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The map label for this gene is hypB [H]

Identifier: 226947667

GI number: 226947667

Start: 554290

End: 554961

Strand: Direct

Name: hypB [H]

Synonym: CLM_0511

Alternate gene names: 226947667

Gene position: 554290-554961 (Clockwise)

Preceding gene: 226947665

Following gene: 226947668

Centisome position: 13.34

GC content: 31.85

Gene sequence:

>672_bases
ATGAAGACATATAAAGTTCTAGAAATTAAACAAAGTGTTTTCGAAAATAATGATCGCCAAGCAGAGTTACTTAGAGAAGA
ATTGAAAAAAAAAGGGATATTTTTATTAAATCTTATGTCATCACCTGGCTCAGGAAAAACAACAACTCTTTTAAGAACAG
TTAAGGCTTTGAAAAATGAAATGAATATTGGGGTTCTGGAAGCAGATATTGATTCAGATGTAGATGCAAATAAGGTTTCA
CAGTCTGGTGTTAAAGTAATTCAGCTACACACTGGAGGAATGTGTCATCTTGACGCTGAAATGACAAGACAAAGTTTAAA
TGGTCTTGGGATTGAGAATATTGATTTAGCAATATTAGAGAATATTGGGAATTTAGTATGTCCTGCAGAGTTTGATACTG
GTGCATCAAGAAATGCTATGATTTTAAGCATACCAGAAGGGGATGATAAACCCTTAAAATATCCTTTAATGTTTTCAATA
GTTGATGTTCTACTGATTAATAAAATAGATGCAAAGGACTATTTTCAATTTGATTTGGAAGCAGTAAAAGAAAGGGTAAG
AAAATTAAATCCAAATATTAAGGTTATTCCAATTTCAGCAAAGACTGGAGAGGGAATTGAAGAATGGATTGATTGGATAC
GCAAAGAAGTAAAGATTTGGAAAGAAAGTTAA

Upstream 100 bases:

>100_bases
TATAAACATAACAGTTGTTATGTTATATTATGGTATATATGTATATATTATGATATTGATAGAGTATAACTTAAATTATA
TATAAAATGGGGGGATATGT

Downstream 100 bases:

>100_bases
GTAAAAATTTATAATGTTACTAATGACATAAAAAATTCTTATATAATTCTGATGATATATAATAATCAGCTTTTCCGGTT
ATTTTTGTTTTAAAAACTTA

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKTYKVLEIKQSVFENNDRQAELLREELKKKGIFLLNLMSSPGSGKTTTLLRTVKALKNEMNIGVLEADIDSDVDANKVS
QSGVKVIQLHTGGMCHLDAEMTRQSLNGLGIENIDLAILENIGNLVCPAEFDTGASRNAMILSIPEGDDKPLKYPLMFSI
VDVLLINKIDAKDYFQFDLEAVKERVRKLNPNIKVIPISAKTGEGIEEWIDWIRKEVKIWKES

Sequences:

>Translated_223_residues
MKTYKVLEIKQSVFENNDRQAELLREELKKKGIFLLNLMSSPGSGKTTTLLRTVKALKNEMNIGVLEADIDSDVDANKVS
QSGVKVIQLHTGGMCHLDAEMTRQSLNGLGIENIDLAILENIGNLVCPAEFDTGASRNAMILSIPEGDDKPLKYPLMFSI
VDVLLINKIDAKDYFQFDLEAVKERVRKLNPNIKVIPISAKTGEGIEEWIDWIRKEVKIWKES
>Mature_223_residues
MKTYKVLEIKQSVFENNDRQAELLREELKKKGIFLLNLMSSPGSGKTTTLLRTVKALKNEMNIGVLEADIDSDVDANKVS
QSGVKVIQLHTGGMCHLDAEMTRQSLNGLGIENIDLAILENIGNLVCPAEFDTGASRNAMILSIPEGDDKPLKYPLMFSI
VDVLLINKIDAKDYFQFDLEAVKERVRKLNPNIKVIPISAKTGEGIEEWIDWIRKEVKIWKES

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=216, Percent_Identity=40.7407407407407, Blast_Score=187, Evalue=7e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 25029; Mature: 25029

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYKVLEIKQSVFENNDRQAELLREELKKKGIFLLNLMSSPGSGKTTTLLRTVKALKNE
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHC
MNIGVLEADIDSDVDANKVSQSGVKVIQLHTGGMCHLDAEMTRQSLNGLGIENIDLAILE
CCCEEEEECCCCCCCHHHHHCCCCEEEEEECCCEEEECHHHHHHHHCCCCCCCHHHHHHH
NIGNLVCPAEFDTGASRNAMILSIPEGDDKPLKYPLMFSIVDVLLINKIDAKDYFQFDLE
HCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
AVKERVRKLNPNIKVIPISAKTGEGIEEWIDWIRKEVKIWKES
HHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTYKVLEIKQSVFENNDRQAELLREELKKKGIFLLNLMSSPGSGKTTTLLRTVKALKNE
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHC
MNIGVLEADIDSDVDANKVSQSGVKVIQLHTGGMCHLDAEMTRQSLNGLGIENIDLAILE
CCCEEEEECCCCCCCHHHHHCCCCEEEEEECCCEEEECHHHHHHHHCCCCCCCHHHHHHH
NIGNLVCPAEFDTGASRNAMILSIPEGDDKPLKYPLMFSIVDVLLINKIDAKDYFQFDLE
HCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
AVKERVRKLNPNIKVIPISAKTGEGIEEWIDWIRKEVKIWKES
HHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]