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The map label for this gene is hflX [H]

Identifier: 226950509

GI number: 226950509

Start: 3504758

End: 3506542

Strand: Reverse

Name: hflX [H]

Synonym: CLM_3485

Alternate gene names: 226950509

Gene position: 3506542-3504758 (Counterclockwise)

Preceding gene: 226950511

Following gene: 226950508

Centisome position: 84.39

GC content: 27.9

Gene sequence:

>1785_bases
ATGATATATGGTAATATTGATGGAATAAGAAAAACTGTTTTAGAGGAATTAGAACAAATATATGAAATGAAAATAGAAAA
GAATGACATCGTTAACGAAGAACTAATGAATGTATTATGCAAATTAACAGAACAGTTAAACAGAGAAATAAGTGTAGGAA
TATCTAGAAAAGGTGGTATAATAGCAGTTTCCGTAGGAGATAGTACAACTGTAGAAATGCCAGAGGTGGAAATCAAAACC
AATAAGCTTTCAAGTATAAGAATTGTTCATACTCACCCAAATGGTAATCCTAAACTTTCTTCAGTAGATTTATCTGCATT
ATTAAAATTGAAATTAGATTGTATGGTAGCTATAGGAGTAGAGTATGAAAAGATAACAGGATTTGGTGTGGCTTTTTGTA
CTATGGAGGATAGTAAACTAAGTATAGAGGAAAAGTATTTTAAAGATATAAATAGCCTATTAGACTTTAATTTATTAAAT
GAAATAAATCATATAGAACAAAATTTGAAAAATGAAGAATTAGAAGATCAGGAAGAAGAAAAGGTTATACTTGTTAGTAT
TGATGATGAAGAAAGCATAGATGAATTAGAAGAATTAGCTAAGGCTTGTAATCTAAAAGTTGTAGAAAAAGTTTTACAAA
ATAAAAATAAAATTGATTCAGCCTATTATATAGGTACAGGTAAGGTAGGAGAAATAGCTTTAATAAGGCAGGCCTTAAAT
GCAGATGTGGTAATATTTGATGATGAACTTTCTGCTTCTCAAATAAGAAATTTAGAAGAATCTATAGGAACTAAAGTAAT
AGATAGAAATACATTAATATTAGATATATTTGCAAGAAGAGCAAAAAGTAAAGAAAGTAAAATACAGGTAGAACTTGCAC
AATTAAAATATAGATTAGCAAGATTAACAGGTTTAGGATTGGTTTTATCAAGAACAGGTGGAGGAATAGGTACAAAAGGA
CCAGGTGAAAAAAAGCTAGAGACAGATAAAAGGCATATAAAGGAAAGAATTTATGATTTAAAAAAAGAATTATATAAAAT
AAAAAAAGTTAGGGAAACTCAAAGAAGTAAAAGAAATGATATACCTAAGGTTTCTTTAGTAGGGTATACTAATGCAGGCA
AATCTACATTAAGAAACAAATTATGTGATACAGGAATAGCTAATGCACAAAATAAAGAAAAGGTTTTTGAGGCAGATATG
TTATTTGCTACATTAGACATCACAACTAGAGCAATATCATTACCTAACAATGAAATTATAACATTGACGGATACGGTAGG
TTTTGTAAGAAAGCTTCCTCATGAATTAGTAGAAGCTTTTAAATCCACATTAGAAGAAGTTATTTACTCTGATTTACTTC
TACATGTAATAGACATTTCCTCGGATACAGCAGAAAAACAAATAGATGCAGTTAATAATGTATTAGAGGAATTAGGAACA
GAAAATAAACAAATAATATTAGTATTTAATAAAATAGATAAAGTTTCAATGGAAAGATTAAATTATTTCAGAGATAAATT
TAAAGATGAAAAGGTTATAGAAATATCCGCTAGATTAGGTATAAATCTTGAAGACTTGTTAAAGCTAATAGAGGAAACAT
TGCCATATAAATTAGCAGAAGTAGAGTATATAATTCCTTACGATAAACAAAAAACAGTAGCATTTTTGCATAGAAACAGT
AAAATAATGGAAGAAGAATATAGAGAAAAAGGAACTTACATTAAAACAAAGGTAGATACGGAAGTTTATAATAAGTGCCA
GGAATTTCTCATTAATAAAGAATAA

Upstream 100 bases:

