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The map label for this gene is lldD [H]

Identifier: 226950550

GI number: 226950550

Start: 3559159

End: 3560172

Strand: Reverse

Name: lldD [H]

Synonym: CLM_3526

Alternate gene names: 226950550

Gene position: 3560172-3559159 (Counterclockwise)

Preceding gene: 226950551

Following gene: 226950549

Centisome position: 85.68

GC content: 33.23

Gene sequence:

>1014_bases
ATGAATTATAAAGATATATTAAAAAATGCCCGTGAAAATTTAAATGGAAGTTGTAGAGTTTGCAGAGTATGTAATGGGAA
AGCCTGTAGTGGTGAAGTACCTGGTATGGGCGGTAAAGGTACAGGAGATGCATTTACTATAAATATAGATGCATTAGATT
CTTATAAATTAAATATGAGATTGATTCATGATGCCAAGAATCCAGATATAAGTGTAGAATTATTTGGAAGAAAAATGGAC
ATGCCTATTTTTGCAGCACCAGTATCAGGAACTACTTTAAATATGGGTGGTAAGTTTACAGAAGAAGAATATATATCTTG
GGTAATTGGTGGATGTAGAGATTCAGGTATATATCCAATGGTAGGAGATACTGCAGTAGATTCATTCTTAATTACCAATT
TAGATGAGTTAAAAAAGTTTAATGGAGAAGGAATTGTAATAATAAAGCCTTGGGAAAATGATAATGTAATAAGTAAAATA
AAATTAGCAGAAGAAGCAGGAGCTTATGCTGTTGGCATGGATATAGATGCAGCAGGACTTATAACTTTAGCTCTTCATGG
AAAACCAGTGGGTCCAAAAACTGTAGAAGAAATAAAAGAAATAGTGAAAAGTACTAAATTACCTTTTATATTAAAAGGAA
TAATGACCGTTGAAGATGCTAAATTAGCCGTAGAAGCTGGGGTAGATGCAATTGTAGTATCAAATCATGGTGGTAGAGTT
TTAGACCAAACTCCAGGTGTAGCAGATGTATTACCTGAAATCGCAGAAGCGGTTAAAGGAAAAGTAACCATATTAGCAGA
TGGTGGTGTAAGAACTGGTGTAGATGTACTAAAAATGATAGCTTTAGGGGCAGATGCAGTATTAATAGGAAGACCCTTTG
TAAAAGCTTCCTTTGGAGGAGAAAGAGAAGGGGTAAAAATTTATGTCGAAAATTTAAAAAGTGAATTAAAATCAGCTATG
GTTTTAACAGGATGTAACAGTATAAAGGATATAGATGAAAAGATAATATATTAG

Upstream 100 bases:

>100_bases
TTAAAAATGTTGATATGGCTGTGGAACGTTTACACACAGCATGATTAGTTATAAAATTATATTAATAATCTAATTTTATA
AAATAAGGAGGTATTACAAA

Downstream 100 bases:

>100_bases
TTTATCCTTTAAATAGATACATATTATTGTATTCCTACTATGATAAAATATATTATATATTTGGATAGCCATGTGTTGAT
TTACAAAGAATAATTTATAT

Product: dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MNYKDILKNARENLNGSCRVCRVCNGKACSGEVPGMGGKGTGDAFTINIDALDSYKLNMRLIHDAKNPDISVELFGRKMD
MPIFAAPVSGTTLNMGGKFTEEEYISWVIGGCRDSGIYPMVGDTAVDSFLITNLDELKKFNGEGIVIIKPWENDNVISKI
KLAEEAGAYAVGMDIDAAGLITLALHGKPVGPKTVEEIKEIVKSTKLPFILKGIMTVEDAKLAVEAGVDAIVVSNHGGRV
LDQTPGVADVLPEIAEAVKGKVTILADGGVRTGVDVLKMIALGADAVLIGRPFVKASFGGEREGVKIYVENLKSELKSAM
VLTGCNSIKDIDEKIIY

Sequences:

