Click here to switch to the map view.

The map label for this gene is xerC [H]

Identifier: 226950799

GI number: 226950799

Start: 3853322

End: 3853921

Strand: Direct

Name: xerC [H]

Synonym: CLM_3810

Alternate gene names: 226950799

Gene position: 3853322-3853921 (Clockwise)

Preceding gene: 226950789

Following gene: 226950804

Centisome position: 92.73

GC content: 28.5

Gene sequence:

>600_bases
ATGCCAGAAAATTCTAGCAATAAGATGAAGTACTTAACACAACAAGAAGCAATTAGACTTTTTAATGCAATTATATTTTC
AGATAATTCTCATGCCGTTAGGGATTTAGCATTGTTTAGAGTAGCTTATAGATGTGGTTTAAGAGCCTCTGAAATTTCTC
TTATAAAGTTAGATGATTACAACGCAGATAAAGGAGATCTTTACTGCAAAAGATTAAAAGGTAGTAATAACAATACAATA
AGACTTGATGCTACAACTAAAAAAGCTCTTGATACATATATAAGGGATTATAAAATATTCTGTAATTCTGAAACATTGTT
TAAAAGTCAAAAAAACAATCCTATCTCTCGTCAAACGCTAGATTATTTAATGAAAAAATATTGTAAAATTGCTAATATTA
GTGATAAAAGTAAACATCATTTTCATACACTTAAACACACAACTGCTGTTCATTTAGCAGAGTCAGAAATGGATATTAAA
GAGCTTCAATGGTGGCTTGGACATAAATCTGTTTCTAACACTGAAATTTATTTTCAATTTACTACAAAACAACAAGAAAA
AATGTATATGAAACTTGAAGAAACAAGCGAAATGGTATAG

Upstream 100 bases:

>100_bases
TTAAATCGAAATATTTTTATAAAAAGTTTGATTATCTTCTAAGTTTTGGTATAATTAATTATACAAAATATTTTGTATAA
TTCTGTGGAGGAAATTTACT

Downstream 100 bases:

>100_bases
GCATTGTTATATTCCACATATTTACAATGTAAAAAGTTATTCATATTTTTAATATATTTGTACTAACACTGAGCTATTCC
CTTGAAGATATAAAAAGCTT

Product: phage integrase family site-specific recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MPENSSNKMKYLTQQEAIRLFNAIIFSDNSHAVRDLALFRVAYRCGLRASEISLIKLDDYNADKGDLYCKRLKGSNNNTI
RLDATTKKALDTYIRDYKIFCNSETLFKSQKNNPISRQTLDYLMKKYCKIANISDKSKHHFHTLKHTTAVHLAESEMDIK
ELQWWLGHKSVSNTEIYFQFTTKQQEKMYMKLEETSEMV

Sequences:

>Translated_199_residues
MPENSSNKMKYLTQQEAIRLFNAIIFSDNSHAVRDLALFRVAYRCGLRASEISLIKLDDYNADKGDLYCKRLKGSNNNTI
RLDATTKKALDTYIRDYKIFCNSETLFKSQKNNPISRQTLDYLMKKYCKIANISDKSKHHFHTLKHTTAVHLAESEMDIK
ELQWWLGHKSVSNTEIYFQFTTKQQEKMYMKLEETSEMV
>Mature_198_residues
PENSSNKMKYLTQQEAIRLFNAIIFSDNSHAVRDLALFRVAYRCGLRASEISLIKLDDYNADKGDLYCKRLKGSNNNTIR
LDATTKKALDTYIRDYKIFCNSETLFKSQKNNPISRQTLDYLMKKYCKIANISDKSKHHFHTLKHTTAVHLAESEMDIKE
LQWWLGHKSVSNTEIYFQFTTKQQEKMYMKLEETSEMV

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=194, Percent_Identity=27.8350515463918, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790767, Length=172, Percent_Identity=30.2325581395349, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790768, Length=174, Percent_Identity=25.2873563218391, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 23356; Mature: 23225

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPENSSNKMKYLTQQEAIRLFNAIIFSDNSHAVRDLALFRVAYRCGLRASEISLIKLDDY
CCCCCCCHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
NADKGDLYCKRLKGSNNNTIRLDATTKKALDTYIRDYKIFCNSETLFKSQKNNPISRQTL
CCCCHHHEEEEECCCCCCEEEEECCHHHHHHHHHHHEEEEECCHHHHHCCCCCCCHHHHH
DYLMKKYCKIANISDKSKHHFHTLKHTTAVHLAESEMDIKELQWWLGHKSVSNTEIYFQF
HHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCCCCCCCEEEEEE
TTKQQEKMYMKLEETSEMV
CCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PENSSNKMKYLTQQEAIRLFNAIIFSDNSHAVRDLALFRVAYRCGLRASEISLIKLDDY
CCCCCCHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
NADKGDLYCKRLKGSNNNTIRLDATTKKALDTYIRDYKIFCNSETLFKSQKNNPISRQTL
CCCCHHHEEEEECCCCCCEEEEECCHHHHHHHHHHHEEEEECCHHHHHCCCCCCCHHHHH
DYLMKKYCKIANISDKSKHHFHTLKHTTAVHLAESEMDIKELQWWLGHKSVSNTEIYFQF
HHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCCCCCCCEEEEEE
TTKQQEKMYMKLEETSEMV
CCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]