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The map label for this gene is arsC1 [H]

Identifier: 226948047

GI number: 226948047

Start: 967804

End: 968217

Strand: Direct

Name: arsC1 [H]

Synonym: CLM_0908

Alternate gene names: 226948047

Gene position: 967804-968217 (Clockwise)

Preceding gene: 226948046

Following gene: 226948048

Centisome position: 23.29

GC content: 29.71

Gene sequence:

>414_bases
ATGAAACCAAAAGTAGCATTTATATGTGTTCATAATTCTTGTAGATCTCAAATGGCAGAAGCATTAGGAAGGTTGTTTGC
ATCTGATGTCTTTCATTCATATTCCGCCGGTACAGAAACTAAAGTGCAAATAAATCAAGATGCAGTAAGAATTATAAATG
ATATGTATGGAGTAGATATGAATAAAGAGCATAGGTCTAAATTAATAACTGATATACCAGAAGTTGATATTGCTATAAAA
ATGGGATGTAATGTTGTATGTCCTTTTTTACCATCCAAGCATACGGAAGATTGGGGCTTAGAAGATCCTACTGGTAAAAG
TGATGAAGAATTTATTAAAACAGCAAAAGCTATTGAAGAAAAGATTAAAGATTTATCGGAAAGAATAAAAAATAATAAAA
TTAATTTAATGTAA

Upstream 100 bases:

>100_bases
AACTAGGCATAATTCCACTGCAAAATTTAAGAACCAATTTTGCAGTGGAATTATATATACACATGGTTATATAAAAATAA
TTTGTACGGAGGATAATTTC

Downstream 100 bases:

>100_bases
TAATTTGTATTAAACTATTAATTTTTATAAAGGAGAACTAATTATGTCTTTAAAAAGTAAAGAAAAAAATAAGGGCTTAG
GTATCTTTGAAAGATATCTT

Product: arsenate reductase ArsC

Products: NA

Alternate protein names: Arsenate reductase 1; Arsenical pump modifier 1; Low molecular weight protein-tyrosine-phosphatase 1 [H]

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MKPKVAFICVHNSCRSQMAEALGRLFASDVFHSYSAGTETKVQINQDAVRIINDMYGVDMNKEHRSKLITDIPEVDIAIK
MGCNVVCPFLPSKHTEDWGLEDPTGKSDEEFIKTAKAIEEKIKDLSERIKNNKINLM

Sequences:

>Translated_137_residues
MKPKVAFICVHNSCRSQMAEALGRLFASDVFHSYSAGTETKVQINQDAVRIINDMYGVDMNKEHRSKLITDIPEVDIAIK
MGCNVVCPFLPSKHTEDWGLEDPTGKSDEEFIKTAKAIEEKIKDLSERIKNNKINLM
>Mature_137_residues
MKPKVAFICVHNSCRSQMAEALGRLFASDVFHSYSAGTETKVQINQDAVRIINDMYGVDMNKEHRSKLITDIPEVDIAIK
MGCNVVCPFLPSKHTEDWGLEDPTGKSDEEFIKTAKAIEEKIKDLSERIKNNKINLM

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15472; Mature: 15472

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKVAFICVHNSCRSQMAEALGRLFASDVFHSYSAGTETKVQINQDAVRIINDMYGVDM
CCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCC
NKEHRSKLITDIPEVDIAIKMGCNVVCPFLPSKHTEDWGLEDPTGKSDEEFIKTAKAIEE
CHHHHHHHHHCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KIKDLSERIKNNKINLM
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKPKVAFICVHNSCRSQMAEALGRLFASDVFHSYSAGTETKVQINQDAVRIINDMYGVDM
CCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCC
NKEHRSKLITDIPEVDIAIKMGCNVVCPFLPSKHTEDWGLEDPTGKSDEEFIKTAKAIEE
CHHHHHHHHHCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KIKDLSERIKNNKINLM
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA