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The map label for this gene is nsr [H]

Identifier: 226948300

GI number: 226948300

Start: 1223037

End: 1223726

Strand: Direct

Name: nsr [H]

Synonym: CLM_1180

Alternate gene names: 226948300

Gene position: 1223037-1223726 (Clockwise)

Preceding gene: 226948298

Following gene: 226948302

Centisome position: 29.43

GC content: 24.35

Gene sequence:

>690_bases
ATGAAAAAAATTTTGAATAAAGACCTTTTAGACCATTATATTGATAAGCATAATATAGAAAGAATATTTGACAAGGATAT
ATTAAAATATGCACAACTTCATTTTTATGAAAAAGAGGAATATATATTAAAAGCAGAGTCTAATCTTGAATACTATTATT
TGATTGTAGATGGGAAAATCAAAATTTCTTATCCCTTTGAAAATGGTAAATCAATTCTTTTAAAGTTTTATAAAGACTTT
AATACTATAGGAGATTTAGAGTTTTTAAAAAACATTCCAATACTCTGCGACGTTGACGCAGTAGGAGATACTTATTTGAT
AGCAATACCTTCAGGTATACTTAGAAAAAAGTATTTAGATAATATAAAGTTTTTACACCATTTAATAGACTCTTTAAGCG
AAAAACTTTATGCAACAATTAATAATAGCTCATATAATTTTGTATATCCGCTCATAAATAGATTATCTAGCTATCTAGTT
GAACATATAGAAGACAAAAACTATGTAATTTTAAATTCATCATTCTTAGAAATTGCTCAATTCCTCGGAACAACTTATAG
GCATTTAAATAGAACCTTTAAAGAGCTTGAATCAAAATCAATTATAAAATGTGAGAATAAAACAATATATATATTAGATG
AAAATAGACTTAGAGACCTATCTAAAAACTTTTATATAAAATCTCTATAA

Upstream 100 bases:

>100_bases
TATATAAATTACTCCTATGTTTTGGTTTACAATAGGTTATAAATAAATTACAATAATTATATAAATTTTAATATGACATA
TGTCATGTTATGGAGGACTT

Downstream 100 bases:

>100_bases
TGTTAGGATATTATAATAAATATAATTAATAAAATAGGACCCACCATAAAAAAGTAAGTCCTTGTTACGTCCCTTAAGAA
TATTGCTTTTGTTCTAATAT

Product: cyclic nucleotide-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKKILNKDLLDHYIDKHNIERIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKIKISYPFENGKSILLKFYKDF
NTIGDLEFLKNIPILCDVDAVGDTYLIAIPSGILRKKYLDNIKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLV
EHIEDKNYVILNSSFLEIAQFLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRDLSKNFYIKSL

Sequences:

>Translated_229_residues
MKKILNKDLLDHYIDKHNIERIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKIKISYPFENGKSILLKFYKDF
NTIGDLEFLKNIPILCDVDAVGDTYLIAIPSGILRKKYLDNIKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLV
EHIEDKNYVILNSSFLEIAQFLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRDLSKNFYIKSL
>Mature_229_residues
MKKILNKDLLDHYIDKHNIERIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKIKISYPFENGKSILLKFYKDF
NTIGDLEFLKNIPILCDVDAVGDTYLIAIPSGILRKKYLDNIKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLV
EHIEDKNYVILNSSFLEIAQFLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRDLSKNFYIKSL

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=168, Percent_Identity=25, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 27226; Mature: 27226

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILNKDLLDHYIDKHNIERIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEECEE
KISYPFENGKSILLKFYKDFNTIGDLEFLKNIPILCDVDAVGDTYLIAIPSGILRKKYLD
EEEECCCCCHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCEEEEEECCHHHHHHHHH
NIKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLVEHIEDKNYVILNSSFLEIAQ
HHHHHHHHHHHHHHHEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHH
FLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRDLSKNFYIKSL
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECHHHHHHHHCCEEECC
>Mature Secondary Structure
MKKILNKDLLDHYIDKHNIERIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEECEE
KISYPFENGKSILLKFYKDFNTIGDLEFLKNIPILCDVDAVGDTYLIAIPSGILRKKYLD
EEEECCCCCHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCEEEEEECCHHHHHHHHH
NIKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLVEHIEDKNYVILNSSFLEIAQ
HHHHHHHHHHHHHHHEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHH
FLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRDLSKNFYIKSL
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECHHHHHHHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]