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The map label for this gene is nirC [H]

Identifier: 226948230

GI number: 226948230

Start: 1146845

End: 1147609

Strand: Direct

Name: nirC [H]

Synonym: CLM_1107

Alternate gene names: 226948230

Gene position: 1146845-1147609 (Clockwise)

Preceding gene: 226948229

Following gene: 226948231

Centisome position: 27.6

GC content: 31.37

Gene sequence:

>765_bases
ATGTATAGTGAAGAAATTAACAAAATTAGTAATGTTGCAGAAAGCAAAAGGGACTTATTAAGAAATAACAAAGCAGGCTA
TTTAGTATCTTCTGCTCTTGCAGGTATATACGTTGGCATAGGTATTATACTCATATTTACATTAGGCGGAAATTTAGCAT
CTGTTAATTCCCCTTATGTAAAGCTTATTATGGGGTTATCCTTTGGTATAGCTTTAAGTCTTGTTATTATGGCGGGATCA
GAACTTTTTACAGGAAATAATATGGTTATGACTATAGGAACATTAAATAAGAAGACTACATGGAAAGATACCTTAAGCAT
ATGGGGATTCAGTTTTGTAGGAAATTTAATAGGATCAATGCTTTTAGCTTTAATATTTGTTAATGCAGGATTAGCGGAAG
GAGCTGTAGGTAAATTTATTTTAAAAACAGCAGAAATAAAGATGACACTACCCCCTATGGAGTTATTTTTAAGAGGTTTG
TTGTGTAATATTTTAGTCTGTTTAGCTGTGTGGTGTAGTTTAAAAATGAGAGAAGAGGTAGGAAAACTCATAATGATATT
TTGGTGCTTATTTGCCTTTATATCATCAGGTTTTGAACATAGTGTAGCAAATATGACATTACTTTCTATAGCTCTATTTA
TACCACATGGATTAGGAGTATCCATAAGTGGATTAGCGTACAATTTAATTTTTGTTTCTTTAGGAAATATTATAGGCGGA
GCATTATTTGTAGGAGCAGCCTATTATAAAATATCAAAAAAATAG

Upstream 100 bases:

>100_bases
ATTTTTATCACATACTTTTTTTATTTTACAATGTAGAATAAATTATAAGCAGTAATAAATTTTATATAATGCATAAAAAA
ATAAAAGGGGGTTCTATGAT

Downstream 100 bases:

>100_bases
TTTTAAGAGGTGAAACATAATGGGTTTTAAGATTAGAAAAGAAAATTTTAATAATGTTTTAAAAAATTTAAGAAAAGATT
TTAAAGTTTATGCACCGACT

Product: formate/nitrite transporter family protein

Products: Proton [Cytoplasm]; nitrite [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MYSEEINKISNVAESKRDLLRNNKAGYLVSSALAGIYVGIGIILIFTLGGNLASVNSPYVKLIMGLSFGIALSLVIMAGS
ELFTGNNMVMTIGTLNKKTTWKDTLSIWGFSFVGNLIGSMLLALIFVNAGLAEGAVGKFILKTAEIKMTLPPMELFLRGL
LCNILVCLAVWCSLKMREEVGKLIMIFWCLFAFISSGFEHSVANMTLLSIALFIPHGLGVSISGLAYNLIFVSLGNIIGG
ALFVGAAYYKISKK

Sequences:

>Translated_254_residues
MYSEEINKISNVAESKRDLLRNNKAGYLVSSALAGIYVGIGIILIFTLGGNLASVNSPYVKLIMGLSFGIALSLVIMAGS
ELFTGNNMVMTIGTLNKKTTWKDTLSIWGFSFVGNLIGSMLLALIFVNAGLAEGAVGKFILKTAEIKMTLPPMELFLRGL
LCNILVCLAVWCSLKMREEVGKLIMIFWCLFAFISSGFEHSVANMTLLSIALFIPHGLGVSISGLAYNLIFVSLGNIIGG
ALFVGAAYYKISKK
>Mature_254_residues
MYSEEINKISNVAESKRDLLRNNKAGYLVSSALAGIYVGIGIILIFTLGGNLASVNSPYVKLIMGLSFGIALSLVIMAGS
ELFTGNNMVMTIGTLNKKTTWKDTLSIWGFSFVGNLIGSMLLALIFVNAGLAEGAVGKFILKTAEIKMTLPPMELFLRGL
LCNILVCLAVWCSLKMREEVGKLIMIFWCLFAFISSGFEHSVANMTLLSIALFIPHGLGVSISGLAYNLIFVSLGNIIGG
ALFVGAAYYKISKK

Specific function: May act as a nitrite transporter [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI87082249, Length=256, Percent_Identity=44.53125, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1787132, Length=238, Percent_Identity=30.2521008403361, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788837, Length=239, Percent_Identity=30.5439330543933, Blast_Score=81, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6321779, Length=224, Percent_Identity=30.3571428571429, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 27341; Mature: 27341

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS01005 FORMATE_NITRITE_TP_1 ; PS01006 FORMATE_NITRITE_TP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSEEINKISNVAESKRDLLRNNKAGYLVSSALAGIYVGIGIILIFTLGGNLASVNSPYV
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
KLIMGLSFGIALSLVIMAGSELFTGNNMVMTIGTLNKKTTWKDTLSIWGFSFVGNLIGSM
HHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
LLALIFVNAGLAEGAVGKFILKTAEIKMTLPPMELFLRGLLCNILVCLAVWCSLKMREEV
HHHHHHHHCCCCCCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKLIMIFWCLFAFISSGFEHSVANMTLLSIALFIPHGLGVSISGLAYNLIFVSLGNIIGG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHH
ALFVGAAYYKISKK
HHHHHHHHHHCCCC
>Mature Secondary Structure
MYSEEINKISNVAESKRDLLRNNKAGYLVSSALAGIYVGIGIILIFTLGGNLASVNSPYV
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
KLIMGLSFGIALSLVIMAGSELFTGNNMVMTIGTLNKKTTWKDTLSIWGFSFVGNLIGSM
HHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
LLALIFVNAGLAEGAVGKFILKTAEIKMTLPPMELFLRGLLCNILVCLAVWCSLKMREEV
HHHHHHHHCCCCCCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKLIMIFWCLFAFISSGFEHSVANMTLLSIALFIPHGLGVSISGLAYNLIFVSLGNIIGG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHH
ALFVGAAYYKISKK
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; nitrite [Periplasm] [C]

Specific reaction: Proton [Periplasm] + nitrite [Periplasm] = Proton [Cytoplasm] + nitrite [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1987123; 11677609 [H]