Click here to switch to the map view.

The map label for this gene is yyaL [H]

Identifier: 226948333

GI number: 226948333

Start: 1262230

End: 1264272

Strand: Direct

Name: yyaL [H]

Synonym: CLM_1215

Alternate gene names: 226948333

Gene position: 1262230-1264272 (Clockwise)

Preceding gene: 226948332

Following gene: 226948334

Centisome position: 30.38

GC content: 27.9

Gene sequence:

>2043_bases
ATGAACCTAACAAGTACGAATAGATTAATAAATGAGAAATCCCCTTATTTACTTCAACATGCTCATAATCCAGTAGATTG
GTATCCTTGGGGGGAAGAAGCTTTTGAAAAAGCAAAGATAGAGGATAAGCCTGTATTTTTAAGTATAGGTTATTCTACCT
GTCATTGGTGCCATGTTATGGAAAGAGAGTCCTTTGAGGATGAGGAAGTTGCGGAAGTTTTAAATAAGAACTTTATTTCT
ATAAAGGTAGATAGAGAAGAAAGACCAGATATAGATAGTATATATATGAATTTTTGTCAGGCTTATACTGGTAGTGGTGG
ATGGCCTTTAACTATAATTATGACTCCAGATAAAAAGCCCTTTTTTGCAGGTACTTATTTCCCAAAATGGGGAAAGTACA
ATGTACCTGGAATTATGGATATTTTAAGATCTATAAGTAATCTTTGGAGAGAAGATAAAAATAAAATATTAGAATCCAGT
AATAGAATATTAGAGCAAATAGAAAGATTTCAAGATAATCATAGAGAAGGTGAACTTGAAGAATATATTATTGAAGAAGC
TGCCAAAACTCTACTAGATAATTTTGATAATCAATATGGTGGCTTTGGTACATATCCTAAATTTCCTACAGCTCATTATA
TATTATTCTTATTAAGATACTATTATTTTAAAAAGGATAAAAAAATATTAGATATTGTAAATAAGACTTTAACTAGTATG
TATAAAGGTGGAATATTTGATCATATAGGTTTTGGATTTTCAAGATATTCTACAGATAATAAGTGGCTTGTACCTCACTT
TGAAAAGATGCTTTATGATAATGCACTCTTATCTATGGCTTATACAGAAGCTTATGAAGCTACAAAGAATCCATTATTTA
AAGATATAACAGAAAAAGTATTAAACTATGTAAAAAAATCCATGACTTCTGAAAAGGGAGGGTTTTATTCTGCGGAGGAT
GCAGATTCTGAAGGGGTAGAAGGGAAATTTTATTTATGGACTAAAGAAGAAATAATGGATATTTTAGGTGAGGAAGAAGG
GGAATTTTACTGTAAGATTTATGATATAACATCTAAAGGAAATTTTGAGAATAAAAATATAGCTAATCTTATAAATACAG
ACTTAAAGATTGTAGATAATAATAAAGATAAATTAGAAAAAATTAGAGAAAAATTATTTGAATACAGAGAAAAAAGAATA
CATCCTTATAAAGATGATAAAATACTAACCTCATGGAATGCTTTAATGATAGTAGCTTTTTCTAAGGCTGGGAGAAGTCT
AAAAAATGATAATTATATAGAGATAGCAAAAAAATCAGCAAATTTTATAATAGAAAACCTAATGGATGAAAAAGGTACAT
TATATGCAAGAATTAGAGAGGGAGAAAGAGGTAATGAAGGGTTTATAGATGATTACGCTTTCTTTTTATGGGCACTTATA
GAATTATATGAAGCAAGTTTTGATATTTATTATTTAGAAAAATCTATAGAAGTTGCTAATAGTATGATAGATTTATTTTG
GCATAAAGAGGATGGTGGATTTTATCTATACAGTAAAAATAGTGAAAAACTTTTAGTAAGACCAAAGGAAATCTATGATG
GGGCTACGCCATCAGGAAATGCTGTAGCATCTTTAACATTGAATTTACTTTACTATATTACAGGAGAGGATAGATATAAA
GATTTGGTGGATAAGCAATTTAAGTTTTTTGCAACAAATATAAAAAGTGGACCAATGTATCACTTATTTTCTGTAATAGC
TTATATGTATAATATATCACCTGTAAAGGAAATAACATTAGCTTATAATGAAAAAGATGAAGATTTCTATAAGTTTATAA
ATGAACTAAATAATAGATATATACCTTTTTCAATAGTAACCTTAAATGATAAAAGTAATGAAATAGAGAAAATAAATAAA
AATATTAAAGATAAAATTGCTATAAAAGATAAAGCTACAGTTTATATATGCCAAAATTACGCCTGCAGAGAACCTATAAC
AGATTTAGAAGAATTTAAATTAGTATTATCTACTGATTCTTAG

Upstream 100 bases:

>100_bases
TCATCCATTCTTTTTTTGTTGCTTTTTTTATTTTAAGGGGAGTTAAAGAAATTTTACTGGGTATACTAATTTTATTAATA
AATTTTAAGAAGGTGTTTTT

Downstream 100 bases:

>100_bases
GGATAGTAAAGAAACATTTACAGAGTATATATTTGAATCATTGAGGTATATGGTTATGATATAAATAAATATAAAAAACA
TACGGGAAGTTATGGTAGAA

Product: hypothetical protein

Products: ADP; dTDP

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MNLTSTNRLINEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVMERESFEDEEVAEVLNKNFIS
IKVDREERPDIDSIYMNFCQAYTGSGGWPLTIIMTPDKKPFFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESS
NRILEQIERFQDNHREGELEEYIIEEAAKTLLDNFDNQYGGFGTYPKFPTAHYILFLLRYYYFKKDKKILDIVNKTLTSM
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKVLNYVKKSMTSEKGGFYSAED
ADSEGVEGKFYLWTKEEIMDILGEEEGEFYCKIYDITSKGNFENKNIANLINTDLKIVDNNKDKLEKIREKLFEYREKRI
HPYKDDKILTSWNALMIVAFSKAGRSLKNDNYIEIAKKSANFIIENLMDEKGTLYARIREGERGNEGFIDDYAFFLWALI
ELYEASFDIYYLEKSIEVANSMIDLFWHKEDGGFYLYSKNSEKLLVRPKEIYDGATPSGNAVASLTLNLLYYITGEDRYK
DLVDKQFKFFATNIKSGPMYHLFSVIAYMYNISPVKEITLAYNEKDEDFYKFINELNNRYIPFSIVTLNDKSNEIEKINK
NIKDKIAIKDKATVYICQNYACREPITDLEEFKLVLSTDS

Sequences:

>Translated_680_residues
MNLTSTNRLINEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVMERESFEDEEVAEVLNKNFIS
IKVDREERPDIDSIYMNFCQAYTGSGGWPLTIIMTPDKKPFFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESS
NRILEQIERFQDNHREGELEEYIIEEAAKTLLDNFDNQYGGFGTYPKFPTAHYILFLLRYYYFKKDKKILDIVNKTLTSM
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKVLNYVKKSMTSEKGGFYSAED
ADSEGVEGKFYLWTKEEIMDILGEEEGEFYCKIYDITSKGNFENKNIANLINTDLKIVDNNKDKLEKIREKLFEYREKRI
HPYKDDKILTSWNALMIVAFSKAGRSLKNDNYIEIAKKSANFIIENLMDEKGTLYARIREGERGNEGFIDDYAFFLWALI
ELYEASFDIYYLEKSIEVANSMIDLFWHKEDGGFYLYSKNSEKLLVRPKEIYDGATPSGNAVASLTLNLLYYITGEDRYK
DLVDKQFKFFATNIKSGPMYHLFSVIAYMYNISPVKEITLAYNEKDEDFYKFINELNNRYIPFSIVTLNDKSNEIEKINK
NIKDKIAIKDKATVYICQNYACREPITDLEEFKLVLSTDS
>Mature_680_residues
MNLTSTNRLINEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVMERESFEDEEVAEVLNKNFIS
IKVDREERPDIDSIYMNFCQAYTGSGGWPLTIIMTPDKKPFFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESS
NRILEQIERFQDNHREGELEEYIIEEAAKTLLDNFDNQYGGFGTYPKFPTAHYILFLLRYYYFKKDKKILDIVNKTLTSM
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKVLNYVKKSMTSEKGGFYSAED
ADSEGVEGKFYLWTKEEIMDILGEEEGEFYCKIYDITSKGNFENKNIANLINTDLKIVDNNKDKLEKIREKLFEYREKRI
HPYKDDKILTSWNALMIVAFSKAGRSLKNDNYIEIAKKSANFIIENLMDEKGTLYARIREGERGNEGFIDDYAFFLWALI
ELYEASFDIYYLEKSIEVANSMIDLFWHKEDGGFYLYSKNSEKLLVRPKEIYDGATPSGNAVASLTLNLLYYITGEDRYK
DLVDKQFKFFATNIKSGPMYHLFSVIAYMYNISPVKEITLAYNEKDEDFYKFINELNNRYIPFSIVTLNDKSNEIEKINK
NIKDKIAIKDKATVYICQNYACREPITDLEEFKLVLSTDS

Specific function: Unknown

COG id: COG1331

COG function: function code O; Highly conserved protein containing a thioredoxin domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To C.elegans B0495.5 [H]

Homologues:

Organism=Homo sapiens, GI31542723, Length=723, Percent_Identity=35.9612724757953, Blast_Score=486, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI25147430, Length=723, Percent_Identity=35.6846473029046, Blast_Score=427, Evalue=1e-120,
Organism=Drosophila melanogaster, GI20129985, Length=724, Percent_Identity=37.4309392265193, Blast_Score=474, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008928
- InterPro:   IPR012341
- InterPro:   IPR010819
- InterPro:   IPR004879
- InterPro:   IPR005198
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03190 DUF255; PF07221 GlcNAc_2-epim; PF03663 Glyco_hydro_76 [H]

EC number: 2.7.4.9

Molecular weight: Translated: 79686; Mature: 79686

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTSTNRLINEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVM
CCCCCCHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHH
ERESFEDEEVAEVLNKNFISIKVDREERPDIDSIYMNFCQAYTGSGGWPLTIIMTPDKKP
HHCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
FFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESSNRILEQIERFQDNHREGELE
CEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EYIIEEAAKTLLDNFDNQYGGFGTYPKFPTAHYILFLLRYYYFKKDKKILDIVNKTLTSM
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKV
HCCCCHHHHCCCHHEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LNYVKKSMTSEKGGFYSAEDADSEGVEGKFYLWTKEEIMDILGEEEGEFYCKIYDITSKG
HHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEEEEECCC
NFENKNIANLINTDLKIVDNNKDKLEKIREKLFEYREKRIHPYKDDKILTSWNALMIVAF
CCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEEEE
SKAGRSLKNDNYIEIAKKSANFIIENLMDEKGTLYARIREGERGNEGFIDDYAFFLWALI
HHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
ELYEASFDIYYLEKSIEVANSMIDLFWHKEDGGFYLYSKNSEKLLVRPKEIYDGATPSGN
HHHHCCCEEEEEHHHHHHHHHHHHHEEEECCCCEEEEECCCCEEEECCHHHHCCCCCCCC
AVASLTLNLLYYITGEDRYKDLVDKQFKFFATNIKSGPMYHLFSVIAYMYNISPVKEITL
HHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHEEE
AYNEKDEDFYKFINELNNRYIPFSIVTLNDKSNEIEKINKNIKDKIAIKDKATVYICQNY
EECCCCHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHCCHHHHEEECCCCEEEEECCC
ACREPITDLEEFKLVLSTDS
CCCCCCCCHHHEEEEEECCC
>Mature Secondary Structure
MNLTSTNRLINEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVM
CCCCCCHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHH
ERESFEDEEVAEVLNKNFISIKVDREERPDIDSIYMNFCQAYTGSGGWPLTIIMTPDKKP
HHCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
FFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESSNRILEQIERFQDNHREGELE
CEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EYIIEEAAKTLLDNFDNQYGGFGTYPKFPTAHYILFLLRYYYFKKDKKILDIVNKTLTSM
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKV
HCCCCHHHHCCCHHEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LNYVKKSMTSEKGGFYSAEDADSEGVEGKFYLWTKEEIMDILGEEEGEFYCKIYDITSKG
HHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEEEEECCC
NFENKNIANLINTDLKIVDNNKDKLEKIREKLFEYREKRIHPYKDDKILTSWNALMIVAF
CCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEEEE
SKAGRSLKNDNYIEIAKKSANFIIENLMDEKGTLYARIREGERGNEGFIDDYAFFLWALI
HHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
ELYEASFDIYYLEKSIEVANSMIDLFWHKEDGGFYLYSKNSEKLLVRPKEIYDGATPSGN
HHHHCCCEEEEEHHHHHHHHHHHHHEEEECCCCEEEEECCCCEEEECCHHHHCCCCCCCC
AVASLTLNLLYYITGEDRYKDLVDKQFKFFATNIKSGPMYHLFSVIAYMYNISPVKEITL
HHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHEEE
AYNEKDEDFYKFINELNNRYIPFSIVTLNDKSNEIEKINKNIKDKIAIKDKATVYICQNY
EECCCCHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHCCHHHHEEECCCCEEEEECCC
ACREPITDLEEFKLVLSTDS
CCCCCCCCHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dTMP

Specific reaction: ATP + dTMP = ADP + dTDP

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]