Click here to switch to the map view.

The map label for this gene is resE [H]

Identifier: 226947967

GI number: 226947967

Start: 887832

End: 888881

Strand: Direct

Name: resE [H]

Synonym: CLM_0826

Alternate gene names: 226947967

Gene position: 887832-888881 (Clockwise)

Preceding gene: 226947966

Following gene: 226947968

Centisome position: 21.37

GC content: 34.95

Gene sequence:

>1050_bases
TTGGGGTGTACGATGAAAATATTGGCAAACAGGAAAATCAAAAAACTTTTCCGTTTGGTATTGCTGTTTATAGTAGCATT
CACCTTGATTTCTGCTGTTTTCATAGTTTTGAAATTTGAAACTGCAGCATTGTGTATATTGGTATGTTCTTTGTGCATGA
GTATTTTGATATTGGCAATAGGTTATAGGTATTTCAAGGAACAAAATATAATCATGGAAAATGCGGTAACGCAAATCAAA
GAATATATTTCTGGAAATCAAAACGCACGTATTGAATGTGATGAAGAAGGAGAACTATACAGACTATTTCATGAAGTAAA
TTCCTTAGTTTCTATTTTAAATGCCCACGCTGAAAATGAGGGAAAAGCAAAAAAATTTTTAAAAGATACCATTTCCGATA
TTTCCCACCAGTTAAAAACTCCGCTTGCTGCCCTTAATATCTATAATGGAATTATGCAAGAAGAAGCAAAGAGTTTACCG
ACAATCAAAGAGTTTACTGTTCTTTCAGAGCAGGAGCTTGATAGAATAGAAATACTGGTGCAAAACCTCTTGAAAATTAC
AAAACTTGATGCCGGAACAATCGTGATTGAGAAAGCTGAAGAAAATGTATCTGAAATGATGGGCAGTATAGAAAGGCACT
TTTCATTTCGTGCCAAGCAGGAGAAAAAGGAAATATATCTGTCCGGTGATGATGAAGTCACCTTATTATGTGACCGTAAT
TGGATAATTGAAGCAATCAGTAATATTGTTAAAAACGCTTTTGACCATACGAAAAAAGGAAATGCTATCTATATTGAATG
GAAACAATTTGCGTCTGTTATTCAAGTCATCATAAAAGACAACGGAAACGGTATTCACCCAGAGGATTTGCACCATATTT
TCAAAAGATTTTATCGCAGTCGTTTTTCTAAAGACACGCAAGGTATCGGACTTGGGTTACCGCTTGCGAAAGCTATTGTT
GAAGCACACAGCGGAACAATCGAAGTTGACAGCGAATTGGGTATTGGCACTACTTTTACAATCAATTTTTTAATTCCTAC
AAAATTGTAG

Upstream 100 bases:

>100_bases
TATATATACGCAGACTGCGTACAAAAATCGAAGATAATCCGGGAGAGCCTCAAAAAATAGTGACTGTTCGGCGTATGGGG
TATAAATGGAGTACTGTTGA

Downstream 100 bases:

>100_bases
GGTAAGTGTCATATAGTAGTAAGATTGACATGATAATCTTTCAATATCAAGACAGAAAGAGGTAGATAACCTATGAATTT
ATTGGAAGTTAAATCAATTT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MGCTMKILANRKIKKLFRLVLLFIVAFTLISAVFIVLKFETAALCILVCSLCMSILILAIGYRYFKEQNIIMENAVTQIK
EYISGNQNARIECDEEGELYRLFHEVNSLVSILNAHAENEGKAKKFLKDTISDISHQLKTPLAALNIYNGIMQEEAKSLP
TIKEFTVLSEQELDRIEILVQNLLKITKLDAGTIVIEKAEENVSEMMGSIERHFSFRAKQEKKEIYLSGDDEVTLLCDRN
WIIEAISNIVKNAFDHTKKGNAIYIEWKQFASVIQVIIKDNGNGIHPEDLHHIFKRFYRSRFSKDTQGIGLGLPLAKAIV
EAHSGTIEVDSELGIGTTFTINFLIPTKL

Sequences:

>Translated_349_residues
MGCTMKILANRKIKKLFRLVLLFIVAFTLISAVFIVLKFETAALCILVCSLCMSILILAIGYRYFKEQNIIMENAVTQIK
EYISGNQNARIECDEEGELYRLFHEVNSLVSILNAHAENEGKAKKFLKDTISDISHQLKTPLAALNIYNGIMQEEAKSLP
TIKEFTVLSEQELDRIEILVQNLLKITKLDAGTIVIEKAEENVSEMMGSIERHFSFRAKQEKKEIYLSGDDEVTLLCDRN
WIIEAISNIVKNAFDHTKKGNAIYIEWKQFASVIQVIIKDNGNGIHPEDLHHIFKRFYRSRFSKDTQGIGLGLPLAKAIV
EAHSGTIEVDSELGIGTTFTINFLIPTKL
>Mature_348_residues
GCTMKILANRKIKKLFRLVLLFIVAFTLISAVFIVLKFETAALCILVCSLCMSILILAIGYRYFKEQNIIMENAVTQIKE
YISGNQNARIECDEEGELYRLFHEVNSLVSILNAHAENEGKAKKFLKDTISDISHQLKTPLAALNIYNGIMQEEAKSLPT
IKEFTVLSEQELDRIEILVQNLLKITKLDAGTIVIEKAEENVSEMMGSIERHFSFRAKQEKKEIYLSGDDEVTLLCDRNW
IIEAISNIVKNAFDHTKKGNAIYIEWKQFASVIQVIIKDNGNGIHPEDLHHIFKRFYRSRFSKDTQGIGLGLPLAKAIVE
AHSGTIEVDSELGIGTTFTINFLIPTKL

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=239, Percent_Identity=31.3807531380753, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=26.2948207171315, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1786783, Length=214, Percent_Identity=29.4392523364486, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790346, Length=216, Percent_Identity=29.1666666666667, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1788279, Length=293, Percent_Identity=24.2320819112628, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789149, Length=335, Percent_Identity=24.7761194029851, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI145693157, Length=230, Percent_Identity=24.7826086956522, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=25.2293577981651, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788549, Length=217, Percent_Identity=27.6497695852535, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=321, Percent_Identity=23.98753894081, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786912, Length=216, Percent_Identity=25.462962962963, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=23.2, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=24.7863247863248, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789403, Length=198, Percent_Identity=25.7575757575758, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39515; Mature: 39383

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGCTMKILANRKIKKLFRLVLLFIVAFTLISAVFIVLKFETAALCILVCSLCMSILILAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYRYFKEQNIIMENAVTQIKEYISGNQNARIECDEEGELYRLFHEVNSLVSILNAHAENE
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
GKAKKFLKDTISDISHQLKTPLAALNIYNGIMQEEAKSLPTIKEFTVLSEQELDRIEILV
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHH
QNLLKITKLDAGTIVIEKAEENVSEMMGSIERHFSFRAKQEKKEIYLSGDDEVTLLCDRN
HHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCC
WIIEAISNIVKNAFDHTKKGNAIYIEWKQFASVIQVIIKDNGNGIHPEDLHHIFKRFYRS
HHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RFSKDTQGIGLGLPLAKAIVEAHSGTIEVDSELGIGTTFTINFLIPTKL
HHCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEEECCCC
>Mature Secondary Structure 
GCTMKILANRKIKKLFRLVLLFIVAFTLISAVFIVLKFETAALCILVCSLCMSILILAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYRYFKEQNIIMENAVTQIKEYISGNQNARIECDEEGELYRLFHEVNSLVSILNAHAENE
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
GKAKKFLKDTISDISHQLKTPLAALNIYNGIMQEEAKSLPTIKEFTVLSEQELDRIEILV
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHH
QNLLKITKLDAGTIVIEKAEENVSEMMGSIERHFSFRAKQEKKEIYLSGDDEVTLLCDRN
HHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCC
WIIEAISNIVKNAFDHTKKGNAIYIEWKQFASVIQVIIKDNGNGIHPEDLHHIFKRFYRS
HHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RFSKDTQGIGLGLPLAKAIVEAHSGTIEVDSELGIGTTFTINFLIPTKL
HHCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]