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The map label for this gene is coaE [H]

Identifier: 226950436

GI number: 226950436

Start: 3439554

End: 3440192

Strand: Reverse

Name: coaE [H]

Synonym: CLM_3410

Alternate gene names: 226950436

Gene position: 3440192-3439554 (Counterclockwise)

Preceding gene: 226950437

Following gene: 226950435

Centisome position: 82.79

GC content: 25.51

Gene sequence:

>639_bases
ATGTATTGCTTAAAAAGTATTTTTAAAATTGGTCTTACAGGTGGTATAGGTGCTGGTAAAAGTACTATATCAGAAATGAT
AAAAGAAAAAAATATACCAGTAATAGATGCGGATAAAATAAGCAGAGAGGTATTAAAGTTATATCCTGAAATTTTAATAA
GGATAAAAGAAGTTTTTGGTAAAGAATTTTTAGATGATAATGGTGATTTAAAAAGAAGAGAGTTTGGCAGTTATATATTT
AAAAATAAAAATAAAAGAATAGAATATGAAAATATAATAATGCCTTATATAAAAAAAGAAACCTTTAAAAGAATAAAAGT
ATTAGAGGAAAATAAAGAATCAATTTGTGTATTAGATGCTCCTACACTAATAGAACAGGGTTTATACAAATATATGGATA
TAAATATATTAGTTTGGGTGGATAAAGATACACAAATAAATAGGGTTGTAAAAAGAGATGGCTTAAATAGAAGTGAAGTT
ACAAATAGAATAAATTCTCAAATGCCTATGGAAGAGAAAAAGAAGTTTGTAGATTATATGATAGATAATTCTAAAGATAT
AGAAAATACAAAGAGTGAACTAGATAAGATTTTTATGGAAGTAATGATTAAAGCAAAGCAGAAGGGGGGAGTGCTCTAA

Upstream 100 bases:

>100_bases
TAAAAAAAGAAATGGAACAGGTTTTAGAATTAAAAGTTGGGTTAGACGTGGATATAAACATAGGTAATAATTGGTATGAA
GCAAAGTAGGGAGTTGTTTT

Downstream 100 bases:

>100_bases
TATTAGGGCAAAAAAAAGTGAAGTTTTTAAGAAGACTTTTGATTTTAATATTAACAATTATTTTATTAATAAATATAACA
ACTATAGCAAAATATATTTT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MYCLKSIFKIGLTGGIGAGKSTISEMIKEKNIPVIDADKISREVLKLYPEILIRIKEVFGKEFLDDNGDLKRREFGSYIF
KNKNKRIEYENIIMPYIKKETFKRIKVLEENKESICVLDAPTLIEQGLYKYMDINILVWVDKDTQINRVVKRDGLNRSEV
TNRINSQMPMEEKKKFVDYMIDNSKDIENTKSELDKIFMEVMIKAKQKGGVL

Sequences:

>Translated_212_residues
MYCLKSIFKIGLTGGIGAGKSTISEMIKEKNIPVIDADKISREVLKLYPEILIRIKEVFGKEFLDDNGDLKRREFGSYIF
KNKNKRIEYENIIMPYIKKETFKRIKVLEENKESICVLDAPTLIEQGLYKYMDINILVWVDKDTQINRVVKRDGLNRSEV
TNRINSQMPMEEKKKFVDYMIDNSKDIENTKSELDKIFMEVMIKAKQKGGVL
>Mature_212_residues
MYCLKSIFKIGLTGGIGAGKSTISEMIKEKNIPVIDADKISREVLKLYPEILIRIKEVFGKEFLDDNGDLKRREFGSYIF
KNKNKRIEYENIIMPYIKKETFKRIKVLEENKESICVLDAPTLIEQGLYKYMDINILVWVDKDTQINRVVKRDGLNRSEV
TNRINSQMPMEEKKKFVDYMIDNSKDIENTKSELDKIFMEVMIKAKQKGGVL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=197, Percent_Identity=36.0406091370558, Blast_Score=128, Evalue=4e-30,
Organism=Homo sapiens, GI191252795, Length=197, Percent_Identity=36.0406091370558, Blast_Score=128, Evalue=4e-30,
Organism=Homo sapiens, GI110227607, Length=165, Percent_Identity=29.6969696969697, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI110227605, Length=166, Percent_Identity=30.7228915662651, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI110227603, Length=166, Percent_Identity=30.7228915662651, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI110227601, Length=166, Percent_Identity=30.7228915662651, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI205277394, Length=166, Percent_Identity=30.7228915662651, Blast_Score=81, Evalue=6e-16,
Organism=Escherichia coli, GI1786292, Length=200, Percent_Identity=29.5, Blast_Score=90, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17554944, Length=194, Percent_Identity=34.5360824742268, Blast_Score=134, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI25143409, Length=196, Percent_Identity=29.0816326530612, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320402, Length=194, Percent_Identity=31.4432989690722, Blast_Score=105, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24644728, Length=203, Percent_Identity=35.4679802955665, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24658602, Length=197, Percent_Identity=26.9035532994924, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 24745; Mature: 24745

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYCLKSIFKIGLTGGIGAGKSTISEMIKEKNIPVIDADKISREVLKLYPEILIRIKEVFG
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
KEFLDDNGDLKRREFGSYIFKNKNKRIEYENIIMPYIKKETFKRIKVLEENKESICVLDA
HHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
PTLIEQGLYKYMDINILVWVDKDTQINRVVKRDGLNRSEVTNRINSQMPMEEKKKFVDYM
HHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHH
IDNSKDIENTKSELDKIFMEVMIKAKQKGGVL
HCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MYCLKSIFKIGLTGGIGAGKSTISEMIKEKNIPVIDADKISREVLKLYPEILIRIKEVFG
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
KEFLDDNGDLKRREFGSYIFKNKNKRIEYENIIMPYIKKETFKRIKVLEENKESICVLDA
HHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
PTLIEQGLYKYMDINILVWVDKDTQINRVVKRDGLNRSEVTNRINSQMPMEEKKKFVDYM
HHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHH
IDNSKDIENTKSELDKIFMEVMIKAKQKGGVL
HCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]