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The map label for this gene is mraY [H]

Identifier: 226948153

GI number: 226948153

Start: 1079157

End: 1080110

Strand: Reverse

Name: mraY [H]

Synonym: CLM_1023

Alternate gene names: 226948153

Gene position: 1080110-1079157 (Counterclockwise)

Preceding gene: 226948154

Following gene: 226948146

Centisome position: 25.99

GC content: 26.73

Gene sequence:

>954_bases
ATGAGTACTATTATATATGCTGTATTATTCAGTTTTTTATTATCTACAATTACTAGTTTGTTTCTTATACCATTATTTAA
AAAATTAAATTTAGGACAAAGCATTAAAAATGGAATTCCGATAAGCCATAAAAAGAAGGCTGGAACTCCTACATTTGGTG
GTATTATTTTTATTTTTTCATCAATAATAACAATGTTATTTATCATAAAAAATTATAATAAAGAACTCTTGCTTGTAATA
TCTTCACTTATTGCTTTTGGACTGATAGGTTTTATTGATGATACTTTAAAGAAAATACATAAAAAAAATGAAGGATTAAC
TTCAAAAGGAAAAATGATTTTATTACTTTTTGTATCAAGTATTTTTGCCATTTACTCATACTATAATCCTTCGATTGGTT
CAATAATTATGTTTCCATTTACTAAAAAACTATTTGACTTAAGAATTTTATACATACCCTTTATTATTTTTTATTATGTA
TCAACAACTAATGCATTAAACTTAACAGACGGTTTGGACGGACTTGCTACTTCTATAACACTACTTGTAGTAACATTTTT
TATTTTTCTATCTTCTGGAATGGGGCATTATACATTATCAATTAGTTGCGGTTGTATAGCAGGGGCTTTATTAGGATTCT
TACGATATAATTGTTATCCCGCTAAAATAATTATGGGGGATACTGGTTCTTTAGCCCTTGGTGGTGCTATTGCAACAATA
GCTATGATACTCAAAAACCCATTTATTGTTATTATTGTTGGAGGAATTTATGTTATTGAAGCATTATCATCATTAATTCA
AATAGTATTTTTTAAACTATTTGGTAAACGTATTTTTAAAATGGCTCCTATTCATCACTCACTTGAATTACATGGCTGGC
ATGAAACCAAGATAGTTTCAGTATTTTCTATAATAACAACAATTTTATGTCTTATTGGATTTCTATCTATGTAA

Upstream 100 bases:

>100_bases
ACTAGAAGCTATATATTTATAACAAATTACACTATAGAAATTACAACATTATTAAGAACTTAATAGACGTTAAGAAATAT
TAAGTTAGAAAGGATTTACT

Downstream 100 bases:

>100_bases
TTAACAGTATTACTTCTGAACATAACAAGCTTACTCCACTGATTAAAGCCTGAAAATTGTAGATACTGTCACAATAATAA
ATTATACTTACTATGGAAAA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSTIIYAVLFSFLLSTITSLFLIPLFKKLNLGQSIKNGIPISHKKKAGTPTFGGIIFIFSSIITMLFIIKNYNKELLLVI
SSLIAFGLIGFIDDTLKKIHKKNEGLTSKGKMILLLFVSSIFAIYSYYNPSIGSIIMFPFTKKLFDLRILYIPFIIFYYV
STTNALNLTDGLDGLATSITLLVVTFFIFLSSGMGHYTLSISCGCIAGALLGFLRYNCYPAKIIMGDTGSLALGGAIATI
AMILKNPFIVIIVGGIYVIEALSSLIQIVFFKLFGKRIFKMAPIHHSLELHGWHETKIVSVFSIITTILCLIGFLSM

Sequences:

>Translated_317_residues
MSTIIYAVLFSFLLSTITSLFLIPLFKKLNLGQSIKNGIPISHKKKAGTPTFGGIIFIFSSIITMLFIIKNYNKELLLVI
SSLIAFGLIGFIDDTLKKIHKKNEGLTSKGKMILLLFVSSIFAIYSYYNPSIGSIIMFPFTKKLFDLRILYIPFIIFYYV
STTNALNLTDGLDGLATSITLLVVTFFIFLSSGMGHYTLSISCGCIAGALLGFLRYNCYPAKIIMGDTGSLALGGAIATI
AMILKNPFIVIIVGGIYVIEALSSLIQIVFFKLFGKRIFKMAPIHHSLELHGWHETKIVSVFSIITTILCLIGFLSM
>Mature_316_residues
STIIYAVLFSFLLSTITSLFLIPLFKKLNLGQSIKNGIPISHKKKAGTPTFGGIIFIFSSIITMLFIIKNYNKELLLVIS
SLIAFGLIGFIDDTLKKIHKKNEGLTSKGKMILLLFVSSIFAIYSYYNPSIGSIIMFPFTKKLFDLRILYIPFIIFYYVS
TTNALNLTDGLDGLATSITLLVVTFFIFLSSGMGHYTLSISCGCIAGALLGFLRYNCYPAKIIMGDTGSLALGGAIATIA
MILKNPFIVIIVGGIYVIEALSSLIQIVFFKLFGKRIFKMAPIHHSLELHGWHETKIVSVFSIITTILCLIGFLSM

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=334, Percent_Identity=38.3233532934132, Blast_Score=210, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 34984; Mature: 34853

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIIYAVLFSFLLSTITSLFLIPLFKKLNLGQSIKNGIPISHKKKAGTPTFGGIIFIFS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHH
SIITMLFIIKNYNKELLLVISSLIAFGLIGFIDDTLKKIHKKNEGLTSKGKMILLLFVSS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
IFAIYSYYNPSIGSIIMFPFTKKLFDLRILYIPFIIFYYVSTTNALNLTDGLDGLATSIT
HHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHH
LLVVTFFIFLSSGMGHYTLSISCGCIAGALLGFLRYNCYPAKIIMGDTGSLALGGAIATI
HHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHH
AMILKNPFIVIIVGGIYVIEALSSLIQIVFFKLFGKRIFKMAPIHHSLELHGWHETKIVS
HHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHH
VFSIITTILCLIGFLSM
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STIIYAVLFSFLLSTITSLFLIPLFKKLNLGQSIKNGIPISHKKKAGTPTFGGIIFIFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHH
SIITMLFIIKNYNKELLLVISSLIAFGLIGFIDDTLKKIHKKNEGLTSKGKMILLLFVSS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
IFAIYSYYNPSIGSIIMFPFTKKLFDLRILYIPFIIFYYVSTTNALNLTDGLDGLATSIT
HHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHH
LLVVTFFIFLSSGMGHYTLSISCGCIAGALLGFLRYNCYPAKIIMGDTGSLALGGAIATI
HHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHH
AMILKNPFIVIIVGGIYVIEALSSLIQIVFFKLFGKRIFKMAPIHHSLELHGWHETKIVS
HHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHH
VFSIITTILCLIGFLSM
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA