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The map label for this gene is lepB [H]

Identifier: 226947830

GI number: 226947830

Start: 737927

End: 738535

Strand: Direct

Name: lepB [H]

Synonym: CLM_0685

Alternate gene names: 226947830

Gene position: 737927-738535 (Clockwise)

Preceding gene: 226947829

Following gene: 226947831

Centisome position: 17.76

GC content: 27.59

Gene sequence:

>609_bases
ATGGATAAGAGAAAAGTTAAAAAAGAGATTGAAAGTTGGATTTTTTCTATTTTAGGGGCTATTCTTATTGCAGGTTTAGT
TAATAGTAAGGTTTTTGCAAAGGTTCGAGTACAACAAAGCTCTATGGAGAATACTTTGCTTACTAATGAACAATTAGTAG
TAGATAAATTAAGTTATAATTTTGTAGAACCTAAAAAAGGAGATATAATTATTTTTCATGAAAATAAAGAAAAGGGAACT
ATAGCTGAGGATACTTTAGAAATGGTAGATAATATAATATCCATATTTAATAATAACAATAATTATATAGAAAAAGATGA
TAGATTAATTAAAAGAGTAATTGGTATTCCAGGGGATGAAATTGATATTAAAGATGGGTATTTATATTTAAACGGCAAAA
AACTTGAAGAACCCTATGTAAAAGGGGAGACTATTCAAAGAGAATTTAAACTTCCTGTTCAGGTTCCAGAAAACAAATTG
TTTGTTTTAGGTGATAACAGAATGATAAGTAAAGATAGTAGAATTTTTGGGCTTATTGATTATAAACAAGTAGAAGGTAA
GGCAATATACAGGGTATATCCTTTCGATCACATAGGAAAGATAAAGTAA

Upstream 100 bases:

>100_bases
ATTAGCTATTTTTATTATGATAAGAGAAATTAATTAATGTTTAAATTAATTACTATCATAGCATTGTGATTTAATTTTTA
AATTAGAGGGGGAAAATATT

Downstream 100 bases:

>100_bases
AATTGACTATAAATATTGTGCTTAGATAACTTTGTTATTATAATAATTTAAAAACTAAATTAAAATTACAAAAAATTAAA
GTGGTATTTATTTTTAGTAA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase IB; Leader peptidase IB [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MDKRKVKKEIESWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYNFVEPKKGDIIIFHENKEKGT
IAEDTLEMVDNIISIFNNNNNYIEKDDRLIKRVIGIPGDEIDIKDGYLYLNGKKLEEPYVKGETIQREFKLPVQVPENKL
FVLGDNRMISKDSRIFGLIDYKQVEGKAIYRVYPFDHIGKIK

Sequences:

>Translated_202_residues
MDKRKVKKEIESWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYNFVEPKKGDIIIFHENKEKGT
IAEDTLEMVDNIISIFNNNNNYIEKDDRLIKRVIGIPGDEIDIKDGYLYLNGKKLEEPYVKGETIQREFKLPVQVPENKL
FVLGDNRMISKDSRIFGLIDYKQVEGKAIYRVYPFDHIGKIK
>Mature_202_residues
MDKRKVKKEIESWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYNFVEPKKGDIIIFHENKEKGT
IAEDTLEMVDNIISIFNNNNNYIEKDDRLIKRVIGIPGDEIDIKDGYLYLNGKKLEEPYVKGETIQREFKLPVQVPENKL
FVLGDNRMISKDSRIFGLIDYKQVEGKAIYRVYPFDHIGKIK

Specific function: Essential for cell viability [H]

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 23326; Mature: 23326

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKRKVKKEIESWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHCCCHHHCCCCEEEEEECCCC
FVEPKKGDIIIFHENKEKGTIAEDTLEMVDNIISIFNNNNNYIEKDDRLIKRVIGIPGDE
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHCCCCCE
IDIKDGYLYLNGKKLEEPYVKGETIQREFKLPVQVPENKLFVLGDNRMISKDSRIFGLID
EEEECCEEEECCCCCCCCCCCCCHHHHHCCCCEECCCCEEEEEECCEEECCCCCEEEEEE
YKQVEGKAIYRVYPFDHIGKIK
EEECCCEEEEEECCCHHCCCCC
>Mature Secondary Structure
MDKRKVKKEIESWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHCCCHHHCCCCEEEEEECCCC
FVEPKKGDIIIFHENKEKGTIAEDTLEMVDNIISIFNNNNNYIEKDDRLIKRVIGIPGDE
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHCCCCCE
IDIKDGYLYLNGKKLEEPYVKGETIQREFKLPVQVPENKLFVLGDNRMISKDSRIFGLID
EEEECCEEEECCCCCCCCCCCCCHHHHHCCCCEECCCCEEEEEECCEEECCCCCEEEEEE
YKQVEGKAIYRVYPFDHIGKIK
EEECCCEEEEEECCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA