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The map label for this gene is yafV [C]

Identifier: 226949062

GI number: 226949062

Start: 2042886

End: 2043722

Strand: Reverse

Name: yafV [C]

Synonym: CLM_1978

Alternate gene names: 226949062

Gene position: 2043722-2042886 (Counterclockwise)

Preceding gene: 226949063

Following gene: 226949061

Centisome position: 49.18

GC content: 30.11

Gene sequence:

>837_bases
ATGGATAAGTTAAAAATAGCTTTATGCCAAATGCAAGTTCAAAAGGAAAAGAAAAAAAATATAAAAAAAGCTATAGAAAT
GCTAACAAAAGCTAAAAAAGAAAACTGTAACATAGTAGTTCTACCGGAAATGTTCAATTGCCCCTATGAAAATAAATGTT
TTAAACCTTATGGAGAAATAATAAATGAAGAAAATGGGGGAGAAACTGTAAAAGCTATAAAAAAAGCTGCAAAAGATTTA
GAGCTTTATATTGTAGCAGGTTCTATTCCTGAAATAGAAGGGGATAAAATTTATAATACATCTATGGTATTTGACAATAA
AGGTGTTTTAATAGCTAAGCATAGAAAAGTTCACTTATTTGATATAGATGTAAAAGGGGGAGTGACCTTTAAAGAATCTG
ATACATTGACTGCTGGAAATAAAATAACACTCTTTAACACTCCCTGGGGTAAATTAGGGGTAATGATATGTTACGATATA
AGATTCCCAGAACTTTCAAGAATAATGGCTGTTAAGGGGGCTAAAATTATATTTACTCCAGCAGCTTTTAATATGACTAC
AGGGCCTGCTCATTGGGATACTTTATTTAAAAGTAGAGCATTAGATAATCAAGTCTATATGGTAGGTGTAGCACCTGCTA
GGGATGAAAATAGTAATTATGTATCTTATGGCAATTCATTAATTGCTAGCCCTTGGGGAAATATACTAGCTAAATTAGAT
GCAAAAGAAGATATACTTTTTTCAGAAATAGATTTAGACTATGAAAGTAAAATAAGAGAAGAACTACCTCTATTAAAACA
TATAAGAAAAGACATATATAGTTTAGCAGAAATTTAA

Upstream 100 bases:

>100_bases
AATTATATTATAATCGAACTAATACTATATCTATATTATACTTTTTAATATTTTCTTAAATTAATAAGCTTGTTATAATA
ATTTAAGCTGGAGGAGTTTT

Downstream 100 bases:

>100_bases
TTTAGCAATCTAAATAATTGTATGTTAAAATTGAAATAGCCTTCAGAGAAGTTATATTCTTTGAAGGTTATTTTGAAATT
TTTACATTATATTATGAAGC

Product: hydrolase, carbon-nitrogen family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MDKLKIALCQMQVQKEKKKNIKKAIEMLTKAKKENCNIVVLPEMFNCPYENKCFKPYGEIINEENGGETVKAIKKAAKDL
ELYIVAGSIPEIEGDKIYNTSMVFDNKGVLIAKHRKVHLFDIDVKGGVTFKESDTLTAGNKITLFNTPWGKLGVMICYDI
RFPELSRIMAVKGAKIIFTPAAFNMTTGPAHWDTLFKSRALDNQVYMVGVAPARDENSNYVSYGNSLIASPWGNILAKLD
AKEDILFSEIDLDYESKIREELPLLKHIRKDIYSLAEI

Sequences:

>Translated_278_residues
MDKLKIALCQMQVQKEKKKNIKKAIEMLTKAKKENCNIVVLPEMFNCPYENKCFKPYGEIINEENGGETVKAIKKAAKDL
ELYIVAGSIPEIEGDKIYNTSMVFDNKGVLIAKHRKVHLFDIDVKGGVTFKESDTLTAGNKITLFNTPWGKLGVMICYDI
RFPELSRIMAVKGAKIIFTPAAFNMTTGPAHWDTLFKSRALDNQVYMVGVAPARDENSNYVSYGNSLIASPWGNILAKLD
AKEDILFSEIDLDYESKIREELPLLKHIRKDIYSLAEI
>Mature_278_residues
MDKLKIALCQMQVQKEKKKNIKKAIEMLTKAKKENCNIVVLPEMFNCPYENKCFKPYGEIINEENGGETVKAIKKAAKDL
ELYIVAGSIPEIEGDKIYNTSMVFDNKGVLIAKHRKVHLFDIDVKGGVTFKESDTLTAGNKITLFNTPWGKLGVMICYDI
RFPELSRIMAVKGAKIIFTPAAFNMTTGPAHWDTLFKSRALDNQVYMVGVAPARDENSNYVSYGNSLIASPWGNILAKLD
AKEDILFSEIDLDYESKIREELPLLKHIRKDIYSLAEI

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=275, Percent_Identity=44, Blast_Score=276, Evalue=1e-74,
Organism=Homo sapiens, GI5031947, Length=278, Percent_Identity=32.7338129496403, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI297632348, Length=274, Percent_Identity=32.4817518248175, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI297632350, Length=274, Percent_Identity=32.4817518248175, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI297632346, Length=198, Percent_Identity=32.8282828282828, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI7706509, Length=242, Percent_Identity=25.2066115702479, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17556280, Length=280, Percent_Identity=35.3571428571429, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17533173, Length=303, Percent_Identity=24.4224422442244, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323383, Length=277, Percent_Identity=44.043321299639, Blast_Score=253, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6322335, Length=301, Percent_Identity=29.2358803986711, Blast_Score=145, Evalue=7e-36,
Organism=Drosophila melanogaster, GI21355835, Length=273, Percent_Identity=43.956043956044, Blast_Score=255, Evalue=2e-68,
Organism=Drosophila melanogaster, GI17933642, Length=272, Percent_Identity=35.2941176470588, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI21358471, Length=271, Percent_Identity=27.6752767527675, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 31377; Mature: 31377

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLKIALCQMQVQKEKKKNIKKAIEMLTKAKKENCNIVVLPEMFNCPYENKCFKPYGEI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHCCCCCCCCCCHHHHH
INEENGGETVKAIKKAAKDLELYIVAGSIPEIEGDKIYNTSMVFDNKGVLIAKHRKVHLF
HCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEEEEECCCCEEEEECCEEEEE
DIDVKGGVTFKESDTLTAGNKITLFNTPWGKLGVMICYDIRFPELSRIMAVKGAKIIFTP
EEEECCCEEECCCCCEECCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHCCCCEEEEEC
AAFNMTTGPAHWDTLFKSRALDNQVYMVGVAPARDENSNYVSYGNSLIASPWGNILAKLD
CCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCEEEECCHHHHHEECC
AKEDILFSEIDLDYESKIREELPLLKHIRKDIYSLAEI
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKLKIALCQMQVQKEKKKNIKKAIEMLTKAKKENCNIVVLPEMFNCPYENKCFKPYGEI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHCCCCCCCCCCHHHHH
INEENGGETVKAIKKAAKDLELYIVAGSIPEIEGDKIYNTSMVFDNKGVLIAKHRKVHLF
HCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEEEEECCCCEEEEECCEEEEE
DIDVKGGVTFKESDTLTAGNKITLFNTPWGKLGVMICYDIRFPELSRIMAVKGAKIIFTP
EEEECCCEEECCCCCEECCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHCCCCEEEEEC
AAFNMTTGPAHWDTLFKSRALDNQVYMVGVAPARDENSNYVSYGNSLIASPWGNILAKLD
CCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCEEEECCHHHHHEECC
AKEDILFSEIDLDYESKIREELPLLKHIRKDIYSLAEI
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]