>100_bases
TATTGTTTTTATAGTATAAAATTATATGAAAGTTGTCAAGGTATAGAGTAAAGCCTAATAAATCTTTTTATTATAATTTG
TATAGAAAGGTAGATATTAA

Downstream 100 bases:

>100_bases
AAAATATACTTTTTAAATTGTTCATTAAAAAGTAACAAATAGAAAAAGGAATTATTAATGAGGTGTAGAATATAATAATT
ACAAAATAATTATTATTAAT

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MIYGNIDGIRKTVLEELEQIYEMKIEKNDIVNEELMNVLCKLTEQLNREISVGISRKGGIIAVSVGDSTTVEMPEVEIKT
NKLSSIRIVHTHPNGNPKLSSVDLSALLKLKLDCMVAIGVEYEKITGFGVAFCTMEDSKLSIEEKYFKDINSLLDFNLLN
EINHIEQNLKNEELEDQEEEKVILVSIDDEESIDELEELAKACNLKVVEKVLQNKNKIDSAYYIGTGKVGEIALIRQALN
ADVVIFDDELSASQIRNLEESIGTKVIDRNTLILDIFARRAKSKESKIQVELAQLKYRLARLTGLGLVLSRTGGGIGTKG
PGEKKLETDKRHIKERIYDLKKELYKIKKVRETQRSKRNDIPKVSLVGYTNAGKSTLRNKLCDTGIANAQNKEKVFEADM
LFATLDITTRAISLPNNEIITLTDTVGFVRKLPHELVEAFKSTLEEVIYSDLLLHVIDISSDTAEKQIDAVNNVLEELGT
ENKQIILVFNKIDKVSMERLNYFRDKFKDEKVIEISARLGINLEDLLKLIEETLPYKLAEVEYIIPYDKQKTVAFLHRNS
KIMEEEYREKGTYIKTKVDTEVYNKCQEFLINKE

Sequences:

>Translated_594_residues
MIYGNIDGIRKTVLEELEQIYEMKIEKNDIVNEELMNVLCKLTEQLNREISVGISRKGGIIAVSVGDSTTVEMPEVEIKT
NKLSSIRIVHTHPNGNPKLSSVDLSALLKLKLDCMVAIGVEYEKITGFGVAFCTMEDSKLSIEEKYFKDINSLLDFNLLN
EINHIEQNLKNEELEDQEEEKVILVSIDDEESIDELEELAKACNLKVVEKVLQNKNKIDSAYYIGTGKVGEIALIRQALN
ADVVIFDDELSASQIRNLEESIGTKVIDRNTLILDIFARRAKSKESKIQVELAQLKYRLARLTGLGLVLSRTGGGIGTKG
PGEKKLETDKRHIKERIYDLKKELYKIKKVRETQRSKRNDIPKVSLVGYTNAGKSTLRNKLCDTGIANAQNKEKVFEADM
LFATLDITTRAISLPNNEIITLTDTVGFVRKLPHELVEAFKSTLEEVIYSDLLLHVIDISSDTAEKQIDAVNNVLEELGT
ENKQIILVFNKIDKVSMERLNYFRDKFKDEKVIEISARLGINLEDLLKLIEETLPYKLAEVEYIIPYDKQKTVAFLHRNS
KIMEEEYREKGTYIKTKVDTEVYNKCQEFLINKE
>Mature_594_residues
MIYGNIDGIRKTVLEELEQIYEMKIEKNDIVNEELMNVLCKLTEQLNREISVGISRKGGIIAVSVGDSTTVEMPEVEIKT
NKLSSIRIVHTHPNGNPKLSSVDLSALLKLKLDCMVAIGVEYEKITGFGVAFCTMEDSKLSIEEKYFKDINSLLDFNLLN
EINHIEQNLKNEELEDQEEEKVILVSIDDEESIDELEELAKACNLKVVEKVLQNKNKIDSAYYIGTGKVGEIALIRQALN
ADVVIFDDELSASQIRNLEESIGTKVIDRNTLILDIFARRAKSKESKIQVELAQLKYRLARLTGLGLVLSRTGGGIGTKG
PGEKKLETDKRHIKERIYDLKKELYKIKKVRETQRSKRNDIPKVSLVGYTNAGKSTLRNKLCDTGIANAQNKEKVFEADM
LFATLDITTRAISLPNNEIITLTDTVGFVRKLPHELVEAFKSTLEEVIYSDLLLHVIDISSDTAEKQIDAVNNVLEELGT
ENKQIILVFNKIDKVSMERLNYFRDKFKDEKVIEISARLGINLEDLLKLIEETLPYKLAEVEYIIPYDKQKTVAFLHRNS
KIMEEEYREKGTYIKTKVDTEVYNKCQEFLINKE

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=221, Percent_Identity=36.6515837104072, Blast_Score=123, Evalue=6e-28,
Organism=Homo sapiens, GI310133116, Length=221, Percent_Identity=36.6515837104072, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI310124269, Length=212, Percent_Identity=36.7924528301887, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI310124267, Length=212, Percent_Identity=36.7924528301887, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI310124171, Length=212, Percent_Identity=36.7924528301887, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI310124169, Length=212, Percent_Identity=36.7924528301887, Blast_Score=120, Evalue=4e-27,
Organism=Escherichia coli, GI1790615, Length=400, Percent_Identity=39.5, Blast_Score=266, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17561038, Length=291, Percent_Identity=31.9587628865979, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24650079, Length=360, Percent_Identity=30.5555555555556, Blast_Score=118, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 67605; Mature: 67605

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGNIDGIRKTVLEELEQIYEMKIEKNDIVNEELMNVLCKLTEQLNREISVGISRKGGI
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCE
IAVSVGDSTTVEMPEVEIKTNKLSSIRIVHTHPNGNPKLSSVDLSALLKLKLDCMVAIGV
EEEECCCCCEEECCCEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHEEEEEECC
EYEKITGFGVAFCTMEDSKLSIEEKYFKDINSLLDFNLLNEINHIEQNLKNEELEDQEEE
CHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KVILVSIDDEESIDELEELAKACNLKVVEKVLQNKNKIDSAYYIGTGKVGEIALIRQALN
CEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHC
ADVVIFDDELSASQIRNLEESIGTKVIDRNTLILDIFARRAKSKESKIQVELAQLKYRLA
CCEEEECCCCCHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
RLTGLGLVLSRTGGGIGTKGPGEKKLETDKRHIKERIYDLKKELYKIKKVRETQRSKRND
HHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IPKVSLVGYTNAGKSTLRNKLCDTGIANAQNKEKVFEADMLFATLDITTRAISLPNNEII
CCCEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEEHHHEEEECCCCCEE
TLTDTVGFVRKLPHELVEAFKSTLEEVIYSDLLLHVIDISSDTAEKQIDAVNNVLEELGT
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
ENKQIILVFNKIDKVSMERLNYFRDKFKDEKVIEISARLGINLEDLLKLIEETLPYKLAE
CCCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEHHHCCCCHHHHHHHHHHHCCCEECC
VEYIIPYDKQKTVAFLHRNSKIMEEEYREKGTYIKTKVDTEVYNKCQEFLINKE
EEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIYGNIDGIRKTVLEELEQIYEMKIEKNDIVNEELMNVLCKLTEQLNREISVGISRKGGI
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCE
IAVSVGDSTTVEMPEVEIKTNKLSSIRIVHTHPNGNPKLSSVDLSALLKLKLDCMVAIGV
EEEECCCCCEEECCCEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHEEEEEECC
EYEKITGFGVAFCTMEDSKLSIEEKYFKDINSLLDFNLLNEINHIEQNLKNEELEDQEEE
CHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KVILVSIDDEESIDELEELAKACNLKVVEKVLQNKNKIDSAYYIGTGKVGEIALIRQALN
CEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHC
ADVVIFDDELSASQIRNLEESIGTKVIDRNTLILDIFARRAKSKESKIQVELAQLKYRLA
CCEEEECCCCCHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
RLTGLGLVLSRTGGGIGTKGPGEKKLETDKRHIKERIYDLKKELYKIKKVRETQRSKRND
HHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IPKVSLVGYTNAGKSTLRNKLCDTGIANAQNKEKVFEADMLFATLDITTRAISLPNNEII
CCCEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEEHHHEEEECCCCCEE
TLTDTVGFVRKLPHELVEAFKSTLEEVIYSDLLLHVIDISSDTAEKQIDAVNNVLEELGT
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
ENKQIILVFNKIDKVSMERLNYFRDKFKDEKVIEISARLGINLEDLLKLIEETLPYKLAE
CCCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEHHHCCCCHHHHHHHHHHHCCCEECC
VEYIIPYDKQKTVAFLHRNSKIMEEEYREKGTYIKTKVDTEVYNKCQEFLINKE
EEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]