Click here to switch to the map view.

The map label for this gene is thrS [H]

Identifier: 226947417

GI number: 226947417

Start: 228436

End: 230094

Strand: Direct

Name: thrS [H]

Synonym: CLM_0245

Alternate gene names: 226947417

Gene position: 228436-230094 (Clockwise)

Preceding gene: 226947413

Following gene: 226947418

Centisome position: 5.5

GC content: 26.94

Gene sequence:

>1659_bases
ATGGAGGGATTAAAATTATATATGCCTAATGGTAGTAATATTCTAGTATCTGGAGATAAAACCTTATATGATGTAGTAAA
AGAAAATAAATTACAAGATAATATACCTATTGTTTTAGGAAAAATAGATGAAGAATATTATGAACTAACTTCCACAGTGA
AAAAAGAGGGAGTATTCATTCCTGTAGATATAACAGATAGCATGGGATTAAAAACTTATGTTAGAACTTTGCAGTTTATA
TTTATAAAGGCGGTTTTGGATTTATATCCTGAATCTACTGTTGTTATAGAGCATTCTTTAGGCAAAGGACTATATGGTGA
AATTCATAAGACGCTATCACTAAATGAAAATGACATATTAAAGATTAAAAATAGAATGAATGAAATAATAAATAAAGACA
TAAAGATAAAAAAAATTTCAGTTAAAAAAGAAAGAGCTATAGAAATATTTAATGAATATAAAATGAAAGATAAAGTTAGA
CTTTTAAATCATATTCCACATGAAGAAGTGAAACTATATGAATTAGATGGAAGATATGATTATTTTTATGGACCTATGGC
ATATTCAACAGGGGCAATTAAAAATTTTGATATTATGTATTATGATCCAGGTTTTATATTAAGATACCCTAGAGAAAAAG
ATCCATTTAATATACCAGAGTTTGTTGAATATAAAAAGCTTACGAAAATATTTAGAGAAACAGAAAAATGGGCTAAAATT
TTAGATGTAGGGGATGTAGGAGCCCTAAACGATAAAGTTGTATATGGCGAAATAAAAGATATAATAAGAGTATCAGAGGC
CCTGCATGAAAAGAAAATAGCAAACATAGCAGATATGATATATGATAAAGAAAACATAAAAATGGTATTAATATCAGGAC
CTTCATCATCAGGAAAAACTACCTTTGCTAATAGATTAGGAATTCAATTAAGAGTTAACGCTTTGATACCTGTGCCTATT
TCATTAGATAATTATTTTGTTAATAGAGAGGATACTCCCAAAGATGAAAATGGAGATTATGATTTTGAATCCATTGATGC
TCTAGATATAGATTTATTTAATGAAGATTTAAAACATATATTAAACGGAGAAGAGGTACAAATACCTACTTTCAACTTTA
AAAAAGGTAAAAGGGAATATGATGGTAAAAAGATAAAACTTCCTAAAAGTGGGATACTCATTGTAGAGGGAATACATGGA
TTAAATCCAATATTAACAAGAGAAATACCGGATAAAAATAAATTTAAAATATATATAAGTGCATTAACTCAATTAAATAT
AGATAATCATAACAGAGTATCTACAACAGATGTAAGGATAATAAGAAGACTAGTTAGAGATTATTTATCAAGGGGTTATA
AAGGAGAAGAAACCTTAAAAATGTGGCCATCTATAAAAAGAGGAGAAGATAGAAATATATTTGTATTTCAAGAAAATGCA
GATGTAATGTTTAATTCCACAATAGTCTATGAACTTTGTATATTAAAAAAATATGCTCTTGCAGAACTTAACAAAATAGA
TAAAAACAGTACTGTTCATTATGAAGCAACTAGGTTAAAAAGTTTTTTAAACTTTTTTAAAGAAGTTGATATGAACTTAG
TTCCAGGTAATTCTATATTAAGGGAATTTATAGGTGGAAGTTGCTTCTATGAATATTAA

Upstream 100 bases:

