGCGCGACAA
AGTGGCGATGAGCAGCTTTGCGGTGTTTGTGCTATTTGTCATCGTGGCAATCAGCGCGCCCTTGATTGCGCCCACCAACC
CGTACGATCTCTCGTCGATTGATATTATGGATGCAGAGCTTCCACCCTCATGGATGGAAGGGGGCAATGAACACTTTTTG
CTGGGCACCGATGAGCAGGGGCGTGACATTTTTTCGACCATTCTGTACGGCTCACGCTTATCACTGACCATCGGCTTTTT
GGCGGTGGGCCTACAACTGACACTTGGCATTGTGATTGGTTTGTCGGCAGGCTATTTCGGTGGCCGAATTGATAGCTTTT
TAATGCGTTTTGCCGATATTCAGCTCTCATTCTCCACCATGATGGTGGCGATCATTGTGTCGGCGATCTTTAAAGCCAGT
TTTGGTGGTGAGTTCTTCAGCCAATATGCGGTGGTGATGTTGGTGGTGATCATCGGTGTGGCGGAATGGCCGCAATACGC
GCGTACGGTGCGCGCTTCGGTGCTGGCGGAGAAGAAAAAAGAGTATGTGGAAGCGGCACGCGTGATGGGCTTTAAAGCGC
CGCGTATCATGTTCCGCCATATTTTGCCCAACTGTTTATCACCAATCTTGGTGATTTCAACGGTACAGGTGGCAAACGCG
ATCATGTCAGAGGCGGCACTCTCCTTCCTTGGCTTAGGATTACCGGTCGATCAGCCGTCACTGGGCTCTCTGATCAGTAT
CGGTTTTACCTACATTTTCTCGGGTGCATGGTGGATAACCGCCTTTCCCGGCATTGTATTGGTATTGCTGGTATTAGTGA
TTAACTTGCTTGGCGATTGGTTGCGTGATGTGTTTAACCCGAAAATTTACAAAGGGTAA

Upstream 100 bases:

>100_bases
TCTTTGTTGGGTTGATCTTTGTCGTGACCAACACGATTGTCGACCTCTTGTATGGCCTGATTAACCCGACCGTCAACCTC
ACTGGCAAAGGAGCTTAACC

Downstream 100 bases:

>100_bases
GTAAATCCGATTGATTTGCTTCACAAACTCTCCATAAACTAAGAGCCGTTTTTGAATGCGGCTCTTTTTTTGCATTTATT
TTTGCTATACCGGATCCCAA

Product: peptide ABC transporter, permease protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSAVSIAPSRWERFKQSDFLYYFLRDKVAMSSFAVFVLFVIVAISAPLIAPTNPYDLSSIDIMDAELPPSWMEGGNEHFL
LGTDEQGRDIFSTILYGSRLSLTIGFLAVGLQLTLGIVIGLSAGYFGGRIDSFLMRFADIQLSFSTMMVAIIVSAIFKAS
FGGEFFSQYAVVMLVVIIGVAEWPQYARTVRASVLAEKKKEYVEAARVMGFKAPRIMFRHILPNCLSPILVISTVQVANA
IMSEAALSFLGLGLPVDQPSLGSLISIGFTYIFSGAWWITAFPGIVLVLLVLVINLLGDWLRDVFNPKIYKG

Sequences:

>Translated_312_residues
MSAVSIAPSRWERFKQSDFLYYFLRDKVAMSSFAVFVLFVIVAISAPLIAPTNPYDLSSIDIMDAELPPSWMEGGNEHFL
LGTDEQGRDIFSTILYGSRLSLTIGFLAVGLQLTLGIVIGLSAGYFGGRIDSFLMRFADIQLSFSTMMVAIIVSAIFKAS
FGGEFFSQYAVVMLVVIIGVAEWPQYARTVRASVLAEKKKEYVEAARVMGFKAPRIMFRHILPNCLSPILVISTVQVANA
IMSEAALSFLGLGLPVDQPSLGSLISIGFTYIFSGAWWITAFPGIVLVLLVLVINLLGDWLRDVFNPKIYKG
>Mature_311_residues
SAVSIAPSRWERFKQSDFLYYFLRDKVAMSSFAVFVLFVIVAISAPLIAPTNPYDLSSIDIMDAELPPSWMEGGNEHFLL
GTDEQGRDIFSTILYGSRLSLTIGFLAVGLQLTLGIVIGLSAGYFGGRIDSFLMRFADIQLSFSTMMVAIIVSAIFKASF
GGEFFSQYAVVMLVVIIGVAEWPQYARTVRASVLAEKKKEYVEAARVMGFKAPRIMFRHILPNCLSPILVISTVQVANAI
MSEAALSFLGLGLPVDQPSLGSLISIGFTYIFSGAWWITAFPGIVLVLLVLVINLLGDWLRDVFNPKIYKG

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=296, Percent_Identity=41.554054054054, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1787760, Length=304, Percent_Identity=30.5921052631579, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787054, Length=297, Percent_Identity=33.3333333333333, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1787498, Length=286, Percent_Identity=34.965034965035, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789889, Length=257, Percent_Identity=32.6848249027237, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788505, Length=241, Percent_Identity=29.8755186721992, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787549, Length=236, Percent_Identity=30.9322033898305, Blast_Score=108, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34315; Mature: 34184

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVSIAPSRWERFKQSDFLYYFLRDKVAMSSFAVFVLFVIVAISAPLIAPTNPYDLSSI
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DIMDAELPPSWMEGGNEHFLLGTDEQGRDIFSTILYGSRLSLTIGFLAVGLQLTLGIVIG
EEECCCCCCHHHCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LSAGYFGGRIDSFLMRFADIQLSFSTMMVAIIVSAIFKASFGGEFFSQYAVVMLVVIIGV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AEWPQYARTVRASVLAEKKKEYVEAARVMGFKAPRIMFRHILPNCLSPILVISTVQVANA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMSEAALSFLGLGLPVDQPSLGSLISIGFTYIFSGAWWITAFPGIVLVLLVLVINLLGDW
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LRDVFNPKIYKG
HHHHCCCCCCCC
>Mature Secondary Structure 
SAVSIAPSRWERFKQSDFLYYFLRDKVAMSSFAVFVLFVIVAISAPLIAPTNPYDLSSI
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC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HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]