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The map label for this gene is yxdK [H]

Identifier: 226949418

GI number: 226949418

Start: 2420214

End: 2421233

Strand: Reverse

Name: yxdK [H]

Synonym: CLM_2346

Alternate gene names: 226949418

Gene position: 2421233-2420214 (Counterclockwise)

Preceding gene: 226949419

Following gene: 226949417

Centisome position: 58.27

GC content: 25.88

Gene sequence:

>1020_bases
ATGAGTATAGGTGAATTTATTAAGGATAAAATTCTTATAATATCATGTAATATGCTGATTTTTATTTTATTATCAATTAT
AATACTTGCTAGTAATGTTGATTTAATTATAATTTTATTTATATTTTGTATATGGTTCTTTCCATTAGTTTCATATATGA
TTTTGGAATTTATAAAATATAAAAATTATTATGATGAAATTGATAGCATATTAGAAAAATTGGACAAGAAATATCTGCTT
CCAGAGCTACTAAAGGAAGCAAACTTTATTCAAGGGGAAAAGCTTAATTCTATACTTAAAGAGATAAGCAGGGATATGCA
CGAAAATGTAAAGTACTATAAGGATATGCAAGAAGATTATAGAGAATACATAGAGGCATGGGTTCATGAAATTAAAACAC
CAATAGCTTCTACAAAATTAATAATTGAAAATAATCGAAATGAAGTAACCAATAAAATAGACTTTCAGATAGATAGAATT
GAGGGGTTTGTAGAACAGGTGCTTTATTATTCTCGAAGCAACAATGTTAGTAAAGATTATATCATAAAACAAATTAACCT
TGATTATGTAGTAAAGAATGTAATTAAAAGAAATTATAGAGATTTTATTCATAAGAAAATAAAATTAGATATAAAAGACA
TTGATGAAATTGTGCATAGTGATGGAAAATGGGTTGAATTCATTATTAATCAGATAATAGTAAATTCTATAAAGTACTCA
AATAGCAAAGAGCCAATGATAAGTATATATTCAACTAAAAAAGCTAATTCAGTAATGTTAACCATAGAAGATAATGGAGC
TGGCATAATAGATAAAGATATAAATAGAGTCTTAGAAAAAGGATTTACCGGTGAGAATGGAAGAAAATTTAGCAAAGGTA
CAGGAATGGGCTTATATCTATGTGAAAAGCTTTGTTCAAAATTAGGGCTAAGAATTAGTATTGACTCTGAGGTAAATAGG
GGAACTAAAGTTACATTAATATTTCCTCTATCAAGTATGATAACTTTTACAGATTATTAA

Upstream 100 bases:

>100_bases
GCACCTTAACTGTTAATATTAATAGATTAAGAAAGAAGCTTCAAGAGATAGGGATAGAAAATCCAATAGAAACAAGGAGA
GGGTTAGGGTATATAATGCC

Downstream 100 bases:

>100_bases
GGTTTAACTGTTCAACCATATTTTATAATATATTGTATTGAATGTATTTTTTTTATTAATATTAATTTAAAATTTAATTT
AATAAGTTAAAAATTTAAAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSIGEFIKDKILIISCNMLIFILLSIIILASNVDLIIILFIFCIWFFPLVSYMILEFIKYKNYYDEIDSILEKLDKKYLL
PELLKEANFIQGEKLNSILKEISRDMHENVKYYKDMQEDYREYIEAWVHEIKTPIASTKLIIENNRNEVTNKIDFQIDRI
EGFVEQVLYYSRSNNVSKDYIIKQINLDYVVKNVIKRNYRDFIHKKIKLDIKDIDEIVHSDGKWVEFIINQIIVNSIKYS
NSKEPMISIYSTKKANSVMLTIEDNGAGIIDKDINRVLEKGFTGENGRKFSKGTGMGLYLCEKLCSKLGLRISIDSEVNR
GTKVTLIFPLSSMITFTDY

Sequences:

>Translated_339_residues
MSIGEFIKDKILIISCNMLIFILLSIIILASNVDLIIILFIFCIWFFPLVSYMILEFIKYKNYYDEIDSILEKLDKKYLL
PELLKEANFIQGEKLNSILKEISRDMHENVKYYKDMQEDYREYIEAWVHEIKTPIASTKLIIENNRNEVTNKIDFQIDRI
EGFVEQVLYYSRSNNVSKDYIIKQINLDYVVKNVIKRNYRDFIHKKIKLDIKDIDEIVHSDGKWVEFIINQIIVNSIKYS
NSKEPMISIYSTKKANSVMLTIEDNGAGIIDKDINRVLEKGFTGENGRKFSKGTGMGLYLCEKLCSKLGLRISIDSEVNR
GTKVTLIFPLSSMITFTDY
>Mature_338_residues
SIGEFIKDKILIISCNMLIFILLSIIILASNVDLIIILFIFCIWFFPLVSYMILEFIKYKNYYDEIDSILEKLDKKYLLP
ELLKEANFIQGEKLNSILKEISRDMHENVKYYKDMQEDYREYIEAWVHEIKTPIASTKLIIENNRNEVTNKIDFQIDRIE
GFVEQVLYYSRSNNVSKDYIIKQINLDYVVKNVIKRNYRDFIHKKIKLDIKDIDEIVHSDGKWVEFIINQIIVNSIKYSN
SKEPMISIYSTKKANSVMLTIEDNGAGIIDKDINRVLEKGFTGENGRKFSKGTGMGLYLCEKLCSKLGLRISIDSEVNRG
TKVTLIFPLSSMITFTDY

Specific function: Probable member of the two-component regulatory system yxdK/yxdJ. May activate yxdJ in response to the antibacterial protein LL-37 [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39658; Mature: 39527

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIGEFIKDKILIISCNMLIFILLSIIILASNVDLIIILFIFCIWFFPLVSYMILEFIKY
CCHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNYYDEIDSILEKLDKKYLLPELLKEANFIQGEKLNSILKEISRDMHENVKYYKDMQEDY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REYIEAWVHEIKTPIASTKLIIENNRNEVTNKIDFQIDRIEGFVEQVLYYSRSNNVSKDY
HHHHHHHHHHHHCCHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IIKQINLDYVVKNVIKRNYRDFIHKKIKLDIKDIDEIVHSDGKWVEFIINQIIVNSIKYS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
NSKEPMISIYSTKKANSVMLTIEDNGAGIIDKDINRVLEKGFTGENGRKFSKGTGMGLYL
CCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
CEKLCSKLGLRISIDSEVNRGTKVTLIFPLSSMITFTDY
HHHHHHHCCCEEEECCCCCCCCEEEEEEEHHHHHHCCCC
>Mature Secondary Structure 
SIGEFIKDKILIISCNMLIFILLSIIILASNVDLIIILFIFCIWFFPLVSYMILEFIKY
CHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNYYDEIDSILEKLDKKYLLPELLKEANFIQGEKLNSILKEISRDMHENVKYYKDMQEDY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REYIEAWVHEIKTPIASTKLIIENNRNEVTNKIDFQIDRIEGFVEQVLYYSRSNNVSKDY
HHHHHHHHHHHHCCHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IIKQINLDYVVKNVIKRNYRDFIHKKIKLDIKDIDEIVHSDGKWVEFIINQIIVNSIKYS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
NSKEPMISIYSTKKANSVMLTIEDNGAGIIDKDINRVLEKGFTGENGRKFSKGTGMGLYL
CCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
CEKLCSKLGLRISIDSEVNRGTKVTLIFPLSSMITFTDY
HHHHHHHCCCEEEECCCCCCCCEEEEEEEHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 8867804 [H]