| Definition | Clostridium botulinum A2 str. Kyoto chromosome, complete genome. |
|---|---|
| Accession | NC_012563 |
| Length | 4,155,278 |
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The map label for this gene is hopD2 [H]
Identifier: 226949484
GI number: 226949484
Start: 2500654
End: 2503116
Strand: Direct
Name: hopD2 [H]
Synonym: CLM_2419
Alternate gene names: 226949484
Gene position: 2500654-2503116 (Clockwise)
Preceding gene: 226949483
Following gene: 226949489
Centisome position: 60.18
GC content: 28.62
Gene sequence:
>2463_bases TTGAAAAAAAATTTTAAATTAAATATATTTATTCTATTAATATTAGTAGGTGTATTTTCCTTTTTCTCAATAACAAATAA AGCTACTATAGCTACAGATGATAATAATGGTGTACATCTAGTTTTAGATTCACGAAATAACAATAAGGTTCCAAAAAAAT TTCGTAAATCCTCTGATATATCAAATGTAGAAAAAGATAAAAATGTGAATCTTACTGGATTAAACACATTAAATATTTCT GGTAGTAAGCAATTTTCTAAGCAAAATCTTCCCCTTATAATAAATAATATAGGAACTTCACTACCTATAACAGTTGTTGA TTTAAGGCAGGAATCCCATGGGTTTATTAATGGATTACCTGTTAGTTGGGCTAATAAAAAAAATAATGCTAATGCAGGTT TAACAAAAACTGAAGTTTTAAAAGATGAAAATAATAAATTAAAAAGTATTAAATTGAATTCACCTATTAGTTTTTACAAT CATCCTGATAAAACTATAATTCCAACAAAAGTTGAAAATGAAGAACAGCTTGTTAAGCATAATTCATTATCATATGTCCG CGTACCTGTTACCGATACAAAGTTACCTACAGATGATATGGTTGATTATTTTGTTGATGTGATTAAATCCAACCCTAAGG ATACATGGTACCATTTTCACTGTAAGCAAGGTATAGGAAGAACTACTACTTTTATGATTATGTATGATATGATGAGAAAT GCAAAAGAAGTTCCTGCTGATGACATTATAAAAAGACAATTATTATTAGCAAACTTTGATGAAAAGCATATGAAATCTTT TTATAATAACGAAAGACATGATTTCTTACAAAATTTCTATAAATATGCTAAGGAAAATGGTAGTAATTTCGATGTAAAAT GGAGCGATTGGAAGAAAACTCTTAACACTAAAAGCAATAGTTTTTTTCCTATTGCTTCTTCAAATAAAGAATCTTCTAAT TATATAAAAAACCCTAAAATTCCAACCCATCTATATGTTATTTCTCAAAATAAAATGACTTCTAGCGAAAGAACAATGAT AGCTACTCTTCAAGGGATAGTTAATAATCATTGTTCTCATCAAATATATACCCTTAATTCTTCACAACCAGATTACCAAA CATGGCTAAATGATTTAAAAAATAATTATGGTGTATCTTACAATATTGTTTCAGACCCCTGGGAGTTATTAAATATATAT AAAGACTATGTTAAAGGCTATGTACTTTATAGCAACAAATCATCAAAAGATCCTTCTATAAATAATGCTTGTTCCCTTGC TTCATTAAAAAATTCCATTGCAATTGATGAAATCATTGAAAATAAAGTACGAGCCCACAGCATAACAAATATTAGTGGAG ATTGTAGAAATACAGATAAAGATTGGGCCTATAATAATTTGTGGAATTCTGGATTAAATCATTCAATAGTAATTCAATTA TCTCCTAAAAAAGAAACAGCTTTAAGAGACTACGCTATAATGACTAAGTCTCTAATATTTTATGAAGATAGCATAAATGA TACATCCCTTAGAGATAAAGTATTCTCCTCTATGGATCCTAATTCTATTTGTTTAGGTTGGGGACCAGATGAATTTATAA ATGTAAGCACTTCATCAAAACATGGTGTAAGTATGATAGCCGCAGATTGGTCTTATAATTTAACTGTATTGAGCGCCTTT CCCTCATCCCCTATGGCTCAAAAATCCTCATCAAATATAACTAATAAAAAAAATGTTCATTATGTAACATTTATTATGTC AGATGGAGATAACCAGCAATGGAATCTTGGAACTAATTATGGTTCTCCTAAGTGGTATGGTTCTCCTTATAGGGGTAACT TTAATCTTGGTTGGTCTTTAAGCCCATCTTTATATTATTTAGCTCCTACTGTTTTTAATTTATATTATAAAAGCGCCTCT CATGGATCTACTAATGATTATTTTATAGTATCACCCTCAGGCAATGGGTATATGTATCCTAGCAAATATGATAAGAATGC CCTAGGCGCATATATTAATACATTAGATGACTATATGAAAAAAGTAGATGAAAAATATGTAGCAATTATAGATGACTCTT CTTTTTATAATAATAAACTTTGGGATAATTTTACTGCCAAGCCTAATATACAAGGATTGTTTTATCTTGATTACCGAAAG CATAACAACTATCATGGAGAAATTATTTGGTCTAATAATAAACCCATAGTATCTTGTAGGGACCTACTTTGGAATAATCT AGAAAGCGAAGATGAATTGGTTAAAAATATTAATAAAAGAATTAACTCTGGTGAGACAGACATTCATAATCCTAATAGCT ACACCTTTGTATATGTTCATGTTTGGAGCAAAAACTTAAATAATATTGAAGATACTGTTAATAAGCTCAAGAAAAATCCT AAAGTAGAAATAGTAACTCCTGAAATATTTATGGAATTGATAAATAAAAATGTTAAACATTGA