>100_bases
TGTGGCAAATTTAAATAAAAAATATGAATGAATATAGGTAACAAAATATAATAAATTGAATTATAATAATAGTACAGCCT
AAAATAAGGAGATGAATAAA

Downstream 100 bases:

>100_bases
TGAAATAAGGAAAGTGCGCTGCACTTTCCTTATTTTTTGTCAGTAACAACTTTATGAGGTAAGAATAAAATGAATATAAA
TAAAAATATTTTAAAGTATA

Product: putative threonyl-tRNA synthetase/uridine kinase

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MEGLKLYMPNGSNILVSGDKTLYDVVKENKLQDNIPIVLGKIDEEYYELTSTVKKEGVFIPVDITDSMGLKTYVRTLQFI
FIKAVLDLYPESTVVIEHSLGKGLYGEIHKTLSLNENDILKIKNRMNEIINKDIKIKKISVKKERAIEIFNEYKMKDKVR
LLNHIPHEEVKLYELDGRYDYFYGPMAYSTGAIKNFDIMYYDPGFILRYPREKDPFNIPEFVEYKKLTKIFRETEKWAKI
LDVGDVGALNDKVVYGEIKDIIRVSEALHEKKIANIADMIYDKENIKMVLISGPSSSGKTTFANRLGIQLRVNALIPVPI
SLDNYFVNREDTPKDENGDYDFESIDALDIDLFNEDLKHILNGEEVQIPTFNFKKGKREYDGKKIKLPKSGILIVEGIHG
LNPILTREIPDKNKFKIYISALTQLNIDNHNRVSTTDVRIIRRLVRDYLSRGYKGEETLKMWPSIKRGEDRNIFVFQENA
DVMFNSTIVYELCILKKYALAELNKIDKNSTVHYEATRLKSFLNFFKEVDMNLVPGNSILREFIGGSCFYEY

Sequences:

>Translated_552_residues
MEGLKLYMPNGSNILVSGDKTLYDVVKENKLQDNIPIVLGKIDEEYYELTSTVKKEGVFIPVDITDSMGLKTYVRTLQFI
FIKAVLDLYPESTVVIEHSLGKGLYGEIHKTLSLNENDILKIKNRMNEIINKDIKIKKISVKKERAIEIFNEYKMKDKVR
LLNHIPHEEVKLYELDGRYDYFYGPMAYSTGAIKNFDIMYYDPGFILRYPREKDPFNIPEFVEYKKLTKIFRETEKWAKI
LDVGDVGALNDKVVYGEIKDIIRVSEALHEKKIANIADMIYDKENIKMVLISGPSSSGKTTFANRLGIQLRVNALIPVPI
SLDNYFVNREDTPKDENGDYDFESIDALDIDLFNEDLKHILNGEEVQIPTFNFKKGKREYDGKKIKLPKSGILIVEGIHG
LNPILTREIPDKNKFKIYISALTQLNIDNHNRVSTTDVRIIRRLVRDYLSRGYKGEETLKMWPSIKRGEDRNIFVFQENA
DVMFNSTIVYELCILKKYALAELNKIDKNSTVHYEATRLKSFLNFFKEVDMNLVPGNSILREFIGGSCFYEY
>Mature_552_residues
MEGLKLYMPNGSNILVSGDKTLYDVVKENKLQDNIPIVLGKIDEEYYELTSTVKKEGVFIPVDITDSMGLKTYVRTLQFI
FIKAVLDLYPESTVVIEHSLGKGLYGEIHKTLSLNENDILKIKNRMNEIINKDIKIKKISVKKERAIEIFNEYKMKDKVR
LLNHIPHEEVKLYELDGRYDYFYGPMAYSTGAIKNFDIMYYDPGFILRYPREKDPFNIPEFVEYKKLTKIFRETEKWAKI
LDVGDVGALNDKVVYGEIKDIIRVSEALHEKKIANIADMIYDKENIKMVLISGPSSSGKTTFANRLGIQLRVNALIPVPI
SLDNYFVNREDTPKDENGDYDFESIDALDIDLFNEDLKHILNGEEVQIPTFNFKKGKREYDGKKIKLPKSGILIVEGIHG
LNPILTREIPDKNKFKIYISALTQLNIDNHNRVSTTDVRIIRRLVRDYLSRGYKGEETLKMWPSIKRGEDRNIFVFQENA
DVMFNSTIVYELCILKKYALAELNKIDKNSTVHYEATRLKSFLNFFKEVDMNLVPGNSILREFIGGSCFYEY

