| Definition | Clostridium botulinum A2 str. Kyoto chromosome, complete genome. |
|---|---|
| Accession | NC_012563 |
| Length | 4,155,278 |
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The map label for this gene is trxB [H]
Identifier: 226948347
GI number: 226948347
Start: 1280522
End: 1281778
Strand: Direct
Name: trxB [H]
Synonym: CLM_1229
Alternate gene names: 226948347
Gene position: 1280522-1281778 (Clockwise)
Preceding gene: 226948346
Following gene: 226948348
Centisome position: 30.82
GC content: 31.34
Gene sequence:
>1257_bases ATGCAACAATATGATGTAGTTATAATTGGTGGAGGCCCAGCAGGTCTTGCCGCTGCTATAAAAGCTAAAGAAGAAGGCGT AGACAGTATATTAATATTAGAGAGAGATAAAAGATTAGGTGGAATATTAAATCAATGTATTCATAATGGATTTGGACTTC ATACTTTTAAAGAAGAACTTACAGGACCAGAATATGCTCAAAGATTTGTAGATAAAGTAAAAGAAATGAAAATACCATAC AAATTAAATACTATGGTAATTGATATGAACAAAGATAAAATAATAACAGCAGTTAATGAGGAAGATGGATTAATAGAAGT GCAAGCTAAATCTATAGTACTAGCTATGGGTTGTAGAGAAAGATCAAGAGGAGCTATAAATATTCCAGGCACAAGATGTT CAGGGATATATTCAGCAGGAACAGCACAAAAATTTGTAAATATAGAGGGTGAAATGCCAGGAAAGGAAGTAGTTATTTTA GGGTCTGGAGATATAGGACTTATAATGGCTAGAAGAATGACTTTAGAAGGATCTAAAGTAAAGGCAGTAGTAGAACTTAT GCCTTATTCTGGAGGATTAAAAAGAAATATAGTTCAATGTTTGGATGACTTCGGTATTCCTTTAAAGCTAGCTCATACTA TAACTAAAATAGAAGGAAAAGAAAGATTAGAAGCTGTTACTATAGCAAAGGTAGATGAAAAACTAAAACCTATAAAAGGA ACAGAAGAATATATAAAATGTGATACATTACTTTTATCAGTTGGATTGCTTCCAGAAAATGATCTATCAAGAAAAGCAGA TGTTAAGTTAGGAGTAACTGGTGGTCCAGAAGTAGATGAAACAATGCAAACTAATATAGATGGAGTGTTTGCTTGTGGTA ATGTTCTTCACGTACATGATTTAGTAGACTTTGTAACAGAGGAAAGTTATAATGCAGGTAAAAATGCTGCAGATTATGTA AAGGGTAAAAAAGTAGAAGGTGAAAAAATAGAACTAGTTGCAGAAAATGGTGTAGGATATACTGTACCAAAATCAATACA CAAAAGCAATATAGAAAATACAGTAGATGTTAGATTTAGAGTAAGAAATGTGTTTAAAGATAGTTTCATATCTGTATATT TTGATGATGAAAGAGTAGTTCATAGAAAGAAAAAAGTTATAGCTCCAGGTGAGATGGAAACAGTAAAATTAACTAAAGAT ATGTTTGAAAAACATTTAGATTGCAAAAAAATTACTGTTAAAGTGGAAGGTGAATAA
Upstream 100 bases:
>100_bases AATGAAGTTACTAAGTTTGGCGGAAATTCAAAAATATTATATTAGAAAACTAATTTAAATTAATGAGGTAATTTAAAGCA AATGCATTGGAGGGCGTAGT
Downstream 100 bases:
>100_bases TTATGGCTGTAAGAGAATTAATATGTATAGGATGTCCATTGGGATGTAATCTAGAAGTAGAAATTGAAGATAAAGAAGTA AAGTCAGTTAAGGGAAATAC
Product: pyridine nucleotide-disulfide oxidoreductase
Products: NA
Alternate protein names: TRXR [H]
Number of amino acids: Translated: 418; Mature: 418
Protein sequence:
>418_residues MQQYDVVIIGGGPAGLAAAIKAKEEGVDSILILERDKRLGGILNQCIHNGFGLHTFKEELTGPEYAQRFVDKVKEMKIPY KLNTMVIDMNKDKIITAVNEEDGLIEVQAKSIVLAMGCRERSRGAINIPGTRCSGIYSAGTAQKFVNIEGEMPGKEVVIL GSGDIGLIMARRMTLEGSKVKAVVELMPYSGGLKRNIVQCLDDFGIPLKLAHTITKIEGKERLEAVTIAKVDEKLKPIKG TEEYIKCDTLLLSVGLLPENDLSRKADVKLGVTGGPEVDETMQTNIDGVFACGNVLHVHDLVDFVTEESYNAGKNAADYV KGKKVEGEKIELVAENGVGYTVPKSIHKSNIENTVDVRFRVRNVFKDSFISVYFDDERVVHRKKKVIAPGEMETVKLTKD MFEKHLDCKKITVKVEGE
Sequences:
>Translated_418_residues MQQYDVVIIGGGPAGLAAAIKAKEEGVDSILILERDKRLGGILNQCIHNGFGLHTFKEELTGPEYAQRFVDKVKEMKIPY KLNTMVIDMNKDKIITAVNEEDGLIEVQAKSIVLAMGCRERSRGAINIPGTRCSGIYSAGTAQKFVNIEGEMPGKEVVIL GSGDIGLIMARRMTLEGSKVKAVVELMPYSGGLKRNIVQCLDDFGIPLKLAHTITKIEGKERLEAVTIAKVDEKLKPIKG TEEYIKCDTLLLSVGLLPENDLSRKADVKLGVTGGPEVDETMQTNIDGVFACGNVLHVHDLVDFVTEESYNAGKNAADYV KGKKVEGEKIELVAENGVGYTVPKSIHKSNIENTVDVRFRVRNVFKDSFISVYFDDERVVHRKKKVIAPGEMETVKLTKD MFEKHLDCKKITVKVEGE >Mature_418_residues MQQYDVVIIGGGPAGLAAAIKAKEEGVDSILILERDKRLGGILNQCIHNGFGLHTFKEELTGPEYAQRFVDKVKEMKIPY KLNTMVIDMNKDKIITAVNEEDGLIEVQAKSIVLAMGCRERSRGAINIPGTRCSGIYSAGTAQKFVNIEGEMPGKEVVIL GSGDIGLIMARRMTLEGSKVKAVVELMPYSGGLKRNIVQCLDDFGIPLKLAHTITKIEGKERLEAVTIAKVDEKLKPIKG TEEYIKCDTLLLSVGLLPENDLSRKADVKLGVTGGPEVDETMQTNIDGVFACGNVLHVHDLVDFVTEESYNAGKNAADYV KGKKVEGEKIELVAENGVGYTVPKSIHKSNIENTVDVRFRVRNVFKDSFISVYFDDERVVHRKKKVIAPGEMETVKLTKD MFEKHLDCKKITVKVEGE
Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]
COG id: COG0446
COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]
Homologues:
None
Paralogues:
None
Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013027 - InterPro: IPR008255 - InterPro: IPR001327 - InterPro: IPR000103 - InterPro: IPR005982 [H]
Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]
EC number: =1.8.1.9 [H]
Molecular weight: Translated: 46039; Mature: 46039
Theoretical pI: Translated: 6.72; Mature: 6.72
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQQYDVVIIGGGPAGLAAAIKAKEEGVDSILILERDKRLGGILNQCIHNGFGLHTFKEEL CCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHC TGPEYAQRFVDKVKEMKIPYKLNTMVIDMNKDKIITAVNEEDGLIEVQAKSIVLAMGCRE CCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEECCCCCEEEEEECEEEEEECCCC RSRGAINIPGTRCSGIYSAGTAQKFVNIEGEMPGKEVVILGSGDIGLIMARRMTLEGSKV CCCCEEECCCCCCCCEECCCCCEEEEEECCCCCCCEEEEEECCCEEEEEEEEEECCCCCE KAVVELMPYSGGLKRNIVQCLDDFGIPLKLAHTITKIEGKERLEAVTIAKVDEKLKPIKG EEEEEEECCCCCHHHHHHHHHHHCCCCEEEHHHHHHCCCHHHHHEEHHHHHHHHHCCCCC TEEYIKCDTLLLSVGLLPENDLSRKADVKLGVTGGPEVDETMQTNIDGVFACGNVLHVHD CHHHHHHHHHEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHCCCCEEEECCCEEHHHH LVDFVTEESYNAGKNAADYVKGKKVEGEKIELVAENGVGYTVPKSIHKSNIENTVDVRFR HHHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCEEEEEHH VRNVFKDSFISVYFDDERVVHRKKKVIAPGEMETVKLTKDMFEKHLDCKKITVKVEGE HHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCEEEEEEEECC >Mature Secondary Structure MQQYDVVIIGGGPAGLAAAIKAKEEGVDSILILERDKRLGGILNQCIHNGFGLHTFKEEL CCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHC TGPEYAQRFVDKVKEMKIPYKLNTMVIDMNKDKIITAVNEEDGLIEVQAKSIVLAMGCRE CCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEECCCCCEEEEEECEEEEEECCCC RSRGAINIPGTRCSGIYSAGTAQKFVNIEGEMPGKEVVILGSGDIGLIMARRMTLEGSKV CCCCEEECCCCCCCCEECCCCCEEEEEECCCCCCCEEEEEECCCEEEEEEEEEECCCCCE KAVVELMPYSGGLKRNIVQCLDDFGIPLKLAHTITKIEGKERLEAVTIAKVDEKLKPIKG EEEEEEECCCCCHHHHHHHHHHHCCCCEEEHHHHHHCCCHHHHHEEHHHHHHHHHCCCCC TEEYIKCDTLLLSVGLLPENDLSRKADVKLGVTGGPEVDETMQTNIDGVFACGNVLHVHD CHHHHHHHHHEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHCCCCEEEECCCEEHHHH LVDFVTEESYNAGKNAADYVKGKKVEGEKIELVAENGVGYTVPKSIHKSNIENTVDVRFR HHHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCEEEEEHH VRNVFKDSFISVYFDDERVVHRKKKVIAPGEMETVKLTKDMFEKHLDCKKITVKVEGE HHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCEEEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11679669 [H]