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The map label for this gene is ybiR [C]

Identifier: 226947740

GI number: 226947740

Start: 634351

End: 635613

Strand: Reverse

Name: ybiR [C]

Synonym: CLM_0589

Alternate gene names: 226947740

Gene position: 635613-634351 (Counterclockwise)

Preceding gene: 226947741

Following gene: 226947739

Centisome position: 15.3

GC content: 30.96

Gene sequence:

>1263_bases
ATGATGCTTCCAGCAATTATATTTATAATAGTTTATGCATTAATTATTTCAGAAAAAGTAAACAGGGTTGTTGCTTCGCT
AGGCGGAGCTGCTATTATGCTTATATTAAAATTAATCACCCAAGAAAAGGCTTTCTTAAAAATTGATTTTAATACTATAG
GCCTATTAGTTGGAATGATGATTATAGTAAATATAACTAAAAGAACAGGTGTCTTTGAGTATATAGCTATAAAAGCAGCT
AAATTTTCCAAAGGGAATCCTATTAAAATATTAATACTATTTTCTGTAATAACTGCTGTTTTATCTGGAGTATTAGACAA
CGTTACTACCGTGCTTTTAATAGTACCTGTAACCTTAGTTATAACTAAAACATTAGAAATAGACCCGATTCCTTTTTTAA
TGTGTGAAATATTTGCATCTAACATAGGAGGCACTGCTACTTTAATAGGAGATCCACCAAACTTAATGATAGGAAGTGCT
GCTGGATTAAGCTTTTTAGATTTTGTTAAGAACTTAGCTCCTGTAATAATAATAATACTCACAGTTACATTATTAGGAAT
AAGACAATTATATAAAAATTCTATGAAAACTTCTGAAGAAGATAAGAAAAAAATTATGGCTTTAGATGAAAGTAAAGCTA
TTCGTGATATGTCTCTTATGAAAAAATGCTTAACAGTACTATTTTTAACTTTAATAGGATTCTTAACTCATAGTTATTTA
GGTTTTGAATCTGCAACTATCGCTATAGCTGGTTCTGCTATATTATTAGCTATAAGCAAAGTAGAACCAGATGAAATACT
ACAAGAAACAGAATGGGGTACTATATTCTTTTTCATAGGTTTATTTATAATGACTGGAGTTTTAGAAGATGTTGGCATCA
TGGAAGTCTTAGCACAGAAAACGTTGTCACTAACAAAAGGCAACCTAGTTATGACGGGAATATTTGTGCTTTGGATATCT
GCTATTGCCTCTGCATTTATAGATAATATTCCTTTTGTAGCTACTATGATACCTTTAATAAAAGCTATGGGCACCATGGG
TGGTATGGATATAGTTCCACTTTGGTGGGCATTATCTTTAGGTGCTTGTCTTGGTGGAAATGGAACTATGATCGGAGCTT
CTGCCAACCTAGTAGTAATTGGCATAGCAGAAAAAAGTGGTTATAAAATTTCTTTTAAAGACTACTTTAAACTTGGGTTT
CCTGTAATGTTAGTATCAATAATAATATGTACCGCTTACCTTTTAATGTTTTTTTTGAAATAA

Upstream 100 bases:

>100_bases
TTGAAAAGGGGTTTATTTATTTCCAAATTCGTATTAAAATCTAGAGGTACGTACTAAAATTTTTTATAGGGGGATGATTA
AAATATTTAGTAATTTTAAC

Downstream 100 bases:

>100_bases
TTTTGAGATGATTTCAAAATTATTTTATAATATTTTGAAAATTGTGGATATTGACGCTCGCTTAATGATATAATATAAAC
AAAGGATAACTCACTTAATT

Product: arsenical pump family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MMLPAIIFIIVYALIISEKVNRVVASLGGAAIMLILKLITQEKAFLKIDFNTIGLLVGMMIIVNITKRTGVFEYIAIKAA
KFSKGNPIKILILFSVITAVLSGVLDNVTTVLLIVPVTLVITKTLEIDPIPFLMCEIFASNIGGTATLIGDPPNLMIGSA
AGLSFLDFVKNLAPVIIIILTVTLLGIRQLYKNSMKTSEEDKKKIMALDESKAIRDMSLMKKCLTVLFLTLIGFLTHSYL
GFESATIAIAGSAILLAISKVEPDEILQETEWGTIFFFIGLFIMTGVLEDVGIMEVLAQKTLSLTKGNLVMTGIFVLWIS
AIASAFIDNIPFVATMIPLIKAMGTMGGMDIVPLWWALSLGACLGGNGTMIGASANLVVIGIAEKSGYKISFKDYFKLGF
PVMLVSIIICTAYLLMFFLK

Sequences:

>Translated_420_residues
MMLPAIIFIIVYALIISEKVNRVVASLGGAAIMLILKLITQEKAFLKIDFNTIGLLVGMMIIVNITKRTGVFEYIAIKAA
KFSKGNPIKILILFSVITAVLSGVLDNVTTVLLIVPVTLVITKTLEIDPIPFLMCEIFASNIGGTATLIGDPPNLMIGSA
AGLSFLDFVKNLAPVIIIILTVTLLGIRQLYKNSMKTSEEDKKKIMALDESKAIRDMSLMKKCLTVLFLTLIGFLTHSYL
GFESATIAIAGSAILLAISKVEPDEILQETEWGTIFFFIGLFIMTGVLEDVGIMEVLAQKTLSLTKGNLVMTGIFVLWIS
AIASAFIDNIPFVATMIPLIKAMGTMGGMDIVPLWWALSLGACLGGNGTMIGASANLVVIGIAEKSGYKISFKDYFKLGF
PVMLVSIIICTAYLLMFFLK
>Mature_420_residues
MMLPAIIFIIVYALIISEKVNRVVASLGGAAIMLILKLITQEKAFLKIDFNTIGLLVGMMIIVNITKRTGVFEYIAIKAA
KFSKGNPIKILILFSVITAVLSGVLDNVTTVLLIVPVTLVITKTLEIDPIPFLMCEIFASNIGGTATLIGDPPNLMIGSA
AGLSFLDFVKNLAPVIIIILTVTLLGIRQLYKNSMKTSEEDKKKIMALDESKAIRDMSLMKKCLTVLFLTLIGFLTHSYL
GFESATIAIAGSAILLAISKVEPDEILQETEWGTIFFFIGLFIMTGVLEDVGIMEVLAQKTLSLTKGNLVMTGIFVLWIS
AIASAFIDNIPFVATMIPLIKAMGTMGGMDIVPLWWALSLGACLGGNGTMIGASANLVVIGIAEKSGYKISFKDYFKLGF
PVMLVSIIICTAYLLMFFLK

Specific function: Unknown

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Homo sapiens, GI157266326, Length=490, Percent_Identity=35.7142857142857, Blast_Score=250, Evalue=2e-66,
Organism=Escherichia coli, GI1787039, Length=363, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87082277, Length=386, Percent_Identity=22.020725388601, Blast_Score=62, Evalue=5e-11,
Organism=Drosophila melanogaster, GI28574683, Length=487, Percent_Identity=33.6755646817248, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI28574681, Length=487, Percent_Identity=33.6755646817248, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI28574685, Length=487, Percent_Identity=33.6755646817248, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI28574678, Length=487, Percent_Identity=33.6755646817248, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24581759, Length=493, Percent_Identity=33.4685598377282, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI19920704, Length=487, Percent_Identity=33.6755646817248, Blast_Score=246, Evalue=1e-65,
Organism=Drosophila melanogaster, GI45550608, Length=476, Percent_Identity=33.6134453781513, Blast_Score=204, Evalue=8e-53,
Organism=Drosophila melanogaster, GI221472711, Length=497, Percent_Identity=27.7665995975855, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI85724998, Length=468, Percent_Identity=25.4273504273504, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI62484377, Length=468, Percent_Identity=25.4273504273504, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24656008, Length=475, Percent_Identity=27.1578947368421, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24581764, Length=159, Percent_Identity=41.5094339622642, Blast_Score=128, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 45445; Mature: 45445

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLPAIIFIIVYALIISEKVNRVVASLGGAAIMLILKLITQEKAFLKIDFNTIGLLVGMM
CCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHH
IIVNITKRTGVFEYIAIKAAKFSKGNPIKILILFSVITAVLSGVLDNVTTVLLIVPVTLV
HHHHHHHHCCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITKTLEIDPIPFLMCEIFASNIGGTATLIGDPPNLMIGSAAGLSFLDFVKNLAPVIIIIL
HHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHH
TVTLLGIRQLYKNSMKTSEEDKKKIMALDESKAIRDMSLMKKCLTVLFLTLIGFLTHSYL
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFESATIAIAGSAILLAISKVEPDEILQETEWGTIFFFIGLFIMTGVLEDVGIMEVLAQK
CCCCCEEEEECHHHEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSLTKGNLVMTGIFVLWISAIASAFIDNIPFVATMIPLIKAMGTMGGMDIVPLWWALSL
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GACLGGNGTMIGASANLVVIGIAEKSGYKISFKDYFKLGFPVMLVSIIICTAYLLMFFLK
HHHCCCCCCEEECCCCEEEEEEECCCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMLPAIIFIIVYALIISEKVNRVVASLGGAAIMLILKLITQEKAFLKIDFNTIGLLVGMM
CCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHH
IIVNITKRTGVFEYIAIKAAKFSKGNPIKILILFSVITAVLSGVLDNVTTVLLIVPVTLV
HHHHHHHHCCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITKTLEIDPIPFLMCEIFASNIGGTATLIGDPPNLMIGSAAGLSFLDFVKNLAPVIIIIL
HHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHH
TVTLLGIRQLYKNSMKTSEEDKKKIMALDESKAIRDMSLMKKCLTVLFLTLIGFLTHSYL
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFESATIAIAGSAILLAISKVEPDEILQETEWGTIFFFIGLFIMTGVLEDVGIMEVLAQK
CCCCCEEEEECHHHEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSLTKGNLVMTGIFVLWISAIASAFIDNIPFVATMIPLIKAMGTMGGMDIVPLWWALSL
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GACLGGNGTMIGASANLVVIGIAEKSGYKISFKDYFKLGFPVMLVSIIICTAYLLMFFLK
HHHCCCCCCEEECCCCEEEEEEECCCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]