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The map label for this gene is dppB [H]

Identifier: 227080405

GI number: 227080405

Start: 172251

End: 173279

Strand: Direct

Name: dppB [H]

Synonym: VCM66_0171

Alternate gene names: 227080405

Gene position: 172251-173279 (Clockwise)

Preceding gene: 227080404

Following gene: 227080406

Centisome position: 5.96

GC content: 50.24

Gene sequence:

>1029_bases
TTGGCGCTTCATCGCGCCCACAGATTCACATGGAAAGTTAAGGGGCAAGGAATGTTTTCGTTTCTGGTCAAGCGCCTGTA
TCAGGCACTGATAGTGATGTTTGTGATCAGTTTGGTAGCGTTTGCCATTCAGGACAACCTGGGTGATCCGCTGCGCGAGC
TTGTGGGTCAGTCCGTTTCTGAAGCTGAGCGTCAAGCACTGCGTGACGAATTAGGCCTCAATGATCCCTTCATTATTAAA
TATTCTCGTTTTGTAACTGCGGCGGTGCAGGGGGATTTAGGGACTTCCTATTTCTTTAAGCGTCCGGCGCTGGAAGTGAT
CTTCGATAAGCTGGTGGCGACACTGGAGCTGGTGTTTGGTGCTACGTTGATCATCATAGTGTTTTCAATCCCGCTTGGGG
TCTATTCGGCGATTCATCCGAAAAGCTTGTTTACCAAGATAGTGATGGCGGGCAGCAGCATCGGCATTTCGATCCCGGTC
TTTTTAACCGCGATCATGCTGATGTATGTCTTCTCGATTGAGTTAGGTTGGTTGCCGTCCTATGGTCGTGGCGAAACCGT
TAACCTACTGGGCTGGGAGTCCGGATTCTTTACCCTCGATGGCTTGCGCCATCTGGTATTGCCCTCTATCGCACTGGCTT
CCATTATGTTGCCGCTGTTCATCCGCCTCGTGCGCTCGGAAATGCTCGAAGTACTGAGCTCGGAATACATCAAGTTTGCG
CAAGCCAAAGGTTTGCCACTCAACAAAATCTATTACCAACATGCGCTGAAAAACACCATGTTGCCGGTATTGACCGTGGG
TGGGGTGCAGATTGGTACTATGGTGGCCTACACCATTTTGACCGAAACCGTATTCCAGTGGCCGGGAACGGGCTTCTTGT
TTTTAGAGGCGATTAACCGTGTGGATACGCCACTTATCACGGCCTACGTCATCTTTGTTGGGTTGATCTTTGTCGTGACC
AACACGATTGTCGACCTCTTGTATGGCCTGATTAACCCGACCGTCAACCTCACTGGCAAAGGAGCTTAA

Upstream 100 bases:

>100_bases
CGGACCACTCTGCTCTGTAGGCGTTGGTCTACAGAGCTTCTCTTCGGGTACAGGGTTTTGTTTCAGTCGGGCCCCGTACC
CTTTTTCAGACTGAAAGGTT

Downstream 100 bases:

>100_bases
CCATGAGTGCAGTATCGATCGCTCCTTCACGTTGGGAGCGCTTTAAGCAGTCCGATTTTCTCTATTATTTCCTGCGCGAC
AAAGTGGCGATGAGCAGCTT

Product: peptide ABC transporter, permease protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MALHRAHRFTWKVKGQGMFSFLVKRLYQALIVMFVISLVAFAIQDNLGDPLRELVGQSVSEAERQALRDELGLNDPFIIK
YSRFVTAAVQGDLGTSYFFKRPALEVIFDKLVATLELVFGATLIIIVFSIPLGVYSAIHPKSLFTKIVMAGSSIGISIPV
FLTAIMLMYVFSIELGWLPSYGRGETVNLLGWESGFFTLDGLRHLVLPSIALASIMLPLFIRLVRSEMLEVLSSEYIKFA
QAKGLPLNKIYYQHALKNTMLPVLTVGGVQIGTMVAYTILTETVFQWPGTGFLFLEAINRVDTPLITAYVIFVGLIFVVT
NTIVDLLYGLINPTVNLTGKGA

Sequences:

>Translated_342_residues
MALHRAHRFTWKVKGQGMFSFLVKRLYQALIVMFVISLVAFAIQDNLGDPLRELVGQSVSEAERQALRDELGLNDPFIIK
YSRFVTAAVQGDLGTSYFFKRPALEVIFDKLVATLELVFGATLIIIVFSIPLGVYSAIHPKSLFTKIVMAGSSIGISIPV
FLTAIMLMYVFSIELGWLPSYGRGETVNLLGWESGFFTLDGLRHLVLPSIALASIMLPLFIRLVRSEMLEVLSSEYIKFA
QAKGLPLNKIYYQHALKNTMLPVLTVGGVQIGTMVAYTILTETVFQWPGTGFLFLEAINRVDTPLITAYVIFVGLIFVVT
NTIVDLLYGLINPTVNLTGKGA
>Mature_341_residues
ALHRAHRFTWKVKGQGMFSFLVKRLYQALIVMFVISLVAFAIQDNLGDPLRELVGQSVSEAERQALRDELGLNDPFIIKY
SRFVTAAVQGDLGTSYFFKRPALEVIFDKLVATLELVFGATLIIIVFSIPLGVYSAIHPKSLFTKIVMAGSSIGISIPVF
LTAIMLMYVFSIELGWLPSYGRGETVNLLGWESGFFTLDGLRHLVLPSIALASIMLPLFIRLVRSEMLEVLSSEYIKFAQ
AKGLPLNKIYYQHALKNTMLPVLTVGGVQIGTMVAYTILTETVFQWPGTGFLFLEAINRVDTPLITAYVIFVGLIFVVTN
TIVDLLYGLINPTVNLTGKGA

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=35.9050445103858, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1787053, Length=320, Percent_Identity=31.25, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1789888, Length=323, Percent_Identity=30.6501547987616, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787761, Length=335, Percent_Identity=35.2238805970149, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787497, Length=323, Percent_Identity=29.7213622291022, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787550, Length=260, Percent_Identity=31.5384615384615, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788504, Length=275, Percent_Identity=28.3636363636364, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37883; Mature: 37751

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALHRAHRFTWKVKGQGMFSFLVKRLYQALIVMFVISLVAFAIQDNLGDPLRELVGQSVS
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHH
EAERQALRDELGLNDPFIIKYSRFVTAAVQGDLGTSYFFKRPALEVIFDKLVATLELVFG
HHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
ATLIIIVFSIPLGVYSAIHPKSLFTKIVMAGSSIGISIPVFLTAIMLMYVFSIELGWLPS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
YGRGETVNLLGWESGFFTLDGLRHLVLPSIALASIMLPLFIRLVRSEMLEVLSSEYIKFA
CCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAKGLPLNKIYYQHALKNTMLPVLTVGGVQIGTMVAYTILTETVFQWPGTGFLFLEAINR
HHCCCCHHHHHHHHHHHHHCHHHHEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VDTPLITAYVIFVGLIFVVTNTIVDLLYGLINPTVNLTGKGA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ALHRAHRFTWKVKGQGMFSFLVKRLYQALIVMFVISLVAFAIQDNLGDPLRELVGQSVS
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHH
EAERQALRDELGLNDPFIIKYSRFVTAAVQGDLGTSYFFKRPALEVIFDKLVATLELVFG
HHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
ATLIIIVFSIPLGVYSAIHPKSLFTKIVMAGSSIGISIPVFLTAIMLMYVFSIELGWLPS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
YGRGETVNLLGWESGFFTLDGLRHLVLPSIALASIMLPLFIRLVRSEMLEVLSSEYIKFA
CCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAKGLPLNKIYYQHALKNTMLPVLTVGGVQIGTMVAYTILTETVFQWPGTGFLFLEAINR
HHCCCCHHHHHHHHHHHHHCHHHHEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VDTPLITAYVIFVGLIFVVTNTIVDLLYGLINPTVNLTGKGA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9680333 [H]