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The map label for this gene is efp

Identifier: 226949195

GI number: 226949195

Start: 2167856

End: 2168413

Strand: Reverse

Name: efp

Synonym: CLM_2114

Alternate gene names: 226949195

Gene position: 2168413-2167856 (Counterclockwise)

Preceding gene: 226949196

Following gene: 226949194

Centisome position: 52.18

GC content: 31.72

Gene sequence:

>558_bases
ATGATATCAGCAGGAGATTTAAGAAAAGGAACTACTTTTGAACAAGATGGACAAGTATACGTAGTTGTAGAATTCCTACA
TGTAAAACCAGGTAAAGGAGCGGCTTTCGTAAGAACTAAGTTAAAGAATGCCATAACTGGAGCTGTAACAGAAACAACTT
TTAACCCAACTGCAAAACTTCAAGAAGCAGTTATTGAAAGAAAAGAAATGCAATATTTATATACCGATGGAGAATTATAT
TATTTCATGGATCAAGAAACTTTTGAACAAATTCCATTAAATTATGATAAAGTTGAAGAAGCTATAAAATTCTTAAAAGA
AAATATGTTCGCTACAATAAAATTCTTTAAAGGAGAAGCTTTCTCAGTAGAAGCACCAAACTTTGTTGAATTACTTATAT
CTCATACAGAACCAGGTGCAAAAGGAAATACTACTAGTAATGTAATGAAACCAGCTACATTAGAAACTGGAGCTACAATT
CAAGTTCCATTATTCGTAAATGAAGGAGAAACTATCAGAGTAGATACAAGAACTGGTGAATATATGGAAAGAGTTTAG

Upstream 100 bases:

>100_bases
AGGGAAAAATAACATTGTAGTACATTAAAAAATTTGGTATATAAGGCCTTACAAAGGTTATAATATAAAAAGGAATATTT
AGTTTTGGAGGGATACATAA

Downstream 100 bases:

>100_bases
TCTATACTATAGATAGTATAATTTGTAAGGATGTGATTTTGTGAAATCTATTACTTCAAAGGTATCCTATTTAAAAGGCC
TTATAGAAGGTCTAGAGGTT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MISAGDLRKGTTFEQDGQVYVVVEFLHVKPGKGAAFVRTKLKNAITGAVTETTFNPTAKLQEAVIERKEMQYLYTDGELY
YFMDQETFEQIPLNYDKVEEAIKFLKENMFATIKFFKGEAFSVEAPNFVELLISHTEPGAKGNTTSNVMKPATLETGATI
QVPLFVNEGETIRVDTRTGEYMERV

Sequences:

>Translated_185_residues
MISAGDLRKGTTFEQDGQVYVVVEFLHVKPGKGAAFVRTKLKNAITGAVTETTFNPTAKLQEAVIERKEMQYLYTDGELY
YFMDQETFEQIPLNYDKVEEAIKFLKENMFATIKFFKGEAFSVEAPNFVELLISHTEPGAKGNTTSNVMKPATLETGATI
QVPLFVNEGETIRVDTRTGEYMERV
>Mature_185_residues
MISAGDLRKGTTFEQDGQVYVVVEFLHVKPGKGAAFVRTKLKNAITGAVTETTFNPTAKLQEAVIERKEMQYLYTDGELY
YFMDQETFEQIPLNYDKVEEAIKFLKENMFATIKFFKGEAFSVEAPNFVELLISHTEPGAKGNTTSNVMKPATLETGATI
QVPLFVNEGETIRVDTRTGEYMERV

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=44.5054945054945, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=30.8510638297872, Blast_Score=95, Evalue=3e-21,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_CLOB1 (A7FUV2)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001384155.1
- ProteinModelPortal:   A7FUV2
- SMR:   A7FUV2
- STRING:   A7FUV2
- GeneID:   5394638
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_1834
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   CBOT441770:CLB_1834-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20828; Mature: 20828

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISAGDLRKGTTFEQDGQVYVVVEFLHVKPGKGAAFVRTKLKNAITGAVTETTFNPTAKL
CCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCEEECCCCCHHHH
QEAVIERKEMQYLYTDGELYYFMDQETFEQIPLNYDKVEEAIKFLKENMFATIKFFKGEA
HHHHHHHHHEEEEEECCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHCCEEEEEEECCCE
FSVEAPNFVELLISHTEPGAKGNTTSNVMKPATLETGATIQVPLFVNEGETIRVDTRTGE
EEECCCHHHHHEEECCCCCCCCCCCCCCCCCCEECCCCEEEEEEEECCCCEEEEECCCCH
YMERV
HHHCC
>Mature Secondary Structure
MISAGDLRKGTTFEQDGQVYVVVEFLHVKPGKGAAFVRTKLKNAITGAVTETTFNPTAKL
CCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCEEECCCCCHHHH
QEAVIERKEMQYLYTDGELYYFMDQETFEQIPLNYDKVEEAIKFLKENMFATIKFFKGEA
HHHHHHHHHEEEEEECCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHCCEEEEEEECCCE
FSVEAPNFVELLISHTEPGAKGNTTSNVMKPATLETGATIQVPLFVNEGETIRVDTRTGE
EEECCCHHHHHEEECCCCCCCCCCCCCCCCCCEECCCCEEEEEEEECCCCEEEEECCCCH
YMERV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA