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The map label for this gene is glsA [H]

Identifier: 226950219

GI number: 226950219

Start: 3185530

End: 3186447

Strand: Reverse

Name: glsA [H]

Synonym: CLM_3173

Alternate gene names: 226950219

Gene position: 3186447-3185530 (Counterclockwise)

Preceding gene: 226950220

Following gene: 226950216

Centisome position: 76.68

GC content: 32.9

Gene sequence:

>918_bases
ATGAACAGACTGCTTAAGACGATTATAGAAAATAATAGAAAATGGATAAGTGAAGGAAAGGTGGCCTCATATATTCCTGA
ACTTTCTAAAATGGATAAAAATTTACTAGGTATTTCTGTATGTACCCTAGGAGGAGAAGAATATTGGGAAGGCGATGCTG
AAGTTAAGTTTACTATTCAAAGTATATCAAAAATAGTAACTTTAATGCTAGCCATAATAGACAATGGAGAGGATTATGTT
TTTTCAAAGGTAGGAATGGAACCTACAGAAACTGCTTTTAATTCTATAGTAAATTTAGAAGCAAAAGAATCTCATAAGCC
TATAAATCCAATGATAAATGCTGGTGCCATAGTGGTGGCTTCTATGGTAGCTGGAAAAGATTCAGATGAAAAGTTTGATA
GAATCTTAAAGTTTACTAGAAAAATAAGTGGTAATAATAATATTGATATAAATCTAAATGTATATAAATCCGAAAAAGAA
ACAGGACATAGAAACAGAGCTCTTGCTTATTTTATGAAAAGCACAGGAGCCCTCAAGGGAAATGTAGAAGAGATTTTAGA
TGTGTATTTTAAACAATGTTCTATAGAAATTACTTGTAAAGATTTAGCTAGAATAGGAGTTATGTTAGCTAATGATGGGG
TATCTCCTTATACTGGTGATAGAATAGTTCCAAGGCATGTGGCTAGAATTGTAAAAACTATAATGGTAACCTGTGGTATG
TATGATGCTTCAGGAAATTTTGCAGTACATATCGGAATACCTGCTAAAAGTGGAGTTGGAGGAGGTATAGTTGCCTGTGC
TCCGAGAAGAATGGGTATAGGGGTTTTAGGCACAGCTTTAGATGAAAAGGGTAATAGTATAGCTGGAACTAAGATATTAG
AAGAGCTTTCAAAGCAATTAGATTTAAGTATTTTTTAA

Upstream 100 bases:

>100_bases
AAAAATATACAATTTTTATATAATAGAAATTAACTTAAAAAAATTATATAAAAGATGTATAATTATAGTATAATATTATA
AAGATTATGGAGAAACATAT

Downstream 100 bases:

>100_bases
AAGATAAAAATATGATAAAATATCTTCTTTAATTGCTCAGTTTAATAATAAAGCCTCAGCAAATTGTTATAAAGATAAAA
CCATAAAAGAATTTATCATT

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNRLLKTIIENNRKWISEGKVASYIPELSKMDKNLLGISVCTLGGEEYWEGDAEVKFTIQSISKIVTLMLAIIDNGEDYV
FSKVGMEPTETAFNSIVNLEAKESHKPINPMINAGAIVVASMVAGKDSDEKFDRILKFTRKISGNNNIDINLNVYKSEKE
TGHRNRALAYFMKSTGALKGNVEEILDVYFKQCSIEITCKDLARIGVMLANDGVSPYTGDRIVPRHVARIVKTIMVTCGM
YDASGNFAVHIGIPAKSGVGGGIVACAPRRMGIGVLGTALDEKGNSIAGTKILEELSKQLDLSIF

Sequences:

>Translated_305_residues
MNRLLKTIIENNRKWISEGKVASYIPELSKMDKNLLGISVCTLGGEEYWEGDAEVKFTIQSISKIVTLMLAIIDNGEDYV
FSKVGMEPTETAFNSIVNLEAKESHKPINPMINAGAIVVASMVAGKDSDEKFDRILKFTRKISGNNNIDINLNVYKSEKE
TGHRNRALAYFMKSTGALKGNVEEILDVYFKQCSIEITCKDLARIGVMLANDGVSPYTGDRIVPRHVARIVKTIMVTCGM
YDASGNFAVHIGIPAKSGVGGGIVACAPRRMGIGVLGTALDEKGNSIAGTKILEELSKQLDLSIF
>Mature_305_residues
MNRLLKTIIENNRKWISEGKVASYIPELSKMDKNLLGISVCTLGGEEYWEGDAEVKFTIQSISKIVTLMLAIIDNGEDYV
FSKVGMEPTETAFNSIVNLEAKESHKPINPMINAGAIVVASMVAGKDSDEKFDRILKFTRKISGNNNIDINLNVYKSEKE
TGHRNRALAYFMKSTGALKGNVEEILDVYFKQCSIEITCKDLARIGVMLANDGVSPYTGDRIVPRHVARIVKTIMVTCGM
YDASGNFAVHIGIPAKSGVGGGIVACAPRRMGIGVLGTALDEKGNSIAGTKILEELSKQLDLSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=283, Percent_Identity=41.696113074205, Blast_Score=234, Evalue=5e-62,
Organism=Homo sapiens, GI20336214, Length=286, Percent_Identity=39.8601398601399, Blast_Score=221, Evalue=5e-58,
Organism=Escherichia coli, GI1787804, Length=304, Percent_Identity=42.7631578947368, Blast_Score=254, Evalue=5e-69,
Organism=Escherichia coli, GI1786693, Length=306, Percent_Identity=35.6209150326797, Blast_Score=207, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17532727, Length=290, Percent_Identity=41.3793103448276, Blast_Score=228, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17507019, Length=289, Percent_Identity=40.8304498269896, Blast_Score=223, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI193204073, Length=311, Percent_Identity=36.0128617363344, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI193204075, Length=314, Percent_Identity=36.624203821656, Blast_Score=207, Evalue=5e-54,
Organism=Drosophila melanogaster, GI281363241, Length=295, Percent_Identity=38.9830508474576, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI281363239, Length=295, Percent_Identity=38.9830508474576, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24653162, Length=295, Percent_Identity=38.9830508474576, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24653164, Length=295, Percent_Identity=38.9830508474576, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24653158, Length=295, Percent_Identity=38.9830508474576, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24653156, Length=295, Percent_Identity=38.9830508474576, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24653166, Length=295, Percent_Identity=38.9830508474576, Blast_Score=214, Evalue=5e-56,
Organism=Drosophila melanogaster, GI116008307, Length=295, Percent_Identity=38.9830508474576, Blast_Score=214, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 33271; Mature: 33271

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLLKTIIENNRKWISEGKVASYIPELSKMDKNLLGISVCTLGGEEYWEGDAEVKFTIQ
CHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCHHHEEEEEECCCHHHCCCCCEEEEEHH
SISKIVTLMLAIIDNGEDYVFSKVGMEPTETAFNSIVNLEAKESHKPINPMINAGAIVVA
HHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHH
SMVAGKDSDEKFDRILKFTRKISGNNNIDINLNVYKSEKETGHRNRALAYFMKSTGALKG
HHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCC
NVEEILDVYFKQCSIEITCKDLARIGVMLANDGVSPYTGDRIVPRHVARIVKTIMVTCGM
CHHHHHHHHHHHCCEEEEHHHHHHHCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
YDASGNFAVHIGIPAKSGVGGGIVACAPRRMGIGVLGTALDEKGNSIAGTKILEELSKQL
EECCCCEEEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHC
DLSIF
CCCCC
>Mature Secondary Structure
MNRLLKTIIENNRKWISEGKVASYIPELSKMDKNLLGISVCTLGGEEYWEGDAEVKFTIQ
CHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCHHHEEEEEECCCHHHCCCCCEEEEEHH
SISKIVTLMLAIIDNGEDYVFSKVGMEPTETAFNSIVNLEAKESHKPINPMINAGAIVVA
HHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHH
SMVAGKDSDEKFDRILKFTRKISGNNNIDINLNVYKSEKETGHRNRALAYFMKSTGALKG
HHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCC
NVEEILDVYFKQCSIEITCKDLARIGVMLANDGVSPYTGDRIVPRHVARIVKTIMVTCGM
CHHHHHHHHHHHCCEEEEHHHHHHHCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
YDASGNFAVHIGIPAKSGVGGGIVACAPRRMGIGVLGTALDEKGNSIAGTKILEELSKQL
EECCCCEEEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHC
DLSIF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA