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The map label for this gene is resE [H]

Identifier: 226948312

GI number: 226948312

Start: 1233294

End: 1234649

Strand: Direct

Name: resE [H]

Synonym: CLM_1192

Alternate gene names: 226948312

Gene position: 1233294-1234649 (Clockwise)

Preceding gene: 226948311

Following gene: 226948313

Centisome position: 29.68

GC content: 28.02

Gene sequence:

>1356_bases
GTGCATACAATAAGAAAAAGATTAAGTATTTTATTTGTTATTTGCTCAGTAGCAGGAATATTGCTTGTTACATTGTTTGT
AAATGCAACTATAAATAACAAATTTGATGCATATATAGTGGATGTCCAAGATAAAAGATATCAAAGAATAGTATCTTACT
TTGAAGAAGTATATAAAGCACAAGGAAAGTGGACTAAAAATTCTGGTGTTGAGTTGATGCATGAAGCTCATATGGGAAAT
TATTGTTTAACACTTCTAGATATTAATAAAAAAACTATATGGGGTATGAACCCAAATGATATAAGATTAAATACAATGCC
TGTAAAGGATAGAGGTGTTTATAATACTAAGACTTTTGAAATTAAATCAGAAGGTAAAGTAGTTGGATATGTGGGGATTG
GACAGTATTCCTCTTTACTATTATCTGAAGAAGATATAAGTTTTAAAACATCTATAAATAAAAGTATTGTTGCTAGTGGA
ATTCTAACTCTTGTTATTATAATTACCATAAGTCTTTACTTTTCCAAACAATTCTCAATTCCAATTAAGGAGGTTGCTAA
TTTGTCTGTAAATTTATCAAAAGGAGATTTTGATGCGAAATCAAGCGTTGAAAGTAATATTGAAGAACTAGAGAATTTAA
GAAAAAGTGTTAATATATTAGCTGAAAAATTAAAGCATCAAGATTCTATAAGAAGAAGATTAGTTTCTGACATATCCCAT
GAGATCAGAACTCAATTAAATGTATTGCAAAATAACCTAGAGGCAATGATAGATGGAGTTTTACCTGTTACAGAAGAAAG
ATTAAATTGTCTGAATGAAGAAGTAGTTAGATTTGGTAGATTATTAAATAACTTAAATGTATTAAAAGAGTTTGAATCTG
AGAGTATTAAGCTTAATTTCCAAAAAATATTTTTAGATGAATTAGTTGCAGATATATGTAGTGATTTTTATGCAATAGCG
GAAAACAAGAATATTAAACTGCAATACCATATAGAAAATCATGAGGATTATAGTATAACTGGAGATAGAGATAGATTAAA
ACAAGTATTTATAAATTTACTTTCTAATGCTCTTAAATTTACAGAAGATGGCGGAGAGGTACTAATTAAAATATATAAAA
GTGATAAAAACATTGTTGTAGAAGTTAAGGATAATGGTGTAGGAATTAAAAAGGAAGATTTGCCTTTTATATTTGAGAGA
CTTTATAGGGGAGATAAGAGTAGACACCAATTTAAAGGGAATGGTATAGGGTTAACTATTGTGAAAAATATATTGCAGCT
CCATTATGCAAGTATAGATCTTGAAAGTGAAGAAGGTGAAGGAACTACTTTTAAGGTCTATTTTCATAGAATGTAA

Upstream 100 bases:

>100_bases
TATAAAGAATATTCGTAAAAAGATAGAAGAAGATACTAAGAATCCTAAATATATTGTTACAGTTATGAAAGTAGGTTATA
AATTTGGTGGTGAAAATTAA

Downstream 100 bases:

>100_bases
ATAACTAATAAAAGTACAAATAAATTTTAGAAATATTATGGAGAAATGAGAGATCCTTAAATTATAAAGTATTATTCAAA
AACACGTTTGGGGGAAGTAT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKAQGKWTKNSGVELMHEAHMGN
YCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFEIKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASG
ILTLVIIITISLYFSKQFSIPIKEVANLSVNLSKGDFDAKSSVESNIEELENLRKSVNILAEKLKHQDSIRRRLVSDISH
EIRTQLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNFQKIFLDELVADICSDFYAIA
ENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKFTEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFER
LYRGDKSRHQFKGNGIGLTIVKNILQLHYASIDLESEEGEGTTFKVYFHRM

Sequences:

>Translated_451_residues
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKAQGKWTKNSGVELMHEAHMGN
YCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFEIKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASG
ILTLVIIITISLYFSKQFSIPIKEVANLSVNLSKGDFDAKSSVESNIEELENLRKSVNILAEKLKHQDSIRRRLVSDISH
EIRTQLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNFQKIFLDELVADICSDFYAIA
ENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKFTEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFER
LYRGDKSRHQFKGNGIGLTIVKNILQLHYASIDLESEEGEGTTFKVYFHRM
>Mature_451_residues
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKAQGKWTKNSGVELMHEAHMGN
YCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFEIKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASG
ILTLVIIITISLYFSKQFSIPIKEVANLSVNLSKGDFDAKSSVESNIEELENLRKSVNILAEKLKHQDSIRRRLVSDISH
EIRTQLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNFQKIFLDELVADICSDFYAIA
ENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKFTEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFER
LYRGDKSRHQFKGNGIGLTIVKNILQLHYASIDLESEEGEGTTFKVYFHRM

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=255, Percent_Identity=34.5098039215686, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786783, Length=296, Percent_Identity=27.7027027027027, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=31.390134529148, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=26.6949152542373, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=28.2157676348548, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788713, Length=251, Percent_Identity=29.8804780876494, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789149, Length=264, Percent_Identity=25.3787878787879, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1790346, Length=295, Percent_Identity=24.7457627118644, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1789403, Length=313, Percent_Identity=25.5591054313099, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=291, Percent_Identity=22.680412371134, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=26.1802575107296, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790551, Length=299, Percent_Identity=25.752508361204, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1787894, Length=256, Percent_Identity=27.734375, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=233, Percent_Identity=26.1802575107296, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790861, Length=431, Percent_Identity=22.2737819025522, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788549, Length=215, Percent_Identity=25.1162790697674, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081816, Length=124, Percent_Identity=32.258064516129, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788279, Length=252, Percent_Identity=23.4126984126984, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51610; Mature: 51610

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
QGKWTKNSGVELMHEAHMGNYCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFE
CCCCCCCCCHHHHHHHCCCCEEEEEEECCCCEEECCCCCCEEEEEECCCCCCCCCCEEEE
IKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASGILTLVIIITISLYFSKQFSI
EECCCCEEEEEECCCHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PIKEVANLSVNLSKGDFDAKSSVESNIEELENLRKSVNILAEKLKHQDSIRRRLVSDISH
CHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIRTQLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNF
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEH
QKIFLDELVADICSDFYAIAENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKF
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHC
TEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFERLYRGDKSRHQFKGNGIGLTI
CCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCEEHHH
VKNILQLHYASIDLESEEGEGTTFKVYFHRM
HHHHHHHHHHHEEEECCCCCCCEEEEEEECC
>Mature Secondary Structure
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
QGKWTKNSGVELMHEAHMGNYCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFE
CCCCCCCCCHHHHHHHCCCCEEEEEEECCCCEEECCCCCCEEEEEECCCCCCCCCCEEEE
IKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASGILTLVIIITISLYFSKQFSI
EECCCCEEEEEECCCHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PIKEVANLSVNLSKGDFDAKSSVESNIEELENLRKSVNILAEKLKHQDSIRRRLVSDISH
CHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIRTQLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNF
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEH
QKIFLDELVADICSDFYAIAENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKF
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHC
TEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFERLYRGDKSRHQFKGNGIGLTI
CCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCEEHHH
VKNILQLHYASIDLESEEGEGTTFKVYFHRM
HHHHHHHHHHHEEEECCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]