Upstream 100 bases:
>100_bases GTATACAAGTTATATAAATAACACATTCTATATTTATATTAAGTAATTGTTAATTAAAGATACAATTTACTTAAAATTAA TATAAAAGAGGTGATTTGGA
Downstream 100 bases:
>100_bases TTCTCAAAAATATTTAACCTACTATAAACAAATTTTAGTAGGTTAAATATGTGATCTAAAAATAATTAATTTATAAAAGT GATTTATCTGGAGTTACAAT
Product: hypothetical protein
Products: NA
Alternate protein names: Tyrosine-protein phosphatase hopPtoD2 [H]
Number of amino acids: Translated: 820; Mature: 820
Protein sequence:
>820_residues MKKNFKLNIFILLILVGVFSFFSITNKATIATDDNNGVHLVLDSRNNNKVPKKFRKSSDISNVEKDKNVNLTGLNTLNIS GSKQFSKQNLPLIINNIGTSLPITVVDLRQESHGFINGLPVSWANKKNNANAGLTKTEVLKDENNKLKSIKLNSPISFYN HPDKTIIPTKVENEEQLVKHNSLSYVRVPVTDTKLPTDDMVDYFVDVIKSNPKDTWYHFHCKQGIGRTTTFMIMYDMMRN AKEVPADDIIKRQLLLANFDEKHMKSFYNNERHDFLQNFYKYAKENGSNFDVKWSDWKKTLNTKSNSFFPIASSNKESSN YIKNPKIPTHLYVISQNKMTSSERTMIATLQGIVNNHCSHQIYTLNSSQPDYQTWLNDLKNNYGVSYNIVSDPWELLNIY KDYVKGYVLYSNKSSKDPSINNACSLASLKNSIAIDEIIENKVRAHSITNISGDCRNTDKDWAYNNLWNSGLNHSIVIQL SPKKETALRDYAIMTKSLIFYEDSINDTSLRDKVFSSMDPNSICLGWGPDEFINVSTSSKHGVSMIAADWSYNLTVLSAF PSSPMAQKSSSNITNKKNVHYVTFIMSDGDNQQWNLGTNYGSPKWYGSPYRGNFNLGWSLSPSLYYLAPTVFNLYYKSAS HGSTNDYFIVSPSGNGYMYPSKYDKNALGAYINTLDDYMKKVDEKYVAIIDDSSFYNNKLWDNFTAKPNIQGLFYLDYRK HNNYHGEIIWSNNKPIVSCRDLLWNNLESEDELVKNINKRINSGETDIHNPNSYTFVYVHVWSKNLNNIEDTVNKLKKNP KVEIVTPEIFMELINKNVKH
Sequences:
>Translated_820_residues MKKNFKLNIFILLILVGVFSFFSITNKATIATDDNNGVHLVLDSRNNNKVPKKFRKSSDISNVEKDKNVNLTGLNTLNIS GSKQFSKQNLPLIINNIGTSLPITVVDLRQESHGFINGLPVSWANKKNNANAGLTKTEVLKDENNKLKSIKLNSPISFYN HPDKTIIPTKVENEEQLVKHNSLSYVRVPVTDTKLPTDDMVDYFVDVIKSNPKDTWYHFHCKQGIGRTTTFMIMYDMMRN AKEVPADDIIKRQLLLANFDEKHMKSFYNNERHDFLQNFYKYAKENGSNFDVKWSDWKKTLNTKSNSFFPIASSNKESSN YIKNPKIPTHLYVISQNKMTSSERTMIATLQGIVNNHCSHQIYTLNSSQPDYQTWLNDLKNNYGVSYNIVSDPWELLNIY KDYVKGYVLYSNKSSKDPSINNACSLASLKNSIAIDEIIENKVRAHSITNISGDCRNTDKDWAYNNLWNSGLNHSIVIQL SPKKETALRDYAIMTKSLIFYEDSINDTSLRDKVFSSMDPNSICLGWGPDEFINVSTSSKHGVSMIAADWSYNLTVLSAF PSSPMAQKSSSNITNKKNVHYVTFIMSDGDNQQWNLGTNYGSPKWYGSPYRGNFNLGWSLSPSLYYLAPTVFNLYYKSAS HGSTNDYFIVSPSGNGYMYPSKYDKNALGAYINTLDDYMKKVDEKYVAIIDDSSFYNNKLWDNFTAKPNIQGLFYLDYRK HNNYHGEIIWSNNKPIVSCRDLLWNNLESEDELVKNINKRINSGETDIHNPNSYTFVYVHVWSKNLNNIEDTVNKLKKNP KVEIVTPEIFMELINKNVKH >Mature_820_residues MKKNFKLNIFILLILVGVFSFFSITNKATIATDDNNGVHLVLDSRNNNKVPKKFRKSSDISNVEKDKNVNLTGLNTLNIS GSKQFSKQNLPLIINNIGTSLPITVVDLRQESHGFINGLPVSWANKKNNANAGLTKTEVLKDENNKLKSIKLNSPISFYN HPDKTIIPTKVENEEQLVKHNSLSYVRVPVTDTKLPTDDMVDYFVDVIKSNPKDTWYHFHCKQGIGRTTTFMIMYDMMRN AKEVPADDIIKRQLLLANFDEKHMKSFYNNERHDFLQNFYKYAKENGSNFDVKWSDWKKTLNTKSNSFFPIASSNKESSN YIKNPKIPTHLYVISQNKMTSSERTMIATLQGIVNNHCSHQIYTLNSSQPDYQTWLNDLKNNYGVSYNIVSDPWELLNIY KDYVKGYVLYSNKSSKDPSINNACSLASLKNSIAIDEIIENKVRAHSITNISGDCRNTDKDWAYNNLWNSGLNHSIVIQL SPKKETALRDYAIMTKSLIFYEDSINDTSLRDKVFSSMDPNSICLGWGPDEFINVSTSSKHGVSMIAADWSYNLTVLSAF PSSPMAQKSSSNITNKKNVHYVTFIMSDGDNQQWNLGTNYGSPKWYGSPYRGNFNLGWSLSPSLYYLAPTVFNLYYKSAS HGSTNDYFIVSPSGNGYMYPSKYDKNALGAYINTLDDYMKKVDEKYVAIIDDSSFYNNKLWDNFTAKPNIQGLFYLDYRK HNNYHGEIIWSNNKPIVSCRDLLWNNLESEDELVKNINKRINSGETDIHNPNSYTFVYVHVWSKNLNNIEDTVNKLKKNP KVEIVTPEIFMELINKNVKH
Specific function: Effector showing tyrosine-phosphatase activity required for host defense suppression. Functions inside plant cells causing suppression of HR (hypersensitive response), PR1 gene expression and oxidative burst probably by interfering with a MAPK (mitogen- a
COG id: NA
COG function: NA
Gene ontology:
Cell location: Secreted. Note=Secreted via type III secretion system (TTSS) [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 tyrosine-protein phosphatase domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000387 - InterPro: IPR016130 - InterPro: IPR000242 [H]
Pfam domain/function: PF00102 Y_phosphatase [H]
EC number: =3.1.3.48 [H]
Molecular weight: Translated: 93927; Mature: 93927
Theoretical pI: Translated: 9.17; Mature: 9.17
Prosite motif: PS00383 TYR_PHOSPHATASE_1 ; PS50056 TYR_PHOSPHATASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKNFKLNIFILLILVGVFSFFSITNKATIATDDNNGVHLVLDSRNNNKVPKKFRKSSDI CCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCHHHHHCCCC SNVEKDKNVNLTGLNTLNISGSKQFSKQNLPLIINNIGTSLPITVVDLRQESHGFINGLP CCCCCCCCCEEEEEEEEECCCCCHHCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCC VSWANKKNNANAGLTKTEVLKDENNKLKSIKLNSPISFYNHPDKTIIPTKVENEEQLVKH CEECCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCEEECCCCCCEECCCCCCCHHHHHHC NSLSYVRVPVTDTKLPTDDMVDYFVDVIKSNPKDTWYHFHCKQGIGRTTTFMIMYDMMRN CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHC AKEVPADDIIKRQLLLANFDEKHMKSFYNNERHDFLQNFYKYAKENGSNFDVKWSDWKKT HHCCCHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEHHHHHH LNTKSNSFFPIASSNKESSNYIKNPKIPTHLYVISQNKMTSSERTMIATLQGIVNNHCSH HCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCC QIYTLNSSQPDYQTWLNDLKNNYGVSYNIVSDPWELLNIYKDYVKGYVLYSNKSSKDPSI EEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCEEEEECCCCCCCCCC NNACSLASLKNSIAIDEIIENKVRAHSITNISGDCRNTDKDWAYNNLWNSGLNHSIVIQL CCHHHHHHHHCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEE SPKKETALRDYAIMTKSLIFYEDSINDTSLRDKVFSSMDPNSICLGWGPDEFINVSTSSK CCCCHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCCCCCEEEECCCCCEEEECCCCC HGVSMIAADWSYNLTVLSAFPSSPMAQKSSSNITNKKNVHYVTFIMSDGDNQQWNLGTNY CCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCC GSPKWYGSPYRGNFNLGWSLSPSLYYLAPTVFNLYYKSASHGSTNDYFIVSPSGNGYMYP CCCCCCCCCCCCCEEECEEECCCEEEHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEECC SKYDKNALGAYINTLDDYMKKVDEKYVAIIDDSSFYNNKLWDNFTAKPNIQGLFYLDYRK CCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEC HNNYHGEIIWSNNKPIVSCRDLLWNNLESEDELVKNINKRINSGETDIHNPNSYTFVYVH CCCCEEEEEECCCCCEEHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEE VWSKNLNNIEDTVNKLKKNPKVEIVTPEIFMELINKNVKH EECCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHCCCC >Mature Secondary Structure MKKNFKLNIFILLILVGVFSFFSITNKATIATDDNNGVHLVLDSRNNNKVPKKFRKSSDI CCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCHHHHHCCCC SNVEKDKNVNLTGLNTLNISGSKQFSKQNLPLIINNIGTSLPITVVDLRQESHGFINGLP CCCCCCCCCEEEEEEEEECCCCCHHCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCC VSWANKKNNANAGLTKTEVLKDENNKLKSIKLNSPISFYNHPDKTIIPTKVENEEQLVKH CEECCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCEEECCCCCCEECCCCCCCHHHHHHC NSLSYVRVPVTDTKLPTDDMVDYFVDVIKSNPKDTWYHFHCKQGIGRTTTFMIMYDMMRN CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHC AKEVPADDIIKRQLLLANFDEKHMKSFYNNERHDFLQNFYKYAKENGSNFDVKWSDWKKT HHCCCHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEHHHHHH LNTKSNSFFPIASSNKESSNYIKNPKIPTHLYVISQNKMTSSERTMIATLQGIVNNHCSH HCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCC QIYTLNSSQPDYQTWLNDLKNNYGVSYNIVSDPWELLNIYKDYVKGYVLYSNKSSKDPSI EEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCEEEEECCCCCCCCCC NNACSLASLKNSIAIDEIIENKVRAHSITNISGDCRNTDKDWAYNNLWNSGLNHSIVIQL CCHHHHHHHHCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEE SPKKETALRDYAIMTKSLIFYEDSINDTSLRDKVFSSMDPNSICLGWGPDEFINVSTSSK CCCCHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCCCCCEEEECCCCCEEEECCCCC HGVSMIAADWSYNLTVLSAFPSSPMAQKSSSNITNKKNVHYVTFIMSDGDNQQWNLGTNY CCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCC GSPKWYGSPYRGNFNLGWSLSPSLYYLAPTVFNLYYKSASHGSTNDYFIVSPSGNGYMYP CCCCCCCCCCCCCEEECEEECCCEEEHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEECC SKYDKNALGAYINTLDDYMKKVDEKYVAIIDDSSFYNNKLWDNFTAKPNIQGLFYLDYRK CCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEC HNNYHGEIIWSNNKPIVSCRDLLWNNLESEDELVKNINKRINSGETDIHNPNSYTFVYVH CCCCEEEEEECCCCCEEHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEE VWSKNLNNIEDTVNKLKKNPKVEIVTPEIFMELINKNVKH EECCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12437299; 12828636; 12928499 [H]