>Translated_337_residues
MNYKDILKNARENLNGSCRVCRVCNGKACSGEVPGMGGKGTGDAFTINIDALDSYKLNMRLIHDAKNPDISVELFGRKMD
MPIFAAPVSGTTLNMGGKFTEEEYISWVIGGCRDSGIYPMVGDTAVDSFLITNLDELKKFNGEGIVIIKPWENDNVISKI
KLAEEAGAYAVGMDIDAAGLITLALHGKPVGPKTVEEIKEIVKSTKLPFILKGIMTVEDAKLAVEAGVDAIVVSNHGGRV
LDQTPGVADVLPEIAEAVKGKVTILADGGVRTGVDVLKMIALGADAVLIGRPFVKASFGGEREGVKIYVENLKSELKSAM
VLTGCNSIKDIDEKIIY
>Mature_337_residues
MNYKDILKNARENLNGSCRVCRVCNGKACSGEVPGMGGKGTGDAFTINIDALDSYKLNMRLIHDAKNPDISVELFGRKMD
MPIFAAPVSGTTLNMGGKFTEEEYISWVIGGCRDSGIYPMVGDTAVDSFLITNLDELKKFNGEGIVIIKPWENDNVISKI
KLAEEAGAYAVGMDIDAAGLITLALHGKPVGPKTVEEIKEIVKSTKLPFILKGIMTVEDAKLAVEAGVDAIVVSNHGGRV
LDQTPGVADVLPEIAEAVKGKVTILADGGVRTGVDVLKMIALGADAVLIGRPFVKASFGGEREGVKIYVENLKSELKSAM
VLTGCNSIKDIDEKIIY

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=344, Percent_Identity=31.1046511627907, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI54234014, Length=132, Percent_Identity=48.4848484848485, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI7705393, Length=132, Percent_Identity=48.4848484848485, Blast_Score=126, Evalue=3e-29,
Organism=Escherichia coli, GI1790033, Length=141, Percent_Identity=48.2269503546099, Blast_Score=122, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI193208036, Length=135, Percent_Identity=45.1851851851852, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6323587, Length=338, Percent_Identity=29.8816568047337, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281363140, Length=346, Percent_Identity=27.4566473988439, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI78707190, Length=346, Percent_Identity=27.4566473988439, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI78707188, Length=346, Percent_Identity=27.4566473988439, Blast_Score=107, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 35949; Mature: 35949

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYKDILKNARENLNGSCRVCRVCNGKACSGEVPGMGGKGTGDAFTINIDALDSYKLNMR
CCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEE
LIHDAKNPDISVELFGRKMDMPIFAAPVSGTTLNMGGKFTEEEYISWVIGGCRDSGIYPM
EEECCCCCCEEEEEECCCCCCCEEEECCCCCEEECCCCCCHHHHHHHHEECCCCCCCCCE
VGDTAVDSFLITNLDELKKFNGEGIVIIKPWENDNVISKIKLAEEAGAYAVGMDIDAAGL
ECCHHHHHHHHCCHHHHHHCCCCEEEEEECCCCCCHHHHEEEHHHCCCEEEECCCCCCCE
ITLALHGKPVGPKTVEEIKEIVKSTKLPFILKGIMTVEDAKLAVEAGVDAIVVSNHGGRV
EEEEECCCCCCHHHHHHHHHHHHHCCCCCEEHHHHEECCCCEEEECCCCEEEEECCCCEE
LDQTPGVADVLPEIAEAVKGKVTILADGGVRTGVDVLKMIALGADAVLIGRPFVKASFGG
ECCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCEEEECCCC
EREGVKIYVENLKSELKSAMVLTGCNSIKDIDEKIIY
CCCCCEEEHHHHHHHHHHHEEEECCCHHHHHHHHHCC
>Mature Secondary Structure
MNYKDILKNARENLNGSCRVCRVCNGKACSGEVPGMGGKGTGDAFTINIDALDSYKLNMR
CCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEE
LIHDAKNPDISVELFGRKMDMPIFAAPVSGTTLNMGGKFTEEEYISWVIGGCRDSGIYPM
EEECCCCCCEEEEEECCCCCCCEEEECCCCCEEECCCCCCHHHHHHHHEECCCCCCCCCE
VGDTAVDSFLITNLDELKKFNGEGIVIIKPWENDNVISKIKLAEEAGAYAVGMDIDAAGL
ECCHHHHHHHHCCHHHHHHCCCCEEEEEECCCCCCHHHHEEEHHHCCCEEEECCCCCCCE
ITLALHGKPVGPKTVEEIKEIVKSTKLPFILKGIMTVEDAKLAVEAGVDAIVVSNHGGRV
EEEEECCCCCCHHHHHHHHHHHHHCCCCCEEHHHHEECCCCEEEECCCCEEEEECCCCEE
LDQTPGVADVLPEIAEAVKGKVTILADGGVRTGVDVLKMIALGADAVLIGRPFVKASFGG
ECCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCEEEECCCC
EREGVKIYVENLKSELKSAMVLTGCNSIKDIDEKIIY
CCCCCEEEHHHHHHHHHHHEEEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA