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The map label for this gene is mraW [H]

Identifier: 226948790

GI number: 226948790

Start: 1726513

End: 1727442

Strand: Direct

Name: mraW [H]

Synonym: CLM_1691

Alternate gene names: 226948790

Gene position: 1726513-1727442 (Clockwise)

Preceding gene: 226948789

Following gene: 226948791

Centisome position: 41.55

GC content: 28.06

Gene sequence:

>930_bases
ATGGAATTTAAACATATATCTGTATTATTAGAAGAGACTATAGATTCACTTAATATAAAGGAAGATGGTGTATATGTAGA
CTGTACTTTAGGTGGTGGAGGACATTCTAAAGAAATATTAAAAAAATTATCCCACAAGGGAAAATTAATAGGCATAGATC
AAGATACAAGTGCTATTAAAGCAGCTAAAGAAAGATTAAAAGATTATGAGAATGTAATTTATGTACATAATAATTTTTAT
AATATAGATAGTATTTTAGAAGAGCTAGATATAGATAAAGTTGATGGTATAATAATGGATTTAGGGGTATCTTCTTACCA
ATTAGATGAAGCTTCAAGAGGCTTTAGTTATATGAAAGATGCACCTTTAGATATGAGAATGAATAGAGAAGAAAATCTTT
CAGCCTATAATGTAGTAAATAGTTATGAGGAAGAAGAATTGTTTAAAATATTAAAAAATTATGGAGAAGAAAAATTTTCT
AGAAAAATTGCTAGATTTATAGTAGAAAAAAGAACAGAAAATCCTATAGAAACTACAGGGGAATTAGTAGAAATAATAAG
AAAAGCTATTCCAGCTAAGTTTCAAAGAGAAGGACATCCTGCTAAAAGAACCTTTCAAGCTATAAGGATAGAAGTAAACA
AGGAACTTCAAATATTAAATAAAGCTATAGAAGACAGTGTAAATAGACTAAATAAAGATGGAAGATTAAGCATAATAACC
TTTCATTCTTTGGAGGATAGAATAGTAAAGGTGAAATTTAAAGAACTAGAAAAACCATGTACTTGCCCGCCAAGTTTCCC
AATTTGTGTCTGTGGGAAAGAGCCACAAATAAAAATAATAACAAAAAAACCAATAGAACCTTCAAAAGAAGAAAAAGAAA
TTAACTCTAGAAGTAGAAGTGCAAAACTAAGAGTATGTAGAAAAATATAA

Upstream 100 bases:

>100_bases
ATGAGTGAACTTGGAATATGATTATTTATTATATTTTAACTATTTAGATTTAATCTTAATTATAAAATAAGTGTAAATGC
ATTACATTAGGAGGATACAC

Downstream 100 bases:

>100_bases
ATATATGAGTTTAATGCTTTTAAAAATTTTATATCTAATACTTTAAAAATATAGTTATAAAACAGAGGGAGGCTGAATAA
ATTGGTAATGTTAGAAGCAA

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MEFKHISVLLEETIDSLNIKEDGVYVDCTLGGGGHSKEILKKLSHKGKLIGIDQDTSAIKAAKERLKDYENVIYVHNNFY
NIDSILEELDIDKVDGIIMDLGVSSYQLDEASRGFSYMKDAPLDMRMNREENLSAYNVVNSYEEEELFKILKNYGEEKFS
RKIARFIVEKRTENPIETTGELVEIIRKAIPAKFQREGHPAKRTFQAIRIEVNKELQILNKAIEDSVNRLNKDGRLSIIT
FHSLEDRIVKVKFKELEKPCTCPPSFPICVCGKEPQIKIITKKPIEPSKEEKEINSRSRSAKLRVCRKI

Sequences:

>Translated_309_residues
MEFKHISVLLEETIDSLNIKEDGVYVDCTLGGGGHSKEILKKLSHKGKLIGIDQDTSAIKAAKERLKDYENVIYVHNNFY
NIDSILEELDIDKVDGIIMDLGVSSYQLDEASRGFSYMKDAPLDMRMNREENLSAYNVVNSYEEEELFKILKNYGEEKFS
RKIARFIVEKRTENPIETTGELVEIIRKAIPAKFQREGHPAKRTFQAIRIEVNKELQILNKAIEDSVNRLNKDGRLSIIT
FHSLEDRIVKVKFKELEKPCTCPPSFPICVCGKEPQIKIITKKPIEPSKEEKEINSRSRSAKLRVCRKI
>Mature_309_residues
MEFKHISVLLEETIDSLNIKEDGVYVDCTLGGGGHSKEILKKLSHKGKLIGIDQDTSAIKAAKERLKDYENVIYVHNNFY
NIDSILEELDIDKVDGIIMDLGVSSYQLDEASRGFSYMKDAPLDMRMNREENLSAYNVVNSYEEEELFKILKNYGEEKFS
RKIARFIVEKRTENPIETTGELVEIIRKAIPAKFQREGHPAKRTFQAIRIEVNKELQILNKAIEDSVNRLNKDGRLSIIT
FHSLEDRIVKVKFKELEKPCTCPPSFPICVCGKEPQIKIITKKPIEPSKEEKEINSRSRSAKLRVCRKI

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=337, Percent_Identity=35.0148367952522, Blast_Score=175, Evalue=4e-44,
Organism=Homo sapiens, GI165377202, Length=188, Percent_Identity=38.2978723404255, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1786270, Length=313, Percent_Identity=44.0894568690096, Blast_Score=260, Evalue=9e-71,
Organism=Drosophila melanogaster, GI62472493, Length=329, Percent_Identity=38.2978723404255, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28571637, Length=329, Percent_Identity=38.2978723404255, Blast_Score=176, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 35507; Mature: 35507

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFKHISVLLEETIDSLNIKEDGVYVDCTLGGGGHSKEILKKLSHKGKLIGIDQDTSAIK
CCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCHHHHH
AAKERLKDYENVIYVHNNFYNIDSILEELDIDKVDGIIMDLGVSSYQLDEASRGFSYMKD
HHHHHHHHHHCEEEEECCEECHHHHHHHHCCHHHCCEEEECCCCHHCCCHHHCCCHHHCC
APLDMRMNREENLSAYNVVNSYEEEELFKILKNYGEEKFSRKIARFIVEKRTENPIETTG
CCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHH
ELVEIIRKAIPAKFQREGHPAKRTFQAIRIEVNKELQILNKAIEDSVNRLNKDGRLSIIT
HHHHHHHHHCCHHHHHCCCHHHHHHHHHHEEECHHHHHHHHHHHHHHHHCCCCCCEEEEE
FHSLEDRIVKVKFKELEKPCTCPPSFPICVCGKEPQIKIITKKPIEPSKEEKEINSRSRS
EECCCCHHEEEEHHHCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHH
AKLRVCRKI
HHHHHHHCC
>Mature Secondary Structure
MEFKHISVLLEETIDSLNIKEDGVYVDCTLGGGGHSKEILKKLSHKGKLIGIDQDTSAIK
CCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCHHHHH
AAKERLKDYENVIYVHNNFYNIDSILEELDIDKVDGIIMDLGVSSYQLDEASRGFSYMKD
HHHHHHHHHHCEEEEECCEECHHHHHHHHCCHHHCCEEEECCCCHHCCCHHHCCCHHHCC
APLDMRMNREENLSAYNVVNSYEEEELFKILKNYGEEKFSRKIARFIVEKRTENPIETTG
CCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHH
ELVEIIRKAIPAKFQREGHPAKRTFQAIRIEVNKELQILNKAIEDSVNRLNKDGRLSIIT
HHHHHHHHHCCHHHHHCCCHHHHHHHHHHEEECHHHHHHHHHHHHHHHHCCCCCCEEEEE
FHSLEDRIVKVKFKELEKPCTCPPSFPICVCGKEPQIKIITKKPIEPSKEEKEINSRSRS
EECCCCHHEEEEHHHCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHH
AKLRVCRKI
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA