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The map label for this gene is expZ [H]

Identifier: 226950275

GI number: 226950275

Start: 3258085

End: 3259563

Strand: Reverse

Name: expZ [H]

Synonym: CLM_3237

Alternate gene names: 226950275

Gene position: 3259563-3258085 (Counterclockwise)

Preceding gene: 226950276

Following gene: 226950274

Centisome position: 78.44

GC content: 31.58

Gene sequence:

>1479_bases
ATGTCTTTAATAAATGTTACAAACCTAACCTTTGCTTATGAAGGTAGCTATGATAATATTTTTGAAAATGTAAGTTTTCA
AATTGATACAGATTGGAAATTAGGGTTTACTGGAAGAAATGGAAGAGGAAAGACTACCTTTCTAAATCTTTTGCTTGGGA
AATACGAATATAATGGAAACATTTCAGCTGATGTGACTTTTGAATATTTTCCTTATGAGGTGCAGGAGCAGAGCAGTTTC
ACCATAGATATCATAAGGGAGATTAGTCCAAATTCAATGGATTGGGAAATAGTAAAAGAATTATCTTTGTTAGATATGGA
CTATGATGCTTTATATAGACAGTTTTATACACTATCTAAAGGAGAGCAGACTAAAGCACTGTTGGCTGCTATGTTTTTAA
AGGAGAGCTCCTTCTTGCTTATTGATGAGCCTACCAATCATTTGGATGCTGAAGCTAGGCAAAAACTAAGTAATTACTTG
AAAAAAAAGAAAGGATTTATTCTGATTTCACATGATAGGTCTTTTTTGGATAATTGTGTTGACCATATCTTGTCTATTAA
TAAAACTAATATTGAAATACAAAAAGGAAATTTTTCTTCATGGTGGAGAAACAAAGAATTACAAGATGGTTTTGAGCTAG
CAGAAAACGAAAAATTGAAAAAAGATATTAACAGACTTTCAAGCTCGGCAAAACGTACATCTACGTGGTCAGATAGTGTT
GAAGGCAGCAAGCATGGAACTACTAATTCTGGGAGCAAATTAGATAAAGGATATGTTGGACATAAAGCTGCAAAAATGAT
GAAGCGTGCTAAAAATATAGAAGCTAGACAACAAAACATGATTGAGGAAAAATCAAAGCTTCTTAAAAATATTGAATCTA
ATGAAAGTTTAAAAATAGTACCGCTTACTTTCCATGATAAAAAGCTTGTAGAACTTACAGATGTTGCAATTGAATATGAT
AATAGAATTGTCTGTGAAGGAGTAAGCTTCACTATAGAGCAAGGTGAAAGAATTGTTATTCAAGGAAAGAATGGCAGCGG
AAAATCAAGTATATTGAAATTAATTTATGGAGAAGACATCCCCCATAGTGGAATTGTAAGAAAGAATAATAAGTTAATCA
TTTCGTATGTTTCACAAGATACTTCAGATTTATATGGTAACTTATCTGAATATGCAGATAAACACTATATTGACGAGAGT
TTATTTAAATCGATACTTAGAAAGCTTGATTTTTCAAGAGAACAGTTTGAAAAGAATATCGAGGATTTTAGTGGAGGACA
GAAGAAAAAGGTATTGATTGCCAAAAGTTTGTGTGAACGGGCACATTTGTATATTTGGGATGAACCATTGAATTTTATTG
ATGTCATTTCTCGTATGCAGATTGAGAAATTGTTAATTGAACATGAACCTACAATTTTGTTTATTGAGCATGATAGTGCA
TTTTGTGAAAATGTTGCAACAAAAACAATAAAATTGTAA

Upstream 100 bases:

>100_bases
AGTCGGATATTGTAGGCGACACTTATATGGAGTAATAACAAGGTCGCCTATTGTTCCGACTTTGTTATTTATACTATTAA
ATACAGAGGAGGACAAAAAT

Downstream 100 bases:

>100_bases
AGGTAGAAATGAATATTAATATGTTTAATGGGAATATAAAAGTAACACACAATAGGCTCCATGCAAAGCCAGATGTTTTG
GGCGACGCTTGCATGGAGTA

Product: drug resistance ABC transporter RA2 family, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MSLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLNLLLGKYEYNGNISADVTFEYFPYEVQEQSSF
TIDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSKGEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYL
KKKKGFILISHDRSFLDNCVDHILSINKTNIEIQKGNFSSWWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSV
EGSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIVPLTFHDKKLVELTDVAIEYD
NRIVCEGVSFTIEQGERIVIQGKNGSGKSSILKLIYGEDIPHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHYIDES
LFKSILRKLDFSREQFEKNIEDFSGGQKKKVLIAKSLCERAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSA
FCENVATKTIKL

Sequences:

>Translated_492_residues
MSLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLNLLLGKYEYNGNISADVTFEYFPYEVQEQSSF
TIDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSKGEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYL
KKKKGFILISHDRSFLDNCVDHILSINKTNIEIQKGNFSSWWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSV
EGSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIVPLTFHDKKLVELTDVAIEYD
NRIVCEGVSFTIEQGERIVIQGKNGSGKSSILKLIYGEDIPHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHYIDES
LFKSILRKLDFSREQFEKNIEDFSGGQKKKVLIAKSLCERAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSA
FCENVATKTIKL
>Mature_491_residues
SLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLNLLLGKYEYNGNISADVTFEYFPYEVQEQSSFT
IDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSKGEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYLK
KKKGFILISHDRSFLDNCVDHILSINKTNIEIQKGNFSSWWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSVE
GSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIVPLTFHDKKLVELTDVAIEYDN
RIVCEGVSFTIEQGERIVIQGKNGSGKSSILKLIYGEDIPHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHYIDESL
FKSILRKLDFSREQFEKNIEDFSGGQKKKVLIAKSLCERAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSAF
CENVATKTIKL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI10947137, Length=526, Percent_Identity=23.7642585551331, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI27881506, Length=526, Percent_Identity=23.7642585551331, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI148612853, Length=537, Percent_Identity=23.8361266294227, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI10947135, Length=400, Percent_Identity=25.25, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI69354671, Length=400, Percent_Identity=25.25, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI157502201, Length=196, Percent_Identity=29.5918367346939, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI157502203, Length=190, Percent_Identity=30, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI90421313, Length=184, Percent_Identity=25.5434782608696, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367384, Length=529, Percent_Identity=25.5198487712665, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1787041, Length=528, Percent_Identity=25.3787878787879, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1789751, Length=505, Percent_Identity=25.7425742574257, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1787182, Length=549, Percent_Identity=23.4972677595628, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788165, Length=191, Percent_Identity=27.2251308900524, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787164, Length=192, Percent_Identity=26.0416666666667, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789962, Length=197, Percent_Identity=25.8883248730964, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87081709, Length=198, Percent_Identity=25.7575757575758, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=519, Percent_Identity=22.3506743737958, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17555318, Length=380, Percent_Identity=25.7894736842105, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17553372, Length=508, Percent_Identity=23.8188976377953, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320874, Length=530, Percent_Identity=20.7547169811321, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6321121, Length=385, Percent_Identity=24.1558441558442, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6325030, Length=186, Percent_Identity=27.4193548387097, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323278, Length=198, Percent_Identity=28.7878787878788, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641342, Length=529, Percent_Identity=25.7088846880907, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24642252, Length=536, Percent_Identity=23.5074626865672, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI18859989, Length=536, Percent_Identity=23.5074626865672, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24666836, Length=519, Percent_Identity=22.7360308285164, Blast_Score=108, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 56554; Mature: 56423

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLNLLLGKYEYNGN
CCEEEEEEEEEEEECCHHHHHCCCEEEEECCEEEEECCCCCCCHHHHHHHHHHHEEECCC
ISADVTFEYFPYEVQEQSSFTIDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSK
CEEEEEEEECCCEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
GEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYLKKKKGFILISHDRSFLDNCV
CCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHH
DHILSINKTNIEIQKGNFSSWWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSV
HHHHCCCCCEEEEECCCCHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
EGSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
PLTFHDKKLVELTDVAIEYDNRIVCEGVSFTIEQGERIVIQGKNGSGKSSILKLIYGEDI
EEEECCCHHHHHHHEEEECCCEEEEECCEEEEECCCEEEEECCCCCCHHHHHHHEECCCC
PHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHYIDESLFKSILRKLDFSREQFEKNI
CCCCEEECCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EDFSGGQKKKVLIAKSLCERAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSA
HHHCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHH
FCENVATKTIKL
HHHHHHHHHCCC
>Mature Secondary Structure 
SLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLNLLLGKYEYNGN
CEEEEEEEEEEEECCHHHHHCCCEEEEECCEEEEECCCCCCCHHHHHHHHHHHEEECCC
ISADVTFEYFPYEVQEQSSFTIDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSK
CEEEEEEEECCCEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
GEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYLKKKKGFILISHDRSFLDNCV
CCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHH
DHILSINKTNIEIQKGNFSSWWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSV
HHHHCCCCCEEEEECCCCHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
EGSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
PLTFHDKKLVELTDVAIEYDNRIVCEGVSFTIEQGERIVIQGKNGSGKSSILKLIYGEDI
EEEECCCHHHHHHHEEEECCCEEEEECCEEEEECCCEEEEECCCCCCHHHHHHHEECCCC
PHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHYIDESLFKSILRKLDFSREQFEKNI
CCCCEEECCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EDFSGGQKKKVLIAKSLCERAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSA
HHHCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHH
FCENVATKTIKL
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]