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The map label for this gene is fhuG [H]

Identifier: 226947544

GI number: 226947544

Start: 400820

End: 401827

Strand: Direct

Name: fhuG [H]

Synonym: CLM_0380

Alternate gene names: 226947544

Gene position: 400820-401827 (Clockwise)

Preceding gene: 226947543

Following gene: 226947545

Centisome position: 9.65

GC content: 31.45

Gene sequence:

>1008_bases
ATGAAGAAATGTGGCATGTATAAAAAAATAGCAACAATTTTTGCTTTAACTTTACTTTTATTTGTAGCAATTATTATTAG
TATGAATTTAGGTAAGATGAATTTAGCTCCTAATGAAGTACTAAATGTAATTTTAGGTAAGGGAACGGATAAACAAAATT
TGATTGTATTTGAATTTCGTTTACCGCGTATTGTTTTATCTATACTTGTAGGTATAGGTATGGCCATATCAGGATGTATT
TTACAAGCTTTATTTAGAAATGATTTAGCTGATCCAGGAATTTTAGGTATAAGCTCAGGCTCTGGTCTATTTATACTTAT
TTATATATCCATATTTTCAGTGAAAGGAATTCCTTCTGCTATTGCTTTACCCTTATTATCCTTTGTAGGTGGTATGATTG
CCGCCATACTTATTTATATATTATCCTATAAACGTAATTCTGATATATCCCCAACAAGACTTGTACTTACGGGTGTAGCT
ATGAATACTGGATTTGGAGCCATGTCTCTTTTTATTACATTAAAGTTAGATAGAAATCAATTTGAGTTTGCGCAAAAATT
GTTAGTAGGAAGTCTTTGGGGGGATGATTGGAAATATATAATTATTTTATTACCATGGATAATTATGTTTTCTTTATATG
TATTTTATAAAGCAAGGGCTTTAAATGTACTTAATTTAGGAAACCAATTAGCAACAGGACTTGGGATTCCAGTAAAGAAA
GATTTTTTAGCACTATCAATTGCAGCTGTAGCTTTAGCATCAGGAAGTGCAGCCTTAGGTGGATCTATGTTTTTTATTGG
ACTTATTTCTCCACATATTGCACGAAAGCTTGTAGGACCTAATCATAAAGTACTTATTCCAAGCTGCGCTTTAATTGGAT
CACTGATTATGATTATAGCGGATACAATAACACGTACTGTCAGTTTTGGAGCAGATATGCCCACAGGTATAATTCTAACA
ATAATTAGTACTCCTTATTTTATATATCTTTTAGCTCGGTCAAACTAA

Upstream 100 bases:

>100_bases
TAATTAATAGACCATATGAGACTCCACTAGGAATAATATTTGCTATTATAGGAGTACCTTTCTTTCTCTATATATCTCGC
AGAGAAAGGAGAGCTTTTGA

Downstream 100 bases:

>100_bases
TTGCTCATTTATATAGAAAGTAGGTAATAAATTATGAATAGCATAAAAGTGGAAAATCTATCTATTGCTTATGATGAAAG
CATAATAGTAGAAAACTTAA

Product: ferrichrome transport system permease FhuG

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKKCGMYKKIATIFALTLLLFVAIIISMNLGKMNLAPNEVLNVILGKGTDKQNLIVFEFRLPRIVLSILVGIGMAISGCI
LQALFRNDLADPGILGISSGSGLFILIYISIFSVKGIPSAIALPLLSFVGGMIAAILIYILSYKRNSDISPTRLVLTGVA
MNTGFGAMSLFITLKLDRNQFEFAQKLLVGSLWGDDWKYIIILLPWIIMFSLYVFYKARALNVLNLGNQLATGLGIPVKK
DFLALSIAAVALASGSAALGGSMFFIGLISPHIARKLVGPNHKVLIPSCALIGSLIMIIADTITRTVSFGADMPTGIILT
IISTPYFIYLLARSN

Sequences:

>Translated_335_residues
MKKCGMYKKIATIFALTLLLFVAIIISMNLGKMNLAPNEVLNVILGKGTDKQNLIVFEFRLPRIVLSILVGIGMAISGCI
LQALFRNDLADPGILGISSGSGLFILIYISIFSVKGIPSAIALPLLSFVGGMIAAILIYILSYKRNSDISPTRLVLTGVA
MNTGFGAMSLFITLKLDRNQFEFAQKLLVGSLWGDDWKYIIILLPWIIMFSLYVFYKARALNVLNLGNQLATGLGIPVKK
DFLALSIAAVALASGSAALGGSMFFIGLISPHIARKLVGPNHKVLIPSCALIGSLIMIIADTITRTVSFGADMPTGIILT
IISTPYFIYLLARSN
>Mature_335_residues
MKKCGMYKKIATIFALTLLLFVAIIISMNLGKMNLAPNEVLNVILGKGTDKQNLIVFEFRLPRIVLSILVGIGMAISGCI
LQALFRNDLADPGILGISSGSGLFILIYISIFSVKGIPSAIALPLLSFVGGMIAAILIYILSYKRNSDISPTRLVLTGVA
MNTGFGAMSLFITLKLDRNQFEFAQKLLVGSLWGDDWKYIIILLPWIIMFSLYVFYKARALNVLNLGNQLATGLGIPVKK
DFLALSIAAVALASGSAALGGSMFFIGLISPHIARKLVGPNHKVLIPSCALIGSLIMIIADTITRTVSFGADMPTGIILT
IISTPYFIYLLARSN

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=328, Percent_Identity=33.5365853658537, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1788004, Length=290, Percent_Identity=33.448275862069, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1786805, Length=309, Percent_Identity=29.4498381877023, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786804, Length=258, Percent_Identity=28.6821705426357, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1786347, Length=339, Percent_Identity=27.4336283185841, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790741, Length=324, Percent_Identity=29.0123456790123, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36106; Mature: 36106

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKCGMYKKIATIFALTLLLFVAIIISMNLGKMNLAPNEVLNVILGKGTDKQNLIVFEFR
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEC
LPRIVLSILVGIGMAISGCILQALFRNDLADPGILGISSGSGLFILIYISIFSVKGIPSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEEHHHHCCCCCHH
IALPLLSFVGGMIAAILIYILSYKRNSDISPTRLVLTGVAMNTGFGAMSLFITLKLDRNQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEEEEEHHCCCCCEEEEEEEEEECCCH
FEFAQKLLVGSLWGDDWKYIIILLPWIIMFSLYVFYKARALNVLNLGNQLATGLGIPVKK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHH
DFLALSIAAVALASGSAALGGSMFFIGLISPHIARKLVGPNHKVLIPSCALIGSLIMIIA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHCCCCCEEEECHHHHHHHHHHHHH
DTITRTVSFGADMPTGIILTIISTPYFIYLLARSN
HHHHHHHHCCCCCCCHHHHHHHCCCEEEEEEEECC
>Mature Secondary Structure
MKKCGMYKKIATIFALTLLLFVAIIISMNLGKMNLAPNEVLNVILGKGTDKQNLIVFEFR
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEC
LPRIVLSILVGIGMAISGCILQALFRNDLADPGILGISSGSGLFILIYISIFSVKGIPSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEEHHHHCCCCCHH
IALPLLSFVGGMIAAILIYILSYKRNSDISPTRLVLTGVAMNTGFGAMSLFITLKLDRNQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEEEEEHHCCCCCEEEEEEEEEECCCH
FEFAQKLLVGSLWGDDWKYIIILLPWIIMFSLYVFYKARALNVLNLGNQLATGLGIPVKK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHH
DFLALSIAAVALASGSAALGGSMFFIGLISPHIARKLVGPNHKVLIPSCALIGSLIMIIA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHCCCCCEEEECHHHHHHHHHHHHH
DTITRTVSFGADMPTGIILTIISTPYFIYLLARSN
HHHHHHHHCCCCCCCHHHHHHHCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]