Specific function: Unknown

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR012675
- InterPro:   IPR004095
- InterPro:   IPR012676
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF02824 TGS; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 63936; Mature: 63936

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGLKLYMPNGSNILVSGDKTLYDVVKENKLQDNIPIVLGKIDEEYYELTSTVKKEGVFI
CCCCEEECCCCCEEEEECCHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCEEE
PVDITDSMGLKTYVRTLQFIFIKAVLDLYPESTVVIEHSLGKGLYGEIHKTLSLNENDIL
EEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCCCHH
KIKNRMNEIINKDIKIKKISVKKERAIEIFNEYKMKDKVRLLNHIPHEEVKLYELDGRYD
HHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEE
YFYGPMAYSTGAIKNFDIMYYDPGFILRYPREKDPFNIPEFVEYKKLTKIFRETEKWAKI
EEECCHHCCCCCCCCEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LDVGDVGALNDKVVYGEIKDIIRVSEALHEKKIANIADMIYDKENIKMVLISGPSSSGKT
HCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
TFANRLGIQLRVNALIPVPISLDNYFVNREDTPKDENGDYDFESIDALDIDLFNEDLKHI
CHHHHCCEEEEEEEEEECEEECCCEEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHH
LNGEEVQIPTFNFKKGKREYDGKKIKLPKSGILIVEGIHGLNPILTREIPDKNKFKIYIS
HCCCEEEECCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCHHCCCCCCCCCEEEEEE
ALTQLNIDNHNRVSTTDVRIIRRLVRDYLSRGYKGEETLKMWPSIKRGEDRNIFVFQENA
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCEEEEEECCC
DVMFNSTIVYELCILKKYALAELNKIDKNSTVHYEATRLKSFLNFFKEVDMNLVPGNSIL
CEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHCCCEECCCHHHH
REFIGGSCFYEY
HHHHCCCEEECC
>Mature Secondary Structure
MEGLKLYMPNGSNILVSGDKTLYDVVKENKLQDNIPIVLGKIDEEYYELTSTVKKEGVFI
CCCCEEECCCCCEEEEECCHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCEEE
PVDITDSMGLKTYVRTLQFIFIKAVLDLYPESTVVIEHSLGKGLYGEIHKTLSLNENDIL
EEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCCCHH
KIKNRMNEIINKDIKIKKISVKKERAIEIFNEYKMKDKVRLLNHIPHEEVKLYELDGRYD
HHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEE
YFYGPMAYSTGAIKNFDIMYYDPGFILRYPREKDPFNIPEFVEYKKLTKIFRETEKWAKI
EEECCHHCCCCCCCCEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LDVGDVGALNDKVVYGEIKDIIRVSEALHEKKIANIADMIYDKENIKMVLISGPSSSGKT
HCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
TFANRLGIQLRVNALIPVPISLDNYFVNREDTPKDENGDYDFESIDALDIDLFNEDLKHI
CHHHHCCEEEEEEEEEECEEECCCEEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHH
LNGEEVQIPTFNFKKGKREYDGKKIKLPKSGILIVEGIHGLNPILTREIPDKNKFKIYIS
HCCCEEEECCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCHHCCCCCCCCCEEEEEE
ALTQLNIDNHNRVSTTDVRIIRRLVRDYLSRGYKGEETLKMWPSIKRGEDRNIFVFQENA
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCEEEEEECCC
DVMFNSTIVYELCILKKYALAELNKIDKNSTVHYEATRLKSFLNFFKEVDMNLVPGNSIL
CEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHCCCEECCCHHHH
REFIGGSCFYEY
HHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA