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The map label for this gene is atpD [H]

Identifier: 226947380

GI number: 226947380

Start: 184784

End: 186175

Strand: Direct

Name: atpD [H]

Synonym: CLM_0200

Alternate gene names: 226947380

Gene position: 184784-186175 (Clockwise)

Preceding gene: 226947379

Following gene: 226947381

Centisome position: 4.45

GC content: 33.55

Gene sequence:

>1392_bases
GTGTCAAATTTAGGTAAAGTAATACAAATAATAGGACCGATTATAGATATAAAATTTGATTCGGAAAATCTTCCAGATTT
GTTTAATGCATTAGAAATAAATGCTGGTGATAGAAAAGTTATAGCTGAAGTTGAACAACATATAGGGGATGATACTATTA
GAGCTATAGCCATGGAAGATACTGAAGGCCTAAAACGAGGTATGGAAGCTTTAGATACAGGGAAATCCGTTTCAGTACCA
GTAGGTAAAGAAGTTTTAGGACGATTGTTTAATGTTTTAGGAAAGCCTATAGATGGAGCAGGAGAATTTATATCAGAAGA
ATCCTATCCTATTCATAGGCCAGCTCCAAGTTTTGAGGAACAATCCGTAGAGCCAGAAATATTTGAAACAGGCATAAAAG
TAATAGATCTTTTAGCACCCTATGAAAAAGGTGGTAAAATAGGATTGTTTGGAGGAGCAGGAGTAGGAAAAACTGTATTA
ATACAAGAATTAATAAATAATATAGCTAAAGAGCATGGAGGATTATCAGTATTTACAGGTGTTGGAGAAAGAACAAGAGA
AGGAAATGATCTTTACTATGAAATGAAGGAATCAGGTGTTTTAGAAAAAACAGCATTAGTATTTGGTCAAATGAATGAAC
CACCAGGAGCTAGAATGAGGGTAGCCCTTACAGGTTTAACAATGTCAGAATATTTTAGAGACCAAGGTCAAGATGTATTA
TTATTTATAGATAACATTTTTAGATTTACTCAAGCAGGATCAGAAGTTTCAGCTCTTTTAGGAAGAATTCCAAGTGCCGT
TGGATATCAACCAACTTTAGCTACTGAGATGGGAGCGCTCCAAGAAAGAATAACATCTACAAAAAATGGTTCTATAACAT
CTGTTCAAGCAGTATATGTTCCAGCAGATGATTTAACAGATCCAGCACCAGCGACAACATTTGCTCATTTAGATGCTACA
ACAGTTTTATCCAGATCTATAACAGAACTTGGTATTTATCCAGCAGTAGATCCATTAGAATCTTCATCTAGAATGTTAGA
TCCTAGAATAATAGGCGAAGAACATTATGAGGTAGCTATAAAGGTTAAAAATATACTTGAAAGATATAGAGAACTTCAAG
ATATAATAGCTATATTGGGTATAGATGAACTTTCAGAAGAAGATAAGTTAGTGGTTGGCAGAGCAAGAAAAATACAAAGA
TTTTTATCTCAACCATTTACAGTAGCAGAACAATTTACAGGAATGCAGGGTAAATATGTGCCTATAAAAGAAACTGTTAG
AGGTTTTAAAGAAATATTGGAAGGCAAACATGATAATATTCCAGAATCAGCTTTTTTATTCCAAGGAACTATAGAAGATG
TTTTAAAGAAAGCACAACAAATGGAAATATAA

Upstream 100 bases:

>100_bases
TTAGATCTACAATTTAATAGATTAAGACAAAGTGCTATTACACAAGAAATATCAGAAATAGTTGGTGGTGCAGAAGCTCA
AAGGTAGGAGGTGTACTATA

Downstream 100 bases:

>100_bases
TTAGGTTAATAAGAGGAGAATAATATGAAAGATAATATAGAACTTACTATATTTACTCCTGAAAAAAATATTAAAATTGG
AGAGATAAAAGAAGTAATAA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSNLGKVIQIIGPIIDIKFDSENLPDLFNALEINAGDRKVIAEVEQHIGDDTIRAIAMEDTEGLKRGMEALDTGKSVSVP
VGKEVLGRLFNVLGKPIDGAGEFISEESYPIHRPAPSFEEQSVEPEIFETGIKVIDLLAPYEKGGKIGLFGGAGVGKTVL
IQELINNIAKEHGGLSVFTGVGERTREGNDLYYEMKESGVLEKTALVFGQMNEPPGARMRVALTGLTMSEYFRDQGQDVL
LFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGALQERITSTKNGSITSVQAVYVPADDLTDPAPATTFAHLDAT
TVLSRSITELGIYPAVDPLESSSRMLDPRIIGEEHYEVAIKVKNILERYRELQDIIAILGIDELSEEDKLVVGRARKIQR
FLSQPFTVAEQFTGMQGKYVPIKETVRGFKEILEGKHDNIPESAFLFQGTIEDVLKKAQQMEI

Sequences:

>Translated_463_residues
MSNLGKVIQIIGPIIDIKFDSENLPDLFNALEINAGDRKVIAEVEQHIGDDTIRAIAMEDTEGLKRGMEALDTGKSVSVP
VGKEVLGRLFNVLGKPIDGAGEFISEESYPIHRPAPSFEEQSVEPEIFETGIKVIDLLAPYEKGGKIGLFGGAGVGKTVL
IQELINNIAKEHGGLSVFTGVGERTREGNDLYYEMKESGVLEKTALVFGQMNEPPGARMRVALTGLTMSEYFRDQGQDVL
LFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGALQERITSTKNGSITSVQAVYVPADDLTDPAPATTFAHLDAT
TVLSRSITELGIYPAVDPLESSSRMLDPRIIGEEHYEVAIKVKNILERYRELQDIIAILGIDELSEEDKLVVGRARKIQR
FLSQPFTVAEQFTGMQGKYVPIKETVRGFKEILEGKHDNIPESAFLFQGTIEDVLKKAQQMEI
>Mature_462_residues
SNLGKVIQIIGPIIDIKFDSENLPDLFNALEINAGDRKVIAEVEQHIGDDTIRAIAMEDTEGLKRGMEALDTGKSVSVPV
GKEVLGRLFNVLGKPIDGAGEFISEESYPIHRPAPSFEEQSVEPEIFETGIKVIDLLAPYEKGGKIGLFGGAGVGKTVLI
QELINNIAKEHGGLSVFTGVGERTREGNDLYYEMKESGVLEKTALVFGQMNEPPGARMRVALTGLTMSEYFRDQGQDVLL
FIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGALQERITSTKNGSITSVQAVYVPADDLTDPAPATTFAHLDATT
VLSRSITELGIYPAVDPLESSSRMLDPRIIGEEHYEVAIKVKNILERYRELQDIIAILGIDELSEEDKLVVGRARKIQRF
LSQPFTVAEQFTGMQGKYVPIKETVRGFKEILEGKHDNIPESAFLFQGTIEDVLKKAQQMEI

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=464, Percent_Identity=68.9655172413793, Blast_Score=657, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=394, Percent_Identity=26.6497461928934, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI19913428, Length=361, Percent_Identity=26.0387811634349, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19913426, Length=357, Percent_Identity=25.4901960784314, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI50345984, Length=411, Percent_Identity=25.7907542579075, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI4757810, Length=411, Percent_Identity=25.7907542579075, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI1790170, Length=457, Percent_Identity=65.4266958424508, Blast_Score=634, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=312, Percent_Identity=30.7692307692308, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1790172, Length=401, Percent_Identity=26.9326683291771, Blast_Score=126, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI25144756, Length=464, Percent_Identity=68.3189655172414, Blast_Score=651, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=351, Percent_Identity=28.7749287749288, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17510931, Length=355, Percent_Identity=25.3521126760563, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=354, Percent_Identity=25.1412429378531, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71988080, Length=402, Percent_Identity=25.6218905472637, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=402, Percent_Identity=25.6218905472637, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988074, Length=383, Percent_Identity=24.5430809399478, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322581, Length=457, Percent_Identity=71.9912472647702, Blast_Score=662, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=352, Percent_Identity=26.9886363636364, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319370, Length=367, Percent_Identity=26.4305177111717, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320016, Length=230, Percent_Identity=27.3913043478261, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24638766, Length=464, Percent_Identity=68.75, Blast_Score=649, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=465, Percent_Identity=67.741935483871, Blast_Score=621, Evalue=1e-178,
Organism=Drosophila melanogaster, GI24583992, Length=349, Percent_Identity=27.2206303724928, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24583988, Length=349, Percent_Identity=26.647564469914, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24583986, Length=349, Percent_Identity=26.647564469914, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24583984, Length=349, Percent_Identity=26.647564469914, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI20129479, Length=346, Percent_Identity=26.5895953757225, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281361666, Length=405, Percent_Identity=25.679012345679, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646341, Length=405, Percent_Identity=25.679012345679, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17136796, Length=405, Percent_Identity=25.679012345679, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24658560, Length=418, Percent_Identity=25.8373205741627, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24638768, Length=91, Percent_Identity=49.4505494505495, Blast_Score=102, Evalue=6e-22,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 50789; Mature: 50657

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLGKVIQIIGPIIDIKFDSENLPDLFNALEINAGDRKVIAEVEQHIGDDTIRAIAMED
CCCHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCHHEEEEECC
TEGLKRGMEALDTGKSVSVPVGKEVLGRLFNVLGKPIDGAGEFISEESYPIHRPAPSFEE
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCHH
QSVEPEIFETGIKVIDLLAPYEKGGKIGLFGGAGVGKTVLIQELINNIAKEHGGLSVFTG
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEC
VGERTREGNDLYYEMKESGVLEKTALVFGQMNEPPGARMRVALTGLTMSEYFRDQGQDVL
CCCCCCCCCCEEEEEHHCCCHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHCCCCEEE
LFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGALQERITSTKNGSITSVQAVYV
EHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEE
PADDLTDPAPATTFAHLDATTVLSRSITELGIYPAVDPLESSSRMLDPRIIGEEHYEVAI
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCHHEEEH
KVKNILERYRELQDIIAILGIDELSEEDKLVVGRARKIQRFLSQPFTVAEQFTGMQGKYV
HHHHHHHHHHHHHHHHHHHCCHHCCCCCCEEHHHHHHHHHHHCCCHHHHHHHCCCCCCCC
PIKETVRGFKEILEGKHDNIPESAFLFQGTIEDVLKKAQQMEI
CHHHHHHHHHHHHCCCCCCCCCHHHEECCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNLGKVIQIIGPIIDIKFDSENLPDLFNALEINAGDRKVIAEVEQHIGDDTIRAIAMED
CCHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCHHEEEEECC
TEGLKRGMEALDTGKSVSVPVGKEVLGRLFNVLGKPIDGAGEFISEESYPIHRPAPSFEE
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCHH
QSVEPEIFETGIKVIDLLAPYEKGGKIGLFGGAGVGKTVLIQELINNIAKEHGGLSVFTG
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEC
VGERTREGNDLYYEMKESGVLEKTALVFGQMNEPPGARMRVALTGLTMSEYFRDQGQDVL
CCCCCCCCCCEEEEEHHCCCHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHCCCCEEE
LFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGALQERITSTKNGSITSVQAVYV
EHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEE
PADDLTDPAPATTFAHLDATTVLSRSITELGIYPAVDPLESSSRMLDPRIIGEEHYEVAI
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCHHEEEH
KVKNILERYRELQDIIAILGIDELSEEDKLVVGRARKIQRFLSQPFTVAEQFTGMQGKYV
HHHHHHHHHHHHHHHHHHHCCHHCCCCCCEEHHHHHHHHHHHCCCHHHHHHHCCCCCCCC
PIKETVRGFKEILEGKHDNIPESAFLFQGTIEDVLKKAQQMEI
CHHHHHHHHHHHHCCCCCCCCCHHHEECCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA