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The map label for this gene is lytT [H]

Identifier: 226947879

GI number: 226947879

Start: 789248

End: 790006

Strand: Direct

Name: lytT [H]

Synonym: CLM_0734

Alternate gene names: 226947879

Gene position: 789248-790006 (Clockwise)

Preceding gene: 226947878

Following gene: 226947880

Centisome position: 18.99

GC content: 28.06

Gene sequence:

>759_bases
ATGACTATAGAGGAGTACATGAAGTTTTTTTCTAGTCTTTTGTTTTCAAAGGTAGATTATAAAGAGATAATGTTAAAATT
TGCATTACTAGACATTGGGAATAAAAAAATAAAAGATTTAAACTATTCTCAAAAAAGAAGATTAAGCTTTGCAAGAGAGA
GATTAAAACAGCCCAAATTTTTAATATTTCAGGAGCCAATTCTTAATATGGATAGAGATGGAGCTAAAGTGATAATAGAA
AATATAGAGGATTTAAAGTCTAATGGAACTGCTATTTTAATTACATCCGTGGTATTTAAAGATACACTTATGCTTAGTGA
AAAGGCTTATAGATTAAATGATGAGGGATTAGTAGAGTTAGATAACAGCTTAGAGGAATCTAAAAATGAGAGAGAAGAGG
TTTTAGATAAAAAACCAGTATATAAAATAGAAAAAATTCCTGCCAAATTAGATGAAAGAATTTTATTATTTGATCCTATA
GAGATTGATTACATAGAAAGCCAACAGGGAGTTAGTAATTTAACCATTAGAGGGGACAAGTTTCCTTGTACTATTTCTCT
TACTGATCTAGAGGAGAGATTAAAATATTTTGGATTTTTTAGATGTCATAGATCCTATTTAGTAAATTTGCAAAGAGTGA
AGGAAGTAATTACTTGGACAAGAAATAGTTACACTTTAAGTTTAGATGATAAAGTAAAGAGTTCTATTCCTTTGTCTAAA
AGAAGATTAGAGGAACTAAAGGATATATTAAATCTATAA

Upstream 100 bases:

>100_bases
GGGTGAAATATGCCTAGAAGATATAAAAAATTTAGATTATATTAAGACTAATATTAGTGATATTGGGGTTGTACTTAGAG
AAGGGAGCTTTTACGATAGA

Downstream 100 bases:

>100_bases
AAATTATATTAAAATTTAACTCATGATATTGAGAAGGCTAAAAATATTAAATTCAGATTATGAAATTATATTAAGATTTA
AAATGTAAATTTTATATTAA

Product: LytR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MTIEEYMKFFSSLLFSKVDYKEIMLKFALLDIGNKKIKDLNYSQKRRLSFARERLKQPKFLIFQEPILNMDRDGAKVIIE
NIEDLKSNGTAILITSVVFKDTLMLSEKAYRLNDEGLVELDNSLEESKNEREEVLDKKPVYKIEKIPAKLDERILLFDPI
EIDYIESQQGVSNLTIRGDKFPCTISLTDLEERLKYFGFFRCHRSYLVNLQRVKEVITWTRNSYTLSLDDKVKSSIPLSK
RRLEELKDILNL

Sequences:

>Translated_252_residues
MTIEEYMKFFSSLLFSKVDYKEIMLKFALLDIGNKKIKDLNYSQKRRLSFARERLKQPKFLIFQEPILNMDRDGAKVIIE
NIEDLKSNGTAILITSVVFKDTLMLSEKAYRLNDEGLVELDNSLEESKNEREEVLDKKPVYKIEKIPAKLDERILLFDPI
EIDYIESQQGVSNLTIRGDKFPCTISLTDLEERLKYFGFFRCHRSYLVNLQRVKEVITWTRNSYTLSLDDKVKSSIPLSK
RRLEELKDILNL
>Mature_251_residues
TIEEYMKFFSSLLFSKVDYKEIMLKFALLDIGNKKIKDLNYSQKRRLSFARERLKQPKFLIFQEPILNMDRDGAKVIIEN
IEDLKSNGTAILITSVVFKDTLMLSEKAYRLNDEGLVELDNSLEESKNEREEVLDKKPVYKIEKIPAKLDERILLFDPIE
IDYIESQQGVSNLTIRGDKFPCTISLTDLEERLKYFGFFRCHRSYLVNLQRVKEVITWTRNSYTLSLDDKVKSSIPLSKR
RLEELKDILNL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=102, Percent_Identity=30.3921568627451, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 29665; Mature: 29534

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIEEYMKFFSSLLFSKVDYKEIMLKFALLDIGNKKIKDLNYSQKRRLSFARERLKQPKF
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHCCCCE
LIFQEPILNMDRDGAKVIIENIEDLKSNGTAILITSVVFKDTLMLSEKAYRLNDEGLVEL
EEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCEEE
DNSLEESKNEREEVLDKKPVYKIEKIPAKLDERILLFDPIEIDYIESQQGVSNLTIRGDK
HHHHHHHHHHHHHHHCCCCCHHHHHCCHHHCCEEEEECCCEEEEECCCCCCCEEEEECCC
FPCTISLTDLEERLKYFGFFRCHRSYLVNLQRVKEVITWTRNSYTLSLDDKVKSSIPLSK
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHCCCHHH
RRLEELKDILNL
HHHHHHHHHHCC
>Mature Secondary Structure 
TIEEYMKFFSSLLFSKVDYKEIMLKFALLDIGNKKIKDLNYSQKRRLSFARERLKQPKF
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHCCCCE
LIFQEPILNMDRDGAKVIIENIEDLKSNGTAILITSVVFKDTLMLSEKAYRLNDEGLVEL
EEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCEEE
DNSLEESKNEREEVLDKKPVYKIEKIPAKLDERILLFDPIEIDYIESQQGVSNLTIRGDK
HHHHHHHHHHHHHHHCCCCCHHHHHCCHHHCCEEEEECCCEEEEECCCCCCCEEEEECCC
FPCTISLTDLEERLKYFGFFRCHRSYLVNLQRVKEVITWTRNSYTLSLDDKVKSSIPLSK
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHCCCHHH
RRLEELKDILNL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]