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The map label for this gene is etfA [H]

Identifier: 226948283

GI number: 226948283

Start: 1206465

End: 1207667

Strand: Direct

Name: etfA [H]

Synonym: CLM_1163

Alternate gene names: 226948283

Gene position: 1206465-1207667 (Clockwise)

Preceding gene: 226948282

Following gene: 226948284

Centisome position: 29.03

GC content: 32.34

Gene sequence:

>1203_bases
ATGGGAAAATTAGTAGTAAATGAAGAAAAATTAACTCCTTCAATTATAGGGGAATTAGTTAAAATATGTCCTTTTGGAGC
ACTAGGAGAAAACAGCGGAAAAATAGAAATTTCAGCAGCCTGTAAAATGTGTAAGCTATGTGTTAAAAGAGGGCCAGCTG
GTGTTATGGAATTTGTAGAAGAAGAAAAATCACATATAGATAAGAGTATTTGGAAAGGCATAGCTGTATATGTAGATCAT
GTAGATGGAGATATTCATCCAGTAACTTACGAGCTTATAGGCAAAGCAAGAGAATTAGCGAATAAAATCAATCACCCAGT
ATATGCAGTATTTATTGGCCATGATATAAAGGAAAAAGCAGAAGAAATTCTTCACTATGGAGTAGATGAAGTATTTGTAT
ATGATAATGAAGAATTGAAAGATTTTAGAATAGAACCATACACTAAAGCTATGGAAGATTTCATAAGCAAAAATAAACCA
TCTACATTATTAGTAGGTGCAACAACAATAGGAAGATCTCTTGCACCAAGAGTGGCAGCTAGATTTAGAACAGGACTTAC
AGCAGATTGTACAATATTAGATATAAAGGAAAATACAGATTTAGTACAAATAAGACCAGCCTTTGGCGGAAATATAATGG
CACAAATAATAAATCCTAATAATAGACCTCAACTTGCAACAGTAAGATATAAGGTTATGGATGCACCAGAGCGAAATGAA
GAAAAAAGTGGAAAAGTAACTCTTTGTAGCATAGACAAAAGTCAGTTAGATTCACAAATAAAAGTATTAAAGGTAACAAA
GAAACAAGTAGAAGAAAGCATATCAGATGCGGATATAATAATTGCAGTTGGAAGAGGTCTTAAAAAAGAAAAAGATTTAG
ATATGATAAATGAACTAGCAGAATTAATAGGTGCTCAAATAGCTACAACAAGACCATTAATAGAAGCAGGATGGACAGAT
GCAAAACGTCAAATAGGTTTGAGTGGAAGGACAGTAAAGCCTAAACTTATAATTACTTGTGGTATATCAGGCGCTGTACA
ATTTACAGCAGGAATGAATAATGCAGAGTGTATAGTAGCTATAAATAAAGATCCGAAGGCATCTATATTTAATGTAGCTC
ATTATGGAATAATAGGAGACATTTATGAGGTAATACCAACACTTATAAATAATATAAAAGAAGGTAAAGGATTAACTGTA
TAA

Upstream 100 bases:

>100_bases
TGGACAGGGAGCGGAGAAGAATTAGGAAATAAGTTAACAGCAAAACTTAAAGAATTGAAATTTGTATAAAATAAAGTAAT
ACTAATGGGAGGCTTTTAAT

Downstream 100 bases:

>100_bases
TTGCTAGAGTATTTAAGGACCAATTAACTAACTGATAATTCAATTTTGGAGGTAATTATTATGGAATATAAAAAATTAGA
TGTTAAAGATATAGAGTTTT

Product: electron transfer flavoprotein subunit alpha/FixB family protein

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MGKLVVNEEKLTPSIIGELVKICPFGALGENSGKIEISAACKMCKLCVKRGPAGVMEFVEEEKSHIDKSIWKGIAVYVDH
VDGDIHPVTYELIGKARELANKINHPVYAVFIGHDIKEKAEEILHYGVDEVFVYDNEELKDFRIEPYTKAMEDFISKNKP
STLLVGATTIGRSLAPRVAARFRTGLTADCTILDIKENTDLVQIRPAFGGNIMAQIINPNNRPQLATVRYKVMDAPERNE
EKSGKVTLCSIDKSQLDSQIKVLKVTKKQVEESISDADIIIAVGRGLKKEKDLDMINELAELIGAQIATTRPLIEAGWTD
AKRQIGLSGRTVKPKLIITCGISGAVQFTAGMNNAECIVAINKDPKASIFNVAHYGIIGDIYEVIPTLINNIKEGKGLTV

Sequences:

>Translated_400_residues
MGKLVVNEEKLTPSIIGELVKICPFGALGENSGKIEISAACKMCKLCVKRGPAGVMEFVEEEKSHIDKSIWKGIAVYVDH
VDGDIHPVTYELIGKARELANKINHPVYAVFIGHDIKEKAEEILHYGVDEVFVYDNEELKDFRIEPYTKAMEDFISKNKP
STLLVGATTIGRSLAPRVAARFRTGLTADCTILDIKENTDLVQIRPAFGGNIMAQIINPNNRPQLATVRYKVMDAPERNE
EKSGKVTLCSIDKSQLDSQIKVLKVTKKQVEESISDADIIIAVGRGLKKEKDLDMINELAELIGAQIATTRPLIEAGWTD
AKRQIGLSGRTVKPKLIITCGISGAVQFTAGMNNAECIVAINKDPKASIFNVAHYGIIGDIYEVIPTLINNIKEGKGLTV
>Mature_399_residues
GKLVVNEEKLTPSIIGELVKICPFGALGENSGKIEISAACKMCKLCVKRGPAGVMEFVEEEKSHIDKSIWKGIAVYVDHV
DGDIHPVTYELIGKARELANKINHPVYAVFIGHDIKEKAEEILHYGVDEVFVYDNEELKDFRIEPYTKAMEDFISKNKPS
TLLVGATTIGRSLAPRVAARFRTGLTADCTILDIKENTDLVQIRPAFGGNIMAQIINPNNRPQLATVRYKVMDAPERNEE
KSGKVTLCSIDKSQLDSQIKVLKVTKKQVEESISDADIIIAVGRGLKKEKDLDMINELAELIGAQIATTRPLIEAGWTDA
KRQIGLSGRTVKPKLIITCGISGAVQFTAGMNNAECIVAINKDPKASIFNVAHYGIIGDIYEVIPTLINNIKEGKGLTV

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=330, Percent_Identity=28.1818181818182, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI189181759, Length=273, Percent_Identity=30.7692307692308, Blast_Score=125, Evalue=7e-29,
Organism=Escherichia coli, GI1787990, Length=318, Percent_Identity=32.7044025157233, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1786226, Length=308, Percent_Identity=27.2727272727273, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082157, Length=261, Percent_Identity=26.8199233716475, Blast_Score=92, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17506929, Length=318, Percent_Identity=28.9308176100629, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6325261, Length=304, Percent_Identity=29.9342105263158, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136898, Length=340, Percent_Identity=30, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24652801, Length=340, Percent_Identity=30, Blast_Score=135, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 43883; Mature: 43752

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLVVNEEKLTPSIIGELVKICPFGALGENSGKIEISAACKMCKLCVKRGPAGVMEFVE
CCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHH
EEKSHIDKSIWKGIAVYVDHVDGDIHPVTYELIGKARELANKINHPVYAVFIGHDIKEKA
HHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHH
EEILHYGVDEVFVYDNEELKDFRIEPYTKAMEDFISKNKPSTLLVGATTIGRSLAPRVAA
HHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHH
RFRTGLTADCTILDIKENTDLVQIRPAFGGNIMAQIINPNNRPQLATVRYKVMDAPERNE
HHHCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCC
EKSGKVTLCSIDKSQLDSQIKVLKVTKKQVEESISDADIIIAVGRGLKKEKDLDMINELA
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHH
ELIGAQIATTRPLIEAGWTDAKRQIGLSGRTVKPKLIITCGISGAVQFTAGMNNAECIVA
HHHCCHHHCCCCHHHCCCCCHHHHCCCCCCEECCEEEEEECCCCEEEEECCCCCCEEEEE
INKDPKASIFNVAHYGIIGDIYEVIPTLINNIKEGKGLTV
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GKLVVNEEKLTPSIIGELVKICPFGALGENSGKIEISAACKMCKLCVKRGPAGVMEFVE
CCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHH
EEKSHIDKSIWKGIAVYVDHVDGDIHPVTYELIGKARELANKINHPVYAVFIGHDIKEKA
HHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHH
EEILHYGVDEVFVYDNEELKDFRIEPYTKAMEDFISKNKPSTLLVGATTIGRSLAPRVAA
HHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHH
RFRTGLTADCTILDIKENTDLVQIRPAFGGNIMAQIINPNNRPQLATVRYKVMDAPERNE
HHHCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCC
EKSGKVTLCSIDKSQLDSQIKVLKVTKKQVEESISDADIIIAVGRGLKKEKDLDMINELA
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHH
ELIGAQIATTRPLIEAGWTDAKRQIGLSGRTVKPKLIITCGISGAVQFTAGMNNAECIVA
HHHCCHHHCCCCHHHCCCCCHHHHCCCCCCEECCEEEEEECCCCEEEEECCCCCCEEEEE
INKDPKASIFNVAHYGIIGDIYEVIPTLINNIKEGKGLTV
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9694853 [H]