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The map label for this gene is glpT [H]

Identifier: 226948349

GI number: 226948349

Start: 1282238

End: 1283575

Strand: Direct

Name: glpT [H]

Synonym: CLM_1231

Alternate gene names: 226948349

Gene position: 1282238-1283575 (Clockwise)

Preceding gene: 226948348

Following gene: 226948350

Centisome position: 30.86

GC content: 32.51

Gene sequence:

>1338_bases
ATGTTAAAGGACTTATTTAAACCGGCTTCTCACATAGAAAGAATGCCAAAGGAAAAAATTGATTCGGCTTATAGGCGGTA
TCGTATACAGGTATTTATAAGTATTTATGTAGGATATCTAACTTATTATTTTGTAAGAAGTAATTTTTCTTTGGCAAAGG
TTTACTTAATACAAGAAGGTTTTACTAAGACTCAATTAGGTTTTGTAGCTTCAGCTCTTGGTCTTGCTTATGGAGTAAGT
AAGTTTGTAATGGGAAACTTATCAGATAGATCTAATCCTAGATATTTTTTAGCAGCAGGATTAATTCTATCTGGTATTGT
AAACCTATTCTTTCCTATGACTAAAAGTATCACAGCAATGTTTGCATTAATGCTTTTAAATGGATGGTTCCAAGGTATGG
GATGGCCACCTTGTGGAAGAACTATGACCCATTGGTTTTCAGATAGAGAACGTGGAGTAAAAATGTCTATATGGAATACT
GCCCATAATGTAGGTGGAGGTTTTATTGCTACAGTAGTTTTAATTGGTGTATCTGTGTTTGGAAGTTGGAAGGGAGCTTT
TTATCTACCAGCCGTAATAGCTATTGTAGTAGGAATTTTATTTATATTATTTGCAAAGGATACACCTCAATCAGTGGGGC
TTCCACCAATAGAAGAATACAAAAATGATTATCCAGAAATTCAAGTAGAGGATAGAGAAAAAGAATTATCAGGAAAAGAA
ATATTATTTAAATATGTTTTAAATAATAAATATTTATGGTATATAGCTATAGCAAATATTTTTGTATATCTTGTTAGATA
TGGAGTTATAAATTGGGTACCTACATACTTAAAAGAAGTTAAACATTTTAATCCTAAAGATTCATCTTTAGCTTTTGCTT
TGTTTGAATATGCAGCAATACCAGGAACCATATTTGTTGGATGGTTAAGTGATAAAGTCTTTAACGGAAGACGTGCACCT
GTTGGAGTATTTTGTATGATAGGTGTAACTATAGCAACTTATGTATATTGGAAAAGTAATAGTATATTAGCAATAAATTG
TGCCCTATCTTCTATAGGAGCTTTAATATATGGACCAGTTATGTTAATAGGTGTAAGTGCCTTAGATTTAGTTCCTAAAA
AAGCAGCAGGTACGGCAGCAGGCTTTACAGGTTTATTTGGATATATGGGGGGACAAGTATTAGCAGAAGTAGCAATGGGA
GCAGTTGTTGATAAATTTAGCTGGAATGGAGGGTTTATTTTATTAATGATATCCTCTGTATTAGCTATAGTATTTTTATC
TTTTACTTGGAATACCCATGATAGATCAGAAAAAGGGCCTGATAAGGTAGCAGTTTAA

Upstream 100 bases:

>100_bases
TGTAAAAATTAAATATCAATAAGGATAGCTAATATAATATTAGCTATCCTTATTGGCGGTTAATAAATATTGACAATAAA
AGGAAAGAGGGAATGACATA

Downstream 100 bases:

>100_bases
AAATAGAATATATTTTTAAAACTTGACAAAAATAATAAATAAAGCATATAATAGATTATAAATTTTAAAGTAAAATATTT
ATATTCATTGATGAGAAGAG

Product: glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MLKDLFKPASHIERMPKEKIDSAYRRYRIQVFISIYVGYLTYYFVRSNFSLAKVYLIQEGFTKTQLGFVASALGLAYGVS
KFVMGNLSDRSNPRYFLAAGLILSGIVNLFFPMTKSITAMFALMLLNGWFQGMGWPPCGRTMTHWFSDRERGVKMSIWNT
AHNVGGGFIATVVLIGVSVFGSWKGAFYLPAVIAIVVGILFILFAKDTPQSVGLPPIEEYKNDYPEIQVEDREKELSGKE
ILFKYVLNNKYLWYIAIANIFVYLVRYGVINWVPTYLKEVKHFNPKDSSLAFALFEYAAIPGTIFVGWLSDKVFNGRRAP
VGVFCMIGVTIATYVYWKSNSILAINCALSSIGALIYGPVMLIGVSALDLVPKKAAGTAAGFTGLFGYMGGQVLAEVAMG
AVVDKFSWNGGFILLMISSVLAIVFLSFTWNTHDRSEKGPDKVAV

Sequences:

>Translated_445_residues
MLKDLFKPASHIERMPKEKIDSAYRRYRIQVFISIYVGYLTYYFVRSNFSLAKVYLIQEGFTKTQLGFVASALGLAYGVS
KFVMGNLSDRSNPRYFLAAGLILSGIVNLFFPMTKSITAMFALMLLNGWFQGMGWPPCGRTMTHWFSDRERGVKMSIWNT
AHNVGGGFIATVVLIGVSVFGSWKGAFYLPAVIAIVVGILFILFAKDTPQSVGLPPIEEYKNDYPEIQVEDREKELSGKE
ILFKYVLNNKYLWYIAIANIFVYLVRYGVINWVPTYLKEVKHFNPKDSSLAFALFEYAAIPGTIFVGWLSDKVFNGRRAP
VGVFCMIGVTIATYVYWKSNSILAINCALSSIGALIYGPVMLIGVSALDLVPKKAAGTAAGFTGLFGYMGGQVLAEVAMG
AVVDKFSWNGGFILLMISSVLAIVFLSFTWNTHDRSEKGPDKVAV
>Mature_445_residues
MLKDLFKPASHIERMPKEKIDSAYRRYRIQVFISIYVGYLTYYFVRSNFSLAKVYLIQEGFTKTQLGFVASALGLAYGVS
KFVMGNLSDRSNPRYFLAAGLILSGIVNLFFPMTKSITAMFALMLLNGWFQGMGWPPCGRTMTHWFSDRERGVKMSIWNT
AHNVGGGFIATVVLIGVSVFGSWKGAFYLPAVIAIVVGILFILFAKDTPQSVGLPPIEEYKNDYPEIQVEDREKELSGKE
ILFKYVLNNKYLWYIAIANIFVYLVRYGVINWVPTYLKEVKHFNPKDSSLAFALFEYAAIPGTIFVGWLSDKVFNGRRAP
VGVFCMIGVTIATYVYWKSNSILAINCALSSIGALIYGPVMLIGVSALDLVPKKAAGTAAGFTGLFGYMGGQVLAEVAMG
AVVDKFSWNGGFILLMISSVLAIVFLSFTWNTHDRSEKGPDKVAV

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=402, Percent_Identity=29.8507462686567, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI4503847, Length=402, Percent_Identity=29.8507462686567, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI256219483, Length=402, Percent_Identity=29.8507462686567, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI256219543, Length=424, Percent_Identity=29.0094339622642, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI256219564, Length=333, Percent_Identity=27.3273273273273, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI38093649, Length=398, Percent_Identity=27.1356783919598, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI223717983, Length=398, Percent_Identity=27.1356783919598, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI49619231, Length=406, Percent_Identity=22.9064039408867, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI46361976, Length=397, Percent_Identity=23.9294710327456, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1788573, Length=430, Percent_Identity=56.9767441860465, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI87082310, Length=433, Percent_Identity=36.7205542725173, Blast_Score=290, Evalue=9e-80,
Organism=Escherichia coli, GI2367259, Length=446, Percent_Identity=32.9596412556054, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI2367379, Length=345, Percent_Identity=24.0579710144928, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87082320, Length=358, Percent_Identity=22.9050279329609, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789515, Length=450, Percent_Identity=22.4444444444444, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789152, Length=455, Percent_Identity=22.8571428571429, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17564204, Length=380, Percent_Identity=26.5789473684211, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564202, Length=443, Percent_Identity=25.7336343115124, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI133901856, Length=480, Percent_Identity=22.5, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI133901854, Length=475, Percent_Identity=22.3157894736842, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17542316, Length=492, Percent_Identity=23.780487804878, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71991448, Length=454, Percent_Identity=20.9251101321586, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71991453, Length=454, Percent_Identity=20.9251101321586, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540458, Length=284, Percent_Identity=22.5352112676056, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24656861, Length=485, Percent_Identity=21.8556701030928, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24656866, Length=485, Percent_Identity=21.8556701030928, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45550478, Length=485, Percent_Identity=21.8556701030928, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49447; Mature: 49447

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKDLFKPASHIERMPKEKIDSAYRRYRIQVFISIYVGYLTYYFVRSNFSLAKVYLIQEG
CCHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
FTKTQLGFVASALGLAYGVSKFVMGNLSDRSNPRYFLAAGLILSGIVNLFFPMTKSITAM
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FALMLLNGWFQGMGWPPCGRTMTHWFSDRERGVKMSIWNTAHNVGGGFIATVVLIGVSVF
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHCCCHHHHHHHHHHHHHH
GSWKGAFYLPAVIAIVVGILFILFAKDTPQSVGLPPIEEYKNDYPEIQVEDREKELSGKE
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEECCCHHHCCHHH
ILFKYVLNNKYLWYIAIANIFVYLVRYGVINWVPTYLKEVKHFNPKDSSLAFALFEYAAI
HHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
PGTIFVGWLSDKVFNGRRAPVGVFCMIGVTIATYVYWKSNSILAINCALSSIGALIYGPV
CCCEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHEEECCCCEEEEEEHHHHHHHHHHHHH
MLIGVSALDLVPKKAAGTAAGFTGLFGYMGGQVLAEVAMGAVVDKFSWNGGFILLMISSV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LAIVFLSFTWNTHDRSEKGPDKVAV
HHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLKDLFKPASHIERMPKEKIDSAYRRYRIQVFISIYVGYLTYYFVRSNFSLAKVYLIQEG
CCHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
FTKTQLGFVASALGLAYGVSKFVMGNLSDRSNPRYFLAAGLILSGIVNLFFPMTKSITAM
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FALMLLNGWFQGMGWPPCGRTMTHWFSDRERGVKMSIWNTAHNVGGGFIATVVLIGVSVF
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHCCCHHHHHHHHHHHHHH
GSWKGAFYLPAVIAIVVGILFILFAKDTPQSVGLPPIEEYKNDYPEIQVEDREKELSGKE
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEECCCHHHCCHHH
ILFKYVLNNKYLWYIAIANIFVYLVRYGVINWVPTYLKEVKHFNPKDSSLAFALFEYAAI
HHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
PGTIFVGWLSDKVFNGRRAPVGVFCMIGVTIATYVYWKSNSILAINCALSSIGALIYGPV
CCCEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHEEECCCCEEEEEEHHHHHHHHHHHHH
MLIGVSALDLVPKKAAGTAAGFTGLFGYMGGQVLAEVAMGAVVDKFSWNGGFILLMISSV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LAIVFLSFTWNTHDRSEKGPDKVAV
HHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8012593; 9384377 [H]