Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 226948806

GI number: 226948806

Start: 1741815

End: 1742903

Strand: Direct

Name: aroB [H]

Synonym: CLM_1707

Alternate gene names: 226948806

Gene position: 1741815-1742903 (Clockwise)

Preceding gene: 226948805

Following gene: 226948807

Centisome position: 41.92

GC content: 25.71

Gene sequence:

>1089_bases
ATGAAAGAAATAATATTAGAAAGTTTAGAACTTAAACATAGGGTATACATAAATAATAACTTAAATAGATTTCACAATAT
ACTTTTAGAAAATAGGATAAAGGATAGCGATAGTATATTTATAATAACAGACGAAAATGTATATAACTTATATAAACATA
AAATGGAACAGTTTATAAATAAAAATAAGTATTTTGTATTTGTCATGGAACCAGGGGAAGAAAATAAAAATATTAATACA
ATAAATAAAATATATGATTTTTTAATGGATAATAATGCTAATAGACATAGTGTATTAATAGCTTTTGGTGGAGGAATAGT
AGGAGATATTACAGGATTTGTAGCATCTACATATATGAGGGGGTTACGTTTTATAAATATACCTACTACCCTATTAGCTC
AAGTAGACAGCTCAATAGGAGGAAAAGTAGGATATAACCATAGAGAAATAAAAAACTTAATAGGTAATTTTTACAATCCA
GTCTTTGTTTATGTTAGTACTAGTTTTTTAAAAACTTTAAGTAAAAGGGAGTTTTTAAATGGATTAGGAGAAATAATAAA
ATATTCTTTAATAAGGGAGAATGATTTAGCTTATTTTATAGAAAAGAATATTAAATTTATATTAGAAAGAGAGCAAGATA
AGCTTATTCATATAGTGAAGGAATGTCTATCTATAAAAGCAGCTATTGTAGAAGAAGACTTTAGGGATTTAGGTATGAGG
AATTCCTTAAATTTTGGTCATACCGTAGGGCATGCAATAGAAGCTAATTCTAGTTACAGGATATCTCATGGAGAAGCAGT
GGCTTTAGGTATACTAGTAGCCTTAAAATTGTCAGAAAAAAAGCTAAATCTAGATAAAAACATATATAATAATGTAGTAC
AGTTATATAAAAAGTTAAATTTACCACTTTTCTATAAAGTTGACAACTATAAAACATTTTTGTATGCTATAAGACATGAT
AAAAAAAATAGAGAAAAAATTAGATTTGCTTTACTAGAGGAAGTAGGTAAAGTAAAGGTAAAAGTAGAAGTAGAAGAAAA
TGAGATTATTAAAGCTATAAAAGAAAGTATAGATAGGGAGGAAAAATAA

Upstream 100 bases:

>100_bases
ATTTTTATAGGTTATTCTAAAGTTTCATAGAGAAGCATTTGTTATAATAGCAATTTACAATGATTTCAGAATTACTTTAT
ATATGAAAGTAGGTGAATTT

Downstream 100 bases:

>100_bases
ATGACAATAGGTATTATAGGTGCAATGGATGAGGAATTAGAATTATTATTAAAGGAATTAGATTTGGAAAAAAAGCAAGT
TAAAGCCAATATGACATTTA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKEIILESLELKHRVYINNNLNRFHNILLENRIKDSDSIFIITDENVYNLYKHKMEQFINKNKYFVFVMEPGEENKNINT
INKIYDFLMDNNANRHSVLIAFGGGIVGDITGFVASTYMRGLRFINIPTTLLAQVDSSIGGKVGYNHREIKNLIGNFYNP
VFVYVSTSFLKTLSKREFLNGLGEIIKYSLIRENDLAYFIEKNIKFILEREQDKLIHIVKECLSIKAAIVEEDFRDLGMR
NSLNFGHTVGHAIEANSSYRISHGEAVALGILVALKLSEKKLNLDKNIYNNVVQLYKKLNLPLFYKVDNYKTFLYAIRHD
KKNREKIRFALLEEVGKVKVKVEVEENEIIKAIKESIDREEK

Sequences:

>Translated_362_residues
MKEIILESLELKHRVYINNNLNRFHNILLENRIKDSDSIFIITDENVYNLYKHKMEQFINKNKYFVFVMEPGEENKNINT
INKIYDFLMDNNANRHSVLIAFGGGIVGDITGFVASTYMRGLRFINIPTTLLAQVDSSIGGKVGYNHREIKNLIGNFYNP
VFVYVSTSFLKTLSKREFLNGLGEIIKYSLIRENDLAYFIEKNIKFILEREQDKLIHIVKECLSIKAAIVEEDFRDLGMR
NSLNFGHTVGHAIEANSSYRISHGEAVALGILVALKLSEKKLNLDKNIYNNVVQLYKKLNLPLFYKVDNYKTFLYAIRHD
KKNREKIRFALLEEVGKVKVKVEVEENEIIKAIKESIDREEK
>Mature_362_residues
MKEIILESLELKHRVYINNNLNRFHNILLENRIKDSDSIFIITDENVYNLYKHKMEQFINKNKYFVFVMEPGEENKNINT
INKIYDFLMDNNANRHSVLIAFGGGIVGDITGFVASTYMRGLRFINIPTTLLAQVDSSIGGKVGYNHREIKNLIGNFYNP
VFVYVSTSFLKTLSKREFLNGLGEIIKYSLIRENDLAYFIEKNIKFILEREQDKLIHIVKECLSIKAAIVEEDFRDLGMR
NSLNFGHTVGHAIEANSSYRISHGEAVALGILVALKLSEKKLNLDKNIYNNVVQLYKKLNLPLFYKVDNYKTFLYAIRHD
KKNREKIRFALLEEVGKVKVKVEVEENEIIKAIKESIDREEK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=329, Percent_Identity=35.258358662614, Blast_Score=210, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6320332, Length=360, Percent_Identity=33.0555555555556, Blast_Score=179, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 42054; Mature: 42054

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIILESLELKHRVYINNNLNRFHNILLENRIKDSDSIFIITDENVYNLYKHKMEQFIN
CHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHC
KNKYFVFVMEPGEENKNINTINKIYDFLMDNNANRHSVLIAFGGGIVGDITGFVASTYMR
CCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
GLRFINIPTTLLAQVDSSIGGKVGYNHREIKNLIGNFYNPVFVYVSTSFLKTLSKREFLN
CCEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHH
GLGEIIKYSLIRENDLAYFIEKNIKFILEREQDKLIHIVKECLSIKAAIVEEDFRDLGMR
HHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NSLNFGHTVGHAIEANSSYRISHGEAVALGILVALKLSEKKLNLDKNIYNNVVQLYKKLN
CCCCCCCHHCCEEECCCCEEECCCCHHHHHHHHHHEECCHHCCCCHHHHHHHHHHHHHCC
LPLFYKVDNYKTFLYAIRHDKKNREKIRFALLEEVGKVKVKVEVEENEIIKAIKESIDRE
CCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHCCC
EK
CC
>Mature Secondary Structure
MKEIILESLELKHRVYINNNLNRFHNILLENRIKDSDSIFIITDENVYNLYKHKMEQFIN
CHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHC
KNKYFVFVMEPGEENKNINTINKIYDFLMDNNANRHSVLIAFGGGIVGDITGFVASTYMR
CCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
GLRFINIPTTLLAQVDSSIGGKVGYNHREIKNLIGNFYNPVFVYVSTSFLKTLSKREFLN
CCEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHH
GLGEIIKYSLIRENDLAYFIEKNIKFILEREQDKLIHIVKECLSIKAAIVEEDFRDLGMR
HHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NSLNFGHTVGHAIEANSSYRISHGEAVALGILVALKLSEKKLNLDKNIYNNVVQLYKKLN
CCCCCCCHHCCEEECCCCEEECCCCHHHHHHHHHHEECCHHCCCCHHHHHHHHHHHHHCC
LPLFYKVDNYKTFLYAIRHDKKNREKIRFALLEEVGKVKVKVEVEENEIIKAIKESIDRE
CCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHCCC
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]