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The map label for this gene is thrC [H]

Identifier: 226948249

GI number: 226948249

Start: 1165793

End: 1166911

Strand: Direct

Name: thrC [H]

Synonym: CLM_1127

Alternate gene names: 226948249

Gene position: 1165793-1166911 (Clockwise)

Preceding gene: 226948247

Following gene: 226948250

Centisome position: 28.06

GC content: 32.08

Gene sequence:

>1119_bases
ATGATTGAGAGAAATAAATCCATAAAAAATTTGTATTGTATTAGGTGCAATAAAAAGTATGGAATATCAGATTATTTTAG
GGGGTGTGAAAAATGTTTAAATGATGGACTACCAGCAAGTGTAACATTTCATTATGAAGTAGGGGAAAGTGTTAATAATA
TAAATGAGGTGTTTCCCTATTCAATGCAATCAATGTTAGGTGAAGGTAATACTCCAATAATTAGTCATAAAAAAATCAGT
GATATATATGGAATTGAAAGTTTTTATTTGAAAAACGAATTTCAAAATCCAACAGGATCACATAAGGATAGAATGAGTCC
TTATATTGTTGCTAGGGCAATAGAGATGAAAAGAAAAGGGGTGGTAGTAGCCTCAAGTGGAAATGCAGGTATTTCTATAG
CATCTTATGCTAGTTATAAAGGGGTGAAATCTATAGTAGTTACTACTAAGGGAATAAACCCAGTTTATAAGAGAGCTATT
GAAGCTACTGGTGCACAAATTATAATTACCGAAACATCAGATGAAAGATGGAACATAGTTAAGAAATTAGTAGATATAGA
AGGGTGGTACCCAGCGACAAACTATATAAATCCACCTGTTGGCAGCAATCCATTTGGAGTACAAGGCTACAAAAAAATAG
CCTTTGAGATATATGAATTTTTTAATGAAAAACTACCCACTCATATATTAATCCCGGTTTCAAGAGGAGACTTACTATGG
GGAGTATATGAAGGCTTCAAAAACTTACTTCAACTAGGTTATATTATCGAAATACCAAAATTAATTGCAGTTGAACCTAT
ACCAAGAATTGAATCTGTTCTAAAAGGTAAGAGTTATATCAAAAAATTTAAAGGAGATTACTCAAAAACTCCTTCTATAG
GAGGTGATACTGTTACATATCAATCAATAAAGGCGATAAAAGAAACGAATGGATGTGCAATAACTGTAAATGCAGAGAAA
ATACCTTCCGCATTAAAATTAATTGGAAGTAGTGGTGTATACTTAGAAACATCTTCAGCACTAGCGATTCAGGGACTTTG
TATTCTTAGAGAAAAGGAAATTATTAATGAGAATAGTCGTGTACTTATGATTGCCACTTCACATGGATATAAAAACTAA

Upstream 100 bases:

>100_bases
TTCGTATCATCGATTGTTATAAACTATATTATTCGTTATACAAATGATACCATATATTATATTATAAAGATATAATTACT
TAGAAAACAGGAGGATTTTT

Downstream 100 bases:

>100_bases
GAAAGGGAATTTTATAATGAATAAAAAAGACACTTTTAATAGTTGATGTACAATTTGCAATGTTCTGTGATGAAAATAAT
AAACTGTATTAAGAGGAAAG

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MIERNKSIKNLYCIRCNKKYGISDYFRGCEKCLNDGLPASVTFHYEVGESVNNINEVFPYSMQSMLGEGNTPIISHKKIS
DIYGIESFYLKNEFQNPTGSHKDRMSPYIVARAIEMKRKGVVVASSGNAGISIASYASYKGVKSIVVTTKGINPVYKRAI
EATGAQIIITETSDERWNIVKKLVDIEGWYPATNYINPPVGSNPFGVQGYKKIAFEIYEFFNEKLPTHILIPVSRGDLLW
GVYEGFKNLLQLGYIIEIPKLIAVEPIPRIESVLKGKSYIKKFKGDYSKTPSIGGDTVTYQSIKAIKETNGCAITVNAEK
IPSALKLIGSSGVYLETSSALAIQGLCILREKEIINENSRVLMIATSHGYKN

Sequences:

>Translated_372_residues
MIERNKSIKNLYCIRCNKKYGISDYFRGCEKCLNDGLPASVTFHYEVGESVNNINEVFPYSMQSMLGEGNTPIISHKKIS
DIYGIESFYLKNEFQNPTGSHKDRMSPYIVARAIEMKRKGVVVASSGNAGISIASYASYKGVKSIVVTTKGINPVYKRAI
EATGAQIIITETSDERWNIVKKLVDIEGWYPATNYINPPVGSNPFGVQGYKKIAFEIYEFFNEKLPTHILIPVSRGDLLW
GVYEGFKNLLQLGYIIEIPKLIAVEPIPRIESVLKGKSYIKKFKGDYSKTPSIGGDTVTYQSIKAIKETNGCAITVNAEK
IPSALKLIGSSGVYLETSSALAIQGLCILREKEIINENSRVLMIATSHGYKN
>Mature_372_residues
MIERNKSIKNLYCIRCNKKYGISDYFRGCEKCLNDGLPASVTFHYEVGESVNNINEVFPYSMQSMLGEGNTPIISHKKIS
DIYGIESFYLKNEFQNPTGSHKDRMSPYIVARAIEMKRKGVVVASSGNAGISIASYASYKGVKSIVVTTKGINPVYKRAI
EATGAQIIITETSDERWNIVKKLVDIEGWYPATNYINPPVGSNPFGVQGYKKIAFEIYEFFNEKLPTHILIPVSRGDLLW
GVYEGFKNLLQLGYIIEIPKLIAVEPIPRIESVLKGKSYIKKFKGDYSKTPSIGGDTVTYQSIKAIKETNGCAITVNAEK
IPSALKLIGSSGVYLETSSALAIQGLCILREKEIINENSRVLMIATSHGYKN

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 41331; Mature: 41331

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIERNKSIKNLYCIRCNKKYGISDYFRGCEKCLNDGLPASVTFHYEVGESVNNINEVFPY
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCH
SMQSMLGEGNTPIISHKKISDIYGIESFYLKNEFQNPTGSHKDRMSPYIVARAIEMKRKG
HHHHHHCCCCCCEECCCHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
VVVASSGNAGISIASYASYKGVKSIVVTTKGINPVYKRAIEATGAQIIITETSDERWNIV
EEEEECCCCCEEEEHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCEEEEECCCCHHHHHH
KKLVDIEGWYPATNYINPPVGSNPFGVQGYKKIAFEIYEFFNEKLPTHILIPVSRGDLLW
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHH
GVYEGFKNLLQLGYIIEIPKLIAVEPIPRIESVLKGKSYIKKFKGDYSKTPSIGGDTVTY
HHHHHHHHHHHHCHHEECCHHEECCCCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCHH
QSIKAIKETNGCAITVNAEKIPSALKLIGSSGVYLETSSALAIQGLCILREKEIINENSR
HHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCEEEECCCCEEEHHEEEEEHHHHHCCCCC
VLMIATSHGYKN
EEEEEECCCCCC
>Mature Secondary Structure
MIERNKSIKNLYCIRCNKKYGISDYFRGCEKCLNDGLPASVTFHYEVGESVNNINEVFPY
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCH
SMQSMLGEGNTPIISHKKISDIYGIESFYLKNEFQNPTGSHKDRMSPYIVARAIEMKRKG
HHHHHHCCCCCCEECCCHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
VVVASSGNAGISIASYASYKGVKSIVVTTKGINPVYKRAIEATGAQIIITETSDERWNIV
EEEEECCCCCEEEEHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCEEEEECCCCHHHHHH
KKLVDIEGWYPATNYINPPVGSNPFGVQGYKKIAFEIYEFFNEKLPTHILIPVSRGDLLW
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHH
GVYEGFKNLLQLGYIIEIPKLIAVEPIPRIESVLKGKSYIKKFKGDYSKTPSIGGDTVTY
HHHHHHHHHHHHCHHEECCHHEECCCCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCHH
QSIKAIKETNGCAITVNAEKIPSALKLIGSSGVYLETSSALAIQGLCILREKEIINENSR
HHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCEEEECCCCEEEHHEEEEEHHHHHCCCCC
VLMIATSHGYKN
EEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]