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The map label for this gene is mcpB [H]

Identifier: 226949298

GI number: 226949298

Start: 2283848

End: 2285497

Strand: Reverse

Name: mcpB [H]

Synonym: CLM_2217

Alternate gene names: 226949298

Gene position: 2285497-2283848 (Counterclockwise)

Preceding gene: 226949299

Following gene: 226949297

Centisome position: 55.0

GC content: 30.06

Gene sequence:

>1650_bases
ATGTTAAATAGTTTTAAGAAAAAAATATTGGCAGGGTTTTTGTTAGTAACTTTATTGTGTGTTGTTTCTCTGACCACAGT
ATCATTATTAGAGGCTAGAAAAATAGCTACTAATCAAATGAAAAAAGATGGTATTGCCATAAGTAATATGGTAAGAAAAT
CTTTAGGTAAAAATAAAATAACTGATACAAAAGAAATGAGTACTATATTAAAGGAAATAAAAAAAGAGTTAAAAGAAGAT
ATGGTGTATTTATCAGTGTGTAATACAAATTATAAAGTAATTGCTCATAATGATGACAATATGATAAATACTGGAATAGA
GAATAAAGAACAATTTGAAAATATACTCAAAGAAGGAAAAACTATAGGATTAATATTTAAAAGAACAACTGGAGATAAGG
TATATAATGTATCCACCCCATTTTATGAGGATGGGAAAGTAGTAGGCATTATAAATGTAGGAATCTCCCTTGAAGGTATG
AATAAGTTAATAAAAAAAGGTCTTATTGAAACATTGGGTATAGCCTTGGTAATATTAGTAATTTCCTTTATTATAGCTAT
TTTAATTGCAAGAAATATATCAAAGCCTATAGAAAGTATGGTAACTAAAGTGAATCGAGTTTCTGCGGGGGACTTTACTG
TAGAATTTCATGCAAAAGGTGACGATGAGATTTCGAAATTAATGAGTTCTTTAAATAAAACTATGGAAGTTATAAGAAAT
CTTATAGGTAAGATTAAAGATGAAGTAATTACTATAGATGGAGTTTCTCAAAATTTATCTTCATCCAGTGAAGAAAACTC
TGCTTCAACTACTCAGGTTTCAAATTCATTAGCAGAGGTTGCAGAAAGCTCTACAAATCAAGCACAGCAAATCAATGAAG
CTACTGAAGCTCTTATGAGATTTGGAGAACTTCTAGAAAATGTAAATGATAAAGTTATAGATGTAGCCAGTAGCAGTTCA
AATATAAAAAATTCTGCCCATGAGGGTTCTATAAAGATAGACAACCTTGTTAAATCTGTAGAAGACATTAAGGAAAACTT
TCTATCTGTTACAGATAGAATTTCTTCATTAAGTGGTAGTGTTCTTAAAATAAGTGAAATTACAGATGTTATAAATAAAA
TAGCTGAAAAAACTAATCTTTTAGCCTTAAATGCTGCTATAGAAGCAGCTAGAGCTGGCGAAGCTGGAAGAGGTTTTTCA
GTGGTGGCAGAAGAAATAAGAAAACTTGCAGAACAGGTTTTATATTCCTCTAAGAATATACATACATTAGTTGAAACTGT
AACAACTAATACAAATGAAGTTTCTTATAATACTGAAAAAGTATCAGAAAAAATACAAGTACAGGCAAATTCCATAGAAG
ATACTATAGATTCTTTTAAAAATATATTAGGAGAAGTAGAAAAGATTACTCCTGAAGTTAAAGAAGTATCCCAAAAATTA
AATATGACTATGGATAAAAAAGATACTATTCTTAATAATGTGGGAACAGTATCTAATATATCTCAAGAACTTTCAGCATC
TACAGAAGAGATTGCTGCGGCCATGGAACAACAAGCTTCTTCTACAGAAGAAGTATCCTCTTCTGCCGAGGAGCTTACAG
AACTAGCAGATAGGTTAGCAACCTTAGTATCAAACCTAAAAACAGAATAG

Upstream 100 bases:

>100_bases
GTATAGATAATGTTAGTATACTTGAAAAAATTTATAAGAGTATTATAATTATAGAAGTTAAGACAGTAATAGATAAAATA
GACAAAAGTAGGTGTAATTT

Downstream 100 bases:

>100_bases
GGGGACGGCTTATAAAAATTAATAATTTATAATGATTTTAAAAGGATCGGTTCATAGGGAATAGATAAGAATGTAATACA
AAAGCATAGAAAAATTGAAT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MLNSFKKKILAGFLLVTLLCVVSLTTVSLLEARKIATNQMKKDGIAISNMVRKSLGKNKITDTKEMSTILKEIKKELKED
MVYLSVCNTNYKVIAHNDDNMINTGIENKEQFENILKEGKTIGLIFKRTTGDKVYNVSTPFYEDGKVVGIINVGISLEGM
NKLIKKGLIETLGIALVILVISFIIAILIARNISKPIESMVTKVNRVSAGDFTVEFHAKGDDEISKLMSSLNKTMEVIRN
LIGKIKDEVITIDGVSQNLSSSSEENSASTTQVSNSLAEVAESSTNQAQQINEATEALMRFGELLENVNDKVIDVASSSS
NIKNSAHEGSIKIDNLVKSVEDIKENFLSVTDRISSLSGSVLKISEITDVINKIAEKTNLLALNAAIEAARAGEAGRGFS
VVAEEIRKLAEQVLYSSKNIHTLVETVTTNTNEVSYNTEKVSEKIQVQANSIEDTIDSFKNILGEVEKITPEVKEVSQKL
NMTMDKKDTILNNVGTVSNISQELSASTEEIAAAMEQQASSTEEVSSSAEELTELADRLATLVSNLKTE

Sequences:

>Translated_549_residues
MLNSFKKKILAGFLLVTLLCVVSLTTVSLLEARKIATNQMKKDGIAISNMVRKSLGKNKITDTKEMSTILKEIKKELKED
MVYLSVCNTNYKVIAHNDDNMINTGIENKEQFENILKEGKTIGLIFKRTTGDKVYNVSTPFYEDGKVVGIINVGISLEGM
NKLIKKGLIETLGIALVILVISFIIAILIARNISKPIESMVTKVNRVSAGDFTVEFHAKGDDEISKLMSSLNKTMEVIRN
LIGKIKDEVITIDGVSQNLSSSSEENSASTTQVSNSLAEVAESSTNQAQQINEATEALMRFGELLENVNDKVIDVASSSS
NIKNSAHEGSIKIDNLVKSVEDIKENFLSVTDRISSLSGSVLKISEITDVINKIAEKTNLLALNAAIEAARAGEAGRGFS
VVAEEIRKLAEQVLYSSKNIHTLVETVTTNTNEVSYNTEKVSEKIQVQANSIEDTIDSFKNILGEVEKITPEVKEVSQKL
NMTMDKKDTILNNVGTVSNISQELSASTEEIAAAMEQQASSTEEVSSSAEELTELADRLATLVSNLKTE
>Mature_549_residues
MLNSFKKKILAGFLLVTLLCVVSLTTVSLLEARKIATNQMKKDGIAISNMVRKSLGKNKITDTKEMSTILKEIKKELKED
MVYLSVCNTNYKVIAHNDDNMINTGIENKEQFENILKEGKTIGLIFKRTTGDKVYNVSTPFYEDGKVVGIINVGISLEGM
NKLIKKGLIETLGIALVILVISFIIAILIARNISKPIESMVTKVNRVSAGDFTVEFHAKGDDEISKLMSSLNKTMEVIRN
LIGKIKDEVITIDGVSQNLSSSSEENSASTTQVSNSLAEVAESSTNQAQQINEATEALMRFGELLENVNDKVIDVASSSS
NIKNSAHEGSIKIDNLVKSVEDIKENFLSVTDRISSLSGSVLKISEITDVINKIAEKTNLLALNAAIEAARAGEAGRGFS
VVAEEIRKLAEQVLYSSKNIHTLVETVTTNTNEVSYNTEKVSEKIQVQANSIEDTIDSFKNILGEVEKITPEVKEVSQKL
NMTMDKKDTILNNVGTVSNISQELSASTEEIAAAMEQQASSTEEVSSSAEELTELADRLATLVSNLKTE

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=376, Percent_Identity=28.4574468085106, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI2367378, Length=261, Percent_Identity=28.3524904214559, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788194, Length=371, Percent_Identity=24.7978436657682, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789453, Length=375, Percent_Identity=24.5333333333333, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788195, Length=284, Percent_Identity=25, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 59929; Mature: 59929

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSFKKKILAGFLLVTLLCVVSLTTVSLLEARKIATNQMKKDGIAISNMVRKSLGKNKI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
TDTKEMSTILKEIKKELKEDMVYLSVCNTNYKVIAHNDDNMINTGIENKEQFENILKEGK
CCHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCC
TIGLIFKRTTGDKVYNVSTPFYEDGKVVGIINVGISLEGMNKLIKKGLIETLGIALVILV
EEEEEEEECCCCEEEECCCCCCCCCCEEEEEEECEEHHHHHHHHHHHHHHHHHHHHHHHH
ISFIIAILIARNISKPIESMVTKVNRVSAGDFTVEFHAKGDDEISKLMSSLNKTMEVIRN
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
LIGKIKDEVITIDGVSQNLSSSSEENSASTTQVSNSLAEVAESSTNQAQQINEATEALMR
HHHHHHHCEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FGELLENVNDKVIDVASSSSNIKNSAHEGSIKIDNLVKSVEDIKENFLSVTDRISSLSGS
HHHHHHCCCHHEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VLKISEITDVINKIAEKTNLLALNAAIEAARAGEAGRGFSVVAEEIRKLAEQVLYSSKNI
EEHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCH
HTLVETVTTNTNEVSYNTEKVSEKIQVQANSIEDTIDSFKNILGEVEKITPEVKEVSQKL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
NMTMDKKDTILNNVGTVSNISQELSASTEEIAAAMEQQASSTEEVSSSAEELTELADRLA
CCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TLVSNLKTE
HHHHHHCCC
>Mature Secondary Structure
MLNSFKKKILAGFLLVTLLCVVSLTTVSLLEARKIATNQMKKDGIAISNMVRKSLGKNKI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
TDTKEMSTILKEIKKELKEDMVYLSVCNTNYKVIAHNDDNMINTGIENKEQFENILKEGK
CCHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCC
TIGLIFKRTTGDKVYNVSTPFYEDGKVVGIINVGISLEGMNKLIKKGLIETLGIALVILV
EEEEEEEECCCCEEEECCCCCCCCCCEEEEEEECEEHHHHHHHHHHHHHHHHHHHHHHHH
ISFIIAILIARNISKPIESMVTKVNRVSAGDFTVEFHAKGDDEISKLMSSLNKTMEVIRN
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
LIGKIKDEVITIDGVSQNLSSSSEENSASTTQVSNSLAEVAESSTNQAQQINEATEALMR
HHHHHHHCEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FGELLENVNDKVIDVASSSSNIKNSAHEGSIKIDNLVKSVEDIKENFLSVTDRISSLSGS
HHHHHHCCCHHEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VLKISEITDVINKIAEKTNLLALNAAIEAARAGEAGRGFSVVAEEIRKLAEQVLYSSKNI
EEHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCH
HTLVETVTTNTNEVSYNTEKVSEKIQVQANSIEDTIDSFKNILGEVEKITPEVKEVSQKL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
NMTMDKKDTILNNVGTVSNISQELSASTEEIAAAMEQQASSTEEVSSSAEELTELADRLA
CCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TLVSNLKTE
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]