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The map label for this gene is lacF [H]

Identifier: 226948849

GI number: 226948849

Start: 1789326

End: 1790219

Strand: Direct

Name: lacF [H]

Synonym: CLM_1751

Alternate gene names: 226948849

Gene position: 1789326-1790219 (Clockwise)

Preceding gene: 226948848

Following gene: 226948850

Centisome position: 43.06

GC content: 26.17

Gene sequence:

>894_bases
GTGAATAATAATAAAAACTTAAAATCCTTTGTAAAAGGTATTATGTATATAGCACCAGCTCTTGGACTACTTTTAATTTT
TAATATTTATCCTATAATAAAATCCTTTGATATGAGCTTTTATACTCGGTATAACTACTATAAGGATATAGTTTATGCTA
GGGGATTAGATAATTTTTATTACATATTTAGTGATAAAGAATTTTTAATAGCTATGAAAAATACTTTTATATATGTGCTT
TATGTTATGCCTATATCTATTATTTTGTCATTGATAATTGCTATTTTGTTAAATTCAAATATAAAATTTAGAGGTTTTTT
TAGAACTGTATATTTTATACCCTTTATAACATCAACAGTAGCCATATCTATGGTTTGGAGATGGATGTATCATGCGGATC
ATGGAATTCTAAATTATTTATTACAAGTAATAGGATTATCTCCTGTTAAGTGGCTTTCAGATCCTAAATGGGCTATGCCT
AGTTTAATTATATTAAGTATATGGAAAAGTCTTGGTTACAATATAGTCATATTTTTAGCAGGACTTCAAAATATAGATGA
GCAGTATAATTTAGCAGCTAAATTAGATGGAGCTAATAAGTGGGAAAGAATCAAAAATATAACTGTACCACTTTTATCAC
CAACTATATTTTTTGTATGCATAATGACTTTGATAAGCTCTTTTAAGGTTTTTGGAGAAATATTTGCCTTGTTTGATAAG
CAACCTGGACCATTAAATACTTGCCTTACTATGGTATATTACATATACAACAAATTTTATAATCAGTATCAATATGGCAT
TGCATCTGCTGCAGTATTTGTTCTTTTTATAATAATAAGCCTATTTAACTTTATTCAATTTTATATAGGAAAGAAAAAAG
TAGAATATCATTAA

Upstream 100 bases:

>100_bases
AATAAAAATGAAAAAACAGTATATCTAAATATAAAAAAATATAAGGTGCATTTTTTTAGTTTTCAAGATGAAAAAAATAT
ATTAATTAAAGGTGAAGAAA

Downstream 100 bases:

>100_bases
ATTATCTAGAGCATATTATGCAAGGAGATTATATTATGACAAAAAATATTTTAAAGAAATCTTTGATTTATATCATATTA
GTATTAGGATGTATTATTAC

Product: carbohydrate uptake ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNNNKNLKSFVKGIMYIAPALGLLLIFNIYPIIKSFDMSFYTRYNYYKDIVYARGLDNFYYIFSDKEFLIAMKNTFIYVL
YVMPISIILSLIIAILLNSNIKFRGFFRTVYFIPFITSTVAISMVWRWMYHADHGILNYLLQVIGLSPVKWLSDPKWAMP
SLIILSIWKSLGYNIVIFLAGLQNIDEQYNLAAKLDGANKWERIKNITVPLLSPTIFFVCIMTLISSFKVFGEIFALFDK
QPGPLNTCLTMVYYIYNKFYNQYQYGIASAAVFVLFIIISLFNFIQFYIGKKKVEYH

Sequences:

>Translated_297_residues
MNNNKNLKSFVKGIMYIAPALGLLLIFNIYPIIKSFDMSFYTRYNYYKDIVYARGLDNFYYIFSDKEFLIAMKNTFIYVL
YVMPISIILSLIIAILLNSNIKFRGFFRTVYFIPFITSTVAISMVWRWMYHADHGILNYLLQVIGLSPVKWLSDPKWAMP
SLIILSIWKSLGYNIVIFLAGLQNIDEQYNLAAKLDGANKWERIKNITVPLLSPTIFFVCIMTLISSFKVFGEIFALFDK
QPGPLNTCLTMVYYIYNKFYNQYQYGIASAAVFVLFIIISLFNFIQFYIGKKKVEYH
>Mature_297_residues
MNNNKNLKSFVKGIMYIAPALGLLLIFNIYPIIKSFDMSFYTRYNYYKDIVYARGLDNFYYIFSDKEFLIAMKNTFIYVL
YVMPISIILSLIIAILLNSNIKFRGFFRTVYFIPFITSTVAISMVWRWMYHADHGILNYLLQVIGLSPVKWLSDPKWAMP
SLIILSIWKSLGYNIVIFLAGLQNIDEQYNLAAKLDGANKWERIKNITVPLLSPTIFFVCIMTLISSFKVFGEIFALFDK
QPGPLNTCLTMVYYIYNKFYNQYQYGIASAAVFVLFIIISLFNFIQFYIGKKKVEYH

Specific function: Part of the binding-protein-dependent transport system for lactose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787570, Length=245, Percent_Identity=28.1632653061224, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789861, Length=289, Percent_Identity=24.9134948096886, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1790465, Length=256, Percent_Identity=21.875, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34728; Mature: 34728

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNKNLKSFVKGIMYIAPALGLLLIFNIYPIIKSFDMSFYTRYNYYKDIVYARGLDNFY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEE
YIFSDKEFLIAMKNTFIYVLYVMPISIILSLIIAILLNSNIKFRGFFRTVYFIPFITSTV
EEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AISMVWRWMYHADHGILNYLLQVIGLSPVKWLSDPKWAMPSLIILSIWKSLGYNIVIFLA
HHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEH
GLQNIDEQYNLAAKLDGANKWERIKNITVPLLSPTIFFVCIMTLISSFKVFGEIFALFDK
HHHHHHHHHCHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QPGPLNTCLTMVYYIYNKFYNQYQYGIASAAVFVLFIIISLFNFIQFYIGKKKVEYH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNNNKNLKSFVKGIMYIAPALGLLLIFNIYPIIKSFDMSFYTRYNYYKDIVYARGLDNFY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEE
YIFSDKEFLIAMKNTFIYVLYVMPISIILSLIIAILLNSNIKFRGFFRTVYFIPFITSTV
EEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AISMVWRWMYHADHGILNYLLQVIGLSPVKWLSDPKWAMPSLIILSIWKSLGYNIVIFLA
HHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEH
GLQNIDEQYNLAAKLDGANKWERIKNITVPLLSPTIFFVCIMTLISSFKVFGEIFALFDK
HHHHHHHHHCHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QPGPLNTCLTMVYYIYNKFYNQYQYGIASAAVFVLFIIISLFNFIQFYIGKKKVEYH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1630315 [H]